TWAS hub - TNFSF12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1127	0.0445	2.4e-03	0.062	NA	0.030	NA	0.048	1.2e-05	NA	2.0e-03	NA	1.2e-04
2	GTEx	Cells Transformed fibroblasts	0.2500	0.0460	1.0e-10	0.222	NA	0.196	NA	0.199	1.4e-16	NA	1.2e-14	NA	7.4e-15
3	GTEx	Whole Blood	0.0870	0.0330	2.6e-03	0.026	NA	0.038	NA	0.033	1.7e-03	NA	1.9e-04	NA	5.1e-04
4	METSIM	Adipose	0.1189	0.0328	3.5e-06	0.032	0.045	0.045	0.049	0.044	1.0e-05	2.7e-07	2.0e-07	7.3e-08	3.0e-07
5	NTR	Blood	0.0647	0.0134	0.0e+00	0.070	0.064	0.070	0.074	0.070	1.3e-21	5.9e-20	1.7e-21	9.4e-23	1.2e-21
6	ROSMAP	Brain Pre-frontal Cortex	0.1018	0.0284	5.5e-06	0.041	0.049	0.040	0.053	0.056	4.4e-06	5.8e-07	6.0e-06	2.4e-07	9.2e-08
7	YFS	Blood	0.0985	0.0177	0.0e+00	0.117	0.099	0.124	0.119	0.126	2.4e-36	1.5e-30	3.0e-38	6.4e-37	6.1e-39
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0364	0.0232	9.9e-03	0.006	0.003	0.008	NA	0.006	5.9e-02	1.3e-01	4.3e-02	NA	6.3e-02
9	TCGA	Brain Lower Grade Glioma	0.0468	0.0228	6.3e-04	0.001	0.013	0.010	NA	0.000	2.5e-01	1.2e-02	2.4e-02	NA	3.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	8	9
Medication: Amlodipine	9.2	13.0	23.6	-4.5	3.7	4.0	-3.1	4.6	2.0	-4.9	2.8
High blood pressure	7.8	21.7	46.0	-3.0	5.7	4.7	-1.2	6.1	5.3	-6.8	4.5
Impedance of arm (right)	7.7	36.1	70.9	-1.8	8.0	8.3	-1.4	7.0	8.4	-6.6	5.0
Hypertension (Self-reported)	7.4	20.7	41.6	-2.9	5.6	4.7	-1.7	5.9	5.0	-6.4	4.4
Systolic Blood Pressure	7.3	36.7	70.1	-5.1	7.7	5.2	-3.6	8.4	6.8	-7.2	6.0
Impedance of arm (left)	7.2	33.3	69.7	-2.3	7.7	8.3	-1.9	6.6	7.8	-5.9	4.6
Systolic blood pressure, automated reading	6.8	19.9	36.4	-3.0	5.6	4.4	-2.3	6.0	4.5	-6.0	4.7
Medication: Blood pressure	6.8	13.0	24.7	-2.9	4.7	2.9	-1.8	5.0	4.2	-4.3	3.7
Medication: Bendroflumethiazide	6.4	9.8	21.3	-2.8	3.8	2.0	-0.4	4.6	3.1	-4.5	3.2
Vascular/heart problems diagnosed by doctor	5.9	16.0	33.2	2.2	-5.0	-3.7	1.1	-5.2	-4.9	5.8	-3.9
Had other major operations	5.5	6.8	11.9	-2.4	3.2	3.1	-1.3	3.5	2.9	-2.2	2.8
Waist Hip Ratio (WHR)	4.4	19.9	46.5	3.2	-6.1	-5.4	5.1	-6.8	-5.1	1.9	-1.0
Trunk predicted mass	4.2	23.9	54.6	7.4	-5.3	-7.0	2.5	-5.0	-3.7	3.2	-5.2
Respiratory disease	4.1	9.1	19.5	4.4	-3.2	-3.3	4.3	-3.6	-2.5	1.6	-0.8
Trunk fat-free mass	4.1	23.4	54.2	7.4	-5.2	-7.0	2.5	-5.0	-3.6	3.1	-5.2
Hand grip strength (right)	4.0	10.8	18.9	2.6	-4.3	-4.0	0.6	-3.9	-3.9	3.4	-3.6
Impedance of whole body	4.0	20.5	44.9	-2.3	5.8	6.7	-0.4	4.9	6.1	-4.9	4.0
Arm predicted mass (right)	3.8	19.2	42.5	5.5	-5.2	-6.5	1.9	-4.5	-4.2	3.4	-4.6
Lupus	3.7	5.6	13.2	1.0	3.3	2.5	0.3	2.8	3.6	-2.9	1.4
Cardiovascular Disease	3.7	12.2	26.2	-3.2	4.0	2.9	-2.3	4.5	3.6	-5.1	3.1
Trunk fat percentage	3.7	14.7	30.0	-1.6	5.1	4.0	-2.4	5.5	4.8	-4.2	3.3
Birth weight	3.7	8.1	20.6	0.7	-2.8	-4.5	-2.6	-2.7	-2.3	3.2	-3.8
Medication: Blood pressure	3.6	6.3	16.3	-2.5	2.7	2.8	-1.1	2.9	2.3	-4.0	2.0
Arm fat percentage (left)	3.6	14.3	29.9	-2.4	5.0	3.9	-3.7	5.5	4.2	-3.5	3.0
Arm fat-free mass (left)	3.6	18.1	40.7	6.2	-4.8	-6.4	2.0	-4.2	-3.5	2.8	-4.2
Arm predicted mass (left)	3.6	18.1	39.6	6.3	-4.8	-6.3	1.9	-4.3	-3.6	2.8	-4.2
Arm fat-free mass (right)	3.5	18.2	41.9	5.3	-5.0	-6.5	2.0	-4.4	-4.0	3.1	-4.4
Deep venous thrombosis (DVT) (self-reported)	3.5	4.5	6.3	-1.9	2.3	2.4	-2.0	2.5	1.9	-2.5	2.5
Medication: Allopurinol	3.4	4.5	8.0	-2.8	2.2	2.0	-1.6	2.3	2.1	-2.7	2.1
Arm fat percentage (right)	3.3	13.1	27.8	-1.8	4.8	3.6	-3.1	5.3	4.3	-3.6	3.0
Medication: Cholesterol lowering	3.2	5.0	10.4	-0.5	-3.2	-2.9	-0.4	-2.8	-2.9	2.1	-2.3
