Best TWAS P=7.71e-09 · Best GWAS P=6.36e-11 conditioned to 0.00389
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | STK33 | 0.18 | 0.18 | lasso | 9 | 0.20 | 3.8e-24 | -4.7 | 5.7 | 1.3e-08 | -0.83 | 0.87 | 0.13 | TRUE |
| 2 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | -5.4 | -5.6 | 2.3e-08 | 0.02 | 0.05 | 0.72 | FALSE |
| 3 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | -5.3 | 5.3 | 1.3e-07 | -0.03 | 0.07 | 0.82 | FALSE |
| 4 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | -5.3 | 5.5 | 2.8e-08 | -0.02 | 0.22 | 0.78 | FALSE |
| 5 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -5.3 | 5.8 | 7.7e-09 | -0.04 | 0.61 | 0.39 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | STK33 | 0.14 | 0.08 | lasso | 6 | 0.10 | 1.0e-09 | -5.0 | 5.5 | 3.4e-08 | -0.66 | 0.65 | 0.35 | FALSE |