Best TWAS P=2.26e-07 · Best GWAS P=2.47e-07 conditioned to 0.0445
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | ULK3 | 0.15 | 0.03 | enet | 24 | 0.06 | 1.6e-03 | -4.9 | -5.2 | 2.6e-07 | 0.71 | 0.04 | 0.91 | FALSE |
2 | GTEx | Thyroid | ULK3 | 0.11 | 0.09 | lasso | 4 | 0.13 | 5.9e-10 | -4.7 | -5.1 | 2.7e-07 | 0.74 | 0.07 | 0.92 | FALSE |
3 | GTEx | Uterus | ULK3 | 0.40 | 0.16 | lasso | 16 | 0.12 | 2.2e-03 | -4.4 | -5.2 | 2.3e-07 | 0.73 | 0.04 | 0.71 | TRUE |