Blood clot in the leg (DVT)	3.2	4.1	5.7	-1.9	2.2	2.4	-2.4	2.2	1.8	-2.1	2.2
Bipolar Disorder (2018)	3.1	4.9	16.1	-1.5	-1.9	-1.9	-1.7	-2.0	-1.9	4.0	-2.9
Body fat percentage	3.1	12.4	26.4	-2.0	4.7	3.6	-2.5	5.1	4.2	-3.7	3.0
Whole body fat-free mass	3.1	17.5	38.9	6.2	-4.5	-6.2	1.6	-4.0	-3.2	2.8	-4.7
Alcohol intake versus 10 years previously	2.9	4.4	9.7	2.5	-2.7	-2.1	1.9	-3.1	-2.6	1.4	-0.2
Whole body water mass	2.9	16.7	38.8	6.2	-4.4	-6.1	1.5	-3.9	-3.1	2.7	-4.6
Medication: Co-codamol	2.8	3.2	7.8	-0.4	2.1	1.7	-0.2	2.2	2.8	-2.4	1.8
Family relationship satisfaction	2.8	3.5	7.1	2.0	2.3	2.1	-0.7	1.8	2.7	-2.4	1.2
Medication: Lisinopril	2.8	3.6	6.2	-1.3	2.5	1.5	-1.2	2.5	2.4	-2.5	1.6
Stomach or abdominal pain in last month	2.7	3.4	17.3	-1.0	1.4	2.4	-4.2	1.8	0.9	0.3	-0.8
Diastolic blood pressure, automated reading	2.7	8.4	20.2	1.8	3.7	1.9	-0.6	4.1	3.6	-4.5	2.2
Qualifications: A levels/AS levels or equivalent	2.6	5.8	15.8	1.4	-2.4	-2.8	1.0	-2.7	-1.8	3.0	-4.0
Qualifications: O levels/GCSEs or equivalent	2.6	4.1	13.8	1.4	-1.7	-2.1	-0.6	-1.7	-1.6	2.9	-3.7
Pulse rate, automated reading	2.6	8.4	15.8	1.7	-3.8	-4.0	3.4	-3.8	-2.6	1.8	-2.7
Relative age of first facial hair	2.5	5.2	11.2	-1.2	3.3	2.9	-3.1	2.6	2.8	-0.8	0.9
Medication for cholesterol	2.5	3.8	8.0	1.6	-2.7	-0.6	1.1	-2.8	-2.3	2.4	-2.0
Height	2.4	47.2	246.5	15.7	-3.5	-5.6	6.8	-5.3	-0.3	3.3	-7.0
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	6.6	2.6	-1.6	-2.1	2.2	-1.6	-1.0	0.6	0.8
High blood pressure (siblings)	2.4	3.5	6.0	-1.8	2.2	1.7	-0.3	2.3	2.0	-2.4	2.2
Ever taken oral contraceptive pill	2.4	2.7	6.4	0.1	-2.3	-1.4	-0.6	-2.5	-2.2	1.9	-1.4
Alcohol usually taken with meals	2.3	3.8	8.0	1.6	-1.9	-2.3	0.9	-2.7	-1.3	2.0	-2.8
Illnesses of father: High blood pressure	2.3	2.9	7.1	-1.0	2.3	1.6	-1.2	2.7	2.2	-1.7	1.1
Number of operations (self-reported)	2.3	3.4	7.2	-2.6	1.9	1.2	-1.1	2.7	2.3	-1.6	1.3
HbA1C	2.1	2.3	5.9	-0.5	-2.4	-2.0	0.7	-1.9	-2.4	0.6	0.1
Hand grip strength (left)	2.1	5.5	9.0	3.0	-2.9	-2.6	1.8	-2.5	-2.2	2.2	-2.4
Number of live births	2.1	3.0	8.5	-2.3	1.8	2.9	-1.5	1.7	0.6	-1.2	1.7
Standing height	2.1	20.5	110.2	10.5	-2.6	-4.0	4.3	-3.5	0.4	0.1	-4.5
Length of working week for main job	2.1	2.3	6.9	2.6	-1.4	-1.5	2.1	-1.9	-0.3	0.7	-0.9
Gout (self-reported)	2.1	2.9	6.9	-2.6	1.8	1.1	-1.2	2.1	1.7	-2.0	1.4
Illnesses of siblings: Diabetes	2.1	2.6	5.2	-1.7	-2.3	-1.9	0.8	-2.0	-2.0	1.5	0.8
Basal metabolic rate	2.1	11.7	32.7	5.7	-3.5	-5.1	1.1	-2.9	-2.2	2.0	-3.9
Birth weight of first child	2.0	3.7	14.4	3.8	-1.5	-2.8	0.3	-1.7	-0.8	1.2	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.3	17.1	4.1	-1.5	-2.4	1.1	-2.2	0.1	1.2	-2.4
Irritability	2.0	3.4	8.8	-0.4	-2.4	-1.9	-0.4	-1.4	-2.2	3.0	-2.4
Type 2 Diabetes (T2D) (2012)	1.9	2.2	4.5	-0.1	-1.8	-2.1	0.5	-1.9	-1.6	1.5	-1.6
Smoking Status	1.9	4.5	13.9	-1.2	2.0	2.5	-3.7	2.7	2.5	-0.9	0.3
Medication: Atenolol	1.9	2.4	5.1	-1.7	1.9	0.7	-1.0	2.2	1.6	-2.0	1.6
High blood pressure (mother)	1.9	2.7	7.6	-2.8	1.4	1.9	-1.3	1.9	1.1	-1.7	1.2
Heart attack	1.9	2.4	6.4	1.1	-1.5	-1.8	-1.4	-2.0	-0.9	2.5	-1.4
Commuting to job workplace: Car/motor vehicle	1.9	2.2	4.2	-0.6	-1.9	-2.0	-0.6	-1.6	-1.7	1.9	-1.5
Supplements: Calcium	1.9	2.1	5.9	1.5	-1.0	-1.4	-0.8	-0.6	-1.0	2.3	-2.4
Heart attack/myocardial infarction (self-reported)	1.9	2.4	6.4	0.9	-1.5	-1.8	-1.6	-1.9	-1.0	2.5	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.0	8.8	-2.2	-2.1	-2.8	-0.7	-1.5	-3.0	2.7	-0.2
Prospective memory result	1.8	2.2	5.2	-0.9	1.6	2.3	-1.2	1.9	1.1	-1.5	1.7
