TWAS hub - BID

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1090	0.0260	7.9e-07	0.055	0.057	0.119	0.099	0.105	2.5e-07	1.8e-07	3.0e-14	4.9e-12	9.4e-13
2	GTEx	Adrenal Gland	0.3954	0.0888	1.5e-04	0.020	NA	0.094	NA	0.067	6.1e-02	NA	3.0e-04	NA	2.0e-03
3	GTEx	Artery Tibial	0.1498	0.0485	1.5e-03	0.068	NA	0.067	NA	0.058	5.1e-06	NA	6.3e-06	NA	2.3e-05
4	GTEx	Brain Caudate basal ganglia	0.2850	0.1010	3.4e-03	0.159	NA	0.010	NA	0.146	2.5e-05	NA	1.6e-01	NA	5.6e-05
5	GTEx	Brain Cortex	0.2540	0.0910	7.2e-03	0.186	NA	0.020	NA	0.120	7.6e-06	NA	9.3e-02	NA	3.4e-04
6	GTEx	Brain Frontal Cortex BA9	0.3155	0.0980	2.2e-03	0.168	NA	0.199	NA	0.158	3.3e-05	NA	5.7e-06	NA	5.8e-05
7	GTEx	Brain Putamen basal ganglia	0.4850	0.1410	2.1e-03	0.171	NA	0.078	NA	0.130	7.5e-05	NA	6.7e-03	NA	5.7e-04
8	GTEx	Nerve Tibial	0.1652	0.0497	4.0e-04	0.109	NA	0.109	NA	0.106	3.8e-08	NA	4.0e-08	NA	6.1e-08
9	GTEx	Skin Sun Exposed Lower leg	0.1920	0.0460	7.2e-06	0.147	NA	0.145	NA	0.152	3.2e-12	NA	4.5e-12	NA	1.4e-12
10	GTEx	Testis	0.3320	0.0930	2.3e-05	0.125	NA	0.229	NA	0.195	3.5e-06	NA	1.6e-10	NA	4.9e-09
11	METSIM	Adipose	0.0765	0.0235	1.2e-04	0.041	0.029	0.027	0.031	0.032	7.2e-07	2.8e-05	5.3e-05	1.7e-05	1.1e-05
12	YFS	Blood	0.1710	0.0231	0.0e+00	0.214	0.188	0.213	0.213	0.213	2.7e-68	3.0e-59	5.4e-68	5.2e-68	5.6e-68
13	TCGA	Testicular Germ Cell Tumors	0.1560	0.0630	2.8e-03	-0.006	0.055	0.018	NA	0.002	5.8e-01	5.1e-03	7.7e-02	NA	2.8e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Pulse wave Arterial Stiffness index	5.9	6.9	10.4	-3.1	-1.3	-2.2	-2.8	-2.6	-3.2	-2.8	-2.9	-2.7	-2.5	-3.1	-3.1	-0.5
Pulse wave peak to peak time	5.7	6.7	9.8	3.1	1.4	2.1	2.7	2.4	3.1	2.7	2.8	2.6	2.5	3.1	3.1	0.5
Exposure to tobacco smoke outside home	5.3	7.1	14.8	-2.5	-1.8	-3.1	-3.2	-3.2	-1.9	-3.2	-2.9	-3.3	-1.9	-0.4	-0.4	-3.8
Comparative body size at age 10	4.6	12.7	17.4	-4.2	-0.6	-3.8	-3.9	-4.1	-3.9	-3.6	-4.1	-4.1	-2.7	-3.4	-2.9	-3.4
Leg fat mass (left)	4.3	16.7	32.0	-3.9	0.2	-5.6	-5.3	-5.7	-3.9	-4.4	-3.9	-5.3	-1.4	-1.1	0.1	-5.4
Leg fat mass (right)	4.1	16.0	30.7	-3.8	0.1	-5.5	-5.1	-5.5	-3.9	-4.4	-3.8	-5.2	-1.3	-1.1	0.2	-5.3
Leg fat percentage (left)	3.7	13.5	27.3	-3.5	0.0	-5.2	-4.6	-5.1	-3.5	-4.2	-3.5	-4.8	-1.1	-0.8	0.1	-4.6
Eye problems/disorders: None of the above	3.6	4.1	9.6	-2.2	-1.2	-1.8	-1.5	-1.7	-2.5	-1.2	-2.2	-1.9	-3.1	-2.0	-2.5	-1.6
Whole body fat mass	3.6	15.1	29.4	-3.6	0.2	-5.4	-4.8	-5.3	-3.6	-4.3	-3.8	-5.0	-1.4	-1.1	0.2	-5.3
Waist circumference	3.5	12.7	25.6	-3.3	0.7	-5.0	-4.8	-5.1	-3.3	-4.0	-3.1	-4.4	-0.9	-0.8	0.3	-4.7
Arm fat mass (right)	3.4	14.2	27.6	-3.6	0.4	-5.0	-4.6	-5.1	-3.5	-4.0	-3.9	-5.0	-1.3	-1.2	-0.1	-5.3
Leg fat percentage (right)	3.4	12.3	25.5	-3.3	-0.2	-5.1	-4.5	-5.0	-3.4	-4.0	-3.2	-4.5	-0.9	-0.8	0.1	-4.3
BMI	3.3	18.9	35.2	-4.6	-0.9	-4.6	-5.8	-5.9	-4.7	-4.5	-4.6	-5.4	-3.0	-2.6	-0.9	-5.0
Blood Eosinophil Count	3.2	24.5	63.0	6.2	3.9	1.7	3.0	3.1	5.8	3.1	5.4	4.7	5.2	7.6	7.9	1.2
Body fat percentage	3.2	12.5	27.4	-3.3	0.0	-5.2	-4.3	-4.8	-3.1	-4.0	-3.4	-4.7	-1.2	-0.8	0.1	-4.8
Arm fat mass (left)	3.2	13.0	25.1	-3.5	0.2	-5.0	-4.4	-4.8	-3.3	-3.8	-3.6	-4.8	-1.2	-1.2	-0.1	-5.0
Commuting to job workplace: Public transport	3.2	3.8	6.0	2.1	2.2	1.9	2.4	2.4	2.3	2.2	1.8	2.1	1.3	1.6	1.0	1.6
Trunk fat mass	3.1	13.4	27.0	-3.4	0.5	-5.2	-4.5	-4.9	-3.3	-4.2	-3.5	-4.7	-1.3	-0.9	0.1	-5.1
Pulse rate	3.1	5.3	8.3	-2.6	-2.2	-2.6	-2.8	-2.9	-2.9	-2.1	-2.1	-1.9	-2.0	-2.0	-2.3	0.4
Trunk fat percentage	2.9	11.8	26.0	-3.2	0.1	-5.1	-4.1	-4.6	-2.9	-4.0	-3.4	-4.4	-1.0	-0.8	0.1	-4.8
Body mass index (BMI)	2.9	12.5	23.6	-3.5	-0.1	-4.6	-4.5	-4.9	-3.5	-3.7	-3.5	-4.6	-1.2	-1.5	-0.2	-4.7
Weight	2.8	13.7	27.7	-3.5	1.0	-4.7	-4.8	-5.1	-3.7	-3.9	-3.4	-4.6	-1.4	-1.4	-0.0	-5.3
Hip circumference	2.8	12.2	23.2	-3.4	1.3	-4.3	-4.3	-4.8	-3.6	-3.9	-3.5	-4.3	-0.8	-1.5	-0.5	-4.8
Medication: Gliclazide	2.7	3.0	5.3	1.8	0.5	1.4	2.3	2.3	2.0	2.1	1.8	1.7	1.6	0.9	1.1	2.1
Blood White Count	2.6	19.4	73.6	5.2	3.1	0.0	1.8	2.0	5.5	2.9	3.8	2.7	2.6	7.8	8.6	-2.7
Arm fat percentage (right)	2.6	10.1	21.4	-3.0	0.5	-4.5	-3.6	-4.1	-2.7	-3.4	-3.4	-4.3	-1.2	-0.9	-0.1	-4.6
Number of full sisters	2.6	3.1	6.8	-1.9	-0.0	-1.9	-2.0	-1.9	-1.4	-1.4	-2.3	-2.6	-1.4	-0.8	-0.9	-2.6
Back pain experienced in last month	2.6	3.8	6.0	-2.4	-2.2	-2.1	-1.8	-2.0	-2.1	-2.0	-1.4	-1.7	-1.2	-2.2	-2.4	-1.4
