[Hub]/) : Traits : Body fat percentage :

chr1:7,715,776-9,571,422

Best TWAS P=3.84e-11 · Best GWAS P=2.2e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RERE 0.20 0.23 lasso 2 0.24 1.7e-19 5.7 6.2 5.0e-10 -0.77 0.05 0.95 FALSE
2 GTEx Adipose Subcutaneous RP5-1115A15.1 0.14 0.07 enet 20 0.10 2.6e-08 -6.3 5.9 2.9e-09 -0.88 0.00 1.00 FALSE
3 GTEx Adipose Visceral Omentum RERE 0.22 0.17 lasso 5 0.17 5.2e-09 -5.9 5.6 2.6e-08 -0.90 0.01 0.99 FALSE
4 GTEx Breast Mammary Tissue RERE 0.19 0.08 enet 10 0.14 8.0e-08 5.9 5.3 1.4e-07 -0.71 0.05 0.94 FALSE
5 GTEx Breast Mammary Tissue RP5-1115A15.1 0.10 0.07 lasso 2 0.03 7.0e-03 5.7 5.7 1.3e-08 -0.64 0.03 0.95 FALSE
6 GTEx Cells Transformed fibroblasts RERE 0.12 0.08 lasso 4 0.05 6.0e-05 5.9 6.0 2.6e-09 -0.67 0.03 0.97 FALSE
7 GTEx Esophagus Mucosa RERE 0.13 0.16 lasso 3 0.16 7.2e-11 -5.9 5.9 2.8e-09 -0.98 0.01 0.99 FALSE
8 GTEx Esophagus Mucosa RP5-1115A15.1 0.06 0.06 lasso 4 0.05 3.0e-04 -5.9 6.1 8.3e-10 -0.95 0.01 0.97 FALSE
9 GTEx Lung RERE 0.07 0.05 lasso 4 0.05 2.0e-04 -5.5 5.6 1.9e-08 -0.87 0.06 0.93 FALSE
10 GTEx Lung RP5-1115A15.1 0.05 0.08 lasso 1 0.07 1.0e-05 -6.3 6.3 3.5e-10 -1.00 0.00 1.00 FALSE
11 GTEx Muscle Skeletal RP5-1115A15.1 0.09 0.07 enet 10 0.06 1.5e-06 -5.9 5.1 3.0e-07 -0.87 0.00 1.00 FALSE
12 GTEx Pancreas RERE 0.11 0.12 lasso 4 0.07 5.9e-04 5.9 5.8 9.2e-09 -0.64 0.02 0.93 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RP5-1115A15.1 0.08 0.04 enet 8 0.04 3.0e-03 -5.4 5.7 1.4e-08 -0.95 0.02 0.94 FALSE
14 GTEx Skin Sun Exposed Lower leg RP5-1115A15.1 0.07 0.03 enet 13 0.03 1.5e-03 -5.9 5.1 2.9e-07 -0.87 0.01 0.98 FALSE
15 GTEx Thyroid RP5-1115A15.1 0.09 0.12 lasso 2 0.09 1.5e-07 -6.3 6.3 2.2e-10 -0.99 0.00 1.00 FALSE
16 GTEx Whole Blood RERE 0.19 0.15 lasso 4 0.13 2.7e-12 -5.9 6.1 1.1e-09 -0.98 0.01 0.99 FALSE
17 METSIM Adipose RERE 0.08 0.12 lasso 17 0.13 1.8e-19 5.6 5.9 3.5e-09 -0.80 0.08 0.92 FALSE
18 NTR Blood RERE 0.04 0.04 lasso 8 0.03 2.0e-11 -5.3 5.5 4.9e-08 -0.88 0.09 0.91 FALSE
19 ROSMAP Brain Pre-frontal Cortex RERE 0.15 0.15 lasso 7 0.15 1.5e-18 5.8 6.0 1.7e-09 -0.73 0.05 0.95 FALSE
20 YFS Blood RERE 0.09 0.15 lasso 4 0.16 5.7e-49 -6.3 6.6 3.8e-11 -0.98 0.00 1.00 TRUE
21 The Cancer Genome Atlas Breast Invasive Carcinoma RERE 0.02 0.03 lasso 2 0.03 4.7e-07 -6.3 6.2 4.5e-10 -0.98 0.00 1.00 FALSE
22 The Cancer Genome Atlas Pancreatic Adenocarcinoma RERE 0.22 0.04 lasso 10 0.08 4.1e-04 -5.9 6.5 6.4e-11 -0.90 0.01 0.97 FALSE