Hair/balding pattern: Pattern 4	1.8	4.3	10.3	0.5	-2.3	-2.8	3.2	-2.1	-2.3	1.2	-1.8
Asthma (self-reported)	1.8	3.5	8.9	3.0	-1.8	-1.9	2.5	-2.3	-1.7	0.9	-0.6
Wears glasses or contact lenses	1.8	2.0	9.2	3.0	-0.7	-0.3	0.8	-1.7	-1.2	1.2	-1.5
Schizophrenia vs Biploar Disorder	1.7	2.2	7.0	1.1	1.0	1.4	1.2	0.5	1.0	-2.4	2.6
Blood Platelet Count	1.7	19.7	54.0	-3.1	-6.0	-6.5	1.2	-4.9	-7.3	2.4	-2.0
Mouth/teeth dental problems	1.7	2.5	4.9	1.8	1.8	1.6	0.3	1.6	2.0	-2.2	1.7
Pulse rate	1.7	2.9	7.3	-0.3	-2.7	-2.7	1.7	-1.8	-2.1	0.5	-0.8
Happiness	1.7	2.1	5.1	-0.4	2.1	1.3	-0.8	2.2	1.5	-1.7	1.4
Asthma	1.7	3.4	7.4	2.7	-1.9	-1.9	2.2	-2.4	-1.8	1.1	-0.7
Mean time to correctly identify matches	1.7	3.2	8.8	2.3	-2.3	-1.2	1.3	-3.0	-2.1	0.8	-0.8
Qualifications: nursing, teaching	1.7	2.6	5.7	2.4	-0.8	-2.3	1.9	-1.4	0.3	1.6	-2.0
Osteoarthritis (self-reported)	1.7	2.2	5.8	1.9	1.3	0.1	1.5	0.8	1.8	-2.4	1.6
Diabetes (father)	1.6	2.0	5.3	0.3	-2.2	-2.3	0.8	-2.0	-1.4	0.9	-0.9
Impedance of leg (right)	1.6	7.8	15.6	-1.5	3.2	3.9	0.6	2.8	3.9	-3.6	2.4
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.7	9.2	-1.2	-2.1	-2.3	-0.7	-2.0	-3.0	3.0	-0.2
Sitting height	1.6	11.1	58.4	7.6	-2.5	-2.9	3.8	-2.5	-0.4	-1.1	-2.1
Leg fat-free mass (right)	1.6	8.4	21.7	4.7	-2.9	-4.4	0.4	-2.3	-2.0	2.0	-3.5
Leg predicted mass (right)	1.6	8.7	22.8	4.8	-2.9	-4.4	0.4	-2.4	-2.1	2.0	-3.6
Ever had hysterectomy (womb removed)	1.5	1.7	3.1	-1.3	1.7	0.8	0.6	1.8	1.1	-1.8	1.4
High cholesterol (Self-reported)	1.5	2.7	4.9	-1.8	-1.4	-2.2	-1.4	-0.7	-2.1	1.8	-2.0
Risk taking	1.5	2.2	3.9	-0.8	2.0	1.9	-1.9	1.6	1.8	-0.5	1.5
Major Depression (MDD)	1.4	1.6	4.4	-1.4	1.4	0.8	-1.8	2.1	1.4	-0.4	-0.2
Heel T-Score	1.4	10.8	36.4	-6.0	-2.5	-1.9	-2.6	-1.2	-4.4	4.8	-0.7
Ever used hormone-replacement therapy (HRT)	1.4	1.8	5.2	1.8	1.0	0.3	2.3	0.7	1.6	-1.6	0.9
Chronic bronchitis/emphysema (father)	1.4	1.7	10.4	3.2	-0.4	-0.5	1.7	-0.9	-0.4	-0.1	0.6
Trunk fat mass	1.4	5.9	13.1	0.7	3.2	1.8	-1.3	3.6	3.4	-3.1	1.6
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	4.5	0.1	-1.8	-2.1	1.8	-1.7	-1.4	0.9	-0.3
Leg fat percentage (right)	1.4	5.1	10.8	-2.1	2.6	1.9	-2.1	3.3	2.2	-2.5	2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	4.0	0.1	1.5	2.0	-0.6	1.9	1.1	-1.0	1.1
Hearing aid user	1.4	1.6	4.5	0.5	-1.7	-0.7	-0.3	-1.4	-1.7	1.2	-2.1
Mother’s age at death	1.4	1.8	5.8	2.4	-0.7	-1.6	1.5	-1.6	-0.5	0.8	-1.1
Cholesterol lowering medication	1.4	2.0	4.8	-1.4	2.1	0.0	-0.2	2.2	1.2	-1.2	1.9
Neuroticism (2016)	1.3	1.9	4.8	-0.8	1.9	1.4	-0.3	2.2	2.2	-0.5	0.9
Blood White Count	1.3	9.5	21.1	-0.4	-4.4	-4.2	0.6	-3.9	-4.6	2.7	-2.2
Lung FEV1/FVC ratio	1.3	6.7	11.8	-3.3	-2.0	-2.8	-2.5	-1.9	-3.4	3.4	-2.2
Lung FVC	1.3	6.5	24.5	-5.0	1.4	1.4	-4.8	2.8	0.0	0.5	0.2
Medication: Metformin	1.3	1.9	5.2	1.4	-1.4	-2.3	2.0	-1.6	-0.9	-0.2	0.5
Leg fat-free mass (left)	1.3	6.6	19.8	4.5	-2.4	-3.9	-0.0	-1.9	-1.6	1.4	-3.3
Impedance of leg (left)	1.3	6.1	12.7	-1.4	2.8	3.5	1.3	2.4	3.6	-3.0	2.2
Leg predicted mass (left)	1.3	6.7	19.5	4.4	-2.4	-3.9	-0.1	-1.9	-1.6	1.5	-3.4
Illnesses of siblings	1.3	1.8	7.7	0.9	-0.9	-0.6	-1.1	-0.8	-1.1	1.9	-2.8
Peak expiratory flow (PEF)	1.3	3.0	9.7	1.6	-0.8	-1.4	-1.3	-0.9	-0.5	3.1	-3.1
Chest pain or discomfort	1.3	1.8	4.4	0.5	-1.1	-2.1	-0.1	-2.0	-1.3	1.8	-1.2
Unable to work because of sickness or disability	1.3	1.6	3.7	-0.5	-1.5	-0.9	-1.6	-1.9	-1.5	1.6	-0.2
Alzheimer’s Disease (in mother)	1.2	1.4	2.8	0.9	1.4	1.6	0.6	1.2	0.9	-1.5	1.7
Primary Biliary Cirrhosis	1.2	1.6	5.6	0.8	1.8	0.9	-0.4	1.1	2.4	-1.0	1.5