Worry (Nagel 2018)	2.5	5.2	8.4	2.3	2.1	2.4	2.8	2.9	2.6	2.3	2.0	2.5	2.1	0.7	1.3	2.7
Arm fat percentage (left)	2.5	9.9	21.1	-3.0	0.3	-4.6	-3.6	-4.1	-2.8	-3.5	-3.2	-4.2	-1.1	-1.0	-0.2	-4.3
Illnesses of father: None of the above (group 1)	2.4	3.0	5.9	2.0	2.2	1.1	1.9	1.6	1.7	1.4	2.4	2.0	1.1	2.2	1.2	0.8
Pain experienced in last month	2.4	3.9	6.3	2.2	0.4	2.0	1.9	2.2	2.1	2.5	2.2	2.0	1.9	1.7	1.8	2.1
Other serious medical condition/disability diagnosed by doctor	2.3	3.0	4.5	1.9	0.7	1.6	1.9	2.0	1.8	2.1	1.8	1.6	2.1	1.4	1.3	1.9
Supplements: Calcium	2.3	2.5	4.5	1.6	1.5	1.2	2.0	2.1	1.7	1.8	2.0	1.5	1.5	1.2	1.0	1.1
Blood Red Count	2.2	21.5	37.5	-5.1	-1.6	-4.5	-6.1	-6.1	-5.4	-5.1	-4.9	-5.7	-3.9	-2.8	-1.4	-4.4
Qualifications: None of the above	2.2	4.8	15.0	-1.6	0.7	-3.4	-2.1	-2.9	-1.3	-2.2	-2.2	-2.6	-0.8	0.2	0.9	-3.9
Tense / ‘highly strung’	2.2	3.7	7.2	1.9	0.7	2.7	2.0	2.4	2.1	2.3	1.9	2.1	0.3	0.1	1.6	2.5
HbA1C	2.1	2.3	5.2	-1.6	-0.2	-1.8	-2.3	-1.9	-2.0	-1.5	-0.9	-1.6	-1.8	-0.8	-0.7	-1.0
Exposure to tobacco smoke at home	2.1	2.3	4.2	-1.7	-2.0	-1.7	-1.7	-1.9	-1.2	-1.2	-2.0	-1.8	-0.3	-1.0	-0.6	-1.3
Medication: Paracetamol	2.1	3.4	6.8	-1.9	-0.3	-2.3	-1.9	-2.1	-1.7	-1.7	-2.0	-2.4	-1.6	-1.0	-1.2	-2.6
Osteoporosis (self-reported)	2.0	2.5	4.7	1.8	1.4	1.3	1.7	2.1	1.7	1.8	1.4	1.5	0.6	1.4	1.2	2.2
Ever taken oral contraceptive pill	2.0	2.3	5.7	-1.6	-1.8	-0.3	-0.7	-0.8	-1.7	-0.5	-2.0	-1.5	-2.2	-1.6	-2.4	-0.4
Father’s age at death	1.9	2.5	4.8	-1.7	-0.9	-1.3	-1.7	-1.7	-1.6	-1.5	-2.2	-1.7	-1.8	-1.8	-0.7	-1.4
Leg predicted mass (left)	1.8	9.6	18.2	-3.2	0.5	-3.3	-3.9	-4.1	-3.4	-3.1	-3.2	-3.9	-1.6	-1.9	-0.7	-4.3
Length of working week for main job	1.8	2.0	4.2	-1.7	0.2	-1.0	-1.8	-2.0	-1.6	-1.5	-1.4	-1.4	-0.6	-0.8	-1.4	-1.5
Basal metabolic rate	1.8	9.9	18.7	-3.2	0.5	-3.4	-4.1	-4.3	-3.5	-3.2	-3.1	-3.9	-1.5	-1.8	-0.6	-4.3
Body Mass Index (BMI) (2010)	1.7	2.3	5.5	-1.6	-2.3	-1.3	-1.0	-1.4	-1.4	-1.2	-2.0	-2.1	-1.6	-0.9	-1.1	-1.1
Leg fat-free mass (left)	1.7	9.2	17.7	-3.1	0.5	-3.2	-3.8	-4.1	-3.4	-3.1	-3.1	-3.8	-1.6	-1.9	-0.7	-4.2
Age when periods started (menarche)	1.7	4.1	7.7	2.1	1.2	2.3	2.8	2.8	2.1	2.2	1.8	2.0	2.2	1.4	0.6	1.8
Commuting to job workplace: Car/motor vehicle	1.7	1.9	4.3	-1.3	-1.7	-1.3	-1.3	-1.4	-1.2	-1.3	-1.6	-1.8	-1.2	-0.7	0.1	-2.1
Myopia	1.7	2.4	4.1	-1.7	1.4	-0.1	-1.1	-1.5	-1.8	-2.0	-1.7	-1.8	-2.0	-1.8	-1.1	-1.0
Falls in the last year	1.6	2.2	7.0	-1.6	-2.7	-1.9	-1.0	-1.2	-0.8	-0.8	-1.7	-1.9	-0.6	-1.0	-1.2	-1.3
Arm predicted mass (right)	1.6	8.3	16.7	-3.0	0.5	-3.1	-3.9	-4.1	-3.4	-2.9	-2.7	-3.5	-1.2	-1.8	-0.5	-3.5
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.5	-1.7	-0.4	-0.2	-1.2	-1.3	-1.4	-1.0	-1.9	-1.6	-1.3	-1.4	-1.6	-1.1
Friendships satisfaction	1.6	1.9	4.4	1.8	0.4	1.0	1.5	1.5	1.8	1.4	1.1	1.4	0.9	2.1	1.6	0.9
Leg predicted mass (right)	1.6	8.4	16.0	-3.0	0.6	-2.9	-3.6	-3.8	-3.1	-2.9	-3.1	-3.6	-1.6	-1.9	-0.8	-4.0
Arm predicted mass (left)	1.6	8.3	16.5	-2.9	0.5	-3.1	-3.9	-4.1	-3.1	-2.8	-2.8	-3.6	-1.2	-1.6	-0.3	-3.9
Ulcerative Colitis	1.5	2.1	6.9	1.5	0.9	0.8	1.0	1.1	1.0	0.7	1.7	1.7	2.6	1.0	1.2	2.2
Medication: Ramipril	1.5	2.0	4.9	1.5	0.2	-0.1	1.4	1.3	2.2	1.3	1.4	0.9	2.0	1.5	2.0	0.2
Pulse wave reflection index	1.5	1.9	7.4	-1.7	-0.0	0.5	-0.8	-0.6	-1.4	-0.9	-1.7	-1.1	-1.4	-2.7	-2.0	-0.3
Medication: Ibuprofen	1.5	1.7	3.7	-1.2	-0.2	-1.5	-1.7	-1.6	-1.3	-0.9	-1.5	-1.8	-1.9	0.0	-0.4	-1.4
Illnesses of siblings: Diabetes	1.5	1.9	8.4	1.5	1.2	-0.2	0.2	-0.0	1.3	0.3	1.2	0.6	1.7	2.4	2.9	-0.6
Leg fat-free mass (right)	1.5	8.3	15.8	-3.0	0.7	-2.9	-3.6	-3.8	-3.1	-2.9	-3.1	-3.6	-1.5	-1.9	-0.8	-4.0
Qualifications: nursing, teaching	1.5	2.3	8.7	-1.2	-3.0	-0.5	-0.3	0.1	-0.9	0.2	-1.6	-1.1	-2.5	-2.1	-2.0	0.3
Ovarian Cancer	1.4	1.9	6.3	1.6	1.6	0.1	0.2	0.4	0.8	0.6	2.0	1.2	1.7	2.0	2.5	-0.3
Chronotype (morning person)	1.4	3.1	6.0	1.9	1.7	2.5	1.5	1.6	1.7	1.8	2.3	1.9	1.5	1.2	1.7	1.3
Depression (self-reported)	1.4	1.7	6.0	0.8	-0.8	1.3	1.8	1.8	1.4	2.5	1.0	1.1	0.6	-0.1	-0.3	1.4
Wheeze or whistling in the chest in last year	1.4	2.6	7.8	-1.0	-0.5	-2.8	-1.6	-1.6	-0.3	-1.6	-1.7	-2.1	-1.5	1.0	0.1	-2.5
Suffer from ‘nerves’	1.4	2.1	3.6	1.9	0.6	1.5	1.6	1.7	1.9	1.3	1.3	1.6	0.4	1.1	1.7	1.4
Overall health rating	1.4	3.0	11.5	-1.0	0.3	-2.9	-1.2	-1.9	-0.3	-2.2	-1.3	-1.8	-0.8	0.9	1.0	-3.4
