Best TWAS P=2.18e-10 · Best GWAS P=1.02e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | ZMYM5 | 0.09 | 0.04 | enet | 12 | 0.06 | 2.6e-05 | 5.5 | -5.2 | 2.1e-07 | -0.71 | 0.09 | 0.81 | FALSE |
2 | GTEx | Nerve Tibial | RP11-523H24.3 | 0.05 | 0.01 | lasso | 3 | 0.01 | 8.2e-02 | 4.8 | -5.4 | 5.5e-08 | -0.87 | 0.04 | 0.92 | FALSE |
3 | GTEx | Thyroid | PSPC1 | 0.11 | 0.04 | lasso | 4 | 0.02 | 7.4e-03 | 6.1 | -6.3 | 2.2e-10 | -0.98 | 0.01 | 0.99 | TRUE |