Type 2 Diabetes (T2D) (2018)	1.2	2.2	5.8	1.0	-2.0	-2.4	1.6	-1.9	-1.6	0.3	0.3
Alcohol intake frequency.	1.2	2.9	7.7	-1.2	-0.5	-1.7	2.8	0.4	-1.0	-2.3	2.8
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	4.0	-1.6	0.8	2.0	-1.9	0.8	0.2	-1.0	0.8
Eye problems/disorders: Cataract	1.2	1.4	6.0	-0.8	1.4	1.0	-2.5	1.1	1.3	0.1	-0.7
Worry (Nagel 2018)	1.1	2.4	6.1	-0.8	1.8	0.9	-2.4	2.5	1.9	-0.6	-0.6
Reaction Time	1.1	2.0	6.2	0.9	-2.4	-0.8	-0.2	-2.5	-2.0	0.6	-0.8
Current tobacco smoking	1.1	1.8	10.3	-0.9	0.9	1.1	-3.2	1.3	0.8	0.2	-0.9
Number of incorrect matches in round	1.1	1.8	4.2	-0.2	1.8	2.0	-1.3	1.7	1.3	-1.1	1.3
Qualifications: None of the above	1.1	2.3	6.3	-0.4	1.4	1.7	-0.4	1.3	1.4	-2.4	2.5
Time employed in main current job	1.1	1.3	8.1	1.2	-0.7	-0.9	2.8	-0.4	-0.3	-0.7	0.3
Tense / ‘highly strung’	1.1	1.8	3.9	-0.7	1.7	1.6	-1.3	1.9	2.0	-0.8	0.5
Diabetes diagnosed by doctor	1.1	1.8	6.8	0.1	-1.7	-2.6	1.6	-1.4	-1.5	-0.1	0.2
Smoking status: Current	1.1	1.8	8.0	-0.9	1.2	1.2	-2.8	1.6	1.2	-0.2	-0.5
Number of self-reported non-cancer illnesses	1.1	1.9	6.0	-1.6	1.2	0.5	-0.3	2.0	1.0	-2.4	1.5
Leg fat percentage (left)	1.1	4.1	9.3	-2.1	2.4	1.6	-1.7	3.1	2.0	-2.1	2.0
Blood Eosinophil Count	1.0	7.6	48.7	-7.0	0.1	-0.3	-4.1	0.6	-1.4	0.8	-0.3
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.2	-1.6	0.9	0.8	-1.8	1.5	0.7	-1.1	1.3
Relative age voice broke	1.0	1.5	3.8	-0.4	1.8	0.5	-1.6	1.6	1.9	0.5	-0.9
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.3	1.8	-0.6	-1.5	0.6	-1.2	-0.7	1.3	0.5
Supplements: Glucosamine	1.0	1.2	5.6	2.4	-0.2	-0.6	2.2	-0.5	0.2	-0.0	0.2
Had menopause	1.0	1.2	4.5	1.0	0.7	0.1	2.1	0.6	0.9	-1.3	1.4
Forced vital capacity (FVC)	1.0	3.8	10.1	3.0	-1.2	-2.2	-1.0	-1.1	-0.4	2.6	-3.2
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	10.8	1.6	-1.0	-2.0	-1.6	-0.7	-0.8	2.9	-3.3
Depression (self-reported)	1.0	1.3	4.6	-0.0	-1.2	-1.4	0.8	-0.8	-1.0	2.1	-1.0
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.4	-1.4	-1.2	-1.1	0.7	-1.1	-1.8	1.3	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.9	-0.3	-1.1	-1.0	-0.9	-0.9	-1.4	1.5	-1.7
Guilty feelings	1.0	1.5	3.5	-1.9	1.0	1.0	-1.4	1.5	1.6	-0.8	1.0
Myopia	1.0	1.5	3.8	-1.3	1.9	1.9	-0.4	1.0	1.6	-0.1	-0.6
HDL Cholesterol	0.9	1.5	4.5	-0.6	1.8	0.7	-0.9	1.5	2.1	0.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	3.9	-2.0	-0.9	-1.4	-0.4	-0.5	-1.7	-0.2	0.2
Diabetes (mother)	0.9	1.1	3.5	1.4	-1.1	-1.9	1.0	-1.2	-0.8	0.2	0.3
Townsend deprivation index at recruitment	0.9	1.2	3.6	-0.6	1.4	0.7	-0.3	1.0	1.0	-1.7	1.9
Multivitamins +/- minerals	0.9	1.1	4.2	2.1	-0.0	-1.8	0.7	0.1	0.5	1.1	-0.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	2.8	-1.5	-0.8	1.1	-1.7	0.1	-0.7	1.0	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	3.1	-0.4	-1.3	-1.5	-1.3	-0.8	-1.5	1.8	-1.2
Pain all over the body in last month	0.9	0.9	2.0	0.2	1.4	0.8	-0.7	1.1	1.3	-1.0	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.7	-0.4	1.6	0.9	-0.4	1.6	1.6	-0.3	0.5
Headache pain in last month	0.9	1.6	3.0	-1.7	-1.3	-1.4	-1.6	-0.5	-1.7	1.5	-0.7
Heart disease (mother)	0.9	1.1	3.7	1.4	-1.3	-1.9	0.6	-1.1	-0.7	0.7	-0.6
Whole body fat mass	0.9	3.8	9.9	0.5	2.6	1.2	-1.4	3.2	2.6	-2.3	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	9.4	-3.1	-0.1	0.1	-2.0	0.0	-0.9	1.6	-0.0
Arm fat mass (left)	0.9	3.6	9.3	0.3	2.5	1.1	-2.2	3.0	2.3	-2.1	1.1
Tinnitus: Yes, now most or all of the time	0.9	1.0	1.9	0.4	-1.0	-1.1	1.2	-1.2	-0.8	1.4	-1.1
Medication: Atorvastatin	0.9	1.1	4.1	0.1	-1.1	-2.0	-0.2	-1.7	-0.6	1.1	-0.8
