Hub : Genes

MAPT

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0530	0.0240	4.1e-10	0.092	0.091	0.086	0.090	0.090	3.0e-11	3.4e-11	1.1e-10	4.1e-11	4.5e-11
2	GTEx	Artery Aorta	0.1390	0.0840	5.1e-05	0.082	NA	0.091	NA	0.070	2.7e-05	NA	1.0e-05	NA	1.0e-04
3	GTEx	Brain Cerebellar Hemisphere	0.2430	0.1050	1.2e-06	0.261	NA	0.204	NA	0.248	2.2e-07	NA	5.9e-06	NA	4.7e-07
4	GTEx	Brain Cerebellum	0.2160	0.0840	2.8e-09	0.330	NA	0.340	NA	0.328	1.6e-10	NA	7.9e-11	NA	1.9e-10
5	GTEx	Brain Cortex	0.1370	0.0760	3.4e-04	0.105	NA	0.071	NA	0.058	7.9e-04	NA	5.3e-03	NA	1.0e-02
6	GTEx	Brain Frontal Cortex BA9	0.1520	0.0779	1.2e-05	0.253	NA	0.255	NA	0.255	2.2e-07	NA	2.0e-07	NA	2.0e-07
7	GTEx	Cells Transformed fibroblasts	0.0350	0.0290	6.7e-03	0.030	NA	0.011	NA	0.018	2.3e-03	NA	5.0e-02	NA	1.7e-02
8	GTEx	Colon Sigmoid	0.1200	0.0580	1.1e-06	0.185	NA	0.172	NA	0.156	4.1e-07	NA	1.1e-06	NA	3.6e-06
9	GTEx	Colon Transverse	0.0910	0.0470	1.8e-05	0.122	NA	0.072	NA	0.084	2.1e-06	NA	2.5e-04	NA	8.0e-05
10	GTEx	Esophagus Mucosa	0.1550	0.0570	6.1e-16	0.263	NA	0.253	NA	0.268	1.0e-17	NA	5.5e-17	NA	4.3e-18
11	GTEx	Esophagus Muscularis	0.0400	0.0320	9.1e-03	0.016	NA	0.006	NA	0.013	3.7e-02	NA	1.3e-01	NA	5.1e-02
12	GTEx	Heart Left Ventricle	0.2370	0.0896	3.3e-09	0.162	NA	0.108	NA	0.136	5.3e-09	NA	2.2e-06	NA	1.1e-07
13	GTEx	Lung	0.0533	0.0258	2.3e-06	0.090	NA	0.081	NA	0.084	2.0e-07	NA	8.2e-07	NA	5.1e-07
14	GTEx	Muscle Skeletal	0.0602	0.0306	5.4e-06	0.027	NA	0.063	NA	0.053	1.0e-03	NA	8.7e-07	NA	6.3e-06
15	GTEx	Skin Sun Exposed Lower leg	0.0360	0.0310	3.8e-03	0.036	NA	0.019	NA	0.022	5.8e-04	NA	9.7e-03	NA	5.6e-03
16	GTEx	Testis	0.3180	0.0810	0.0e+00	0.536	NA	0.537	NA	0.530	1.0e-27	NA	9.4e-28	NA	3.2e-27
17	GTEx	Thyroid	0.0900	0.0540	4.9e-06	0.043	NA	0.046	NA	0.050	2.9e-04	NA	1.8e-04	NA	1.1e-04
18	GTEx	Uterus	0.1880	0.0910	1.7e-04	0.041	NA	0.080	NA	0.060	5.3e-02	NA	1.1e-02	NA	2.4e-02
19	METSIM	Adipose	0.0241	0.0135	2.2e-04	0.016	0.016	0.010	0.015	0.016	1.7e-03	1.5e-03	1.0e-02	2.4e-03	1.4e-03
20	TCGA	Glioblastoma Multiforme	0.1230	0.0710	9.6e-03	-0.001	0.050	0.034	NA	0.021	3.4e-01	1.3e-02	3.3e-02	NA	7.6e-02
21	TCGA	Brain Lower Grade Glioma	0.0862	0.0288	1.2e-11	0.125	0.111	0.112	NA	0.120	4.5e-14	1.5e-12	1.2e-12	NA	1.8e-13
22	TCGA	Lung Squamous Cell Carcinoma	0.0331	0.0153	3.3e-04	0.051	0.035	0.044	NA	0.049	1.6e-06	6.7e-05	9.3e-06	NA	2.5e-06
23	TCGA	Ovarian Serous Cystadenocarcinoma	0.0880	0.0380	1.3e-05	0.040	0.075	0.066	NA	0.063	1.1e-03	8.6e-06	3.2e-05	NA	4.8e-05
24	TCGA	Pheochromocytoma and Paraganglioma	0.2760	0.0970	4.9e-06	0.082	0.160	0.140	NA	0.120	3.8e-04	6.2e-07	3.5e-06	NA	1.7e-05
25	TCGA	Prostate Adenocarcinoma	0.0495	0.0251	5.9e-04	0.045	0.039	0.027	NA	0.043	1.7e-05	6.2e-05	7.0e-04	NA	2.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Bipolar Disorder (2018)	0.9	1.4	2.5	-1.4	-0.5	-1.1	-0.1	-1.6	-1.1	-1.1	-1.4	-0.9	1.1	-1.2	-1.6	1.1	-0.9	1.2	1.3	-1.4	-1.1	1.4	-1.3	-1.3	-1.1	-1.4	-1.1	-1.2
Bipolar Disorder or Schizophrenia	0.7	1.8	6.9	0.9	1.5	1.5	2.6	-0.1	1.5	1.6	1.2	1.6	-1.3	0.6	-0.5	-1.6	1.7	-0.9	-1.2	0.4	1.4	-0.3	1.1	1.5	1.7	1.3	0.7	1.6
Depressed Affect (Nagel 2018)	35.7	75.0	91.2	-9.1	-6.8	-9.5	-7.3	-8.7	-9.5	-9.4	-9.1	-9.4	9.2	-8.7	-7.3	9.4	-8.2	8.0	9.6	-9.0	-8.7	8.6	-7.1	-8.9	-9.1	-8.9	-7.1	-9.1
Depression (Nagel 2018)	10.1	15.2	19.5	-4.2	-2.8	-4.1	-2.5	-3.8	-4.0	-4.1	-4.4	-4.1	4.1	-4.3	-3.9	4.0	-3.5	3.8	4.4	-4.3	-4.2	4.3	-2.0	-3.8	-3.9	-4.3	-3.6	-3.9
Intelligence (Savage-Jansen 2018)	7.4	22.8	35.2	5.1	5.8	4.9	4.2	3.7	4.9	5.0	5.9	4.9	-5.0	5.5	4.9	-4.8	3.5	-4.8	-4.9	4.7	5.1	-4.9	4.1	4.3	4.1	5.4	3.5	4.2
Neuroticism (Nagel 2018)	43.4	102.2	123.0	-10.7	-8.6	-11.0	-8.8	-10.0	-11.0	-11.0	-10.9	-10.9	10.8	-10.2	-8.6	11.0	-9.8	9.6	11.1	-10.1	-10.4	9.9	-7.9	-10.1	-10.6	-10.7	-7.8	-10.1
Schizophrenia (2018)	3.1	6.5	11.4	2.3	2.3	2.9	3.4	1.2	2.9	2.9	2.7	2.9	-2.7	1.8	0.7	-2.9	3.0	-2.2	-2.7	1.5	2.7	-1.6	2.5	3.0	3.1	2.9	1.8	3.0
Schizophrenia vs Biploar Disorder	7.5	9.9	15.1	3.1	2.2	3.8	3.2	2.5	3.8	3.8	3.5	3.9	-3.6	2.8	1.4	-3.8	3.4	-2.8	-3.7	2.8	3.2	-2.4	2.8	3.0	3.1	3.7	1.8	2.9
Worry (Nagel 2018)	22.5	47.4	58.6	-7.6	-5.9	-7.4	-5.7	-7.1	-7.4	-7.4	-7.7	-7.2	7.4	-7.0	-6.3	7.4	-6.6	6.7	7.6	-7.2	-7.0	7.0	-4.7	-6.7	-6.9	-7.3	-5.3	-6.8
Alzheimer’s Disease (in mother)	0.1	0.1	1.0	0.0	0.1	0.1	-0.6	0.0	0.0	0.1	0.4	0.1	0.1	0.3	0.1	-0.0	-0.5	0.4	-0.1	-0.1	0.1	0.1	-0.3	0.1	0.2	0.3	1.0	0.3
Alzheimer’s Disease (in father)	1.0	1.1	3.3	1.1	1.1	1.0	0.9	1.3	1.0	1.0	1.0	1.0	-1.1	0.9	0.7	-1.0	1.2	-1.3	-1.0	0.6	1.1	-0.7	-0.1	0.9	0.9	1.1	1.8	0.8
Alzheimer’s Disease (including proxy)	0.9	1.3	4.1	1.0	1.3	0.7	0.5	0.8	0.6	1.7	1.3	0.7	-0.6	0.8	0.4	-0.6	0.5	-0.5	-1.0	1.2	0.9	-0.4	0.7	1.7	1.8	1.6	2.0	1.8
Crohns Disease (2017)	2.9	6.3	10.3	2.4	2.0	2.8	2.9	2.3	2.8	2.8	2.2	2.8	-2.8	2.4	1.6	-2.9	2.9	-2.5	-2.7	2.3	2.5	-2.3	3.2	2.3	2.3	2.2	1.9	2.2
Irritable Bowel Disease (IBD)	2.3	5.6	10.4	2.3	1.3	2.7	2.3	2.3	2.6	2.6	2.2	2.5	-2.6	2.0	1.6	-2.6	3.2	-2.5	-2.7	2.3	2.5	-2.3	2.9	2.1	2.2	1.8	1.9	2.0
Ulcerative Colitis (UC)	1.2	2.3	4.9	1.6	0.4	1.7	1.2	1.5	1.7	1.7	1.4	1.6	-1.8	1.4	1.1	-1.6	2.2	-1.8	-1.9	1.7	1.8	-1.7	1.7	1.3	1.4	0.5	1.1	1.1
Major Depression (MDD)	0.7	0.9	4.1	-0.5	-0.6	-0.4	-0.9	-1.0	-1.4	-0.4	-0.6	-0.4	1.2	-0.2	0.1	2.0	-1.2	1.9	0.4	-0.1	-0.6	0.1	-0.1	-1.5	-0.7	-0.3	-1.3	-0.7
Reaction Time	1.0	1.9	13.3	-1.5	-2.3	-0.8	-0.5	-0.6	-0.8	-0.8	-2.2	-0.7	0.5	-1.5	-2.5	0.8	-0.1	0.0	0.8	-0.8	-1.9	1.6	-0.6	-0.9	-1.0	-3.6	-0.1	-0.9
Verbal and Numeric Reasoning (VNR)	7.8	18.7	31.5	4.7	5.6	4.5	4.4	3.3	4.5	4.6	5.5	4.5	-4.6	4.8	4.4	-4.5	3.5	-4.4	-4.4	4.0	4.9	-4.5	3.4	3.4	3.3	4.3	3.1	3.4
Breast Cancer	12.6	30.4	40.7	-5.9	-5.0	-6.4	-5.4	-5.5	-6.3	-6.2	-5.6	-6.3	6.2	-5.6	-4.1	6.3	-5.3	5.4	6.2	-5.6	-5.3	5.2	-4.2	-5.0	-5.2	-4.9	-4.8	-5.0
Ovarian Cancer	32.3	42.7	54.5	6.6	6.0	7.1	7.3	6.3	7.1	7.1	6.5	7.3	-7.4	6.3	4.6	-7.1	6.5	-7.1	-6.8	6.3	6.1	-5.7	6.3	6.7	6.7	5.8	5.2	6.6
Prostate Cancer	2.1	3.0	4.6	1.6	1.0	1.9	1.6	1.7	1.9	1.9	1.7	2.1	-1.8	1.9	1.5	-1.9	1.4	-1.5	-1.9	1.8	1.8	-1.8	-0.0	1.7	1.8	2.1	1.4	1.8
Age at First Birth	4.1	6.0	9.1	2.5	1.8	2.7	2.6	2.4	2.7	2.6	2.6	2.5	-2.8	2.6	2.4	-2.7	2.1	-3.0	-2.6	3.0	2.1	-2.6	1.1	2.0	2.0	2.1	2.5	2.0
Bipolar Disorder (2011)	2.4	2.3	5.8	-2.2	-1.5	-1.5	-0.9	-2.2	-1.5	-1.5	-2.0	-1.3	1.6	-1.8	-2.4	1.5	-1.4	1.6	1.7	-2.1	-1.7	2.1	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.6	0.8	3.2	-0.8	-0.2	-0.8	-0.6	-0.5	-0.8	-0.8	-1.2	-0.8	0.7	-0.5	-1.0	0.7	-1.2	0.6	0.9	-0.5	-1.3	1.0	-1.8	-0.7	-0.8	-0.3	-1.5	-0.7
Coronary Artery Disease (CAD)	3.0	3.5	8.2	-1.8	-0.2	-2.3	-2.8	-2.3	-2.2	-2.1	-1.5	-2.3	2.4	-1.0	-0.5	2.2	-2.9	2.4	2.1	-2.0	-1.3	1.1	-1.6	-1.5	-1.6	-1.6	-0.6	-1.5
Crohns Disease (2012)	6.5	10.4	14.1	3.2	3.1	3.5	3.7	2.6	3.6	3.5	3.3	3.6	-3.1	2.6	2.1	-3.7	3.5	-2.2	-3.3	2.3	3.7	-2.7	3.8	3.4	3.4	3.7	2.7	3.4
Mean Putamen Volume	10.8	12.3	17.7	-3.7	-3.4	-3.7	-3.4	-2.7	-3.7	-3.6	-3.9	-3.6	3.6	-3.4	-2.6	3.6	-3.1	3.2	3.7	-3.3	-3.5	3.1	-4.2	-3.9	-3.8	-3.8	-2.8	-3.9
Fasting Glucose	1.5	1.8	3.4	1.1	0.6	1.7	1.2	1.5	1.7	1.7	0.5	1.7	-1.7	1.1	0.2	-1.6	1.1	-1.7	-1.4	1.0	1.2	-0.9	1.3	1.8	1.7	1.3	0.5	1.8
