TWAS
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Usage
Models
Genes
Traits
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Traits
:
Whole body fat mass
:
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chr22:17,414,103-18,655,860
Best TWAS P=4.81e-09 · Best GWAS P=4.63e-09 conditioned to 0.0334
17.4M
17.6M
17.8M
18M
18.2M
18.4M
18.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
YFS
Blood
BCL2L13
0.08
0.07
bslmm
544
0.10
1.6e-30
5.1
5.9
4.8e-09
0.77
0.02
0.98
TRUE
1
CommonMind
Brain Pre-frontal Cortex
BCL2L13
0.19
0.09
lasso
13
0.12
5.9e-15
5.9
-5.8
7.5e-09
-0.88
0.00
1.00
FALSE
2
GTEx
Artery Tibial
BID
0.15
0.07
enet
21
0.07
6.3e-06
5.1
-5.4
5.8e-08
-0.83
0.01
0.99
FALSE
3
GTEx
Brain Cortex
BID
0.25
0.19
lasso
7
0.12
3.4e-04
5.0
-5.3
1.3e-07
-0.89
0.03
0.91
FALSE
5
The Cancer Genome Atlas
Testicular Germ Cell Tumors
BID
0.16
-0.01
blup
70
0.06
5.1e-03
5.0
-5.3
1.5e-07
-0.75
0.00
0.92
FALSE