Best TWAS P=2.98e-15 · Best GWAS P=1.46e-14 conditioned to 0.336
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | ZNF318 | 0.04 | 0.03 | lasso | 8 | 0.02 | 1.3e-08 | -7.6 | -7.7 | 1.4e-14 | 0.95 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CRIP3 | 0.08 | 0.08 | blup | 34 | 0.07 | 1.0e-04 | -7.5 | -6.8 | 9.7e-12 | 0.94 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF318 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.1e-06 | -5.4 | 5.4 | 6.7e-08 | -0.74 | 0.74 | 0.17 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TTBK1 | 0.04 | 0.00 | blup | 52 | 0.01 | 3.8e-02 | -4.5 | 5.9 | 3.2e-09 | -0.50 | 0.03 | 0.07 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZNF318 | 0.04 | 0.02 | blup | 48 | 0.04 | 2.2e-03 | -7.6 | -7.9 | 3.0e-15 | 0.93 | 0.01 | 0.78 | TRUE |