Eye problems/disorders: Cataract	1.4	1.6	3.3	1.3	0.0	1.1	0.9	1.0	1.6	1.0	1.3	0.9	1.8	1.6	1.1	1.5
Arm fat-free mass (left)	1.4	7.3	15.1	-2.7	0.8	-2.8	-3.7	-3.9	-3.0	-2.6	-2.6	-3.4	-1.0	-1.3	-0.1	-3.6
Allergy or Eczema	1.3	3.5	6.3	2.1	0.2	1.4	2.1	2.1	2.5	2.1	1.5	1.5	2.2	1.8	2.0	1.7
Bilateral oophorectomy (both ovaries removed)	1.3	1.6	5.1	-1.2	-0.3	-0.8	-1.5	-1.4	-1.3	-1.3	-1.2	-1.4	-1.0	-0.5	-0.6	-2.3
Serious illness, injury or assault to yourself	1.3	1.5	3.9	1.1	1.2	0.7	1.7	1.6	1.4	1.0	1.2	1.2	2.0	-0.0	0.5	1.1
Had other major operations	1.3	1.5	5.9	-1.1	-0.2	-0.8	-1.1	-1.2	-1.2	-0.9	-1.0	-1.3	-2.4	-0.6	-0.8	-1.9
Arm fat-free mass (right)	1.3	6.8	13.9	-2.7	0.4	-2.8	-3.6	-3.7	-3.1	-2.6	-2.4	-3.3	-1.1	-1.7	-0.4	-3.1
Supplements: Vitamin C	1.3	1.5	3.8	0.9	0.3	1.5	1.4	1.4	1.2	1.7	1.2	1.3	0.9	-0.4	0.2	2.0
Whole body fat-free mass	1.3	7.6	14.0	-2.9	0.4	-2.7	-3.6	-3.7	-3.2	-2.7	-2.8	-3.4	-1.4	-1.9	-0.7	-3.7
Whole body water mass	1.3	7.2	13.6	-2.8	0.6	-2.6	-3.5	-3.7	-3.1	-2.6	-2.7	-3.3	-1.4	-1.7	-0.6	-3.6
Mother’s age at death	1.3	1.6	3.1	1.5	0.8	1.5	0.8	0.9	0.9	1.0	1.6	1.8	0.7	0.9	1.6	1.5
Number of operations (self-reported)	1.3	1.9	4.1	-1.3	-0.4	-1.4	-1.5	-1.6	-1.5	-1.9	-1.4	-1.4	-1.3	-0.9	-0.0	-2.0
Type 2 Diabetes (T2D) (2012)	1.2	1.4	4.8	-0.8	-0.2	-1.4	-2.2	-1.9	-1.4	-1.8	-0.5	-0.9	-0.3	0.1	0.2	-0.9
Number of incorrect matches in round	1.2	1.9	4.4	1.6	-0.6	1.9	1.8	1.7	1.5	2.1	1.1	1.1	-0.2	1.1	1.1	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	8.0	0.6	-1.0	2.1	1.4	1.1	0.2	1.0	1.5	1.4	-0.3	-0.8	-0.4	2.8
Neck or shoulder pain in last month	1.2	1.7	4.3	-0.7	-0.1	-1.3	-1.1	-1.1	-0.5	-1.9	-1.5	-1.6	-1.9	0.8	0.6	-2.1
Mineral and other dietary supplements	1.2	1.6	5.7	-1.5	-1.4	-0.7	-0.5	-0.4	-1.1	-0.4	-1.6	-1.1	-1.3	-2.0	-2.4	-0.1
Medication: Lisinopril	1.2	1.5	3.9	-1.3	-0.6	-1.0	-1.6	-1.7	-1.5	-2.0	-0.9	-0.6	-0.4	-1.2	-1.2	-1.0
Unable to work because of sickness or disability	1.2	1.6	5.6	-1.0	-1.0	-2.0	-1.0	-1.2	-0.1	-1.1	-1.6	-1.5	-0.7	-0.2	0.0	-2.4
Neuroticism (Nagel 2018)	1.1	2.6	4.7	1.6	1.9	1.6	1.9	2.1	1.6	1.5	1.6	1.6	1.1	0.3	0.8	2.2
Past tobacco smoking	1.1	2.0	4.8	1.1	-0.1	1.1	1.4	2.0	1.1	1.7	1.4	1.8	1.8	-0.3	-0.3	2.2
Hearing difficulty/problems with background noise	1.1	1.7	3.2	1.6	0.3	1.0	1.4	1.4	1.8	1.3	1.4	1.1	1.1	1.6	1.8	0.3
Pain all over the body in last month	1.1	1.1	2.3	-0.9	-0.5	-1.5	-1.3	-1.2	-1.3	-1.1	-0.7	-1.1	-1.0	-0.2	-0.6	-1.5
Emphysema/chronic bronchitis	1.1	1.2	4.3	-1.3	0.8	-0.9	-0.4	-0.6	-1.0	-0.8	-1.7	-1.2	-0.8	-1.2	-2.1	-0.2
Medication for pain relief, constipation, heartburn	1.1	1.9	5.6	0.9	0.8	2.2	1.2	1.3	0.4	1.3	1.7	1.6	1.1	-0.1	-0.6	2.4
Migraine (self-reported)	1.1	1.4	4.7	1.3	1.6	0.2	0.0	0.0	0.8	0.5	1.4	0.9	0.7	2.1	2.2	-0.8
Financial situation satisfaction	1.1	1.3	5.0	-0.7	-0.2	-1.8	-1.0	-1.5	-0.8	-1.2	-0.9	-1.1	-0.2	0.8	0.5	-2.2
Supplements: Fish oil (including cod liver oil)	1.1	1.5	7.4	1.3	1.0	-0.5	-0.3	-0.3	0.7	-0.4	1.5	0.8	1.4	1.9	2.7	-0.2
Diastolic blood pressure, automated reading	1.1	3.6	7.1	-2.3	-0.7	-2.3	-2.5	-2.7	-2.2	-2.2	-1.7	-2.0	-0.2	-1.5	-1.7	-0.6
Alzheimer’s Disease (in father)	1.0	1.1	5.3	-0.6	-0.4	-1.2	-0.7	-1.1	-0.3	-0.4	-1.1	-1.5	-1.0	0.8	0.5	-2.3
LDL Cholesterol	1.0	1.5	4.8	1.2	1.1	0.5	1.0	1.1	0.8	1.1	2.2	1.6	1.7	0.7	0.6	1.2
Smoking Status	1.0	2.5	6.8	-0.9	-0.0	-1.3	-1.9	-2.1	-1.1	-1.9	-1.6	-1.9	-1.7	0.5	1.1	-2.6
Type 2 Diabetes (T2D) (2018)	1.0	1.8	5.3	-1.3	0.9	-2.3	-1.8	-1.6	-1.6	-1.1	-1.2	-1.5	-0.9	-0.6	-0.4	-1.4
Ever had hysterectomy (womb removed)	1.0	1.1	9.0	-0.3	0.6	-1.4	-0.6	-0.8	-0.0	-1.1	-0.5	-0.8	-0.2	0.6	0.4	-3.0
Multivitamins +/- minerals	1.0	1.2	2.5	1.3	0.8	1.4	1.0	1.0	0.9	0.8	1.5	1.3	0.4	0.9	0.8	1.6
Medication: Simvastatin	1.0	1.5	6.2	-1.0	-0.1	-2.5	-1.6	-1.5	-1.0	-1.9	-0.9	-1.1	-0.1	-0.3	-0.2	-0.9
Medication: Ventolin 100micrograms inhaler	1.0	1.3	5.7	-1.2	-0.0	-0.5	-0.6	-0.7	-1.1	-0.6	-1.4	-0.9	-1.6	-1.0	-2.4	0.4
Knee pain experienced in last month	1.0	1.5	4.4	-0.9	0.7	-1.8	-1.3	-1.2	-0.7	-2.1	-1.4	-1.2	-0.3	-0.1	0.1	-2.0
Illnesses of father: Heart disease	1.0	1.4	2.5	-1.4	-1.1	-0.6	-1.2	-1.0	-1.3	-1.2	-1.6	-1.3	-0.1	-1.5	-1.2	-0.7
Smoking status: Previous	1.0	1.5	3.3	-1.4	-0.2	-0.2	-1.2	-1.5	-1.3	-1.2	-1.3	-1.6	-1.6	-0.6	-1.0	-1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	10.6	0.5	-1.6	2.3	1.4	1.3	0.5	1.0	0.8	1.4	0.5	-1.0	-0.7	3.3
