[Hub]/) : Traits : Whole body fat mass : ← →

chr22:37,528,576-39,663,066

Best TWAS P=1.81e-14 · Best GWAS P=5.86e-15 conditioned to 0.0821

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	BAIAP2L2	0.11	0.03	lasso	5	0.04	1.8e-04	6.0	-7.0	2.1e-12	-0.71	0.02	0.91	FALSE
2	GTEx	Adipose Subcutaneous	TMEM184B	0.08	0.08	lasso	4	0.07	1.0e-06	5.0	-5.9	2.8e-09	-0.59	0.81	0.15	FALSE
3	GTEx	Artery Aorta	C22orf23	0.10	0.01	enet	24	0.02	1.6e-02	2.8	6.0	1.7e-09	0.34	0.26	0.09	FALSE
4	GTEx	Artery Aorta	PLA2G6	0.10	0.02	enet	9	0.02	4.5e-02	4.9	7.4	1.3e-13	0.68	0.08	0.54	FALSE
5	GTEx	Artery Aorta	TMEM184B	0.17	0.07	enet	34	0.03	1.2e-02	7.0	-6.9	4.4e-12	-0.68	0.07	0.69	FALSE
6	GTEx	Artery Aorta	AL021977.1	0.13	0.00	enet	17	0.01	8.7e-02	7.0	-7.7	1.8e-14	-0.73	0.04	0.70	TRUE
7	GTEx	Brain Cortex	TMEM184B	0.29	0.12	lasso	7	0.09	1.6e-03	7.0	-7.3	3.4e-13	-0.91	0.01	0.89	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	PLA2G6	0.28	0.17	enet	13	0.18	1.3e-06	-5.9	6.8	9.6e-12	0.69	0.32	0.49	FALSE
9	GTEx	Cells Transformed fibroblasts	ANKRD54	0.11	0.09	lasso	4	0.09	5.3e-07	-5.4	-5.3	1.2e-07	-0.19	0.81	0.02	FALSE
10	GTEx	Cells Transformed fibroblasts	PLA2G6	0.23	0.09	lasso	9	0.10	9.9e-08	6.4	7.0	3.2e-12	0.81	0.72	0.28	FALSE
11	GTEx	Cells Transformed fibroblasts	MAFF	0.08	0.08	lasso	3	0.06	2.2e-05	5.8	-5.1	2.8e-07	-0.73	0.32	0.30	FALSE
12	GTEx	Cells Transformed fibroblasts	TMEM184B	0.17	0.16	lasso	5	0.14	2.1e-10	4.9	-5.5	3.3e-08	-0.54	1.00	0.00	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	PLA2G6	0.28	0.24	lasso	5	0.23	1.1e-08	-5.9	6.4	1.6e-10	0.64	0.77	0.11	FALSE
14	GTEx	Esophagus Mucosa	PLA2G6	0.22	0.02	lasso	6	0.04	1.9e-03	6.4	6.9	6.4e-12	0.77	0.09	0.89	FALSE
15	GTEx	Esophagus Muscularis	PLA2G6	0.12	0.00	enet	18	0.01	1.4e-01	6.3	6.3	3.1e-10	0.62	0.09	0.27	FALSE
16	GTEx	Esophagus Muscularis	TMEM184B	0.11	0.01	enet	10	0.06	2.7e-04	3.6	-6.0	1.6e-09	-0.60	0.27	0.19	FALSE
17	GTEx	Muscle Skeletal	DMC1	0.13	0.01	enet	17	0.04	3.3e-05	6.0	6.0	2.2e-09	0.59	0.05	0.75	FALSE
18	GTEx	Nerve Tibial	PLA2G6	0.34	0.08	lasso	8	0.11	2.9e-08	-5.9	6.7	1.5e-11	0.72	0.90	0.10	FALSE
19	GTEx	Nerve Tibial	MAFF	0.14	0.06	lasso	3	0.05	1.2e-04	7.7	-7.6	2.1e-14	-0.98	0.01	0.99	FALSE
20	GTEx	Nerve Tibial	TMEM184B	0.16	0.12	lasso	7	0.14	3.6e-10	4.9	-5.3	1.3e-07	-0.47	0.99	0.00	FALSE
21	GTEx	Nerve Tibial	AL021977.1	0.16	0.05	lasso	3	0.07	9.3e-06	4.9	-6.0	2.6e-09	-0.62	0.60	0.37	FALSE
22	GTEx	Skin Sun Exposed Lower leg	ANKRD54	0.07	0.04	enet	17	0.04	1.6e-04	-5.4	-5.1	2.9e-07	-0.22	0.47	0.06	FALSE
23	GTEx	Skin Sun Exposed Lower leg	BAIAP2L2	0.09	0.09	lasso	4	0.09	5.5e-08	6.0	-6.5	1.0e-10	-0.74	0.35	0.65	FALSE
24	GTEx	Thyroid	PLA2G6	0.34	0.20	lasso	5	0.18	4.5e-14	-5.9	6.5	6.1e-11	0.67	1.00	0.00	FALSE
25	GTEx	Thyroid	TMEM184B	0.19	0.16	lasso	7	0.18	1.0e-13	5.0	-6.4	1.3e-10	-0.67	1.00	0.00	FALSE
26	GTEx	Thyroid	AL021977.1	0.20	0.11	lasso	6	0.12	2.7e-09	4.9	-6.5	6.5e-11	-0.66	0.97	0.03	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	ANKRD54	0.03	0.00	blup	397	0.01	2.2e-02	2.3	-5.5	3.5e-08	-0.28	0.19	0.06	FALSE
28	YFS	Blood	CSNK1E	0.04	0.00	enet	50	0.01	5.7e-05	0.2	-5.1	2.7e-07	-0.21	0.04	0.05	TRUE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ANKRD54	0.20	0.06	lasso	1	0.06	3.0e-07	-5.4	-5.4	8.0e-08	-0.17	0.00	1.00	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLA2G6	0.05	0.01	blup	76	0.01	7.7e-02	7.8	7.7	1.9e-14	0.83	0.01	0.86	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	BAIAP2L2	0.05	0.01	blup	52	0.03	3.7e-04	3.3	-5.4	8.1e-08	-0.43	0.08	0.23	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	PLA2G6	0.03	0.02	lasso	2	0.03	6.5e-04	6.8	6.8	1.0e-11	0.81	0.09	0.17	FALSE