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chr10:133,309,117-135,192,153

Best TWAS P=2.46e-10 · Best GWAS P=3.74e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DPYSL4	0.09	0.03	enet	16	0.05	9.9e-07	6.5	5.2	2.0e-07	0.80	0.00	1.00	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	DPYSL4	0.51	0.20	enet	67	0.18	2.0e-06	6.3	5.2	1.8e-07	0.72	0.01	0.98	FALSE
3	GTEx	Cells Transformed fibroblasts	DPYSL4	0.53	0.39	enet	14	0.58	1.1e-52	6.5	5.4	8.1e-08	0.88	0.00	1.00	FALSE
4	GTEx	Pituitary	DPYSL4	0.24	0.11	lasso	4	0.26	3.0e-07	3.7	5.8	5.8e-09	0.63	0.02	0.81	FALSE
5	GTEx	Testis	STK32C	0.46	0.42	lasso	6	0.42	3.4e-20	4.6	-5.2	2.2e-07	-0.09	0.99	0.01	TRUE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	DPYSL4	0.19	0.30	enet	19	0.37	3.1e-79	6.3	5.2	2.5e-07	0.89	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DPYSL4	0.31	0.19	lasso	10	0.18	3.4e-09	6.3	6.0	2.4e-09	0.91	0.00	1.00	FALSE
8	The Cancer Genome Atlas	Glioblastoma Multiforme	STK32C	0.13	-0.01	blup	107	0.08	1.6e-03	3.2	-6.1	1.1e-09	-0.35	0.04	0.07	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DPYSL4	0.16	0.21	enet	16	0.24	7.1e-27	6.3	5.6	2.2e-08	0.91	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DPYSL4	0.17	0.24	lasso	3	0.23	2.4e-13	6.5	6.3	2.5e-10	0.98	0.00	1.00	TRUE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	DPYSL4	0.13	0.12	lasso	7	0.16	3.1e-17	6.5	5.9	3.8e-09	0.93	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DPYSL4	0.13	0.11	enet	7	0.08	2.0e-04	6.3	6.3	3.2e-10	0.96	0.02	0.97	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	DPYSL4	0.17	0.16	enet	18	0.23	1.5e-26	6.6	5.7	1.2e-08	0.86	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	GPR123	0.05	0.00	blup	56	0.02	8.0e-04	3.6	6.0	1.7e-09	0.00	0.00	0.17	TRUE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	DPYSL4	0.34	0.37	enet	15	0.46	2.2e-53	-5.8	5.5	2.8e-08	0.92	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Skin Cutaneous Melanoma	DPYSL4	0.27	0.07	blup	64	0.07	7.1e-03	6.3	5.2	1.5e-07	0.88	0.01	0.73	FALSE
17	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DPYSL4	0.17	0.12	blup	64	0.11	1.3e-04	-5.6	5.2	2.2e-07	0.85	0.02	0.96	FALSE