Best TWAS P=4.78e-09 · Best GWAS P=1.05e-11 conditioned to 2.79e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | ZMYND12 | 0.18 | 0.01 | enet | 22 | 0.04 | 3.9e-02 | -5.4 | -5.8 | 4.8e-09 | -0.31 | 0.07 | 0.14 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RIMKLA | 0.06 | 0.06 | bslmm | 341 | 0.05 | 1.3e-07 | -3.4 | 5.8 | 9.0e-09 | 0.16 | 0.98 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RIMKLA | 0.03 | 0.02 | blup | 53 | 0.01 | 2.8e-02 | 4.2 | 5.3 | 9.1e-08 | 0.23 | 0.00 | 0.36 | TRUE |