Best TWAS P=5.39e-08 · Best GWAS P=1.16e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | THAP3 | 0.22 | 0.19 | lasso | 5 | 0.22 | 3.1e-10 | 4.4 | 5.2 | 2.0e-07 | -0.72 | 0.25 | 0.74 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | THAP3 | 0.05 | 0.04 | blup | 51 | 0.05 | 4.4e-06 | -5.0 | 5.4 | 5.4e-08 | -0.96 | 0.01 | 0.99 | TRUE |