Medication: Paracetamol	1.0	1.6	5.2	-1.1	-0.4	-1.9	-1.1	-1.4	-0.8	-1.0	-1.4	-1.7	-0.7	-0.3	-0.3	-2.3
Triglycerides	0.9	1.5	5.0	-1.3	0.2	-2.2	-0.6	-0.8	-0.8	-0.9	-1.4	-1.6	-0.1	-1.0	-1.1	-2.0
Townsend deprivation index at recruitment	0.9	1.3	5.7	0.0	0.6	-1.0	-0.5	-1.1	0.6	-0.7	-0.6	-1.0	-0.5	1.4	2.0	-2.4
Hayfever, allergic rhinitis or eczema	0.9	1.9	4.4	1.5	0.3	1.5	1.3	1.4	1.5	1.4	1.2	1.6	1.1	0.9	1.2	2.1
Trunk fat-free mass	0.9	5.3	10.3	-2.4	0.5	-2.1	-3.1	-3.2	-2.8	-2.2	-2.2	-2.8	-1.3	-1.5	-0.5	-3.1
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	3.5	-0.9	0.4	-1.1	-1.4	-1.3	-1.1	-0.6	-1.0	-1.4	-1.9	0.1	-0.2	-1.2
Trunk predicted mass	0.9	5.3	10.4	-2.4	0.5	-2.1	-3.1	-3.2	-2.8	-2.2	-2.2	-2.8	-1.3	-1.4	-0.4	-3.1
Number of full brothers	0.9	1.2	3.7	1.0	1.8	-0.1	0.2	-0.1	0.8	-0.1	1.2	0.6	1.1	1.9	1.8	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.8	0.3	-0.8	1.8	0.9	0.9	-0.3	1.4	1.2	0.9	-0.2	-1.3	-0.5	1.9
Alcohol intake frequency.	0.9	2.1	5.5	-1.5	-1.2	-2.3	-1.2	-1.3	-0.9	-1.1	-2.0	-1.9	-0.8	-0.9	-0.5	-2.0
Long-standing illness, disability or infirmity	0.9	1.4	3.0	1.3	-0.4	0.2	1.5	1.2	1.7	1.3	1.1	0.9	1.3	1.4	1.2	0.4
Alcohol drinker status: Previous	0.9	1.0	2.2	-1.2	0.2	-1.1	-0.7	-0.7	-0.6	-0.6	-1.3	-1.5	-1.0	-1.1	-1.0	-1.2
Major Depression (MDD)	0.8	1.0	3.9	-1.1	-2.0	-1.1	-0.6	-0.5	-0.6	0.1	-0.6	-0.7	-1.1	-1.4	-1.4	0.0
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.6	1.1	0.2	1.3	0.7	0.8	0.8	0.2	1.1	1.2	1.0	1.6	0.3	0.6
Worrier / anxious feelings	0.8	1.5	3.2	1.3	0.2	0.9	1.8	1.7	1.7	1.6	0.7	1.1	1.3	0.5	0.8	1.1
Qualifications: College or University degree	0.8	2.5	8.4	0.4	-2.6	2.2	1.4	1.8	0.3	1.4	0.5	1.0	-1.0	-0.8	-1.5	2.9
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.2	-1.0	1.2	-1.0	-1.3	-1.0	-0.5	-0.6	-1.1	-1.5	-1.2	-0.5	-0.2	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.9	-0.2	0.1	-1.6	-1.0	-1.3	-0.4	-0.9	-0.0	-0.7	-1.0	1.0	1.0	-1.7
Eye problems/disorders: Glaucoma	0.8	1.0	6.0	0.5	2.4	-0.3	-0.3	-0.4	0.4	-0.2	0.9	0.4	1.5	0.7	1.5	0.2
Average weekly beer plus cider intake	0.8	1.1	2.6	-0.7	0.7	-1.0	-1.3	-1.5	-0.8	-1.5	-1.1	-1.2	-0.0	0.1	0.8	-1.6
Crohns Disease (2017)	0.7	1.5	4.8	-1.4	-2.2	-0.4	-0.9	-0.5	-1.1	-0.4	-0.8	-0.8	-1.4	-1.7	-1.9	-0.6
Ulcerative Colitis (UC)	0.7	1.2	3.6	1.4	-0.0	0.5	0.4	0.5	1.0	0.1	1.7	1.5	0.1	1.4	1.9	1.3
Angina	0.7	0.9	1.7	-1.2	-0.9	-1.1	-0.3	-0.7	-0.6	-1.0	-1.2	-1.2	-0.6	-1.3	-1.1	-0.8
Relative age voice broke	0.7	1.1	3.5	0.9	-0.1	0.4	1.8	1.5	1.2	1.9	0.8	0.8	0.3	0.2	0.4	1.0
Supplements: Glucosamine	0.7	0.9	3.4	1.1	1.8	0.7	0.3	0.4	0.5	0.0	0.7	0.5	0.7	1.5	1.5	0.2
Financial difficulties in last 2 years	0.7	0.9	1.7	1.1	0.5	0.5	1.3	0.7	1.1	0.6	0.8	1.0	0.9	1.0	1.1	1.2
Illnesses of siblings	0.7	1.0	3.8	-0.8	-0.3	0.2	0.0	0.2	-1.2	0.2	-0.8	-0.5	-1.9	-1.1	-1.9	1.1
Impedance of arm (right)	0.7	3.2	5.9	2.1	0.7	1.4	2.4	2.4	2.4	1.1	1.7	2.3	1.0	2.1	0.8	1.4
Loud music exposure frequency	0.7	0.8	1.5	-0.5	-0.4	-0.9	-1.2	-1.2	-0.5	-0.7	-1.2	-1.1	-1.0	0.4	0.8	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	4.0	0.3	-0.3	0.5	0.8	1.0	0.4	1.2	0.6	0.7	0.5	-1.0	-0.6	2.0
Pulse rate, automated reading	0.7	2.4	6.3	-0.9	-0.8	-2.5	-2.2	-2.2	-0.9	-2.0	-1.4	-1.4	-1.3	0.6	0.7	-1.4
Medication: Aspirin	0.7	0.9	2.2	0.6	0.1	0.4	1.5	1.4	1.1	1.1	0.6	0.7	1.4	-0.9	0.7	0.7
Heart disease (siblings)	0.7	0.9	1.7	1.1	1.1	-0.1	0.7	0.7	1.3	0.4	1.3	1.0	0.7	1.3	1.1	-0.5
Lupus	0.6	1.0	5.2	0.2	0.6	0.9	1.1	0.8	0.1	1.1	0.9	0.6	-1.1	-0.8	-0.7	2.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.3	1.0	0.8	0.9	0.6	0.7	0.6	0.5	0.9	0.8	1.1	0.4	1.5	-0.1
Medication: Co-codamol	0.6	0.7	1.6	0.8	-0.6	0.7	1.3	1.0	1.3	0.9	0.2	0.5	0.4	1.1	0.9	-0.2
Current tobacco smoking	0.6	1.0	2.8	-0.1	0.4	-0.9	-1.0	-0.9	-0.5	-1.0	-1.0	-1.1	-1.7	0.7	1.3	-1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.5	-0.9	0.1	-0.7	-0.6	-1.1	-1.2	-1.2	-0.8	-0.6	-0.4	-0.3	-0.7	-1.2
Happiness	0.6	0.7	2.9	0.8	1.5	-0.1	0.3	-0.1	0.5	0.1	0.8	0.5	0.8	1.7	1.1	-0.3
Breastfed as a baby	0.6	0.8	4.0	0.5	-0.9	1.4	0.2	0.5	-0.2	0.7	0.8	0.9	0.6	-0.2	0.1	2.0
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.1	0.5	1.2	1.4	1.0	1.3	0.5	1.2	0.2	0.5	-1.4	-0.3	-0.5	1.4
Glaucoma (self-reported)	0.6	0.7	4.5	0.2	2.1	-0.3	-0.4	-0.6	0.3	-0.5	0.2	-0.1	1.0	0.4	1.4	-0.5
