Best TWAS P=1.82e-08 · Best GWAS P=8.41e-08 conditioned to 0.0318
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | TNFSF12 | 0.06 | 0.07 | bslmm | 462 | 0.07 | 9.4e-23 | 4.6 | 5.1 | 2.8e-07 | 0.00 | 0.10 | 0.87 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C17orf81 | 0.04 | 0.05 | enet | 8 | 0.04 | 1.2e-05 | -3.8 | -5.2 | 1.9e-07 | -0.67 | 0.02 | 0.48 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CHRNB1 | 0.03 | 0.02 | blup | 57 | 0.02 | 7.8e-04 | -4.4 | -5.6 | 1.8e-08 | -0.05 | 0.01 | 0.92 | TRUE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CHRNB1 | 0.06 | 0.00 | blup | 57 | 0.03 | 4.5e-03 | -1.6 | -5.3 | 1.2e-07 | -0.03 | 0.00 | 0.40 | FALSE |