[Hub]/) : Traits : Whole body fat mass :

chr10:133,309,117-135,192,153

Best TWAS P=6.02e-11 · Best GWAS P=9.69e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DPYSL4 0.09 0.03 enet 16 0.05 9.9e-07 6.8 5.4 5.3e-08 0.80 0.00 1.00 FALSE
2 GTEx Cells Transformed fibroblasts DPYSL4 0.53 0.39 enet 14 0.58 1.1e-52 6.8 5.4 6.5e-08 0.88 0.00 1.00 FALSE
3 GTEx Pituitary DPYSL4 0.24 0.11 lasso 4 0.26 3.0e-07 3.6 5.9 3.5e-09 0.63 0.02 0.81 FALSE
4 GTEx Testis STK32C 0.46 0.42 lasso 6 0.42 3.4e-20 4.4 -5.2 2.6e-07 -0.09 1.00 0.00 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma DPYSL4 0.19 0.30 enet 19 0.37 3.1e-79 6.5 5.4 8.5e-08 0.89 0.01 0.99 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DPYSL4 0.31 0.19 lasso 10 0.18 3.4e-09 6.5 6.2 5.0e-10 0.91 0.00 1.00 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme STK32C 0.13 -0.01 blup 107 0.08 1.6e-03 2.9 -6.0 2.3e-09 -0.35 0.04 0.07 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DPYSL4 0.16 0.24 blup 60 0.27 7.6e-31 -5.9 5.3 1.5e-07 0.91 0.02 0.98 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPYSL4 0.16 0.21 enet 16 0.24 7.1e-27 6.5 5.7 1.4e-08 0.91 0.00 1.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DPYSL4 0.17 0.24 lasso 3 0.23 2.4e-13 6.8 6.5 6.0e-11 0.98 0.00 1.00 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma DPYSL4 0.13 0.12 lasso 7 0.16 3.1e-17 6.8 6.0 2.1e-09 0.93 0.00 1.00 FALSE
12 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DPYSL4 0.13 0.11 enet 7 0.08 2.0e-04 6.5 6.5 7.2e-11 0.96 0.01 0.97 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma DPYSL4 0.17 0.16 enet 18 0.23 1.5e-26 6.8 5.7 1.2e-08 0.86 0.00 1.00 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma GPR123 0.05 0.00 blup 56 0.02 8.0e-04 3.7 6.2 7.2e-10 0.00 0.00 0.26 TRUE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DPYSL4 0.24 0.21 lasso 7 0.28 2.5e-19 6.5 5.3 1.0e-07 0.84 0.00 1.00 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma DPYSL4 0.34 0.37 enet 15 0.46 2.2e-53 -5.9 5.7 1.3e-08 0.92 0.01 0.99 FALSE
17 The Cancer Genome Atlas Skin Cutaneous Melanoma DPYSL4 0.27 0.07 blup 64 0.07 7.1e-03 6.5 5.4 8.5e-08 0.88 0.01 0.73 FALSE
18 The Cancer Genome Atlas Testicular Germ Cell Tumors DPYSL4 0.17 0.12 blup 64 0.11 1.3e-04 -5.9 5.4 7.8e-08 0.85 0.02 0.96 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma DPYSL4 0.30 0.24 enet 15 0.38 1.7e-38 2.2 5.3 1.5e-07 0.77 0.01 0.99 FALSE