HbA1C	0.7	0.7	1.6	-0.7	-1.2	-1.0	-1.2	-0.8	-1.0	-1.1	-0.9	-1.2	0.9	-0.9	0.0	1.0	-0.8	0.4	1.0	-0.8	-0.6	0.4	-0.6	-0.9	-0.8	-0.0	-1.1	-0.9
HDL Cholesterol	0.2	0.3	1.4	0.1	-0.2	-0.4	-0.8	-0.4	-0.4	-0.5	0.2	-0.8	0.9	-0.4	0.9	0.4	-0.2	1.2	0.3	-0.1	0.5	-0.4	-0.8	-0.4	-0.3	0.5	-0.1	-0.3
LDL Cholesterol	3.7	5.8	10.9	-2.3	-2.5	-2.4	-2.4	-1.9	-2.4	-2.5	-2.7	-2.5	2.4	-2.7	-2.1	2.5	-1.6	2.0	2.5	-2.1	-2.4	2.3	-1.4	-2.7	-2.6	-3.3	-2.3	-2.8
Lupus	6.8	10.2	13.9	3.5	3.3	3.5	3.1	2.4	3.4	3.5	3.6	3.4	-3.7	3.5	2.6	-3.4	3.0	-3.7	-3.5	2.9	3.4	-3.1	3.3	2.9	3.0	3.0	1.5	2.9
Neuroticism (2016)	20.7	29.9	38.9	-5.8	-4.8	-6.1	-5.8	-5.7	-6.2	-6.2	-5.8	-5.6	6.0	-5.3	-5.3	6.2	-5.9	6.2	5.9	-5.7	-5.8	5.8	-3.3	-4.7	-4.9	-4.7	-3.2	-4.4
Primary Biliary Cirrhosis	11.7	16.6	21.1	4.1	3.1	4.5	4.1	3.9	4.5	4.5	3.9	4.6	-4.5	4.0	2.8	-4.5	4.0	-4.0	-4.5	4.2	3.8	-3.7	3.9	4.3	4.2	4.1	3.3	4.2
Rheumatoid Arthritis	1.0	1.4	2.7	-1.2	-0.8	-1.0	-0.5	-1.2	-1.0	-1.0	-1.5	-1.1	1.3	-1.5	-1.6	1.0	-0.9	1.6	1.2	-1.1	-1.4	1.4	-0.6	-1.2	-1.1	-1.0	-0.7	-1.1
Schizophrenia (2014)	4.2	9.2	16.7	2.8	3.2	3.5	4.1	1.7	3.4	3.5	3.1	3.5	-3.1	2.4	1.1	-3.4	3.3	-2.3	-3.1	1.9	3.2	-2.0	2.9	3.4	3.5	3.6	2.4	3.4
Triglycerides	0.6	0.9	1.8	0.7	0.7	1.0	1.0	0.8	1.0	1.0	0.7	1.2	-1.3	1.0	0.2	-1.0	0.7	-1.4	-0.9	0.9	0.3	-0.6	1.0	1.3	1.3	1.1	-0.4	1.2
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.2	1.3	0.6	0.9	1.3	1.3	1.1	1.5	1.2	1.0	-1.4	0.8	0.8	-1.2	1.4	-1.6	-1.3	1.8	0.8	-1.0	1.7	0.9	1.1	1.1	0.5	1.0
Ulcerative Colitis	0.8	1.2	3.0	1.0	0.5	1.3	1.1	0.9	1.3	1.3	1.1	1.2	-1.0	0.3	0.1	-1.2	1.7	-0.7	-1.2	0.7	1.2	-0.6	1.5	1.1	1.1	1.3	1.3	0.9
Blood Eosinophil Count	15.6	120.0	141.6	11.2	9.4	11.8	9.7	10.6	11.8	11.8	11.1	11.7	-11.4	10.9	9.0	-11.8	10.3	-9.9	-11.7	10.3	11.3	-10.6	9.0	11.9	11.9	11.5	10.4	11.9
Blood Platelet Count	1.7	19.7	37.0	-4.1	-1.9	-5.0	-4.8	-5.5	-5.0	-4.9	-3.1	-5.0	5.4	-3.5	-2.1	5.0	-6.1	5.8	4.9	-4.0	-3.7	3.6	-5.6	-4.5	-4.4	-1.7	-3.3	-4.2
Blood Red Count	41.6	401.7	475.2	-21.0	-17.1	-21.8	-18.2	-19.6	-21.8	-21.8	-20.2	-21.8	21.6	-20.4	-16.3	21.8	-18.9	19.4	21.7	-20.0	-20.0	19.6	-18.6	-21.1	-21.0	-18.1	-16.5	-21.0
Blood White Count	3.2	24.0	48.4	-5.0	-3.7	-5.3	-5.0	-4.8	-5.4	-5.3	-5.1	-5.5	6.1	-4.9	-3.6	5.4	-5.5	7.0	5.4	-4.6	-4.8	4.6	-5.0	-4.2	-4.0	-2.5	-3.2	-4.0
Heel T-Score	12.2	97.1	139.2	10.1	8.9	10.5	9.9	8.8	10.5	10.5	11.8	10.4	-10.8	9.1	8.4	-10.5	10.4	-10.5	-10.6	9.3	10.5	-9.2	9.2	9.3	9.3	9.8	7.9	9.3
BMI	0.7	3.9	9.2	-1.6	-1.8	-2.4	-2.7	-1.0	-2.4	-2.4	-2.2	-2.3	2.3	-1.3	-0.3	2.5	-3.0	2.2	2.2	-0.8	-2.5	1.2	-2.2	-1.4	-1.5	-0.8	-2.2	-1.4
Height	5.1	98.5	139.2	10.8	8.6	10.5	8.4	10.7	10.6	10.5	10.3	10.2	-10.4	9.6	8.4	-10.6	9.0	-9.1	-10.6	10.8	9.1	-9.5	8.6	9.9	9.9	11.8	9.4	9.9
Waist Hip Ratio (WHR)	16.4	73.7	102.0	-8.8	-5.2	-9.6	-8.2	-9.3	-9.6	-9.5	-8.0	-9.3	9.5	-7.1	-5.3	9.6	-10.1	8.7	9.6	-8.5	-8.1	7.5	-8.4	-8.9	-8.9	-7.2	-8.7	-8.9
Systolic Blood Pressure	7.4	37.1	61.6	6.5	6.2	6.3	6.0	5.5	6.3	6.3	7.8	6.2	-6.4	5.8	6.1	-6.3	5.9	-5.9	-6.4	6.2	6.5	-6.0	7.2	4.8	4.8	6.8	3.7	4.7
Smoking Status	5.4	13.0	18.5	4.0	3.7	3.6	2.5	3.6	3.5	3.6	3.8	3.6	-3.6	4.3	4.1	-3.5	2.3	-3.2	-3.6	4.0	3.6	-4.1	4.1	3.9	3.8	3.8	1.7	3.8
Allergy or Eczema	0.7	1.9	15.4	1.5	1.3	1.2	1.1	1.5	1.2	1.2	1.0	1.3	-0.9	1.0	1.1	-1.1	0.7	-0.3	-1.1	1.4	0.9	-1.0	3.9	1.5	1.4	0.5	0.8	1.4
Cardiovascular Disease	0.7	2.4	5.2	1.9	1.8	1.4	1.6	1.3	1.4	1.4	2.2	1.4	-1.4	1.4	2.0	-1.4	1.4	-1.2	-1.5	1.6	1.9	-1.7	2.3	1.0	1.0	2.2	-0.0	0.9
Hypothyroidism (self reported)	2.0	4.7	9.4	-2.1	-1.5	-2.5	-3.0	-2.5	-2.5	-2.6	-2.1	-2.6	2.7	-1.5	-1.0	2.5	-3.1	2.7	2.4	-2.0	-2.0	1.5	-1.4	-1.8	-2.0	-1.4	-0.3	-1.9
Respiratory disease	0.4	0.9	11.8	0.7	0.5	0.5	1.0	1.0	0.5	0.4	0.9	0.5	-0.3	-0.5	0.4	-0.5	1.4	-0.1	-0.4	-0.2	0.8	-0.0	3.4	0.6	0.4	0.5	0.9	0.5
Type 2 Diabetes (T2D) (2018)	0.8	1.5	2.4	-1.3	-0.8	-1.4	-1.3	-1.0	-1.4	-1.4	-1.3	-1.3	1.4	-1.2	-1.0	1.4	-1.6	1.3	1.5	-1.3	-1.5	1.3	0.3	-0.7	-0.8	-0.6	-1.3	-0.8
Lung FEV1/FVC ratio	3.6	18.0	23.9	4.6	4.4	4.8	4.1	4.4	4.7	4.8	4.3	4.9	-4.4	4.8	3.8	-4.7	3.1	-3.3	-4.6	4.8	4.1	-4.3	2.4	4.4	4.4	3.5	3.0	4.3
Lung FVC	40.5	205.9	243.4	14.9	12.8	15.3	13.6	13.6	15.3	15.3	15.5	15.1	-15.5	13.7	11.6	-15.3	14.5	-14.5	-15.3	13.5	14.8	-13.5	13.1	14.7	14.6	15.6	11.5	14.5
Neuroticism	40.5	97.7	118.8	-10.5	-7.7	-10.7	-8.4	-10.0	-10.7	-10.7	-10.6	-10.5	10.7	-9.8	-8.6	10.7	-9.7	9.8	10.9	-10.2	-10.1	9.9	-7.3	-10.0	-10.1	-10.3	-8.1	-10.0
Chronotype (morning person)	0.9	2.2	5.1	-1.3	-0.3	-1.6	-1.4	-1.3	-1.6	-1.6	-1.4	-1.6	1.7	-1.1	-0.6	1.6	-1.8	1.8	1.7	-1.6	-1.2	1.2	-1.6	-1.5	-1.4	-0.5	-2.3	-1.5
Hair Pigment	0.6	17.8	24.4	4.2	3.2	4.6	3.9	4.7	4.6	4.6	3.7	4.6	-4.4	3.8	3.0	-4.6	4.1	-3.7	-4.5	4.2	3.7	-3.7	4.0	4.9	4.8	3.2	4.9	4.8
Tanning	0.9	10.5	15.3	3.1	2.5	3.5	3.5	2.6	3.5	3.5	3.5	3.6	-3.8	3.1	2.0	-3.4	3.3	-3.9	-3.6	3.2	3.0	-2.8	2.1	3.5	3.6	3.2	2.7	3.4
Hand grip strength (left)	16.0	42.2	51.9	6.7	6.3	7.0	6.4	6.6	7.0	7.1	6.5	7.0	-7.2	6.5	4.9	-6.9	6.2	-6.8	-6.8	6.3	6.0	-5.9	6.0	6.8	6.8	6.8	4.6	6.7
Number of treatments/medications taken	1.2	2.2	3.7	-1.5	-1.1	-1.8	-1.9	-1.3	-1.8	-1.9	-1.2	-1.8	1.9	-1.6	-0.8	1.8	-1.6	1.9	1.8	-1.8	-1.3	1.5	0.5	-1.2	-1.3	-0.6	0.8	-1.2
Average weekly spirits intake	0.2	0.3	1.3	-0.1	0.3	-0.6	-0.7	-1.1	-0.6	-0.6	-0.1	-0.6	0.6	0.3	0.6	0.6	-1.2	0.7	0.5	-0.1	0.2	-0.3	-0.7	-0.3	-0.3	0.3	-0.0	-0.2
Sensitivity / hurt feelings	45.8	78.4	95.5	-9.4	-8.2	-9.5	-8.1	-8.5	-9.5	-9.5	-9.8	-9.5	9.5	-9.3	-8.1	9.5	-7.9	8.8	9.5	-9.0	-9.1	9.0	-7.9	-8.6	-8.6	-8.9	-6.3	-8.5
Frequency of depressed mood in last 2 weeks	10.6	14.8	21.1	-4.1	-3.0	-4.0	-2.5	-3.6	-3.9	-4.0	-4.6	-4.0	4.0	-4.3	-4.0	3.9	-3.2	3.7	4.2	-4.0	-4.3	4.2	-1.9	-3.9	-4.1	-4.4	-3.2	-4.0
Hearing difficulty/problems: Yes	6.6	10.1	17.4	-3.7	-3.0	-3.3	-3.0	-3.1	-3.4	-3.3	-4.2	-3.2	3.3	-2.8	-3.3	3.4	-3.6	3.1	3.4	-3.0	-3.8	3.2	-3.5	-2.5	-2.3	-3.3	-1.3	-2.5
Relative age of first facial hair	48.2	99.1	123.2	-10.4	-8.3	-11.1	-9.1	-10.2	-11.0	-11.1	-10.1	-11.0	10.9	-9.9	-7.3	11.0	-9.4	9.5	10.9	-10.0	-9.4	9.1	-9.6	-10.3	-10.4	-9.9	-7.3	-10.4
Other serious medical condition/disability diagnosed by doctor	2.5	3.2	7.1	-1.8	-1.4	-2.0	-2.1	-1.7	-2.0	-2.0	-2.2	-2.1	2.3	-1.6	-1.0	1.9	-2.2	2.7	2.0	-1.6	-1.6	1.3	0.2	-1.6	-1.5	-1.8	-0.8	-1.6
Ever used hormone-replacement therapy (HRT)	1.0	1.3	2.8	-1.1	-0.7	-1.2	-1.4	-1.0	-1.2	-1.2	-1.4	-1.3	1.4	-1.0	-1.2	1.1	-1.7	1.7	1.3	-1.1	-1.6	1.3	0.0	-0.2	-0.1	-0.2	1.2	-0.2
Ever had hysterectomy (womb removed)	0.9	1.0	2.9	-0.7	-0.0	-1.1	-1.6	-1.2	-1.1	-1.2	-0.6	-1.3	1.1	-0.2	0.1	1.1	-1.7	1.0	1.0	-0.5	-0.8	0.3	-1.2	-1.2	-1.1	-0.7	-0.1	-1.2
Systolic blood pressure, automated reading	10.0	29.0	42.7	6.0	5.1	5.7	4.3	5.5	5.7	5.7	6.5	5.6	-5.5	5.5	5.4	-5.7	4.4	-4.5	-5.8	5.9	5.4	-5.4	6.1	4.8	4.9	6.0	3.1	4.8
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.3	0.5	0.4	0.3	-0.3	0.8	0.3	0.2	0.0	0.4	-0.2	0.7	0.7	-0.3	-0.5	0.1	-0.2	0.6	0.1	-0.6	0.0	0.4	0.5	0.1	-1.2	0.5
Angina	0.1	0.1	1.0	-0.1	-0.2	-0.1	-0.4	0.1	-0.1	-0.1	-0.1	-0.0	0.1	0.2	0.3	0.1	-0.1	0.0	0.1	-0.1	0.2	-0.3	0.1	-0.2	-0.0	0.2	-1.0	-0.2
Medication for hormone replacement therapy	3.6	4.0	10.9	2.0	2.8	2.0	2.1	1.4	2.0	2.0	1.9	1.9	-1.9	2.1	1.6	-2.0	1.4	-1.7	-1.8	1.7	1.8	-1.8	1.4	2.2	2.2	2.1	3.3	2.2