Basal cell carcinoma (self-reported)	0.9	1.1	4.0	-2.0	0.3	0.6	-0.7	1.4	-0.5	-1.1	1.2
Alzheimer’s Disease (including proxy)	0.8	1.1	2.7	1.3	0.8	1.1	0.6	0.6	0.7	-1.6	1.6
Body Mass Index (BMI) (2010)	0.8	1.2	4.9	-1.7	0.4	0.6	-2.2	0.5	-0.7	1.1	-0.1
Vitamin and mineral supplements	0.8	1.1	3.8	-1.9	-0.4	1.6	0.3	-0.4	-0.6	-1.0	1.4
Father’s age at death	0.8	1.0	3.8	1.6	-0.6	-0.9	1.9	-0.9	-0.5	0.8	-0.1
Hair/balding pattern: Pattern 3	0.8	1.2	3.8	-0.2	-1.9	-0.6	0.6	-1.6	-2.0	0.5	-0.2
Arm fat mass (right)	0.8	3.4	8.9	0.6	2.3	1.1	-1.7	3.0	2.2	-2.3	1.3
Exposure to tobacco smoke at home	0.8	0.9	3.4	0.3	-1.3	-0.4	-0.4	-1.1	-1.8	1.0	0.5
Comparative body size at age 10	0.8	2.3	8.2	0.6	-1.0	-1.0	-0.7	-0.6	-1.4	2.9	-2.7
Medication: Aspirin	0.8	1.0	3.9	-0.2	1.3	0.7	0.4	1.3	0.9	-0.9	2.0
Mineral and other dietary supplements	0.8	1.1	8.2	-2.9	-0.6	0.2	-0.1	-0.6	-0.7	0.5	0.1
Medication: Aspirin	0.8	1.1	3.1	0.1	1.5	0.6	0.3	1.4	1.1	-1.0	1.8
Alcohol drinker status: Never	0.8	1.0	4.8	-2.2	0.6	0.6	-0.5	1.3	-0.4	-0.9	0.8
Fractured/broken bones in last 5 years	0.8	1.0	3.2	0.3	0.8	-0.2	1.3	0.8	1.3	-1.8	1.2
Age started oral contraceptive pill	0.8	1.0	4.0	0.3	0.8	0.6	2.0	0.7	0.4	-0.9	1.7
Age at First Birth	0.7	1.0	3.0	0.7	-0.9	-0.7	-1.2	-1.1	-0.8	1.7	-1.1
Triglycerides	0.7	1.2	3.9	-2.0	-1.0	-0.4	-0.8	-0.3	-1.6	-0.1	1.5
Blood Red Count	0.7	6.8	33.8	-5.8	1.4	0.7	-2.5	2.7	-0.3	-1.3	3.0
BMI	0.7	4.2	9.5	-1.7	2.1	0.9	-2.5	3.1	1.2	-2.2	2.7
Number of treatments/medications taken	0.7	1.3	3.5	-1.0	1.2	0.3	-1.0	1.5	0.6	-1.9	1.4
Taking other prescription medications	0.7	1.1	3.6	-1.3	0.7	0.6	-1.9	0.7	-0.0	-1.5	1.1
Serious illness, injury or assault to yourself	0.7	0.8	2.5	0.5	-0.9	-1.6	0.7	-1.0	-0.5	1.3	-0.5
Hearing difficulty/problems with background noise	0.7	1.2	2.1	1.2	-1.0	-1.3	1.1	-1.4	-1.1	1.4	-0.7
Worrier / anxious feelings	0.7	1.3	8.0	-0.7	0.1	0.4	-2.8	0.3	0.3	0.8	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	9.4	1.5	-0.6	-1.4	-1.5	-0.5	0.0	2.1	-3.1
Pulse wave Arterial Stiffness index	0.7	0.8	5.0	0.7	-0.3	0.1	2.2	-0.2	0.1	-1.4	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	2.7	0.6	1.5	-0.2	-0.0	1.6	1.6	-1.1	0.8
Exposure to tobacco smoke outside home	0.7	1.0	3.7	0.3	-1.0	-1.9	1.0	-1.0	-1.0	0.2	0.9
Number of full sisters	0.7	0.9	2.6	0.2	-1.4	-1.6	-0.9	-1.0	-1.1	0.5	-0.2
Had major operations	0.7	0.8	2.8	0.2	0.5	0.2	1.7	0.6	0.8	-1.6	1.0
Leg pain on walking	0.7	0.8	1.7	1.3	-1.3	-0.4	1.0	-1.3	-1.0	-0.6	-0.1
Supplements: Vitamin C	0.7	0.8	2.1	1.3	0.3	-0.7	-1.4	-0.0	0.2	0.7	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.2	-0.7	-1.1	-0.5	0.3	-0.7	-1.8	1.2	-0.1
Commuting to job workplace: Walk	0.7	0.8	3.9	1.1	0.2	0.7	1.0	0.0	0.6	0.3	-2.0
Miserableness	0.7	1.2	5.5	-2.4	-0.2	-0.2	-2.0	0.3	-0.2	1.0	-0.4
Ever depressed for a whole week	0.7	0.9	2.4	-1.3	1.1	0.2	-1.5	1.4	1.0	0.1	-0.1
Depression (Nagel 2018)	0.6	0.9	4.8	-1.4	-0.1	-0.0	-2.2	0.7	-0.3	-0.0	0.5
Alzheimer’s Disease (in father)	0.6	0.6	1.9	0.4	-1.4	-0.7	0.7	-1.3	-0.8	-0.1	-0.5
Prostate Cancer	0.6	0.8	3.2	1.1	-0.3	-1.8	1.4	0.4	0.1	-0.1	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	4.3	-1.8	-0.1	0.1	-2.1	0.7	-0.0	0.5	-0.4
Medication: Lansoprazole	0.6	0.7	2.9	-1.7	-0.7	-0.9	-0.8	-0.1	-0.9	0.9	-0.0
Forced vital capacity (FVC), Best measure	0.6	2.1	7.3	2.4	-0.5	-1.4	-0.9	-0.5	0.5	1.5	-2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.5	-0.1	0.7	0.8	1.2	1.1	1.1	-1.2	0.8
Wheeze or whistling in the chest in last year	0.6	1.0	3.0	1.7	0.9	-0.2	0.9	0.5	1.3	-1.2	1.0
