Best TWAS P=1.06e-08 · Best GWAS P=1e-07 conditioned to 0.106
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | RP11-810M2.2 | 0.30 | 0.02 | lasso | 4 | 0.02 | 8.5e-02 | 5.3 | 5.4 | 6.3e-08 | 0.91 | 0.02 | 0.81 | TRUE |
| 2 | GTEx | Brain Putamen basal ganglia | AC012146.7 | 0.30 | 0.03 | enet | 23 | 0.03 | 7.6e-02 | 3.9 | -5.7 | 1.1e-08 | 0.05 | 0.06 | 0.18 | TRUE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | GP1BA | 0.35 | 0.16 | lasso | 11 | 0.18 | 5.9e-07 | 4.1 | 5.4 | 5.5e-08 | -0.02 | 0.07 | 0.83 | FALSE |
| 4 | GTEx | Muscle Skeletal | ZZEF1 | 0.11 | 0.01 | lasso | 3 | 0.01 | 1.9e-02 | 5.1 | 5.1 | 2.9e-07 | 0.95 | 0.02 | 0.95 | FALSE |