Vitamin and mineral supplements	8.5	11.5	16.9	3.2	1.3	4.0	2.8	3.5	4.0	4.0	3.0	4.1	-3.9	3.2	1.8	-4.0	3.9	-3.4	-4.1	3.4	3.4	-3.1	2.4	3.6	3.7	3.4	2.2	3.6
Supplements: Zinc	4.2	4.6	6.5	-2.0	-1.2	-2.5	-2.1	-2.1	-2.5	-2.5	-1.9	-2.5	2.3	-1.9	-1.2	2.4	-2.3	1.8	2.5	-2.2	-2.1	2.0	-1.6	-2.5	-2.4	-2.5	-1.3	-2.4
Medication: Co-codamol	0.4	0.5	2.6	-0.6	0.5	-0.6	0.0	-0.7	-0.6	-0.6	-0.6	-0.4	0.5	-0.2	-0.6	0.6	-1.1	0.7	0.7	-0.3	-1.0	0.7	0.6	-0.7	-0.7	-0.2	-1.6	-0.7
Medication: Metformin	0.4	0.6	2.6	-0.6	-0.4	-0.8	-0.9	-0.8	-0.8	-0.8	-0.4	-0.8	0.8	-0.6	-0.4	0.8	-1.0	0.9	0.7	-0.6	-0.7	0.7	-0.4	-0.5	-0.7	-0.0	-1.6	-0.7
Diabetes (father)	2.2	2.7	5.8	-1.3	-1.9	-1.6	-1.4	-1.1	-1.5	-1.6	-1.3	-1.7	1.3	-1.7	-1.1	1.5	-0.9	0.8	1.4	-1.0	-1.5	1.3	-2.1	-2.3	-2.3	-2.1	-2.4	-2.3
Diabetes (mother)	0.1	0.2	1.0	0.3	-0.6	-0.2	-0.6	0.3	-0.2	-0.1	0.3	-0.2	-0.3	0.2	0.6	0.2	0.1	-1.0	-0.1	0.5	-0.0	-0.4	0.2	0.3	0.2	0.3	-0.7	0.3
Severe depression (siblings)	2.9	3.3	7.0	-1.9	-0.9	-1.6	-0.9	-2.4	-1.6	-1.5	-1.1	-1.6	1.6	-1.8	-1.8	1.6	-1.1	1.5	1.6	-2.1	-1.1	1.9	-1.9	-2.5	-2.5	-2.6	-1.7	-2.6
Pack years adult smoking proportion	1.3	2.1	4.3	-1.5	-1.3	-1.4	-1.2	-1.7	-1.5	-1.4	-1.6	-1.5	1.5	-1.6	-2.1	1.5	-1.4	1.6	1.5	-1.5	-1.7	1.9	-0.5	-0.8	-0.8	-0.3	-1.8	-0.9
Impedance of leg (right)	3.5	17.1	26.7	3.8	4.8	4.6	5.0	2.9	4.6	4.6	4.6	4.6	-4.4	3.8	2.3	-4.7	4.0	-3.5	-4.2	3.1	4.3	-3.1	5.2	4.2	4.1	4.1	3.6	4.1
Leg fat-free mass (left)	0.1	0.7	4.2	1.0	-0.2	0.0	-1.0	1.6	-0.0	0.0	0.3	-0.0	-0.1	0.9	2.1	0.0	-0.6	-0.1	-0.4	1.8	-0.1	-1.4	-0.4	0.2	0.2	1.4	-0.5	0.2
Trunk fat percentage	7.0	28.2	49.2	5.8	4.9	5.4	4.0	5.3	5.4	5.4	5.8	5.3	-5.1	5.6	5.4	-5.3	3.9	-4.1	-5.5	5.9	5.2	-5.5	5.3	5.6	5.6	7.0	3.9	5.7
Hand grip strength (right)	12.4	33.8	41.1	6.0	5.5	6.3	6.4	6.0	6.3	6.3	5.8	6.2	-6.4	5.2	4.1	-6.2	6.1	-6.0	-6.1	5.6	5.3	-5.0	5.3	5.9	5.9	6.4	4.3	5.9
Townsend deprivation index at recruitment	0.3	0.4	2.7	-0.4	-0.0	-0.4	-1.3	-0.5	-0.4	-0.4	-0.5	-0.4	0.6	0.3	-0.2	0.4	-1.6	1.2	0.3	-0.1	-0.6	0.1	-0.3	-0.4	-0.4	-0.3	-0.6	-0.4
Current tobacco smoking	1.3	2.1	3.7	1.6	1.6	1.5	1.0	1.2	1.4	1.5	1.5	1.5	-1.3	1.8	1.5	-1.4	0.7	-0.8	-1.4	1.5	1.5	-1.5	1.9	1.7	1.6	1.6	0.8	1.6
Average weekly fortified wine intake	4.0	4.7	6.4	2.3	2.2	2.2	2.2	2.5	2.2	2.2	2.0	2.3	-2.2	2.1	2.0	-2.2	2.1	-2.1	-2.1	1.9	2.2	-2.0	2.5	2.4	2.4	1.0	2.3	2.3
Maternal smoking around birth	0.1	0.1	0.8	-0.0	0.2	0.0	-0.5	-0.3	0.0	-0.0	-0.1	0.1	0.2	0.6	0.2	-0.0	-0.9	0.6	-0.0	0.1	-0.1	-0.3	0.4	-0.0	0.1	0.7	-0.0	0.1
Fed-up feelings	19.3	35.1	46.1	-6.0	-4.1	-6.7	-5.4	-6.0	-6.7	-6.7	-6.2	-6.8	6.4	-5.8	-4.6	6.6	-5.8	5.4	6.7	-6.1	-5.9	5.6	-4.9	-6.0	-6.2	-5.7	-4.7	-6.2
Frequency of unenthusiasm / disinterest in last 2 weeks	3.2	4.2	8.8	-2.0	-1.1	-2.0	-0.9	-1.7	-2.0	-2.0	-2.5	-2.1	2.1	-2.4	-2.3	2.0	-1.5	2.0	2.3	-2.1	-2.5	2.4	-0.7	-1.9	-2.0	-2.2	-3.0	-2.0
Relative age voice broke	30.3	46.3	55.9	-7.0	-5.9	-7.4	-5.9	-6.6	-7.4	-7.4	-7.1	-7.3	7.5	-6.8	-5.1	7.4	-6.4	6.9	7.4	-6.5	-6.6	6.3	-6.5	-7.2	-7.3	-6.4	-5.9	-7.2
Taking other prescription medications	0.5	0.8	1.9	-0.7	-0.8	-1.1	-1.4	-0.6	-1.1	-1.1	-1.1	-1.1	1.2	-0.7	-0.1	1.1	-1.1	1.1	1.1	-0.8	-0.7	0.4	0.8	-0.3	-0.4	-0.4	0.4	-0.3
Age when periods started (menarche)	6.0	14.4	19.7	-4.1	-3.1	-4.1	-3.9	-3.7	-4.1	-4.1	-4.2	-4.0	4.0	-3.4	-3.6	4.1	-4.4	3.7	4.1	-3.7	-4.4	3.9	-3.5	-3.4	-3.5	-3.3	-2.3	-3.4
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	3.6	-1.1	-1.1	-1.4	-1.6	-0.9	-1.4	-1.5	-1.5	-1.6	1.5	-1.4	-0.9	1.4	-1.3	1.6	1.4	-0.9	-1.5	1.1	-1.9	-1.1	-1.1	-1.2	0.7	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	6.1	13.9	21.9	4.0	3.7	3.8	3.9	3.2	3.8	3.9	4.7	3.7	-4.1	3.4	3.7	-3.8	4.2	-4.4	-3.9	3.8	4.3	-3.8	3.0	2.9	3.1	3.7	2.6	3.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	0.5	0.1	0.3	-0.1	0.2	0.3	0.3	0.6	0.3	-0.5	0.6	0.6	-0.4	0.5	-0.9	-0.5	0.2	0.7	-0.6	0.4	0.2	0.2	-0.1	0.1	0.1
Qualifications: CSEs or equivalent	7.2	9.5	15.6	-2.9	-1.8	-3.2	-2.5	-3.0	-3.3	-3.2	-2.6	-3.3	3.2	-2.7	-1.6	3.3	-3.0	2.7	3.2	-2.8	-2.7	2.4	-3.5	-3.9	-3.9	-3.0	-4.0	-3.9
Serious illness, injury or assault to yourself	1.0	1.2	3.5	-0.9	-1.4	-1.1	-1.9	-0.1	-1.1	-1.2	-1.6	-1.1	1.1	-0.6	-0.3	1.1	-1.1	1.0	1.0	-0.7	-1.0	0.4	-0.9	-1.1	-1.1	-1.8	-1.1	-1.1
High blood pressure	5.0	13.9	20.5	4.1	3.4	3.8	3.3	3.5	3.7	3.7	4.3	3.7	-3.7	3.6	3.7	-3.7	3.5	-3.4	-3.9	3.9	3.9	-3.8	4.2	3.7	3.8	4.5	2.1	3.6
Hayfever, allergic rhinitis or eczema	0.3	0.7	10.5	0.6	0.7	0.4	0.3	0.8	0.4	0.4	0.2	0.5	-0.1	0.3	0.5	-0.3	-0.2	0.6	-0.3	0.7	0.2	-0.3	3.2	0.8	0.8	-0.1	-0.4	0.7
Multivitamins +/- minerals	4.0	5.0	8.2	-1.9	-0.9	-2.8	-1.8	-2.2	-2.8	-2.8	-1.9	-2.9	2.7	-2.3	-1.1	2.8	-2.6	2.4	2.8	-2.0	-2.4	2.1	-1.5	-2.3	-2.3	-1.9	-1.1	-2.3
Stomach or abdominal pain in last month	1.8	2.3	3.6	-1.6	-1.8	-1.6	-1.3	-1.1	-1.6	-1.6	-1.9	-1.7	1.5	-1.8	-1.7	1.6	-0.6	1.1	1.6	-1.7	-1.5	1.6	-0.7	-1.6	-1.7	-1.5	-1.2	-1.6
Supplements: Glucosamine	0.1	0.2	1.0	-0.0	-0.2	-0.6	-1.0	0.0	-0.6	-0.6	0.0	-0.7	0.4	-0.0	0.7	0.6	-0.7	0.2	0.4	0.1	-0.5	-0.1	0.2	-0.1	-0.1	-0.2	-0.2	-0.1
Diverticular disease/diverticulitis (self-reported)	6.9	8.2	12.0	3.1	3.1	2.6	1.8	2.7	2.6	2.6	3.0	2.6	-2.3	3.0	3.4	-2.6	1.7	-1.7	-2.6	2.7	2.9	-3.0	3.5	3.4	3.4	3.4	3.2	3.3
Medication: Atenolol	1.4	1.7	5.0	1.1	1.7	1.1	0.8	0.6	1.1	1.0	1.4	1.2	-1.0	1.6	1.4	-1.1	0.3	-0.8	-1.0	1.0	1.4	-1.3	1.8	1.6	1.7	2.2	1.0	1.7
Medication: Levothyroxine sodium	3.6	6.1	8.7	-2.7	-2.3	-2.8	-2.9	-2.8	-2.7	-2.8	-2.4	-2.9	2.8	-2.3	-2.0	2.7	-2.8	2.6	2.6	-2.4	-2.4	2.3	-2.0	-2.3	-2.3	-2.1	-0.3	-2.3
Sitting height	15.1	107.1	136.9	11.3	8.3	11.2	9.4	11.7	11.2	11.2	10.7	11.0	-11.2	9.8	8.8	-11.2	10.6	-10.2	-11.3	11.2	9.9	-10.0	9.1	9.9	9.9	10.5	8.2	9.9
Chronic bronchitis/emphysema (father)	0.2	0.2	1.7	0.3	0.4	0.3	0.1	0.4	0.3	0.3	0.0	0.3	-0.3	0.6	0.4	-0.3	-0.2	-0.2	-0.2	0.7	-0.1	-0.5	1.3	0.3	0.3	0.2	0.6	0.4
High blood pressure (mother)	3.9	5.5	11.2	2.9	1.9	2.3	1.0	2.9	2.4	2.4	2.6	2.2	-2.2	2.7	3.4	-2.4	1.9	-1.8	-2.5	2.8	2.7	-3.1	1.9	1.8	1.8	2.1	1.9	1.7
Body mass index (BMI)	0.3	1.3	4.4	-0.6	-1.4	-1.2	-2.1	-0.3	-1.3	-1.3	-1.1	-1.3	1.4	-0.4	0.3	1.3	-1.9	1.6	1.0	0.1	-1.4	0.2	-1.2	-0.6	-0.5	-0.0	-1.6	-0.5
Impedance of leg (left)	4.1	20.1	29.1	4.1	5.2	5.0	5.4	3.2	5.0	5.0	4.8	5.0	-4.7	4.0	2.3	-5.0	4.5	-3.9	-4.6	3.3	4.7	-3.2	5.1	4.7	4.6	4.4	4.2	4.7
Leg predicted mass (left)	0.1	0.8	4.6	1.1	-0.1	0.1	-0.9	1.6	0.1	0.1	0.4	0.0	-0.1	1.0	2.1	-0.0	-0.6	-0.1	-0.4	1.9	0.0	-1.5	-0.3	0.2	0.2	1.4	-0.5	0.3
Trunk fat mass	4.5	19.2	36.0	4.9	3.7	4.3	2.9	4.7	4.3	4.3	4.7	4.3	-4.1	4.7	4.8	-4.3	3.0	-3.3	-4.5	5.2	4.1	-4.7	4.2	4.6	4.7	6.0	3.1	4.7
Waist circumference	1.2	4.2	12.1	-1.7	-1.8	-2.3	-3.0	-1.4	-2.4	-2.4	-1.9	-2.2	2.5	-1.1	-0.2	2.4	-3.5	2.8	2.1	-0.8	-2.3	1.2	-1.8	-1.7	-1.6	-0.4	-2.5	-1.6
Number of incorrect matches in round	3.8	6.3	11.9	-2.7	-2.8	-2.4	-3.0	-2.6	-2.4	-2.4	-3.0	-2.3	2.9	-1.7	-1.9	2.4	-3.2	3.5	2.4	-2.1	-2.2	1.8	-2.2	-2.3	-2.3	-3.2	-2.2	-2.2
Past tobacco smoking	6.7	12.4	15.4	-3.8	-3.5	-3.6	-3.3	-3.4	-3.6	-3.6	-3.8	-3.7	3.8	-3.8	-3.6	3.6	-3.3	3.9	3.6	-3.4	-3.8	3.7	-3.0	-3.4	-3.3	-3.4	-1.9	-3.3
Alcohol usually taken with meals	1.4	2.3	4.9	1.5	0.9	1.4	1.7	1.5	1.4	1.4	1.8	1.4	-1.4	1.0	1.6	-1.4	1.9	-1.4	-1.5	1.6	1.6	-1.6	1.1	1.6	1.6	1.3	2.2	1.5