Angina (self-reported)	0.6	0.7	1.7	-1.0	-1.0	-0.9	0.0	-0.4	-0.5	-0.7	-1.1	-1.0	-0.6	-1.3	-1.2	-0.6
Medication: Omeprazole	0.6	0.7	1.5	1.0	-0.6	0.9	0.9	1.1	1.2	0.3	0.4	1.0	0.1	1.0	1.0	0.1
Age at last live birth	0.6	0.9	6.0	-0.7	-2.5	0.7	0.3	0.1	-0.9	0.1	-0.5	-0.6	-0.4	-1.2	-1.3	0.5
Asthma (self-reported)	0.6	1.2	4.4	-0.7	-0.3	-2.1	-0.6	-0.7	-0.3	-0.8	-1.5	-1.3	-1.8	-0.2	-0.1	-1.1
Osteoarthritis (self-reported)	0.6	0.8	2.2	1.0	0.8	0.7	0.9	0.7	0.8	-0.2	0.9	0.7	1.3	1.5	1.3	-0.5
Medication: Bendroflumethiazide	0.6	0.9	2.7	-0.3	0.8	-1.1	-1.3	-1.3	-0.7	-1.6	0.3	-0.3	1.0	-0.5	1.2	-0.9
Ever smoked	0.6	1.1	3.6	-0.4	0.6	-0.4	-0.9	-1.3	-0.7	-1.1	-0.9	-1.2	-1.5	0.7	1.0	-1.9
Pack years of smoking	0.6	0.9	2.3	-1.0	-0.4	-1.0	-1.3	-1.2	-0.9	-0.9	-0.8	-1.3	-0.3	-0.7	-0.0	-1.5
Lung FVC	0.5	2.4	11.4	-0.2	-0.5	2.0	1.0	1.1	-0.3	0.6	0.2	0.9	1.4	-2.6	-1.8	3.4
Hand grip strength (left)	0.5	1.2	3.4	-1.2	-0.4	0.2	-1.5	-1.4	-1.9	-0.9	-1.1	-1.2	-1.0	-1.2	-0.7	-0.1
Vitamin and mineral supplements	0.5	0.6	1.0	-0.8	-0.9	-1.0	-0.8	-0.6	-0.8	-0.9	-0.9	-0.8	-0.1	-0.4	-0.8	-1.0
Pack years adult smoking proportion	0.5	0.7	1.4	-0.9	-0.0	-0.6	-1.1	-1.0	-1.0	-0.7	-0.7	-1.1	-0.4	-0.8	-0.1	-1.2
Average weekly fortified wine intake	0.5	0.6	4.6	-0.4	-2.1	-0.3	-0.5	-0.3	-0.3	-0.6	-0.6	-0.3	-1.1	-0.3	-0.2	-0.7
Medication: Atenolol	0.5	0.6	2.8	-0.3	0.1	0.2	0.5	0.4	-0.1	0.1	0.3	0.6	1.5	-1.7	-0.6	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.0	0.7	1.7	1.0	1.1	1.1	0.9	1.0	-0.1	0.4	-1.4	0.1	0.2	0.5
Alcohol intake versus 10 years previously	0.5	0.7	4.1	0.0	-0.3	-1.4	-0.5	-0.5	0.3	-0.4	-0.1	-0.3	-0.4	0.6	1.1	-2.0
Asthma	0.5	1.1	4.3	-0.6	-0.3	-2.1	-0.5	-0.6	-0.2	-0.8	-1.4	-1.2	-1.9	-0.1	-0.1	-0.9
Medication: Lansoprazole	0.5	0.5	2.4	-0.0	-0.7	-1.5	0.1	-0.2	0.8	-0.1	-0.3	-0.5	-0.3	0.7	0.7	-1.4
Impedance of arm (left)	0.5	2.3	4.8	1.7	0.3	1.0	2.2	2.1	1.9	0.8	1.6	2.0	0.6	1.6	0.3	1.5
Peak expiratory flow (PEF)	0.5	1.2	2.3	-1.1	-0.1	0.3	-1.5	-1.5	-1.4	-1.4	-1.1	-1.3	-0.8	-1.2	-0.2	-0.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	-0.6	-0.1	-0.1	-0.9	-1.2	-0.7	-1.2	-0.2	-0.4	-1.3	-0.6	0.2	-1.0
Headache pain in last month	0.5	0.9	2.9	-0.9	0.0	-1.7	-0.8	-1.1	-0.5	-0.7	-1.0	-0.9	-1.6	-0.1	-0.6	-0.8
Birth weight	0.5	1.1	3.5	-0.9	1.9	-0.3	-0.9	-1.1	-1.3	-1.1	-1.2	-1.0	-0.1	-1.1	-0.2	-1.0
Chronic bronchitis/emphysema (mother)	0.5	0.5	2.2	0.5	0.6	-0.7	-0.2	-0.0	1.0	-0.2	-0.4	-0.1	-0.4	1.4	1.5	-0.7
High blood pressure (siblings)	0.5	0.8	1.7	-0.4	-0.6	-0.8	-1.1	-1.2	-0.1	-1.3	-0.7	-0.6	1.1	-0.3	1.0	-1.3
Number of children fathered	0.5	0.6	2.2	-0.8	-0.3	0.2	-0.2	0.0	-1.2	-0.2	-0.7	-0.7	-0.6	-1.5	-1.4	0.3
Medication: Allopurinol	0.5	0.7	3.9	-0.6	-2.0	-0.1	0.1	0.1	-0.5	0.4	-0.5	-0.3	0.4	-1.0	-1.7	0.0
Medication: Seretide 50 evohaler	0.5	0.6	2.1	-0.5	-0.7	0.2	0.3	0.4	-0.1	0.3	-1.1	-0.6	-1.3	-0.7	-1.5	0.7
Family relationship satisfaction	0.5	0.6	4.3	0.6	2.1	0.1	0.4	0.5	0.3	0.4	0.9	1.0	0.5	0.5	0.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.1	0.7	0.3	0.3	0.3	0.5	1.0	-0.5	-0.3	-0.0	-0.2	1.8	1.3	-0.8
Loneliness, isolation	0.5	0.7	2.9	0.7	1.7	0.8	1.0	0.8	0.9	0.9	0.9	0.7	-0.3	0.2	0.1	0.3
Commuting to job workplace: Walk	0.5	0.6	2.3	0.7	-0.0	0.3	0.9	0.8	0.9	1.5	0.5	0.4	0.5	1.2	0.1	0.7
Breast cancer (self-reported)	0.5	0.6	1.2	-0.7	-1.1	-1.0	-0.9	-0.9	-0.5	-0.9	-0.8	-1.0	-0.2	-0.1	0.4	-0.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.6	0.2	0.4	-1.3	-0.1	-0.1	0.6	-0.8	-0.8	-0.7	-0.6	1.2	1.0	-0.9
Pain type(s) experienced in last month: Hip pain	0.5	0.7	2.3	0.5	1.5	-0.6	0.6	0.3	1.4	0.2	0.2	-0.2	0.6	1.1	0.8	-1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.7	0.4	1.2	1.3	1.0	0.8	0.3	0.5	0.4	0.7	-0.4	-0.1	-0.6	0.9
Age started oral contraceptive pill	0.5	0.6	2.3	0.8	0.7	0.4	0.3	0.5	0.5	0.6	0.6	0.2	0.8	0.9	1.5	1.1
Impedance of whole body	0.5	2.5	4.2	1.8	0.3	1.0	2.0	1.9	2.0	0.8	1.8	2.0	1.0	2.0	0.7	1.8
Reaction Time	0.4	0.7	1.8	0.6	-1.1	0.2	1.2	1.3	1.0	1.1	0.6	0.7	-0.3	0.3	-0.3	1.0
Breast Cancer	0.4	1.0	3.1	0.7	1.6	-1.1	-0.0	-0.1	1.0	-0.2	0.3	-0.0	0.5	1.3	1.8	-1.6
Crohns Disease (2012)	0.4	0.6	2.7	-0.9	-1.0	-0.3	-0.6	-0.3	-1.0	-0.0	-0.2	-0.2	0.5	-1.3	-1.6	0.3
Mean Putamen Volume	0.4	0.4	1.4	0.7	0.7	-0.4	0.1	0.2	0.6	-0.3	0.3	0.5	0.9	1.0	1.2	0.6