Pulse wave peak to peak time	0.6	0.7	3.4	0.1	0.1	-0.5	-1.9	-0.0	-0.1	1.5	-0.3
Shortness of breath walking on level ground	0.6	0.7	1.8	-0.0	-0.8	-1.1	0.2	-1.0	-0.9	1.4	-0.3
Eye problems/disorders: None of the above	0.6	0.6	1.7	0.4	-1.3	-0.5	1.0	-1.3	-0.9	0.7	-0.2
Mood swings	0.6	1.2	2.6	-0.5	-1.1	-1.2	-1.1	-0.1	-1.3	1.6	-1.4
Long-standing illness, disability or infirmity	0.6	0.9	2.8	-0.7	0.2	-1.2	-0.1	0.5	0.3	-1.7	1.6
Friendships satisfaction	0.6	0.7	3.2	0.7	0.5	1.2	-1.8	0.2	0.6	0.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	4.7	-2.2	-0.4	-0.5	-1.7	0.3	-0.7	0.2	-0.4
Medication: Gliclazide	0.6	0.7	2.7	0.7	-0.1	0.0	0.8	0.5	-0.5	-1.3	1.6
Average weekly champagne plus white wine intake	0.6	0.9	2.9	0.1	1.1	1.7	0.5	0.9	1.4	-0.7	-0.5
Heart disease (siblings)	0.6	0.7	1.9	0.4	-0.8	-1.2	1.0	-1.4	0.1	0.6	0.8
Depressed Affect (Nagel 2018)	0.5	1.1	4.8	-0.6	-1.0	-0.4	-2.2	-0.2	-1.2	1.4	-0.7
Neuroticism (Nagel 2018)	0.5	1.2	7.0	-0.9	0.2	0.4	-2.6	0.9	0.4	1.0	-1.0
Rheumatoid Arthritis	0.5	0.7	2.0	1.4	0.0	-1.0	1.0	-0.0	0.3	1.3	-1.0
Average weekly spirits intake	0.5	0.6	3.0	0.0	-0.4	-0.2	-1.7	-0.2	-1.0	0.6	-1.0
Sensitivity / hurt feelings	0.5	0.9	2.7	-1.5	0.1	-0.1	-0.9	0.6	0.8	1.2	-1.6
Hearing difficulty/problems: Yes	0.5	0.7	2.5	1.4	-0.7	-0.4	1.6	-0.4	-0.5	0.6	-0.6
Pack years adult smoking proportion	0.5	0.7	4.2	-2.1	0.4	1.2	-0.5	0.3	0.1	-0.2	0.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.8	1.0	0.2	-1.0	1.4	-0.0	0.7	0.5	-0.6
Qualifications: CSEs or equivalent	0.5	0.7	3.1	-0.9	0.3	-0.1	-1.8	1.2	0.1	-0.1	0.8
Diabetes (self-reported)	0.5	0.8	4.1	-0.1	-1.0	-2.0	1.0	-0.9	-0.6	-0.4	0.3
Medication: Ramipril	0.5	0.6	1.5	-0.8	0.9	0.7	-0.6	1.1	1.2	-0.5	-0.4
Hip circumference	0.5	2.3	5.5	1.5	2.0	0.5	-1.2	2.3	2.1	-1.6	0.1
Falls in the last year	0.5	0.7	3.2	-1.5	0.2	0.1	-1.8	0.5	-0.1	0.2	0.4
Breastfed as a baby	0.5	0.6	2.6	-1.6	0.2	-0.7	-0.4	0.6	0.2	-1.1	0.7
Mouth/teeth dental problems: Loose teeth	0.5	0.7	3.4	-1.9	-0.4	-0.0	-0.8	-0.4	-0.7	1.0	0.0
Emphysema/chronic bronchitis	0.5	0.5	2.2	0.8	0.1	-0.4	1.1	0.1	0.3	-1.5	0.8
Suffer from ‘nerves’	0.5	0.7	3.3	-0.2	-0.1	-0.4	-1.8	0.4	0.2	1.0	-1.4
Knee pain experienced in last month	0.5	0.8	2.2	-0.5	0.5	0.4	-0.6	0.8	1.0	-1.4	1.5
Average weekly red wine intake	0.5	0.8	2.2	1.3	0.3	-1.5	-0.1	-0.5	0.8	1.0	-1.2
Alcohol drinker status: Previous	0.5	0.5	1.7	-1.3	0.2	-1.3	0.1	0.3	0.2	-0.7	0.9
Schizophrenia (2018)	0.4	0.8	3.9	0.7	1.1	0.6	0.1	0.4	0.7	-0.8	2.0
Crohns Disease (2017)	0.4	0.9	1.7	1.2	-1.2	-0.5	-1.3	-1.3	-1.1	0.7	0.5
Ulcerative Colitis (UC)	0.4	0.7	2.9	-1.1	0.2	1.2	-1.7	0.1	-0.6	0.4	0.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	4.9	-2.2	0.3	-0.5	-0.1	0.8	0.8	1.1	-1.1
Fasting Glucose	0.4	0.5	1.4	0.4	-1.2	-1.0	-0.3	-0.8	-1.1	0.0	-0.3
LDL Cholesterol	0.4	0.6	2.4	-0.9	-0.3	-0.9	0.7	-0.0	-1.0	0.0	1.5
Ulcerative Colitis	0.4	0.5	1.5	-0.2	-0.0	1.1	-1.2	-0.3	-0.9	0.8	-0.6
Allergy or Eczema	0.4	1.1	6.1	2.5	-0.8	-0.3	0.6	-1.4	-0.1	0.8	0.2
Neuroticism	0.4	1.1	3.5	-1.2	0.5	0.5	-1.9	1.6	0.8	0.3	-0.9
Maternal smoking around birth	0.4	0.6	1.8	0.9	-0.9	-0.5	-1.1	-0.3	-0.7	1.3	-0.2
Fed-up feelings	0.4	0.7	3.0	-1.4	-0.2	-0.4	-1.7	1.0	-0.3	0.5	0.5
Age when periods started (menarche)	0.4	1.0	3.2	-1.2	0.2	-0.1	0.9	0.6	0.4	-1.6	1.8
Hair/balding pattern: Pattern 2	0.4	0.6	2.8	0.6	0.8	-0.4	-0.1	0.9	0.4	-0.3	1.7
Allergy	0.4	1.0	5.3	-2.3	0.6	0.1	-0.6	1.1	0.1	0.7	-1.0
Neuroticism score	0.4	0.8	2.0	-1.4	-0.3	-0.8	-1.2	0.6	0.0	1.3	-1.2