Nervous feelings	18.7	34.9	44.6	-6.6	-5.9	-6.4	-5.0	-5.8	-6.4	-6.4	-6.7	-6.3	6.3	-6.3	-5.5	6.4	-5.3	5.5	6.4	-6.0	-6.2	6.0	-3.6	-5.6	-5.9	-6.1	-4.6	-5.7
Frequency of tenseness / restlessness in last 2 weeks	25.6	39.8	52.4	-6.6	-4.9	-6.8	-5.2	-5.8	-6.8	-6.8	-6.9	-6.8	6.6	-6.5	-5.5	6.7	-6.0	5.9	7.0	-6.2	-6.8	6.3	-4.4	-6.3	-6.5	-7.2	-5.7	-6.4
Hearing difficulty/problems with background noise	12.1	19.3	28.7	-4.7	-3.9	-4.6	-3.8	-3.9	-4.6	-4.6	-5.4	-4.4	4.6	-4.2	-4.3	4.6	-4.5	4.4	4.7	-4.0	-5.0	4.5	-4.4	-3.9	-3.9	-4.3	-4.3	-3.9
Hair/balding pattern: Pattern 2	18.2	23.1	37.7	-4.4	-4.0	-4.8	-4.6	-3.6	-4.8	-4.8	-5.0	-4.8	4.7	-4.2	-3.3	4.8	-4.3	4.2	4.8	-4.1	-4.7	4.0	-4.8	-6.1	-6.1	-5.7	-5.9	-6.1
Had menopause	0.1	0.1	0.5	-0.1	-0.7	0.1	-0.7	0.6	0.2	0.1	-0.3	0.2	-0.1	0.0	-0.4	-0.2	0.1	-0.0	-0.2	-0.1	-0.3	0.2	0.2	0.5	0.6	0.1	0.5	0.6
Had other major operations	0.1	0.2	0.9	-0.1	-0.0	-0.1	-0.6	0.1	-0.1	-0.1	-0.5	-0.1	0.3	0.2	-0.4	0.1	-1.0	0.8	0.2	0.1	-0.7	0.3	-0.1	-0.3	-0.3	-0.2	0.9	-0.3
Forced vital capacity (FVC)	34.0	130.8	169.0	12.1	10.7	11.9	10.6	11.1	11.9	12.0	12.4	11.7	-12.2	11.1	10.0	-11.9	11.0	-11.6	-12.0	11.2	11.5	-11.0	10.8	11.6	11.5	13.0	8.9	11.5
Heel bone mineral density (BMD) T-score, automated (right)	5.7	13.1	20.8	4.0	3.6	3.9	4.1	3.2	3.9	3.9	4.6	3.8	-4.1	3.5	3.4	-3.9	3.8	-4.1	-3.9	4.0	3.9	-3.6	2.4	2.5	2.6	3.3	2.2	2.5
Ever unenthusiastic/disinterested for a whole week	14.8	18.0	25.4	-4.5	-3.7	-4.4	-2.8	-3.9	-4.4	-4.4	-4.4	-4.4	4.5	-5.0	-4.3	4.4	-2.9	4.1	4.6	-4.9	-4.0	4.8	-3.5	-4.4	-4.4	-4.2	-3.7	-4.5
Qualifications: None of the above	2.9	6.1	10.5	-2.7	-2.4	-2.4	-1.9	-2.3	-2.4	-2.4	-3.2	-2.4	2.6	-2.7	-3.2	2.4	-2.1	2.8	2.6	-2.6	-2.9	3.0	-1.8	-2.0	-2.1	-3.1	-0.6	-1.9
Financial difficulties in last 2 years	5.4	7.2	9.2	-2.6	-1.5	-2.9	-2.4	-2.7	-2.9	-2.9	-2.9	-3.0	3.0	-2.3	-1.9	2.9	-2.9	3.0	3.0	-2.6	-2.6	2.3	-2.5	-3.0	-3.0	-2.7	-2.2	-2.9
Mouth/teeth dental problems	8.7	13.4	20.5	3.9	3.5	3.8	3.9	3.1	3.9	3.8	4.4	3.6	-4.0	3.1	3.3	-3.9	4.5	-4.2	-3.8	2.9	4.5	-3.6	3.7	3.4	3.3	3.2	1.9	3.3
Heart attack	0.3	0.3	1.2	-0.7	-1.0	-0.5	-0.3	0.1	-0.4	-0.5	-0.8	-0.4	0.3	-0.8	-0.7	0.3	0.0	0.1	0.5	-0.5	-0.7	0.7	-0.6	-0.7	-0.6	-1.1	-0.4	-0.6
Allergy	0.2	0.6	9.3	0.1	0.2	0.2	-0.0	-0.5	0.2	0.2	0.5	0.1	-0.5	0.8	0.4	-0.3	0.0	-1.1	-0.4	0.5	0.3	-0.6	-3.0	-0.1	-0.1	0.8	0.4	-0.0
Pain all over the body in last month	0.9	1.0	2.5	-1.2	-0.8	-0.9	-0.7	-1.2	-0.9	-0.9	-1.2	-0.8	1.1	-0.7	-1.2	0.9	-1.6	1.5	1.0	-0.7	-1.3	1.1	0.2	-0.6	-0.5	-1.0	-0.9	-0.4
Diabetes (self-reported)	0.0	0.1	0.4	-0.0	-0.2	-0.2	-0.4	-0.1	-0.2	-0.2	-0.1	-0.3	0.4	-0.2	0.2	0.2	-0.3	0.7	0.2	-0.0	-0.0	-0.0	0.4	0.2	0.1	0.3	-0.3	0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.8	-0.1	0.2	-0.2	-0.1	0.5	-0.2	-0.2	-0.4	-0.1	0.3	-0.1	0.1	0.3	-0.6	0.6	0.3	0.2	-0.6	0.2	0.7	-0.3	-0.3	-0.9	-0.9	-0.4
Medication: Ramipril	0.3	0.4	1.8	0.5	-0.1	0.6	1.0	-0.3	0.6	0.6	1.0	0.4	-0.8	-0.2	-0.4	-0.6	1.3	-0.9	-0.7	0.6	0.4	-0.1	0.7	0.5	0.6	1.2	0.2	0.5
Medication: Simvastatin	0.2	0.2	1.1	0.5	0.8	0.4	-0.2	-0.0	0.4	0.3	0.6	0.4	-0.1	1.1	0.9	-0.4	-0.6	0.3	-0.4	0.5	0.7	-0.8	-0.3	0.1	0.2	0.4	0.0	0.0
Fluid intelligence score	7.3	15.2	26.3	4.4	5.1	3.9	3.7	3.1	3.9	4.0	4.8	3.9	-4.2	4.5	4.4	-3.9	2.9	-4.2	-3.9	3.9	4.3	-4.3	2.9	3.2	3.2	3.7	3.1	3.1
Illnesses of siblings	0.4	0.5	1.1	-0.6	-1.0	-0.9	-0.4	-0.7	-0.9	-0.8	-0.7	-1.0	0.7	-0.9	-0.2	0.9	-0.1	0.1	0.7	-0.3	-0.6	0.3	-1.0	-0.8	-0.9	-0.3	-0.6	-0.9
Neuroticism score	35.6	74.2	90.8	-9.3	-6.6	-9.1	-6.9	-9.1	-9.2	-9.1	-9.5	-9.0	9.1	-8.6	-8.2	9.2	-8.3	8.5	9.5	-9.2	-8.9	8.9	-6.5	-8.4	-8.7	-8.8	-7.3	-8.6
Weight	0.6	3.0	8.6	2.2	1.0	1.3	-0.1	2.5	1.2	1.3	1.6	1.2	-1.2	2.1	2.9	-1.2	0.2	-0.7	-1.6	2.9	1.0	-2.4	1.0	1.7	1.8	2.9	0.9	1.8
Impedance of arm (right)	9.5	44.1	60.4	6.8	7.4	6.9	6.5	5.2	6.9	6.9	7.8	6.9	-6.9	6.6	5.7	-6.9	6.0	-6.4	-6.7	5.6	7.4	-6.2	7.3	6.4	6.3	7.7	5.4	6.4
Arm fat percentage (right)	0.9	3.5	12.0	2.2	1.8	1.4	0.5	1.8	1.4	1.4	2.1	1.4	-1.3	2.4	2.9	-1.4	0.3	-0.8	-1.6	2.4	1.8	-2.4	1.8	2.0	2.1	3.5	0.3	2.1
Trunk fat-free mass	0.3	1.7	5.2	-0.6	-1.7	-1.4	-2.1	0.3	-1.4	-1.4	-1.4	-1.4	1.3	-0.7	0.2	1.4	-1.8	1.2	1.1	0.4	-1.8	0.3	-2.3	-1.1	-1.1	-0.5	-1.4	-1.1
Hip circumference	1.5	6.3	14.2	3.0	1.4	2.4	0.9	3.5	2.4	2.4	2.4	2.4	-2.2	2.9	3.2	-2.3	1.2	-1.6	-2.7	3.8	1.8	-3.0	2.4	2.5	2.5	3.1	2.0	2.6
Time employed in main current job	10.8	12.5	19.5	3.3	1.9	3.9	3.0	3.3	3.9	3.9	3.6	3.8	-3.6	2.7	2.2	-4.0	3.9	-2.8	-3.9	3.2	3.6	-2.9	3.6	4.3	4.4	3.8	3.0	4.3
Alcohol intake versus 10 years previously	0.1	0.2	1.0	-0.5	-0.1	-0.4	-0.2	-1.0	-0.4	-0.5	-0.2	-0.4	0.4	-0.4	-0.0	0.4	0.1	0.0	0.5	-1.0	0.4	0.1	0.3	0.1	0.0	0.4	0.2	0.2
Father’s age at death	1.5	2.0	4.5	1.3	1.2	1.5	1.4	1.2	1.6	1.5	1.6	1.4	-1.5	1.1	1.1	-1.6	1.7	-1.3	-1.6	1.5	1.6	-1.4	1.0	1.4	1.3	1.0	2.1	1.4
Worrier / anxious feelings	14.4	27.2	34.0	-5.8	-4.3	-5.5	-4.1	-5.5	-5.5	-5.5	-5.8	-5.5	5.4	-5.4	-5.2	5.5	-4.6	4.9	5.7	-5.7	-5.3	5.5	-3.7	-5.1	-5.3	-5.5	-3.9	-5.2
Frequency of tiredness / lethargy in last 2 weeks	4.4	7.1	9.6	-2.8	-1.3	-2.9	-1.8	-2.7	-2.9	-2.9	-3.0	-2.9	2.8	-2.5	-2.3	2.9	-2.9	2.6	3.1	-2.7	-3.1	2.7	-1.3	-2.9	-3.0	-2.9	-1.7	-3.0
Falls in the last year	5.5	7.4	10.1	-2.7	-3.2	-3.0	-3.2	-2.2	-3.0	-3.0	-3.0	-3.0	2.9	-2.5	-1.7	3.0	-2.6	2.6	2.7	-2.2	-2.6	2.1	-2.2	-2.9	-2.9	-3.0	-2.4	-2.9
Hair/balding pattern: Pattern 3	50.2	74.8	94.9	8.7	7.2	9.1	7.5	8.1	9.1	9.1	9.1	9.2	-9.0	8.7	7.2	-9.1	7.5	-7.8	-9.1	8.6	8.4	-8.1	9.3	9.7	9.7	9.1	7.2	9.7
Number of live births	12.6	17.8	23.2	-4.6	-3.6	-4.3	-3.7	-4.3	-4.4	-4.3	-4.3	-4.4	4.5	-4.7	-4.4	4.4	-3.5	4.2	4.4	-4.8	-4.2	4.7	-4.2	-4.4	-4.4	-3.7	-1.8	-4.4
Forced expiratory volume in 1-second (FEV1)	35.8	120.7	148.8	11.7	10.4	11.6	10.4	10.7	11.5	11.6	12.0	11.4	-11.8	10.7	9.7	-11.5	10.6	-11.2	-11.6	10.9	11.1	-10.6	9.9	11.0	10.9	12.2	7.9	10.9
Pulse rate	0.5	0.9	2.6	0.8	0.1	1.0	0.5	1.3	1.0	1.0	0.0	0.9	-0.9	0.6	0.4	-1.0	1.6	-0.9	-1.0	0.6	1.0	-1.0	1.2	1.2	1.2	-0.0	1.2	1.1
Happiness	2.7	3.2	5.8	-1.9	-1.8	-1.9	-1.2	-1.5	-1.9	-1.9	-1.8	-1.9	2.0	-2.4	-1.8	1.9	-1.1	2.0	1.9	-2.0	-1.7	2.2	-1.1	-1.8	-1.9	-1.6	-1.4	-1.9
Noisy workplace	9.5	11.8	19.3	-3.9	-3.5	-3.7	-3.4	-3.1	-3.7	-3.6	-4.4	-3.5	3.7	-3.3	-3.3	3.7	-3.5	3.6	3.7	-3.5	-3.8	3.4	-2.7	-3.0	-2.9	-3.1	-2.3	-2.9
Qualifications: A levels/AS levels or equivalent	8.1	18.0	25.3	4.8	4.8	4.5	3.8	4.3	4.5	4.5	5.0	4.4	-4.4	4.7	4.7	-4.5	3.5	-4.0	-4.5	4.5	4.7	-4.7	2.9	3.5	3.5	4.1	2.5	3.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.8	0.0	0.4	0.0	0.0	-0.7	-0.0	0.1	0.5	0.1	-0.2	0.4	0.4	0.0	-0.0	-0.4	-0.1	-0.2	0.5	-0.3	0.4	0.1	0.2	0.3	-0.9	0.2
Mouth/teeth dental problems: Dentures	0.3	0.4	1.6	-0.4	-0.4	0.3	-0.1	0.4	0.3	0.3	-0.9	0.5	0.1	0.1	-1.2	-0.3	-0.7	1.1	-0.1	0.0	-0.9	0.7	0.2	0.9	0.9	0.5	1.3	0.9
Asthma	0.8	1.6	8.6	1.1	0.9	1.1	1.5	1.4	1.1	1.1	1.4	1.0	-1.0	-0.1	0.2	-1.0	2.4	-1.0	-1.0	-0.1	1.4	-0.1	2.9	0.8	0.7	0.4	2.0	0.7
Medication: Ibuprofen (e.g. Nurofen)	12.8	16.2	24.8	-4.3	-3.5	-4.4	-3.9	-3.6	-4.4	-4.3	-4.5	-4.3	4.7	-4.2	-3.5	4.4	-4.2	5.0	4.5	-4.0	-4.2	4.1	-2.6	-3.7	-3.7	-3.6	-2.4	-3.7
Medication: Cholesterol lowering	0.1	0.2	1.0	-0.5	-0.6	-0.4	-0.5	-0.7	-0.3	-0.4	-0.1	-0.4	0.5	-0.5	-0.6	0.3	0.0	0.4	0.3	-1.0	0.1	0.6	-0.4	-0.2	-0.1	0.5	-0.5	-0.3