Primary Biliary Cirrhosis	0.4	0.6	2.7	-0.3	-0.5	-1.6	-1.4	-1.0	-0.9	-0.7	0.1	0.1	-0.7	-0.1	0.1	0.3
Rheumatoid Arthritis	0.4	0.6	1.4	-0.9	0.8	-0.5	-0.4	-0.6	-0.7	-0.3	-1.1	-1.2	-0.7	-0.3	-0.7	-1.1
Schizophrenia (2014)	0.4	0.9	3.8	1.0	0.0	0.9	1.0	1.2	0.9	0.7	0.8	1.3	0.4	0.4	0.4	1.9
Average weekly spirits intake	0.4	0.5	1.2	-0.5	0.5	-0.8	-0.9	-0.6	-0.3	-0.6	-0.6	-0.5	1.1	0.0	-0.9	-1.0
Hearing difficulty/problems: Yes	0.4	0.6	1.8	0.7	-0.9	-0.4	0.8	0.8	1.3	0.7	0.0	0.1	0.1	1.0	1.0	-0.5
Supplements: Zinc	0.4	0.4	1.2	-0.1	0.8	1.1	0.4	0.3	0.2	0.8	-0.0	0.3	0.8	-0.9	-0.4	1.0
Medication: Metformin	0.4	0.6	2.5	0.8	0.9	-0.8	0.3	0.4	0.8	-0.0	0.6	0.4	1.1	0.9	1.6	0.1
Severe depression (siblings)	0.4	0.5	1.6	0.1	-1.0	-0.3	1.0	0.6	0.6	0.8	0.2	0.1	-0.8	0.3	-0.4	-1.3
Fed-up feelings	0.4	0.6	3.7	-0.4	1.4	-0.8	-0.1	-0.4	-0.1	-0.2	-0.4	-0.8	-1.9	-0.4	0.2	-0.8
Stomach or abdominal pain in last month	0.4	0.4	1.3	-0.9	0.2	-0.2	-0.7	-0.9	-1.1	-0.8	-0.3	-0.4	-0.1	-1.0	-0.7	0.2
Chronic bronchitis/emphysema (father)	0.4	0.5	2.5	-0.4	1.2	-0.6	-0.3	-0.3	-0.2	-0.5	-0.5	-0.8	-1.6	0.3	-0.0	-0.8
Nervous feelings	0.4	0.8	2.0	0.8	-0.0	0.9	1.4	1.4	1.2	1.1	0.5	0.8	-0.0	-0.2	0.4	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.6	-1.0	-1.5	-1.4	-0.9	-0.9	-0.5	-0.7	-1.1	-1.3	-0.4	-0.4	-0.0	-1.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	2.4	0.5	0.4	-0.1	-0.1	-0.3	0.2	-0.4	0.5	0.0	0.3	1.6	1.4	0.4
Diabetes (self-reported)	0.4	0.6	2.1	0.3	1.3	-1.5	-0.5	-0.4	0.1	-0.3	0.1	-0.3	0.7	1.0	1.1	-1.0
Time employed in main current job	0.4	0.4	2.2	-0.0	1.5	-0.7	-0.6	-0.5	-0.1	-0.7	0.4	0.1	-0.5	0.3	0.6	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.8	-0.2	-0.3	-1.0	-0.4	-0.8	0.1	-1.0	-0.5	-0.8	-1.0	0.6	0.9	-1.3
Forced vital capacity (FVC), Best measure	0.4	1.4	5.9	0.6	0.6	2.4	1.2	1.3	0.5	1.0	0.8	1.3	0.5	-0.8	-0.5	1.9
Mean time to correctly identify matches	0.4	0.7	1.9	0.7	-1.4	-0.4	1.1	1.3	1.3	1.0	0.6	0.6	-0.2	0.3	0.2	0.4
Comparative height size at age 10	0.4	2.2	4.5	-1.1	0.8	-1.7	-2.0	-1.9	-1.7	-2.1	-0.8	-1.1	-1.6	-0.5	0.3	-2.1
Had major operations	0.4	0.5	1.9	-0.6	0.7	-1.0	-0.2	-0.5	-0.5	-1.4	-1.0	-0.4	-0.6	-0.6	-0.6	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.2	0.0	0.8	-0.0	-0.9	-0.9	-0.2	-1.1	0.2	-0.2	0.3	1.5	0.4	-0.8
Medication: Aspirin	0.4	0.5	1.4	0.3	-0.3	0.3	1.2	1.1	0.9	1.0	-0.0	0.2	0.8	-1.0	0.5	0.5
Smoking status: Current	0.4	0.7	2.8	0.3	0.2	-0.7	-0.7	-0.6	-0.1	-0.8	-0.6	-0.6	-1.3	1.1	1.7	-0.6
Number of self-reported non-cancer illnesses	0.4	0.6	2.6	-0.6	-1.6	-1.3	-0.3	-0.6	-0.0	-0.9	-0.6	-0.8	0.7	-0.1	-0.2	-1.0
Guilty feelings	0.4	0.6	1.5	0.8	0.1	0.4	0.3	0.7	0.9	1.0	0.8	0.2	-0.8	1.2	0.9	0.5
Hearing aid user	0.4	0.5	2.3	-0.6	-1.2	-1.5	0.0	-0.2	-0.5	0.1	-0.5	-0.4	-0.5	-0.3	-0.9	-0.7
Risk taking	0.4	0.6	1.4	-0.9	-0.7	1.1	-0.2	-0.5	-0.6	0.1	-1.2	-1.1	-0.1	-1.1	-0.9	-0.0
Fractured/broken bones in last 5 years	0.4	0.5	1.4	0.7	0.6	0.1	1.0	1.0	1.0	1.2	0.6	0.2	-0.7	0.5	0.5	-0.2
Age at First Birth	0.3	0.5	1.2	0.6	-0.8	0.8	0.8	0.9	1.0	1.1	0.4	0.3	-0.1	0.8	0.1	0.4
Coronary Artery Disease (CAD)	0.3	0.4	1.3	-0.1	0.4	-0.2	-0.9	-0.6	-0.5	-0.7	0.4	0.0	0.8	-0.1	1.1	0.7
HDL Cholesterol	0.3	0.4	1.0	0.7	-0.7	0.9	0.1	0.2	0.6	0.4	0.5	0.3	-0.7	0.9	1.0	0.8
Heel T-Score	0.3	2.3	5.1	-1.8	-2.3	0.7	-1.3	-1.3	-1.8	-0.8	-1.6	-1.6	-1.8	-1.9	-1.5	-0.6
Neuroticism	0.3	0.6	1.5	0.6	1.2	0.6	1.1	1.1	1.1	0.9	0.4	0.3	-0.5	0.3	0.0	0.8
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.8	-0.5	-1.3	0.1	-0.3	-0.2	-0.6	-0.1	-0.7	-0.5	-1.0	-0.9	-0.3	-0.5
Systolic blood pressure, automated reading	0.3	0.8	3.3	-0.8	-0.8	-1.8	-1.0	-1.1	-0.5	-0.7	-0.6	-1.1	0.7	-0.4	-0.3	-1.1
Medication for hormone replacement therapy	0.3	0.3	1.5	0.5	0.5	0.3	0.1	0.0	0.3	0.3	0.1	0.1	-0.7	0.6	1.2	-0.9
Diabetes (mother)	0.3	0.4	1.7	-0.3	-0.4	-0.6	-1.3	-1.1	-0.6	-0.5	0.4	0.1	0.1	0.1	0.1	-0.8
Maternal smoking around birth	0.3	0.5	2.2	-0.4	1.5	-0.7	-0.5	-0.7	-0.6	-0.7	-0.3	-0.4	1.1	-0.3	0.2	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.8	-0.3	0.9	-0.0	0.0	-0.2	0.1	0.1	-0.7	-0.9	-1.3	0.2	0.1	-0.7
Taking other prescription medications	0.3	0.4	1.2	0.5	-0.5	-0.0	1.1	0.9	1.0	0.5	-0.2	0.1	1.0	0.3	0.5	0.2
Qualifications: CSEs or equivalent	0.3	0.4	1.6	0.4	1.3	0.5	-0.2	-0.3	0.0	-0.2	0.6	0.3	1.2	1.0	0.8	-0.2
High blood pressure (mother)	0.3	0.4	1.2	0.5	1.1	0.1	0.5	0.4	0.7	0.2	0.1	0.7	1.0	0.0	0.9	-0.4
