Best TWAS P=1.55e-08 · Best GWAS P=3.29e-07 conditioned to 0.163
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100505761 | 0.17 | 0.05 | lasso | 13 | 0.14 | 2.0e-16 | 5.0 | -5.7 | 1.5e-08 | -0.74 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Coronary | TMEM180 | 0.14 | 0.05 | enet | 13 | 0.04 | 2.4e-02 | -4.8 | -5.3 | 1.3e-07 | -0.54 | 0.04 | 0.78 | FALSE |
| 3 | GTEx | Breast Mammary Tissue | SFXN2 | 0.11 | 0.00 | enet | 12 | 0.03 | 1.3e-02 | -4.7 | 5.2 | 2.1e-07 | 0.50 | 0.05 | 0.68 | FALSE |
| 4 | GTEx | Esophagus Gastroesophageal Junction | TMEM180 | 0.22 | 0.23 | enet | 11 | 0.27 | 3.0e-10 | -4.7 | -5.3 | 1.3e-07 | -0.57 | 0.04 | 0.94 | FALSE |
| 5 | GTEx | Nerve Tibial | RP11-18I14.10 | 0.05 | 0.01 | enet | 8 | 0.02 | 1.4e-02 | 5.0 | -5.2 | 1.5e-07 | -0.67 | 0.04 | 0.71 | FALSE |