Depression (self-reported)	3.6	4.3	7.1	-2.5	-1.3	-2.1	-1.0	-2.1	-2.1	-2.1	-2.5	-2.0	2.4	-2.3	-2.6	2.1	-2.3	2.7	2.4	-2.2	-2.4	2.6	-0.8	-1.5	-1.6	-1.5	-1.6	-1.5
Medication: Lansoprazole	4.7	5.3	7.3	2.4	1.4	2.6	2.4	2.1	2.6	2.6	2.4	2.6	-2.6	2.2	1.6	-2.7	2.7	-2.5	-2.7	2.4	2.5	-2.2	1.9	1.8	1.9	1.8	2.3	1.9
Prospective memory result	2.6	3.2	4.7	-1.7	-1.9	-1.8	-1.7	-1.7	-1.8	-1.8	-1.9	-1.8	1.9	-1.7	-1.5	1.8	-1.9	2.2	1.7	-1.1	-2.0	1.6	-1.7	-1.9	-1.9	-2.0	-1.9	-1.8
Lung cancer (father)	0.1	0.2	0.5	0.3	-0.0	0.6	0.6	0.4	0.6	0.6	0.2	0.6	-0.3	0.3	0.1	-0.6	0.5	0.1	-0.5	0.5	0.3	-0.4	-0.5	-0.0	0.2	0.4	0.7	-0.0
Illnesses of mother	0.1	0.1	0.5	0.0	0.5	0.2	0.4	-0.2	0.2	0.2	-0.4	0.2	-0.2	0.5	0.1	-0.2	-0.2	-0.1	-0.0	0.1	0.1	-0.4	-0.0	0.6	0.7	0.4	-0.1	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	32.9	104.9	127.7	10.8	9.6	10.8	9.9	10.0	10.8	10.8	11.0	10.7	-11.0	9.9	8.8	-10.8	10.2	-10.5	-10.8	10.0	10.4	-9.8	9.3	10.3	10.1	11.3	7.6	10.2
Pulse wave Arterial Stiffness index	0.6	0.6	1.3	0.9	0.2	0.8	0.1	1.1	0.8	0.8	0.5	0.8	-0.7	0.8	1.0	-0.7	0.8	-0.4	-0.9	0.9	1.0	-1.1	0.4	1.0	1.1	0.8	0.2	1.1
Impedance of arm (left)	11.2	51.7	67.7	7.3	8.0	7.6	7.5	5.8	7.6	7.6	8.2	7.6	-7.5	6.9	5.8	-7.6	7.0	-6.8	-7.3	6.1	7.9	-6.4	7.7	6.7	6.7	8.0	6.3	6.8
Arm fat mass (right)	0.7	2.7	8.8	2.0	1.2	1.2	-0.1	2.0	1.1	1.1	1.7	1.1	-1.0	2.1	2.9	-1.1	-0.0	-0.5	-1.4	2.6	1.2	-2.2	1.1	1.7	1.8	3.0	0.1	1.8
Trunk predicted mass	0.3	1.6	4.7	-0.6	-1.7	-1.3	-2.0	0.3	-1.3	-1.3	-1.4	-1.4	1.2	-0.6	0.2	1.3	-1.8	1.2	1.1	0.4	-1.8	0.3	-2.2	-1.0	-1.0	-0.5	-1.4	-1.0
Standing height	3.8	38.1	51.8	7.0	5.8	6.3	5.0	6.9	6.3	6.3	6.6	6.1	-6.3	6.2	6.4	-6.3	5.2	-5.6	-6.4	7.0	5.8	-6.4	5.6	5.7	5.7	7.2	5.7	5.7
Length of working week for main job	0.9	1.0	1.8	1.0	0.4	1.3	1.2	1.2	1.3	1.3	0.8	1.3	-1.3	0.8	-0.0	-1.3	1.1	-1.1	-1.2	1.2	0.5	-0.5	-0.4	0.8	1.0	0.9	-0.2	0.9
Exposure to tobacco smoke at home	0.3	0.4	2.3	-0.6	0.3	-0.4	0.1	-1.1	-0.4	-0.3	-0.5	-0.5	0.0	-0.6	-1.5	0.3	0.0	-0.5	0.5	-1.1	-0.6	1.0	-0.1	-0.2	-0.3	-0.8	0.2	-0.2
Breastfed as a baby	0.4	0.4	4.5	0.4	0.3	0.2	-0.3	0.1	0.1	0.1	0.6	0.1	-0.3	0.7	0.9	-0.1	-0.0	-0.7	-0.3	0.4	0.5	-0.8	-0.3	0.9	0.8	0.7	2.1	0.9
Tense / ‘highly strung’	7.1	11.8	18.5	-3.7	-2.4	-3.6	-2.6	-3.4	-3.6	-3.6	-4.3	-3.5	3.7	-3.4	-3.5	3.6	-3.7	3.7	3.9	-3.5	-4.0	3.6	-1.5	-3.2	-3.3	-3.7	-2.7	-3.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	2.3	-1.3	-0.5	-1.2	-1.0	-1.2	-1.2	-1.2	-1.0	-1.1	1.0	-0.8	-1.0	1.2	-1.1	0.6	1.2	-1.5	-1.0	1.2	-0.6	-1.0	-1.0	-0.3	-1.0	-1.1
Hair/balding pattern: Pattern 4	87.6	212.2	262.4	14.6	12.8	15.6	14.0	13.5	15.6	15.6	15.1	15.5	-15.3	13.6	10.9	-15.6	14.4	-13.7	-15.3	13.4	14.6	-13.1	14.8	16.2	16.1	15.0	12.3	16.1
Birth weight of first child	2.3	4.2	8.8	2.3	1.6	1.9	0.5	2.3	1.9	1.9	1.7	1.9	-2.1	3.0	2.6	-2.0	0.6	-2.0	-2.1	2.9	1.4	-2.7	2.3	2.0	2.1	2.5	0.4	1.9
Peak expiratory flow (PEF)	21.0	48.8	60.4	7.5	6.3	7.2	6.3	7.1	7.2	7.2	7.8	7.0	-7.5	6.7	6.6	-7.2	7.3	-7.4	-7.4	7.0	7.3	-7.0	5.8	7.0	7.0	7.0	5.5	6.9
Pulse wave reflection index	1.0	1.3	3.3	-1.0	-0.5	-1.3	-1.2	-1.2	-1.3	-1.2	-1.0	-1.3	1.5	-1.0	-0.5	1.3	-1.4	1.8	1.3	-1.0	-0.9	0.9	-1.1	-1.0	-0.9	-0.3	-1.3	-0.9
Ever highly irritable/argumentative for 2 days	5.2	6.3	9.1	-2.6	-1.8	-2.9	-1.6	-2.4	-3.0	-2.9	-2.9	-2.9	3.0	-2.6	-1.5	3.0	-2.4	2.6	3.0	-2.2	-2.6	2.2	-1.7	-2.5	-2.5	-2.5	-1.7	-2.5
Loud music exposure frequency	0.7	0.8	3.0	0.8	1.4	0.8	1.7	0.2	0.7	0.8	1.2	0.8	-1.0	0.5	0.4	-0.7	1.1	-1.2	-0.7	0.3	1.0	-0.3	0.9	0.7	0.7	1.2	-0.4	0.7
Qualifications: O levels/GCSEs or equivalent	5.5	8.7	16.9	3.4	4.1	2.9	2.3	2.9	2.9	2.9	3.5	2.8	-3.0	3.7	4.0	-2.9	2.0	-2.9	-2.9	3.0	3.4	-3.6	2.2	2.3	2.3	2.6	1.5	2.2
Mouth/teeth dental problems: Bleeding gums	3.9	5.0	11.4	-1.8	-2.1	-2.4	-2.5	-1.7	-2.4	-2.4	-2.4	-2.4	2.2	-1.6	-1.0	2.4	-2.4	1.6	2.2	-1.3	-2.3	1.4	-3.4	-2.7	-2.6	-2.7	-2.0	-2.7
Blood clot in the leg (DVT)	0.7	1.0	2.3	-1.1	-1.3	-1.0	-1.3	-0.4	-1.0	-1.0	-1.3	-0.8	1.1	-1.1	-1.1	0.9	-1.1	1.5	1.0	-0.8	-1.4	1.1	0.1	-0.5	-0.6	-0.3	-0.5	-0.5
Medication: Paracetamol	29.1	48.2	60.5	-7.5	-7.1	-7.7	-7.3	-6.7	-7.8	-7.7	-7.5	-7.6	7.6	-6.8	-5.6	7.8	-7.0	6.8	7.5	-6.9	-7.1	6.6	-4.9	-6.7	-6.8	-6.2	-4.4	-6.6
Headache pain in last month	32.9	56.5	68.5	-7.7	-6.3	-8.2	-7.5	-6.3	-8.2	-8.2	-8.3	-8.0	8.2	-6.9	-5.7	8.2	-7.9	7.7	8.2	-7.1	-7.9	7.0	-5.8	-7.9	-8.0	-7.4	-5.8	-7.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.8	-0.5	-0.1	-0.9	-0.6	-0.4	-0.9	-0.9	-0.9	-1.0	0.6	-0.5	-0.2	0.9	-0.8	0.2	0.9	-0.3	-1.1	0.4	-1.4	-1.0	-1.0	-1.9	-0.3	-0.9
Glaucoma (self-reported)	6.0	7.1	10.1	-3.0	-1.6	-2.8	-2.4	-2.7	-2.9	-2.9	-3.2	-2.8	2.8	-2.4	-2.6	2.9	-2.9	2.6	3.0	-3.2	-2.8	2.8	-2.3	-2.3	-2.4	-1.9	-2.5	-2.4
Gout (self-reported)	3.5	4.8	10.5	2.1	2.1	2.6	3.2	1.6	2.6	2.6	2.2	2.6	-2.8	1.9	0.6	-2.5	2.6	-2.9	-2.5	2.1	1.9	-1.4	1.7	2.1	2.1	1.0	0.7	2.0
Hypothyroidism/myxoedema (self-reported)	3.3	6.4	11.8	-2.5	-2.6	-2.8	-3.4	-2.4	-2.8	-2.8	-2.6	-2.8	3.1	-2.1	-1.4	2.7	-3.2	3.4	2.6	-2.1	-2.4	1.9	-1.8	-2.3	-2.4	-2.0	-0.2	-2.3
Medication: Amlodipine	3.4	4.8	8.4	2.0	0.8	2.5	1.9	2.5	2.4	2.4	2.0	2.6	-2.5	1.8	0.8	-2.4	2.3	-2.1	-2.5	2.1	1.6	-1.4	2.4	2.5	2.5	2.9	1.6	2.6
Medication: Ventolin 100micrograms inhaler	2.2	2.9	9.0	1.7	1.1	1.6	1.9	1.5	1.5	1.5	2.1	1.5	-1.7	0.7	1.1	-1.5	2.6	-2.1	-1.6	0.9	2.0	-1.1	3.0	1.4	1.3	1.0	2.5	1.3
Birth weight	0.1	0.2	2.4	0.2	0.7	-0.0	0.1	-0.7	-0.0	-0.0	0.6	-0.1	0.1	0.4	0.8	0.0	-0.1	-0.0	-0.0	-0.1	0.7	-0.6	0.5	0.1	0.1	0.5	-1.5	0.1
Chronic bronchitis/emphysema (mother)	5.5	6.4	11.5	-2.8	-3.4	-2.3	-1.8	-1.8	-2.3	-2.4	-2.9	-2.3	2.7	-3.4	-3.3	2.3	-1.7	3.2	2.4	-2.2	-3.1	3.3	-1.3	-2.2	-2.1	-2.5	-1.8	-2.2
High blood pressure (siblings)	6.4	9.3	12.4	3.4	3.5	3.4	2.6	3.0	3.4	3.4	3.5	3.4	-3.1	3.4	2.8	-3.5	2.2	-2.2	-3.2	2.9	3.2	-2.9	3.1	2.8	2.9	2.3	2.6	2.8
Forced vital capacity (FVC), Best measure	33.1	121.2	158.8	11.6	10.2	11.6	10.4	10.6	11.5	11.6	11.8	11.3	-11.7	10.6	9.4	-11.5	10.8	-11.1	-11.5	10.6	11.1	-10.5	10.6	11.2	11.1	12.6	8.4	11.1
Body fat percentage	3.4	13.4	27.7	4.0	3.3	3.6	2.4	3.6	3.6	3.6	4.0	3.6	-3.3	4.0	3.9	-3.5	2.2	-2.4	-3.7	4.2	3.4	-3.9	3.8	4.0	4.1	5.3	2.3	4.1
Leg fat percentage (right)	0.5	1.7	4.5	1.4	0.7	1.1	0.3	1.5	1.1	1.1	1.2	1.1	-0.8	1.5	1.6	-1.1	0.1	-0.1	-1.3	2.0	0.8	-1.4	1.6	1.7	1.8	2.1	0.1	1.8
Arm fat-free mass (right)	0.1	0.6	2.2	0.1	-1.1	-0.5	-1.4	1.1	-0.5	-0.5	-0.8	-0.5	0.6	-0.1	0.5	0.5	-1.1	0.9	0.2	1.1	-1.2	-0.2	-1.5	-0.2	-0.2	0.2	-0.7	-0.2
Exposure to tobacco smoke outside home	8.3	11.0	14.3	-3.6	-2.6	-3.7	-3.1	-3.8	-3.8	-3.7	-3.8	-3.7	3.6	-3.1	-2.9	3.8	-3.4	3.0	3.7	-3.6	-3.4	3.2	-2.5	-3.3	-3.2	-2.7	-1.8	-3.2
Comparative body size at age 10	1.7	4.6	8.1	-2.0	-1.9	-2.7	-2.4	-2.0	-2.7	-2.7	-1.3	-2.6	2.2	-1.7	-0.2	2.7	-2.2	1.2	2.3	-1.7	-1.8	1.4	-2.3	-2.4	-2.4	-1.0	-2.9	-2.4
Number of full brothers	9.2	11.5	15.4	-3.3	-2.4	-3.4	-3.2	-3.5	-3.5	-3.4	-3.9	-3.4	3.5	-2.8	-2.8	3.5	-3.7	3.5	3.5	-3.1	-3.4	2.9	-3.8	-3.6	-3.6	-3.9	-2.8	-3.7
Worry too long after embarrassment	11.7	19.7	25.1	-4.6	-3.5	-4.8	-3.9	-4.7	-4.7	-4.8	-5.0	-4.8	4.8	-4.2	-3.8	4.7	-4.6	4.6	4.9	-4.3	-4.7	4.2	-3.8	-4.1	-4.2	-4.7	-3.9	-4.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.0	-0.8	-0.4	-0.7	-0.4	-0.5	-0.7	-0.7	-0.6	-0.6	0.8	-0.9	-1.3	0.7	-0.9	1.0	0.8	-0.9	-1.0	1.4	1.4	-0.4	-0.6	-0.3	-0.8	-0.5