Alcohol usually taken with meals	0.3	0.5	1.8	0.6	-0.1	1.3	0.7	0.9	0.4	0.8	0.9	0.5	-0.6	0.4	-0.4	0.9
Hair/balding pattern: Pattern 2	0.3	0.3	0.9	-0.6	0.6	-0.5	-0.4	-0.3	-0.5	-0.5	-0.5	-0.6	0.8	-1.0	-0.5	-0.4
Had menopause	0.3	0.4	1.1	-0.2	-0.3	-1.1	-1.1	-0.7	-0.6	-0.9	-0.1	-0.6	0.7	0.4	0.6	0.2
Forced vital capacity (FVC)	0.3	1.2	6.2	0.5	0.1	2.5	0.8	0.9	0.4	0.6	0.6	1.3	0.8	-1.0	-0.1	1.7
Mouth/teeth dental problems	0.3	0.4	1.3	-0.7	-0.8	0.2	-0.6	-0.6	-0.7	-0.0	-0.5	-0.3	-1.1	-0.5	-0.9	0.7
Qualifications: A levels/AS levels or equivalent	0.3	0.7	3.1	-0.2	-1.0	0.7	0.2	0.6	0.2	0.6	-1.0	-0.4	-1.8	-0.7	-0.6	1.4
Mouth/teeth dental problems: Dentures	0.3	0.4	2.5	0.3	-0.2	-0.1	0.5	-0.0	0.1	-0.5	-0.2	-0.3	1.6	0.8	0.6	-1.2
Illnesses of mother	0.3	0.4	2.3	-0.3	-1.1	0.5	0.4	0.3	-0.0	0.3	0.1	-0.0	-0.7	-0.3	-1.5	0.2
Birth weight of first child	0.3	0.6	2.8	-0.4	-0.1	-0.4	-0.2	-0.2	-0.0	-0.3	-1.0	-0.9	-1.6	0.1	-0.1	-1.7
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	1.8	-0.0	1.3	0.9	-1.0	-0.4	-0.6	-0.1	0.1	-0.0	-1.2	0.4	0.2	-0.1
Worry too long after embarrassment	0.3	0.4	2.3	0.8	0.3	-0.2	0.3	0.2	0.9	0.2	0.3	0.3	0.1	0.9	1.5	0.6
Age at first live birth	0.3	0.5	2.9	-0.4	-1.7	0.6	0.7	0.5	-0.2	0.3	-0.4	-0.4	-0.2	-0.9	-0.8	0.5
Health satisfaction	0.3	0.4	1.1	-0.5	0.1	-0.8	-0.6	-1.0	-0.5	-0.9	-0.4	-0.6	0.6	-0.1	-0.0	-1.1
Shortness of breath walking on level ground	0.3	0.3	1.8	0.4	1.3	0.3	0.2	0.1	0.4	0.3	-0.1	-0.3	0.6	0.9	0.8	-0.5
Medication: Blood pressure	0.3	0.5	2.1	0.0	-1.0	-1.4	0.8	0.4	0.8	-0.2	-0.3	-0.2	1.4	-0.1	0.1	-0.6
Leg pain on walking	0.3	0.4	2.2	0.1	1.5	-0.9	0.0	-0.3	-0.0	-0.9	-0.2	-0.3	0.2	0.6	0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.8	0.5	-0.5	0.3	0.3	0.9	0.9	0.8	0.3	0.7	0.8	0.3	-0.2	0.5
Average weekly champagne plus white wine intake	0.3	0.4	2.2	0.3	1.1	0.6	0.2	0.1	0.1	0.3	0.2	0.2	-1.2	0.2	0.5	1.5
Miserableness	0.3	0.5	3.8	-0.2	1.5	-0.5	-0.0	0.1	-0.1	0.2	-0.0	-0.3	-1.9	-0.4	-0.2	-0.4
Wears glasses or contact lenses	0.3	0.3	2.0	0.1	-0.3	0.5	0.4	0.4	-0.4	0.4	0.6	0.7	-0.0	-0.5	-0.7	1.4
Medication: Atorvastatin	0.3	0.4	2.2	0.1	-0.8	0.2	1.0	0.4	0.8	-0.1	0.0	0.0	1.5	-0.4	0.1	-0.2
Illnesses of father: High blood pressure	0.3	0.3	2.1	-0.3	-1.4	-0.5	-0.3	-0.2	0.1	-0.3	-0.4	-0.2	-0.4	-0.8	0.1	-0.8
Ever depressed for a whole week	0.3	0.4	1.6	-0.4	-1.0	-1.3	-0.6	-0.8	-0.4	-0.3	-0.4	-0.5	-0.6	0.8	0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.1	0.9	1.1	1.4	0.6	0.9	0.2	1.3	0.6	0.9	-0.3	1.2	-0.2	1.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	3.0	0.2	-1.7	-0.1	0.2	0.3	0.6	-0.1	-0.5	0.1	-0.9	0.4	0.3	-0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.2	-0.7	0.3	-0.8	-0.2	-0.5	-0.6	-0.3	-0.4	-0.6	0.3	-1.1	-0.6	-0.4
Bipolar Disorder (2018)	0.2	0.3	0.9	0.5	0.4	0.8	0.2	1.0	0.2	0.6	0.6	0.6	0.7	-0.1	0.2	0.9
Depressed Affect (Nagel 2018)	0.2	0.5	2.4	0.3	1.6	0.4	0.8	0.8	0.2	0.7	0.5	0.5	0.0	-0.7	-0.3	1.1
Depression (Nagel 2018)	0.2	0.3	1.6	-0.5	0.3	-0.2	0.1	0.2	-0.4	0.1	-0.6	-0.5	-0.7	-1.3	-0.8	0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	0.8	0.5	-0.9	-0.5	0.7	-0.1	0.6	-0.2	0.3	0.5	0.0	0.7	0.5	0.6
Neuroticism (2016)	0.2	0.3	1.5	0.0	-0.3	-0.4	0.1	0.2	0.7	-0.4	-0.2	-0.4	-1.2	-0.0	0.6	-0.6
Waist Hip Ratio (WHR)	0.2	0.8	3.6	0.7	-0.4	-0.7	-0.1	-0.2	1.1	-0.0	0.9	0.0	0.4	1.8	1.9	-0.3
Lung FEV1/FVC ratio	0.2	1.1	4.6	-0.7	1.0	-0.5	-1.6	-1.6	-1.4	-2.1	-0.4	-0.1	0.6	-0.1	-0.6	0.5
Tanning	0.2	2.3	4.4	1.6	1.7	1.9	2.1	1.7	1.5	1.0	1.8	1.9	1.0	1.3	0.7	0.8
Number of treatments/medications taken	0.2	0.4	2.3	-0.0	-0.6	-1.5	0.2	-0.1	0.4	-0.7	-0.3	-0.6	0.2	-0.2	1.0	-0.8
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	-0.6	0.3	-0.0	0.1	-0.0	-0.4	0.1	-0.5	-0.5	-1.0	-1.1	-0.9	-0.1
Impedance of leg (right)	0.2	1.2	3.3	1.1	-0.5	0.7	0.9	0.8	0.9	0.4	1.6	1.6	0.9	1.3	0.5	1.8
Hand grip strength (right)	0.2	0.5	1.0	-0.7	-0.1	0.1	-0.9	-0.8	-1.0	-0.5	-0.7	-1.0	-0.8	-0.6	0.0	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.5	-0.5	-0.8	-0.9	-0.7	-0.5	-0.2	-0.1	-0.9	-1.1	-0.9	-0.2	0.5	-1.2
High blood pressure	0.2	0.5	1.6	-0.5	-0.3	-1.3	-0.4	-0.6	0.2	-1.1	-0.3	-0.6	0.2	-0.9	0.4	-1.0
Impedance of leg (left)	0.2	1.1	2.5	1.2	-0.0	0.5	1.0	0.9	1.2	0.4	1.3	1.4	0.9	1.6	0.7	1.6