Weight	0.4	2.1	13.0	3.6	-0.3	-1.9	0.1	0.2	0.4	-0.5	-1.2
Mouth/teeth dental problems: Dentures	0.4	0.7	1.8	0.1	-0.9	-1.1	0.5	-1.2	-0.5	1.4	-0.3
Lung cancer (father)	0.4	0.4	1.6	-0.2	0.6	0.0	1.3	0.6	0.8	-0.7	0.5
Pulse wave reflection index	0.4	0.5	2.1	-0.5	0.6	1.5	-0.3	0.7	0.8	0.0	-0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.2	1.5	-0.1	-0.1	0.9	-0.3	-0.1	1.4	-0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.7	-0.5	1.0	1.1	-0.9	1.2	0.8	-1.3	0.7
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.0	0.6	0.8	0.1	0.0	0.9	1.0	-0.9	0.7
Neck or shoulder pain in last month	0.4	0.6	1.3	1.0	0.7	0.8	-1.1	0.4	1.1	0.3	0.0
Migraine (self-reported)	0.4	0.5	2.7	-1.6	-0.3	-1.0	-0.2	-0.0	-0.6	0.1	-0.5
Comparative height size at age 10	0.4	2.3	6.6	2.6	-2.1	-1.8	1.4	-1.6	-0.8	-0.0	-1.1
Loneliness, isolation	0.4	0.6	1.5	-0.7	-1.0	-0.4	-1.1	-0.5	-0.7	1.2	-0.6
Ever had bowel cancer screening	0.4	0.4	1.2	0.7	0.7	0.5	-0.7	-0.0	1.0	-1.1	0.5
Back pain experienced in last month	0.4	0.5	2.1	1.4	-0.7	-0.9	-0.3	-1.0	-0.3	0.2	-0.3
Breast cancer (self-reported)	0.4	0.4	1.0	0.2	-0.6	-0.7	1.0	-0.3	-0.0	0.9	-1.0
Eye problems/disorders: Glaucoma	0.4	0.5	1.7	-0.7	-0.2	1.0	-1.3	-0.2	-0.8	-0.2	0.6
Supplements: Fish oil (including cod liver oil)	0.4	0.6	2.5	1.6	0.8	0.3	-0.5	0.7	0.6	-0.5	0.8
Average weekly beer plus cider intake	0.4	0.6	2.6	1.6	-0.6	-1.1	0.7	-0.7	-0.1	0.2	0.4
Pack years of smoking	0.4	0.7	3.3	-1.8	0.5	1.3	-0.2	0.4	0.2	-0.5	0.3
Bipolar Disorder or Schizophrenia	0.3	0.8	4.0	-0.4	-0.3	-0.8	-1.0	-0.9	-0.6	2.0	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.6	-1.3	-0.1	-0.3	-1.1	0.2	0.2	1.4	-1.6
Irritable Bowel Disease (IBD)	0.3	0.8	4.2	-0.0	-0.6	0.6	-2.0	-0.7	-0.9	0.9	0.3
Breast Cancer	0.3	0.6	3.3	1.8	0.6	-0.1	0.3	-0.0	0.8	0.3	1.1
Crohns Disease (2012)	0.3	0.4	1.5	1.2	-0.3	0.1	-1.0	-0.6	0.1	0.8	-0.3
Medication for hormone replacement therapy	0.3	0.4	1.3	1.1	0.4	0.2	-0.1	0.3	1.0	-0.2	-0.9
Supplements: Zinc	0.3	0.4	1.7	1.3	-0.5	-1.0	-0.3	-0.0	-0.1	-0.1	-0.4
Severe depression (siblings)	0.3	0.3	1.3	0.1	-0.5	-0.9	-0.4	-0.1	-1.1	0.6	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.5	-1.2	-0.3	-0.5	-1.2	0.2	-0.0	-0.0	0.3
Body mass index (BMI)	0.3	1.1	3.6	-1.1	0.9	-0.1	-1.9	1.9	0.3	-0.6	0.8
Past tobacco smoking	0.3	0.5	2.4	-0.2	-0.0	0.0	1.6	0.1	-1.2	-0.6	0.2
Nervous feelings	0.3	0.6	2.6	-0.2	0.9	0.7	-1.6	0.9	0.9	-0.2	0.3
Medication: Simvastatin	0.3	0.5	2.3	-1.5	0.1	-0.3	-0.3	0.9	-0.6	-0.5	0.6
Fluid intelligence score	0.3	0.7	3.0	-1.7	-0.8	-0.8	-0.4	-0.4	-0.2	1.1	-0.7
Noisy workplace	0.3	0.4	1.2	-0.8	0.5	-0.4	-0.6	0.5	0.4	-0.5	1.1
Health satisfaction	0.3	0.3	1.0	0.3	-0.7	-0.2	1.0	-0.8	-0.3	0.1	-0.8
Qualifications: College or University degree	0.3	0.9	2.1	0.8	1.4	0.7	1.5	0.3	1.2	-0.3	-0.9
Medication for pain relief, constipation, heartburn	0.3	0.5	2.3	-0.6	-0.2	-0.5	-0.3	-0.8	0.4	0.6	-1.5
Medication: Ibuprofen	0.3	0.4	1.8	0.8	-0.5	-0.7	-0.6	-0.1	-1.4	0.2	0.3
Leg fat mass (right)	0.3	1.1	3.7	0.4	1.2	0.2	-1.1	1.9	1.3	-1.4	0.4
Age at last live birth	0.3	0.4	1.1	0.7	0.6	0.8	0.7	0.5	1.1	0.0	-0.3
Illnesses of father: Heart disease	0.3	0.4	1.1	-0.2	-0.1	-1.1	-0.8	0.4	-0.1	1.0	-0.8
Financial situation satisfaction	0.3	0.3	2.2	-0.3	0.6	0.1	-1.5	0.3	0.4	0.4	-0.1
Commuting to job workplace: Public transport	0.3	0.3	1.9	0.7	0.0	1.4	-0.3	-0.4	0.3	-0.1	-0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.8	0.6	0.2	0.6	0.1	-0.1	0.5	-1.3	0.9
Medication: Paracetamol	0.3	0.4	1.2	1.0	-1.1	-0.1	-0.1	-0.8	-1.0	0.4	0.2