Wheeze or whistling in the chest in last year	3.2	5.6	7.8	-2.4	-2.8	-2.7	-2.7	-1.6	-2.7	-2.7	-2.4	-2.6	2.6	-2.6	-2.0	2.8	-2.1	2.4	2.5	-2.4	-2.6	2.6	-0.3	-2.3	-2.3	-2.5	-0.5	-2.3
Number of children fathered	1.1	1.2	2.6	-1.1	-1.6	-1.2	-1.1	-0.8	-1.2	-1.2	-1.3	-1.3	1.3	-1.6	-0.8	1.2	-0.4	1.2	1.2	-1.0	-1.1	0.9	-1.3	-1.0	-0.8	-1.1	0.0	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.2	-1.2	-1.4	-1.0	-0.6	-0.7	-1.0	-1.0	-1.3	-0.9	1.0	-1.3	-1.3	1.0	-0.6	1.0	1.0	-1.1	-1.1	1.3	-1.4	-0.7	-0.8	-1.3	-1.5	-0.6
Age at first live birth	6.2	10.9	15.9	3.4	2.5	3.3	2.6	2.5	3.3	3.3	3.8	3.4	-3.4	3.6	3.5	-3.3	2.9	-3.4	-3.5	3.2	3.9	-3.7	3.2	3.3	3.4	4.0	2.2	3.4
Pulse wave peak to peak time	0.1	0.1	0.3	-0.1	0.3	-0.1	0.4	-0.4	-0.1	-0.2	0.2	-0.1	-0.0	-0.2	-0.3	0.1	-0.2	-0.2	0.2	-0.1	-0.3	0.4	0.2	-0.4	-0.6	-0.1	0.3	-0.5
Health satisfaction	1.3	1.7	3.6	-1.2	-1.4	-1.3	-1.6	-1.0	-1.3	-1.2	-1.5	-1.4	1.5	-1.2	-1.2	1.3	-1.6	1.9	1.3	-0.8	-1.6	1.2	-1.3	-1.0	-0.9	-1.1	-1.2	-1.0
Shortness of breath walking on level ground	2.3	2.8	4.8	-1.7	-1.4	-1.8	-2.0	-1.5	-1.8	-1.8	-1.8	-1.8	2.0	-1.5	-1.6	1.8	-2.0	2.2	1.8	-1.8	-1.8	1.8	-0.9	-1.5	-1.4	-1.2	-0.3	-1.3
Qualifications: College or University degree	12.6	39.7	46.6	6.7	4.9	6.6	5.7	6.5	6.6	6.6	6.8	6.6	-6.6	6.0	5.9	-6.6	6.5	-6.3	-6.8	6.4	6.6	-6.4	6.1	6.4	6.4	6.3	4.0	6.3
Eye problems/disorders: None of the above	2.3	2.7	9.4	1.4	1.6	2.0	3.1	0.9	1.9	2.0	1.7	2.0	-1.9	0.6	-0.0	-1.9	2.7	-1.8	-1.7	0.9	1.4	-0.6	0.8	1.3	1.3	1.5	1.6	1.3
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.5	0.6	0.6	0.1	-0.4	0.7	0.1	0.1	0.0	0.2	-0.0	1.0	0.8	-0.1	-1.1	0.4	-0.1	1.1	-0.3	-0.6	1.2	0.4	0.6	0.2	0.3	0.4
Emphysema/chronic bronchitis	9.2	10.4	15.3	-3.5	-2.3	-3.4	-3.1	-3.4	-3.4	-3.5	-3.7	-3.3	3.5	-2.6	-2.8	3.4	-3.9	3.3	3.6	-3.3	-3.5	3.1	-0.9	-3.3	-3.4	-3.6	-1.8	-3.4
Medication for pain relief, constipation, heartburn	16.0	27.4	35.5	5.6	5.1	5.9	5.5	4.9	6.0	5.9	5.5	5.9	-5.9	5.4	4.1	-6.0	5.1	-5.3	-5.8	5.4	5.3	-5.1	3.6	5.0	5.1	4.8	2.1	5.0
Neck or shoulder pain in last month	1.8	2.5	4.0	1.5	1.3	1.8	1.2	1.7	1.7	1.8	1.4	1.8	-1.7	1.8	1.1	-1.7	1.3	-1.3	-1.7	1.6	1.4	-1.4	1.8	2.0	2.0	1.4	1.3	1.9
Medication: Blood pressure	1.3	2.2	5.6	1.4	0.7	1.6	1.1	1.3	1.6	1.5	1.8	1.6	-1.4	1.4	1.2	-1.5	1.1	-0.9	-1.7	1.6	1.5	-1.4	2.2	1.6	1.6	2.4	0.5	1.6
Angina (self-reported)	0.1	0.1	0.8	-0.1	-0.3	-0.1	-0.5	0.1	-0.1	-0.2	-0.2	-0.1	0.1	0.2	0.4	0.1	-0.1	-0.0	0.1	-0.1	0.1	-0.3	-0.0	-0.2	-0.1	0.2	-0.9	-0.2
Migraine (self-reported)	2.0	2.5	6.1	-1.5	-0.9	-1.6	-1.8	-1.3	-1.6	-1.6	-1.4	-1.6	2.0	-1.0	-0.6	1.6	-2.5	2.4	1.6	-1.1	-1.6	1.2	-0.9	-1.8	-1.8	-1.6	-0.4	-1.8
Medication: Ibuprofen	10.7	12.8	21.4	-3.8	-3.0	-3.9	-3.6	-3.0	-3.9	-3.9	-3.9	-4.0	4.3	-3.8	-2.9	3.9	-3.9	4.6	4.0	-3.4	-3.8	3.6	-2.3	-3.2	-3.3	-3.2	-1.4	-3.2
Medication: Allopurinol	2.7	3.6	5.9	2.2	2.1	1.9	1.5	1.7	1.9	2.0	2.3	1.9	-2.1	2.4	2.1	-1.9	1.4	-2.2	-2.1	2.3	2.0	-2.2	1.5	1.8	1.7	1.1	0.3	1.7
Medication: Omeprazole	2.1	2.5	4.5	2.0	1.2	1.6	0.8	1.7	1.6	1.5	1.8	1.4	-1.5	1.7	2.1	-1.6	1.4	-1.2	-1.7	1.9	1.9	-2.1	1.3	1.2	1.2	1.3	1.8	1.3
Medication: Seretide 50 evohaler	0.7	0.8	1.6	0.9	0.3	0.9	0.3	1.3	0.9	0.8	1.1	0.8	-0.9	0.5	0.7	-0.9	1.1	-0.8	-1.0	0.7	0.8	-0.6	1.2	1.0	1.1	1.2	0.6	1.0
Mean time to correctly identify matches	0.5	0.9	7.0	-0.8	-1.5	0.2	0.5	-0.2	0.2	0.2	-1.1	0.2	-0.5	-0.8	-2.3	-0.2	1.1	-0.9	-0.2	-0.4	-0.8	1.0	-0.2	0.0	0.0	-2.6	1.0	0.1
Heart disease (mother)	4.8	5.8	9.4	-2.5	-2.6	-2.4	-3.1	-1.6	-2.5	-2.4	-2.3	-2.4	2.5	-2.0	-2.0	2.5	-2.7	2.5	2.3	-2.0	-2.8	2.4	-1.7	-2.6	-2.7	-2.2	-2.4	-2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.6	6.7	13.0	-2.5	-2.2	-2.7	-2.6	-2.0	-2.7	-2.7	-2.9	-2.8	2.9	-2.4	-1.6	2.7	-2.5	2.9	2.7	-2.1	-2.5	2.1	-3.6	-2.9	-2.9	-2.8	-1.0	-2.8
Whole body fat mass	2.1	8.9	19.6	3.4	2.4	2.8	1.5	3.4	2.8	2.8	3.2	2.8	-2.6	3.4	3.7	-2.7	1.5	-1.8	-3.0	3.9	2.6	-3.4	2.8	3.2	3.3	4.4	1.7	3.3
Leg fat mass (right)	0.5	2.1	6.1	1.7	0.8	1.1	0.1	1.8	1.1	1.1	1.3	1.1	-0.9	1.8	2.2	-1.1	0.0	-0.3	-1.3	2.3	0.9	-1.8	1.4	1.8	1.8	2.5	0.2	1.8
Arm predicted mass (right)	0.2	1.0	3.3	-0.3	-1.5	-0.9	-1.8	0.8	-0.9	-0.9	-1.3	-1.0	1.0	-0.4	0.2	1.0	-1.5	1.2	0.7	0.7	-1.6	0.1	-1.6	-0.7	-0.6	-0.3	-1.1	-0.6
Pulse rate, automated reading	0.9	3.0	5.6	1.8	0.7	2.2	1.6	2.2	2.2	2.2	1.2	2.1	-2.0	1.5	0.4	-2.1	1.8	-1.3	-2.2	2.4	1.0	-1.3	2.4	1.7	1.7	1.0	0.1	1.8
Alcohol intake frequency.	14.7	34.3	40.8	-6.2	-5.2	-6.3	-5.3	-5.3	-6.2	-6.3	-6.1	-6.1	6.2	-5.8	-5.1	6.2	-5.9	5.6	6.3	-5.7	-6.2	6.0	-4.3	-6.3	-6.3	-5.7	-4.9	-6.4
Comparative height size at age 10	5.8	32.0	42.8	6.2	5.1	5.7	4.7	5.8	5.7	5.7	6.0	5.6	-5.9	6.0	6.0	-5.7	4.6	-5.6	-5.9	6.5	5.4	-6.2	5.2	5.4	5.4	6.0	5.3	5.4
Number of full sisters	1.4	1.7	2.4	-1.4	-1.3	-1.4	-1.1	-1.4	-1.5	-1.4	-1.2	-1.4	1.5	-1.5	-1.1	1.5	-1.1	1.5	1.4	-1.5	-1.2	1.4	-1.5	-1.2	-1.2	-1.1	-0.9	-1.0
Suffer from ‘nerves’	9.2	14.4	22.9	-4.4	-3.4	-3.9	-3.4	-3.9	-3.9	-3.9	-4.8	-3.7	4.0	-3.3	-4.0	3.9	-4.5	4.0	4.1	-3.8	-4.4	4.0	-2.4	-3.3	-3.4	-3.5	-2.6	-3.4
Overall health rating	0.7	1.4	2.6	-1.0	-1.4	-1.2	-1.4	-0.6	-1.2	-1.2	-1.5	-1.3	1.3	-1.1	-0.8	1.2	-1.4	1.5	1.2	-0.4	-1.6	0.9	-0.2	-1.1	-1.1	-1.1	-1.6	-1.1
Chest pain or discomfort	0.5	0.7	2.7	0.9	0.5	0.8	0.2	1.3	0.8	0.8	0.5	0.8	-0.4	0.7	0.7	-0.7	0.0	0.4	-0.8	1.1	0.3	-0.6	1.6	1.1	1.1	1.3	0.6	1.1
Had major operations	1.0	1.2	5.2	-0.6	-1.2	-1.1	-2.3	-0.1	-1.1	-1.1	-1.0	-1.1	1.0	-0.2	0.1	1.1	-1.8	1.0	0.8	0.1	-1.4	0.2	-1.4	-1.1	-1.1	-1.6	-0.3	-1.0
Age at last live birth	3.4	4.9	11.0	2.3	1.4	2.2	1.3	2.0	2.2	2.2	2.5	2.2	-2.1	2.4	2.3	-2.1	1.6	-1.9	-2.3	2.3	2.4	-2.4	2.4	2.2	2.3	3.3	1.9	2.4
Family relationship satisfaction	1.3	1.6	4.9	-1.1	-1.4	-1.5	-1.7	-0.7	-1.5	-1.5	-1.5	-1.5	1.8	-1.0	-0.2	1.5	-1.8	2.2	1.4	-0.6	-1.3	0.7	0.2	-0.7	-0.8	-1.0	-0.7	-0.8
Leg pain on walking	8.8	11.1	16.8	-3.0	-3.3	-3.7	-4.1	-2.1	-3.7	-3.7	-3.6	-3.8	3.7	-3.0	-1.9	3.7	-3.7	3.6	3.5	-2.3	-3.8	2.7	-2.9	-3.4	-3.3	-3.5	-2.4	-3.5
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	5.3	-1.2	-1.0	-1.5	-1.3	-0.8	-1.5	-1.5	-0.8	-1.5	1.2	-1.4	-0.8	1.5	-1.3	0.7	1.4	-0.8	-1.8	1.4	-1.3	-1.6	-1.6	-1.3	-2.3	-1.7
Commuting to job workplace: Car/motor vehicle	3.6	4.1	6.0	-2.2	-1.4	-2.2	-1.4	-1.8	-2.2	-2.2	-2.0	-2.1	2.0	-2.2	-2.0	2.2	-1.9	1.4	2.3	-2.3	-2.3	2.5	-2.4	-2.0	-1.9	-1.9	-1.3	-2.0
Illness, injury, bereavement, stress in last 2 years	4.5	5.5	7.7	2.6	2.6	2.4	2.2	1.9	2.4	2.3	2.8	2.3	-2.4	2.4	2.7	-2.4	2.1	-2.3	-2.3	2.2	2.8	-2.6	2.7	2.3	2.3	2.1	1.0	2.2
Medication: Aspirin	0.9	1.2	2.7	-1.1	-1.6	-1.2	-1.3	-0.7	-1.2	-1.3	-0.8	-1.3	1.1	-1.5	-0.8	1.2	-0.3	0.6	1.0	-1.1	-0.9	1.1	-1.6	-1.0	-1.0	-0.8	0.2	-1.0
Supplements: Vitamin C	8.8	10.4	16.3	-3.0	-1.6	-3.6	-3.1	-2.8	-3.6	-3.6	-2.8	-3.6	3.5	-2.6	-1.3	3.6	-3.7	2.9	3.6	-2.8	-3.0	2.5	-3.2	-4.0	-4.0	-3.9	-2.4	-4.0
Knee pain experienced in last month	0.5	0.7	2.5	-0.5	-0.1	-1.0	-1.5	-0.2	-1.0	-1.0	-1.2	-1.1	1.2	-0.1	0.3	1.0	-1.6	1.4	1.0	-0.5	-0.8	0.2	0.3	-0.3	-0.5	-0.5	-0.6	-0.3
