Best TWAS P=8.08e-08 · Best GWAS P=4.5e-06 conditioned to 0.873
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | LRRC37A4P | 0.46 | 0.25 | enet | 37 | 0.33 | 5.3e-12 | 4.6 | -5.4 | 8.1e-08 | -0.84 | 0.01 | 0.96 | TRUE |
| 2 | GTEx | Colon Sigmoid | MAPT | 0.12 | 0.18 | enet | 18 | 0.17 | 1.1e-06 | 4.6 | -5.4 | 8.4e-08 | -0.93 | 0.01 | 0.96 | FALSE |
| 3 | GTEx | Spleen | CRHR1 | 0.29 | 0.36 | enet | 16 | 0.34 | 1.7e-09 | 4.5 | 5.2 | 1.8e-07 | 0.90 | 0.01 | 0.96 | FALSE |