Ever smoked	0.3	0.6	1.7	1.0	-0.3	-0.8	-1.3	-0.2	0.8	0.9	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	-1.0	0.5	0.3	-0.2	0.4	0.3	-0.0	-1.0
Pain experienced in last month	0.3	0.5	2.2	-0.9	-0.5	-0.1	1.5	-0.3	-1.2	-0.3	0.2
Leg fat mass (left)	0.3	1.1	3.9	0.4	1.2	0.2	-0.9	2.0	1.4	-1.3	0.5
Ovarian Cancer	0.2	0.3	0.6	-0.4	0.3	-0.8	-0.8	0.6	0.5	0.5	-0.5
Coronary Artery Disease (CAD)	0.2	0.2	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.4
Schizophrenia (2014)	0.2	0.3	1.0	0.3	-0.0	-0.2	-0.5	-0.8	-0.3	1.0	0.9
Angina	0.2	0.3	0.7	0.3	-0.4	-0.7	0.1	-0.7	-0.2	0.9	-0.7
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.6	1.6	-0.2	0.1	-0.4	-0.7	0.2	-0.2	0.5
Waist circumference	0.2	0.9	3.3	1.6	-0.6	-1.8	0.5	-0.4	-0.4	-0.9	0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.0	-1.0	0.2	-0.1	-0.6	0.5	0.4	0.5	-0.1
Financial difficulties in last 2 years	0.2	0.2	0.5	-0.5	-0.2	-0.6	-0.7	-0.6	-0.2	0.1	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.2	0.8	-0.4	-0.6	-0.3	-0.1	-1.1	0.4	0.0
Illnesses of mother	0.2	0.2	0.9	-0.4	0.2	0.0	-1.0	0.0	0.2	0.3	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.1	-0.1	-0.6	-0.2	-0.9	0.1	-0.4	1.0	-0.3
Glaucoma (self-reported)	0.2	0.2	0.7	-0.8	-0.2	0.4	-0.7	-0.2	-0.6	-0.4	0.1
Number of full brothers	0.2	0.3	0.7	0.2	0.8	0.6	-0.8	0.4	0.4	-0.4	0.6
Worry too long after embarrassment	0.2	0.4	1.2	0.1	-0.3	-0.1	0.6	-0.8	0.3	1.1	-0.9
Number of children fathered	0.2	0.2	1.2	0.3	0.1	-0.2	0.4	0.1	0.3	0.1	-1.1
Age at first live birth	0.2	0.4	1.2	0.3	0.6	0.6	1.1	0.6	1.0	-0.7	0.0
Angina (self-reported)	0.2	0.3	1.0	0.3	-0.3	-0.5	-0.1	-0.7	-0.2	1.0	-0.9
Medication: Omeprazole	0.2	0.2	1.0	0.7	-0.0	-0.0	1.0	-0.5	0.0	-0.5	-0.3
Overall health rating	0.2	0.5	1.6	-0.1	-0.8	-0.7	-1.0	-1.3	-0.5	0.2	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.6	0.5	-0.5	-0.5	0.8	-0.0	0.6	0.5	-0.2
Smoking status: Previous	0.2	0.3	2.2	0.3	0.2	0.3	-0.2	-0.0	1.5	-0.2	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.3	1.1	-0.3	-0.2	0.7	-0.4	-0.4	-0.5	-0.2
Osteoporosis (self-reported)	0.2	0.3	0.9	0.0	1.0	0.6	-0.1	0.8	0.6	0.0	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	1.6	-0.1	0.2	0.4	1.3	-0.3	-0.0	0.2	0.3
Commuting to job workplace: Cycle	0.2	0.3	1.0	-0.6	0.2	-0.4	0.5	-0.2	0.6	0.5	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.5	0.4	0.0	-0.5	1.2	-0.2	0.1	-0.1	-0.4
Bipolar Disorder (2011)	0.1	0.1	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.7
Mean Putamen Volume	0.1	0.1	0.3	0.4	-0.2	-0.5	0.0	-0.1	0.1	0.0	-0.4
Hypothyroidism (self reported)	0.1	0.3	0.9	0.0	0.8	0.8	-0.4	0.6	1.0	-0.6	0.3
Chronotype (morning person)	0.1	0.2	1.0	-0.1	0.5	1.0	-0.2	0.4	-0.2	0.1	-0.0
Hair Pigment	0.1	2.7	12.6	-0.8	1.0	1.4	0.6	0.9	1.3	-3.5	2.2
Average weekly fortified wine intake	0.1	0.1	0.5	-0.3	-0.2	-0.3	-0.5	-0.4	-0.7	0.2	-0.3
Medication: Levothyroxine sodium	0.1	0.1	0.3	-0.2	0.2	0.4	-0.6	0.3	0.2	-0.5	0.2
Loud music exposure frequency	0.1	0.1	0.3	0.0	-0.0	0.6	-0.3	0.3	0.2	0.4	0.2
Medication: Paracetamol	0.1	0.2	1.0	0.1	-0.2	0.4	-0.5	0.1	-0.5	-0.2	1.0
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.5	-0.2	0.7	0.1	-0.3	0.1	0.2	-0.6	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	0.3	0.3	0.2	-0.7	-0.6	0.3	0.1	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.5	-0.4	-0.1	-0.2	0.3	0.2	0.4	-0.5
Tanning	0.0	0.6	1.8	-1.4	-0.7	0.6	-0.9	-0.2	-0.8	0.4	-0.9
Medication: Seretide 50 evohaler	0.0	0.0	0.2	-0.0	-0.1	-0.1	0.3	-0.0	-0.1	-0.4	0.2

Hub : Genes

TNFSF12

Models

Trait associations