Hypertension (Self-reported)	4.5	12.6	17.8	3.9	3.0	3.6	2.9	3.5	3.6	3.5	4.0	3.5	-3.6	3.5	3.6	-3.5	3.2	-3.2	-3.7	3.8	3.6	-3.7	4.1	3.5	3.6	4.2	2.1	3.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.7	6.6	8.7	3.0	2.7	2.7	2.4	2.9	2.8	2.7	2.9	2.6	-2.8	2.5	2.2	-2.8	2.4	-2.6	-2.7	2.9	2.2	-2.4	2.9	2.3	2.3	1.9	2.1	2.2
Illnesses of father: Heart disease	7.2	10.0	13.0	-3.3	-2.7	-3.2	-3.0	-2.3	-3.1	-3.2	-3.3	-3.1	3.3	-3.2	-2.7	3.1	-2.9	3.3	3.2	-3.1	-3.3	3.2	-3.2	-3.6	-3.5	-3.3	-3.1	-3.6
Illnesses of siblings: Diabetes	0.5	0.6	2.3	-0.5	-1.3	-0.6	-1.0	0.2	-0.6	-0.5	-0.7	-0.5	0.5	-0.6	-0.4	0.6	-0.5	0.5	0.5	-0.3	-0.8	0.6	-1.5	-1.2	-1.1	-0.4	-1.0	-1.2
Smoking status: Previous	6.6	9.9	12.5	3.4	3.1	3.3	2.7	3.1	3.3	3.3	3.4	3.3	-3.5	3.5	3.3	-3.3	2.8	-3.5	-3.3	3.2	3.2	-3.4	2.4	3.2	3.1	3.1	1.5	3.1
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	4.3	1.9	1.9	1.6	1.3	1.9	1.6	1.6	1.4	1.5	-1.8	1.9	2.0	-1.6	1.3	-2.1	-1.6	1.9	1.5	-2.0	1.3	0.9	0.8	1.2	0.4	0.8
Whole body fat-free mass	0.1	0.8	2.8	0.1	-1.1	-0.8	-1.7	0.9	-0.8	-0.8	-0.8	-0.8	0.7	0.0	1.0	0.8	-1.4	0.7	0.5	1.0	-1.1	-0.4	-1.5	-0.5	-0.5	0.3	-0.9	-0.5
Leg fat-free mass (right)	0.1	0.6	3.9	1.0	-0.1	-0.0	-1.0	1.5	-0.1	-0.0	0.2	-0.1	-0.0	0.8	2.0	0.1	-0.6	-0.0	-0.3	1.7	-0.1	-1.3	-0.6	0.1	0.1	1.3	-0.3	0.2
Arm fat percentage (left)	1.3	5.2	14.9	2.6	2.1	2.0	1.1	2.3	1.9	2.0	2.6	2.0	-1.8	2.6	3.1	-1.9	1.0	-1.3	-2.1	2.8	2.2	-2.7	2.2	2.5	2.6	3.9	0.8	2.6
Average weekly red wine intake	3.7	5.4	8.9	2.5	1.7	2.7	2.7	2.4	2.7	2.7	1.9	2.6	-2.5	2.1	1.5	-2.7	2.3	-1.9	-2.6	3.0	1.8	-2.3	2.1	2.3	2.3	1.6	2.2	2.3
Handedness (chirality/laterality): Left-handed	23.1	27.8	35.5	5.7	5.3	5.2	3.8	5.0	5.2	5.2	6.0	5.0	-5.2	5.6	5.7	-5.2	4.3	-4.8	-5.3	5.2	5.7	-5.7	5.3	5.5	5.6	5.9	4.6	5.4
Mood swings	30.4	54.9	66.1	-7.9	-5.6	-7.8	-5.7	-7.6	-7.8	-7.8	-8.1	-7.8	7.9	-7.8	-7.1	7.8	-6.5	7.3	8.1	-8.1	-7.4	7.8	-5.7	-7.5	-7.6	-7.7	-6.2	-7.6
Loneliness, isolation	11.8	16.3	20.0	-4.2	-3.8	-4.2	-3.4	-3.3	-4.3	-4.2	-4.5	-4.2	4.2	-4.3	-3.8	4.3	-3.3	3.9	4.3	-4.1	-4.3	4.3	-3.1	-4.1	-4.3	-4.0	-3.9	-4.2
Long-standing illness, disability or infirmity	0.7	1.1	2.0	-1.0	-1.0	-1.2	-1.3	-1.2	-1.1	-1.2	-1.1	-1.2	1.3	-0.8	-0.4	1.1	-1.2	1.4	1.1	-0.8	-0.7	0.6	0.7	-1.0	-1.0	-1.1	-0.9	-1.1
Ever had bowel cancer screening	5.3	6.2	10.4	2.3	1.2	2.7	1.2	2.4	2.6	2.7	2.1	2.7	-2.5	2.6	1.8	-2.6	2.0	-1.9	-2.7	2.4	2.3	-2.4	2.5	3.1	3.2	3.1	2.8	3.2
Diabetes diagnosed by doctor	0.1	0.1	0.8	0.1	-0.4	-0.1	-0.6	0.1	-0.1	-0.2	0.1	-0.2	0.3	-0.0	0.2	0.1	-0.3	0.5	0.0	0.2	-0.0	-0.1	0.9	0.4	0.4	0.6	-0.4	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	-0.0	-0.1	-0.5	-0.6	-0.3	-0.5	-0.5	0.0	-0.7	0.3	-0.1	0.6	0.5	-0.3	-0.0	0.3	0.1	-0.1	-0.3	-0.3	-0.3	-0.2	-0.0	0.6	-0.3
Friendships satisfaction	2.4	3.0	5.0	-2.2	-1.9	-1.8	-1.2	-1.9	-1.8	-1.8	-1.7	-1.7	1.9	-2.1	-1.9	1.8	-1.2	1.7	1.9	-2.2	-1.5	2.1	-0.9	-1.5	-1.6	-1.1	-1.2	-1.6
Qualifications: nursing, teaching	4.5	7.0	12.1	2.8	1.4	2.6	1.1	3.5	2.6	2.6	2.7	2.5	-2.5	2.6	2.8	-2.6	2.4	-2.2	-2.9	2.8	2.7	-2.9	1.9	2.9	2.9	2.8	3.5	2.8
Commuting to job workplace: Walk	0.2	0.2	0.6	0.5	0.5	0.3	-0.2	0.0	0.3	0.3	0.5	0.3	-0.3	0.7	0.8	-0.3	-0.0	-0.2	-0.4	0.5	0.6	-0.8	0.5	0.2	0.1	-0.0	0.2	0.1
Eye problems/disorders: Cataract	2.0	2.3	3.9	-1.7	-1.8	-1.6	-2.0	-1.2	-1.6	-1.6	-1.5	-1.6	1.6	-1.2	-1.3	1.6	-2.0	1.7	1.5	-1.1	-1.8	1.5	-0.6	-1.3	-1.3	-1.7	-0.8	-1.4
Mouth/teeth dental problems: Mouth ulcers	21.5	34.2	42.0	-6.2	-5.3	-6.4	-5.8	-5.6	-6.5	-6.4	-6.0	-6.3	6.3	-5.4	-4.5	6.5	-6.3	5.9	6.2	-5.1	-6.3	5.4	-4.6	-6.2	-6.3	-5.3	-4.2	-6.2
Medication for cholesterol	7.7	11.6	18.9	-3.7	-4.3	-3.5	-2.8	-2.6	-3.5	-3.5	-4.0	-3.4	3.6	-4.0	-3.4	3.6	-2.4	3.3	3.5	-3.2	-3.6	3.5	-2.3	-3.3	-3.4	-3.6	-3.3	-3.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	4.8	0.1	-0.3	0.4	0.2	0.6	0.4	0.4	-0.1	0.5	-0.3	0.3	-0.3	-0.4	0.1	0.1	-0.4	0.3	-0.2	0.0	2.2	0.9	0.8	0.3	0.4	0.8
Back pain experienced in last month	0.2	0.3	1.5	0.0	-0.6	0.4	0.1	0.8	0.4	0.4	-0.6	0.5	-0.4	0.2	-0.3	-0.4	0.5	-0.3	-0.4	0.4	-0.1	-0.2	1.1	0.9	0.8	0.2	1.2	0.9
Mineral and other dietary supplements	0.8	1.1	2.9	1.0	0.2	1.3	0.3	1.7	1.3	1.4	0.7	1.4	-1.2	1.1	0.3	-1.3	0.9	-0.7	-1.4	1.3	0.6	-0.8	-0.0	1.1	1.2	1.3	0.1	1.2
Breast cancer (self-reported)	7.0	8.4	13.0	3.4	2.5	3.3	2.1	3.6	3.4	3.3	2.5	3.3	-3.0	3.4	2.8	-3.4	2.2	-2.2	-3.3	3.6	2.7	-3.3	1.3	2.8	2.7	1.7	2.5	2.7
Asthma (self-reported)	0.7	1.3	8.2	0.9	0.8	1.0	1.4	1.2	0.9	1.0	1.2	0.9	-0.9	-0.3	-0.0	-0.9	2.2	-0.9	-0.8	-0.3	1.2	0.1	2.9	0.7	0.6	0.3	2.0	0.7
Osteoporosis (self-reported)	5.4	6.7	10.3	-2.8	-2.9	-2.9	-2.9	-3.2	-2.9	-2.9	-2.9	-2.9	2.9	-2.5	-2.2	2.9	-2.4	2.5	2.7	-2.7	-2.3	2.2	-0.9	-2.1	-2.2	-2.8	-1.9	-2.2
Osteoarthritis (self-reported)	0.3	0.4	2.2	-0.3	-0.9	-0.2	-0.7	0.7	-0.2	-0.2	-0.8	-0.2	0.7	-0.6	-0.6	0.2	-0.6	1.5	0.3	0.1	-0.9	0.6	0.1	0.6	0.6	0.3	1.2	0.7
Medication: Aspirin	0.6	0.8	1.9	-0.9	-1.1	-1.0	-1.2	-0.6	-1.0	-1.1	-0.5	-1.1	0.9	-1.1	-0.5	1.0	-0.4	0.5	0.9	-1.0	-0.7	0.9	-1.4	-0.9	-0.9	-0.9	0.0	-0.9
Medication: Gliclazide	1.7	2.0	3.9	-1.7	-1.2	-1.4	-1.1	-1.5	-1.4	-1.5	-1.5	-1.4	1.4	-1.6	-1.8	1.4	-1.3	1.3	1.5	-1.6	-1.8	1.8	-0.2	-0.9	-1.0	-0.2	-2.0	-0.9
Illnesses of father: None of the above (group 1)	4.3	5.4	7.8	2.4	2.7	2.1	2.0	1.6	2.0	2.1	2.4	2.1	-2.2	2.7	2.6	-2.0	1.3	-2.1	-2.1	2.4	2.2	-2.5	2.8	2.7	2.7	2.6	2.2	2.7
Smoking status: Current	1.5	2.4	4.9	1.8	2.0	1.6	1.3	1.3	1.6	1.6	1.7	1.6	-1.4	1.8	1.6	-1.5	0.8	-1.0	-1.5	1.6	1.7	-1.6	2.2	1.6	1.5	1.5	0.9	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	29.2	61.6	74.2	8.1	6.3	8.2	7.6	7.8	8.2	8.2	8.4	8.1	-8.5	6.9	6.2	-8.2	8.6	-8.5	-8.3	7.3	7.9	-7.1	7.5	8.3	8.3	8.4	6.5	8.2
Whole body water mass	0.1	0.9	3.0	0.0	-1.1	-0.9	-1.7	0.8	-0.9	-0.9	-0.9	-0.9	0.8	-0.1	0.9	0.9	-1.5	0.8	0.6	0.9	-1.2	-0.3	-1.6	-0.6	-0.6	0.2	-1.1	-0.6
Leg predicted mass (right)	0.1	0.6	3.5	0.9	-0.2	-0.1	-1.1	1.4	-0.2	-0.1	0.1	-0.2	0.1	0.8	1.9	0.2	-0.7	0.0	-0.2	1.6	-0.2	-1.2	-0.7	0.1	0.1	1.3	-0.3	0.1
Arm fat mass (left)	0.6	2.6	8.8	2.0	1.3	1.2	0.1	2.0	1.1	1.2	1.7	1.1	-1.0	2.1	2.7	-1.1	0.0	-0.5	-1.4	2.5	1.2	-2.1	1.2	1.7	1.8	3.0	0.3	1.8
Number of self-reported non-cancer illnesses	0.4	0.7	2.4	-0.8	-1.3	-0.8	-1.0	-0.0	-0.8	-0.8	-0.9	-0.7	1.1	-1.2	-0.7	0.8	-0.4	1.6	0.7	-0.7	-0.7	1.0	1.3	-0.5	-0.5	-0.3	0.2	-0.6
Average weekly champagne plus white wine intake	13.9	19.1	23.5	4.6	4.2	4.8	4.1	4.7	4.8	4.8	4.3	4.8	-4.4	4.4	3.8	-4.8	3.7	-3.2	-4.6	4.6	4.2	-4.2	4.3	4.4	4.4	4.3	4.1	4.4
Miserableness	18.3	31.7	43.4	-6.2	-3.8	-5.9	-3.1	-6.4	-5.9	-5.8	-5.9	-5.8	5.6	-6.2	-6.3	5.9	-4.6	4.7	6.2	-6.5	-6.0	6.6	-3.8	-5.5	-5.8	-5.7	-5.1	-5.7
Guilty feelings	14.2	21.4	28.6	-4.9	-2.9	-5.1	-3.8	-4.9	-5.1	-5.0	-4.8	-5.1	5.0	-4.4	-4.1	5.0	-5.2	4.6	5.2	-4.3	-5.3	4.9	-2.9	-4.3	-4.4	-4.6	-4.3	-4.4
Wears glasses or contact lenses	0.5	0.5	1.4	-0.9	-0.9	-0.6	-0.9	-0.6	-0.7	-0.7	-1.2	-0.5	0.6	-0.5	-1.1	0.7	-0.9	0.6	0.7	-0.8	-0.9	0.9	-1.1	-0.4	-0.3	-0.3	-0.3	-0.4
Ever taken oral contraceptive pill	4.8	5.4	10.3	-2.6	-3.2	-2.4	-2.6	-1.6	-2.4	-2.4	-2.8	-2.2	2.6	-2.2	-1.7	2.4	-2.4	2.6	2.3	-1.9	-2.4	1.9	-1.2	-2.1	-2.1	-1.9	-2.7	-2.1
Hearing aid user	3.2	3.6	5.0	-2.2	-1.7	-2.2	-1.6	-1.7	-2.2	-2.2	-2.1	-2.0	2.0	-1.8	-1.6	2.2	-2.1	1.6	2.2	-2.1	-2.2	2.0	-1.3	-1.9	-1.8	-1.4	-0.6	-1.9
Mother’s age at death	0.3	0.4	1.1	0.7	0.5	0.8	0.2	0.2	0.7	0.8	0.7	0.7	-0.4	0.9	0.7	-0.7	0.1	0.3	-0.8	0.8	1.1	-0.9	-0.5	0.4	0.5	-0.3	0.0	0.5
Financial situation satisfaction	0.3	0.3	0.9	-0.2	-0.8	-0.6	-0.2	-0.2	-0.6	-0.6	-0.2	-0.8	0.4	-0.9	-0.3	0.6	0.2	0.1	0.4	-0.2	-0.5	0.5	0.5	-0.8	-0.9	-0.4	-0.6	-0.9
Tinnitus: Yes, now most or all of the time	1.7	2.0	4.7	-1.5	-1.4	-1.3	-1.6	-0.6	-1.3	-1.3	-2.0	-1.2	1.5	-1.3	-1.7	1.4	-1.8	1.9	1.4	-0.9	-2.2	1.6	-1.1	-0.9	-0.7	-0.9	-1.6	-0.8
Commuting to job workplace: Public transport	3.8	4.5	6.2	2.1	2.1	2.4	2.0	1.6	2.4	2.4	2.0	2.4	-2.4	2.3	1.4	-2.4	2.2	-2.2	-2.3	1.6	2.4	-2.1	1.2	2.5	2.4	1.8	1.4	2.5
Eye problems/disorders: Glaucoma	7.0	8.2	11.1	-3.1	-1.8	-3.0	-2.4	-2.7	-3.0	-3.0	-3.3	-3.0	3.0	-2.7	-2.6	3.0	-2.7	2.8	3.1	-3.2	-2.8	2.8	-3.2	-2.9	-2.9	-2.6	-2.9	-2.9
Medication: Blood pressure	11.2	21.2	28.7	5.1	4.8	4.8	4.0	4.1	4.9	4.8	5.4	4.8	-5.1	5.1	4.4	-4.9	3.9	-4.9	-4.9	4.7	4.7	-4.7	3.9	4.2	4.4	4.7	3.3	4.2
Pain type(s) experienced in last month: Hip pain	3.2	4.1	7.3	-1.7	-1.5	-2.2	-2.7	-2.0	-2.2	-2.2	-2.3	-2.4	2.3	-1.3	-0.8	2.1	-2.6	2.4	2.1	-1.6	-1.8	1.1	-2.2	-2.0	-2.0	-2.2	-1.4	-2.0
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.6	-0.2	-0.1	-0.3	0.6	-0.5	-0.3	-0.3	0.1	-0.3	0.1	-0.3	0.2	0.3	0.3	-0.4	0.3	-0.2	0.1	0.0	0.3	-0.7	-0.8	-0.6	-0.0	-0.7
High cholesterol (Self-reported)	1.1	1.9	4.4	1.3	1.0	1.3	1.2	0.7	1.3	1.3	1.8	1.3	-1.2	1.1	1.0	-1.4	1.4	-1.0	-1.4	0.8	1.8	-1.1	1.8	1.7	1.7	2.1	1.0	1.7
Medication: Bendroflumethiazide	3.9	5.9	10.4	2.9	2.0	2.5	1.6	2.5	2.5	2.5	3.2	2.4	-2.5	2.5	2.9	-2.5	2.1	-2.1	-2.7	2.9	2.6	-2.8	1.8	2.2	2.2	2.4	1.5	2.2
Medication: Paracetamol	28.7	44.4	57.0	-7.2	-6.7	-7.5	-7.0	-6.4	-7.5	-7.5	-7.1	-7.4	7.4	-6.7	-5.1	7.5	-6.6	6.5	7.3	-6.7	-6.7	6.3	-4.6	-6.4	-6.5	-6.1	-3.5	-6.3
Medication: Lisinopril	3.1	4.0	7.2	2.2	1.3	1.8	1.4	2.3	1.7	1.7	2.6	1.8	-2.1	2.0	2.7	-1.7	1.7	-2.4	-2.0	2.6	1.8	-2.2	2.0	1.7	1.7	2.1	2.1	1.6
Medication: Atorvastatin	0.2	0.2	1.7	-0.3	-1.3	-0.2	-0.2	-0.0	-0.2	-0.2	-0.1	-0.3	-0.1	-0.8	-0.5	0.2	1.1	-0.6	0.0	-0.6	0.1	0.3	0.2	0.1	0.1	0.5	0.4	0.1
Illnesses of father: High blood pressure	1.4	1.8	2.5	1.3	0.6	1.4	1.2	1.1	1.5	1.4	1.5	1.4	-1.4	1.0	0.9	-1.5	1.5	-1.2	-1.5	1.4	1.4	-1.2	1.5	1.6	1.4	1.4	0.2	1.5
Alcohol drinker status: Never	1.7	2.0	4.4	-1.4	-1.1	-1.3	-1.3	-0.9	-1.3	-1.3	-1.2	-1.1	1.3	-0.9	-0.9	1.3	-1.5	1.2	1.3	-1.2	-1.2	1.2	-1.4	-2.1	-2.1	-1.9	-1.8	-2.1
Ever smoked	4.3	7.5	10.8	2.8	3.0	2.6	2.6	2.2	2.6	2.6	2.9	2.7	-2.9	3.0	3.1	-2.6	2.5	-3.3	-2.6	2.4	3.1	-3.0	2.6	2.9	2.8	2.7	1.4	2.8
Basal metabolic rate	0.1	0.6	2.2	0.6	-0.6	-0.4	-1.3	1.3	-0.4	-0.4	-0.3	-0.4	0.4	0.5	1.5	0.4	-1.1	0.5	0.1	1.5	-0.7	-0.8	-0.9	-0.1	-0.1	0.9	-0.7	-0.1
Leg fat percentage (left)	0.6	2.2	5.6	1.6	0.8	1.4	0.5	1.7	1.4	1.4	1.3	1.4	-1.1	1.6	1.6	-1.3	0.4	-0.3	-1.5	2.1	1.0	-1.6	1.6	2.0	2.1	2.4	0.5	2.1
Arm fat-free mass (left)	0.2	0.9	3.2	-0.1	-1.2	-0.9	-1.8	0.8	-0.9	-0.9	-1.0	-0.9	0.9	-0.1	0.6	0.9	-1.6	1.1	0.6	1.0	-1.4	-0.1	-1.5	-0.4	-0.4	0.1	-1.1	-0.4
Number of operations (self-reported)	2.9	4.3	11.3	-1.8	-2.2	-2.3	-3.4	-1.0	-2.3	-2.3	-2.3	-2.4	2.2	-1.5	-1.1	2.4	-2.7	2.1	2.0	-1.1	-2.7	1.5	-1.9	-2.0	-2.0	-2.1	-0.5	-2.0
Average weekly beer plus cider intake	3.0	4.3	6.6	2.2	2.0	2.1	1.2	2.3	2.1	2.2	2.1	2.1	-2.4	2.6	1.6	-2.1	1.1	-2.3	-2.2	2.4	1.2	-1.8	2.6	2.3	2.3	1.8	1.6	2.3
Irritability	17.9	30.4	36.1	-5.8	-4.7	-5.9	-4.4	-5.4	-5.9	-5.9	-6.0	-5.8	5.9	-5.6	-4.8	5.9	-5.0	5.3	6.0	-5.6	-5.6	5.4	-4.8	-5.8	-5.8	-5.7	-3.8	-5.9
Risk taking	1.7	2.5	4.8	-1.8	-1.4	-1.5	-1.3	-1.7	-1.5	-1.5	-2.0	-1.5	1.4	-1.5	-2.2	1.5	-1.5	1.3	1.6	-1.6	-2.0	1.9	-1.5	-1.2	-1.3	-2.1	-1.1	-1.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	0.2	0.2	0.4	-0.5	0.7	0.4	0.4	0.3	0.5	-0.0	0.7	0.9	-0.4	-0.3	0.5	-0.3	0.0	0.7	-0.6	-0.3	0.4	0.4	0.9	1.1	0.5
Fractured/broken bones in last 5 years	9.0	11.6	18.7	-3.4	-3.2	-3.6	-3.5	-2.4	-3.6	-3.6	-4.0	-3.6	3.3	-3.3	-2.7	3.6	-2.9	2.7	3.5	-3.3	-3.6	3.1	-3.3	-3.9	-3.9	-4.3	-1.6	-4.0
Age started oral contraceptive pill	2.5	3.1	5.5	2.0	1.6	1.8	0.9	1.7	1.8	1.8	2.0	1.7	-1.7	2.2	2.3	-1.8	1.4	-1.6	-1.9	1.9	2.2	-2.3	0.5	1.6	1.7	1.1	1.6	1.7
Diastolic blood pressure, automated reading	2.8	8.6	14.3	3.1	2.1	3.3	2.5	3.8	3.3	3.3	2.9	3.2	-3.1	2.6	2.0	-3.3	2.9	-2.2	-3.3	3.4	2.3	-2.5	3.6	2.7	2.7	3.3	2.1	2.7
Ever depressed for a whole week	10.8	13.4	19.4	-4.2	-3.2	-3.7	-2.5	-3.4	-3.7	-3.8	-4.0	-3.5	3.8	-4.0	-3.9	3.7	-3.0	3.5	4.0	-4.4	-3.5	4.3	-2.7	-3.8	-3.6	-3.6	-3.4	-3.9
Unable to work because of sickness or disability	0.3	0.3	2.4	-0.3	-0.1	-0.6	-0.7	-0.4	-0.5	-0.6	-0.5	-0.6	0.6	-0.1	0.1	0.5	-0.8	0.6	0.5	-0.1	-0.4	0.1	0.8	-0.6	-0.6	-0.4	-1.5	-0.6
Commuting to job workplace: Cycle	0.2	0.2	1.4	0.1	0.5	0.1	1.2	-0.6	0.1	0.1	0.5	0.1	-0.4	-0.2	-0.0	-0.0	0.8	-1.0	-0.1	-0.2	0.4	-0.0	0.3	0.3	0.3	0.6	0.4	0.2
Myopia	9.1	13.2	16.2	3.7	3.4	3.7	3.4	2.9	3.7	3.7	3.8	3.8	-4.0	3.7	3.0	-3.7	3.3	-4.0	-3.7	3.5	3.6	-3.5	3.3	3.8	3.9	3.8	3.5	4.0
Vascular/heart problems diagnosed by doctor	3.6	9.8	14.2	-3.4	-2.7	-3.2	-2.8	-2.8	-3.2	-3.2	-3.6	-3.2	3.2	-3.1	-3.0	3.1	-2.9	2.9	3.3	-3.3	-3.3	3.2	-3.7	-3.0	-3.2	-3.8	-1.5	-3.0
Cholesterol lowering medication	1.3	1.9	3.1	1.4	1.2	1.3	0.8	1.1	1.3	1.3	1.8	1.3	-1.2	1.5	1.5	-1.3	0.9	-1.0	-1.4	1.3	1.6	-1.4	1.6	1.6	1.5	1.4	1.4	1.6
Medication: Omeprazole (e.g. Zanprol)	3.2	3.9	5.8	2.4	1.6	2.0	1.3	1.9	2.0	2.0	2.4	1.8	-2.0	2.0	2.3	-2.0	2.2	-1.9	-2.2	2.1	2.4	-2.4	1.8	1.4	1.4	1.3	2.1	1.5
Pain experienced in last month	8.4	14.0	21.5	4.0	3.4	4.2	4.1	3.1	4.2	4.2	4.6	4.1	-4.3	3.5	3.0	-4.3	4.2	-4.2	-4.2	3.5	4.3	-3.6	2.1	3.1	3.2	3.7	1.6	3.1
Supplements: Calcium	0.8	0.8	2.5	-0.5	-0.2	-1.1	-1.6	-0.7	-1.1	-1.2	-0.7	-1.3	1.2	-0.5	0.1	1.1	-1.5	1.1	1.1	-0.5	-0.9	0.5	-0.2	-0.7	-0.7	-1.0	-0.3	-0.6
Basal cell carcinoma (self-reported)	0.1	0.2	1.4	0.1	0.3	-0.2	-0.3	-0.2	-0.1	-0.2	-0.2	-0.2	0.4	0.1	0.3	0.1	-0.7	0.7	0.3	0.1	-0.2	-0.2	1.2	-0.1	-0.2	-0.6	0.6	-0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.9	-0.7	-0.9	-0.4	-0.3	0.0	-0.4	-0.4	-0.7	-0.3	0.2	-0.6	-0.6	0.3	-0.0	-0.1	0.4	-0.4	-0.7	0.6	-0.7	-0.6	-0.5	-0.9	-0.5	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.9	-0.9	-1.2	-0.7	-1.1	-0.1	-0.7	-0.7	-1.1	-0.6	0.9	-0.9	-1.0	0.7	-0.9	1.4	0.8	-0.6	-1.2	1.0	0.2	-0.1	-0.3	0.1	-0.1	-0.1
Heart disease (siblings)	9.0	11.0	14.5	-3.7	-2.6	-3.5	-3.2	-3.8	-3.5	-3.5	-3.5	-3.5	3.6	-3.2	-3.1	3.5	-3.3	3.3	3.6	-3.8	-3.1	3.3	-2.6	-3.0	-3.1	-3.4	-2.7	-3.1
Alcohol drinker status: Previous	0.3	0.3	3.1	0.5	0.0	0.5	0.2	0.5	0.5	0.5	0.7	0.6	-0.3	0.6	0.5	-0.5	-0.2	0.3	-0.6	0.9	0.2	-0.3	1.8	0.1	0.1	-0.0	-0.7	0.0
Pack years of smoking	1.4	2.1	4.5	-1.5	-1.5	-1.4	-1.5	-1.5	-1.4	-1.4	-1.7	-1.5	1.6	-1.6	-2.1	1.5	-1.5	1.8	1.4	-1.5	-1.8	1.9	-0.5	-0.8	-0.8	-0.3	-1.5	-0.8
Impedance of whole body	9.3	47.4	59.6	6.8	7.6	7.5	7.4	5.5	7.5	7.5	7.7	7.4	-7.2	6.4	4.9	-7.5	6.8	-6.3	-7.1	5.7	7.4	-5.8	7.6	6.7	6.7	7.5	5.9	6.8
Leg fat mass (left)	0.6	2.2	6.2	1.7	0.9	1.2	0.1	1.8	1.1	1.2	1.3	1.2	-1.0	1.8	2.1	-1.1	0.1	-0.3	-1.4	2.2	1.0	-1.8	1.2	1.8	1.9	2.5	0.4	1.9
Arm predicted mass (left)	0.1	0.6	2.2	0.2	-1.1	-0.5	-1.5	1.1	-0.5	-0.5	-0.7	-0.5	0.5	0.1	0.8	0.5	-1.1	0.8	0.2	1.2	-1.1	-0.4	-1.3	-0.1	-0.1	0.4	-1.1	-0.0