Heart attack	0.2	0.2	1.0	-0.6	0.1	-0.8	-0.0	-0.3	-0.5	-0.1	-0.3	-0.6	0.1	-1.0	-0.5	-0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.1	0.5	-0.5	0.1	0.3	0.2	0.5	0.4	0.3	0.2	0.4	1.0	0.6	0.6
Neuroticism score	0.2	0.5	1.6	0.7	0.5	0.3	0.8	0.7	1.3	0.7	0.3	0.2	-0.7	0.6	1.0	-0.1
Hair/balding pattern: Pattern 3	0.2	0.3	1.0	-0.2	-0.3	-0.5	-0.9	-0.7	-0.1	-1.0	-0.2	-0.1	-0.8	-0.2	0.8	-0.6
Number of live births	0.2	0.3	0.8	-0.5	-0.1	-0.6	-0.5	-0.7	-0.6	-0.6	-0.9	-0.6	0.5	-0.1	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.5	-0.1	0.5	1.6	-0.2	-0.2	-0.4	-0.5	0.1	0.8	1.0	-1.2	-0.4	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.9	-0.3	-0.6	0.3	0.5	0.4	-0.3	-0.1	-0.9	-0.9	-0.8	0.0	-0.6	0.1
Medication: Cholesterol lowering	0.2	0.3	1.0	-0.2	-1.0	-0.8	0.4	0.2	-0.0	-0.4	-0.0	-0.0	0.9	-0.7	-0.4	0.3
Prospective memory result	0.2	0.2	0.7	-0.2	0.6	0.6	-0.1	-0.1	-0.7	-0.4	0.5	0.5	0.3	-0.7	-0.8	0.1
Lung cancer (father)	0.2	0.2	1.0	-0.0	-0.0	-1.0	0.5	0.1	0.2	0.1	0.1	0.0	-0.2	0.7	-0.2	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.3	-0.0	0.7	1.8	0.1	0.2	-0.3	-0.1	0.4	0.8	0.5	-0.9	-0.7	1.5
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	2.2	0.1	1.5	-0.3	-0.2	0.2	0.1	-0.3	0.5	0.4	0.7	-0.7	0.2	-0.1
Blood clot in the leg (DVT)	0.2	0.3	1.1	-0.3	-0.1	-0.0	-0.4	-0.9	-0.8	-1.0	-0.2	-0.2	-0.2	-0.4	0.4	-0.5
Gout (self-reported)	0.2	0.3	1.3	0.1	-1.1	0.1	0.7	0.4	0.1	0.4	-0.2	-0.0	0.7	0.1	-0.5	0.9
Medication: Amlodipine	0.2	0.3	1.2	-0.4	-0.4	-0.8	0.6	0.2	0.3	0.2	-1.1	-0.4	-0.1	-0.4	-0.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.9	-0.2	1.3	-0.5	-0.1	-0.1	-0.2	0.1	-0.3	-0.3	-1.7	-0.4	-0.2	0.0
Average weekly red wine intake	0.2	0.2	1.0	0.2	0.0	1.0	0.3	0.5	0.2	0.2	0.3	0.0	-0.9	0.3	-0.5	0.5
Diabetes diagnosed by doctor	0.2	0.3	1.3	0.3	1.2	-0.9	-0.1	-0.1	0.0	0.0	0.3	0.0	0.6	0.5	0.8	-0.2
Medication for cholesterol	0.2	0.3	1.0	-0.6	-0.8	-0.0	-0.3	-0.2	-0.4	-0.0	-1.0	-0.7	-0.9	-0.2	-0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	0.5	-0.6	0.3	0.5	0.5	0.9	0.6	0.0	0.5	0.1	0.1	0.4	-0.2
Irritability	0.2	0.3	1.8	-0.0	0.7	0.5	0.2	0.1	0.2	-0.2	-0.5	-0.5	-1.3	0.2	0.3	-0.3
Commuting to job workplace: Cycle	0.2	0.3	2.2	0.2	1.5	-0.4	0.1	-0.0	0.2	-0.3	0.1	-0.1	-0.1	0.6	0.1	-0.9
Cholesterol lowering medication	0.2	0.3	0.8	-0.2	0.8	-0.5	-0.3	-0.4	-0.3	-0.6	0.2	0.2	0.8	-0.0	-0.4	0.9
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	-0.4	-0.3	-0.0	-0.2	-0.8	-0.7	-0.9	-0.3	-0.3	-0.2	-0.5	0.4	-0.5
Bipolar Disorder or Schizophrenia	0.1	0.3	1.1	0.3	-0.6	0.4	0.4	0.8	0.5	0.5	0.6	0.7	-0.1	-0.3	-0.1	1.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.9	-0.0	-1.4	0.3	0.2	0.2	0.2	0.6	-0.7	-0.5	-0.9	-0.2	0.1	0.2
Schizophrenia (2018)	0.1	0.2	0.7	-0.0	-0.9	-0.2	0.3	0.3	0.4	0.2	0.1	0.5	-0.3	-0.2	-0.4	0.6
Alzheimer’s Disease (in mother)	0.1	0.2	1.2	-0.2	0.0	0.2	-0.1	0.0	-0.5	0.3	0.6	0.0	0.2	-0.1	-0.5	1.1
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	-0.1	0.3	0.1	-0.2	-0.3	-0.4	0.4	0.0	-0.4	-0.3	0.6	0.2	-0.1
Irritable Bowel Disease (IBD)	0.1	0.2	1.0	0.2	-1.0	0.0	-0.2	0.0	0.1	-0.1	0.7	0.6	-0.6	-0.1	0.2	0.7
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.0	-0.5	-0.8	-0.4	-0.4	-0.4	-0.1	-0.0	-0.8	-0.7	-1.0	-0.6	-0.1	0.2
Prostate Cancer	0.1	0.2	1.5	0.2	1.2	0.2	0.0	-0.1	-0.2	-0.4	0.6	0.6	0.5	0.1	0.0	0.1
Fasting Glucose	0.1	0.1	0.4	0.1	-0.6	-0.4	-0.0	0.1	0.3	-0.2	-0.3	0.0	-0.2	0.1	0.6	0.1
Blood Platelet Count	0.1	1.1	4.6	-0.9	-1.0	-1.9	-1.0	-0.9	-0.2	-0.8	-0.7	-0.4	0.4	-0.8	-0.5	-2.1
Height	0.1	1.7	6.9	0.0	2.5	-0.9	-1.0	-1.2	-0.5	-1.3	0.2	-0.4	0.2	0.5	1.8	-2.6
Systolic Blood Pressure	0.1	0.4	2.4	-0.2	-0.4	-0.9	0.1	-0.3	0.3	-0.2	-0.2	-0.1	1.5	-0.3	-0.5	0.7
Respiratory disease	0.1	0.2	0.4	0.2	-0.4	-0.6	0.5	0.4	0.6	0.3	-0.6	-0.4	-0.1	0.2	0.4	-0.2
Sensitivity / hurt feelings	0.1	0.2	0.5	0.1	0.7	-0.0	0.5	0.4	0.5	0.6	0.2	-0.0	-0.5	-0.4	-0.1	-0.2
Diabetes (father)	0.1	0.1	0.6	-0.1	-0.1	0.5	-0.3	0.1	-0.1	0.4	0.3	0.3	0.3	-0.6	-0.3	0.8
Medication: Levothyroxine sodium	0.1	0.2	0.9	0.4	-0.6	-0.4	0.0	0.3	0.1	-0.0	0.4	0.4	1.0	0.7	0.2	0.3
Sitting height	0.1	0.8	3.6	-0.2	1.9	-0.1	-1.0	-0.9	-0.8	-0.5	-0.0	-0.1	-0.8	-0.1	0.3	-1.7
Allergy	0.1	0.1	0.4	0.2	0.1	0.6	-0.0	0.1	-0.1	0.3	0.5	0.1	0.5	0.5	-0.0	-0.7
Fluid intelligence score	0.1	0.1	0.5	0.1	-0.3	0.2	-0.2	-0.1	0.1	0.1	-0.4	-0.5	-0.4	0.5	0.7	-0.1
Noisy workplace	0.1	0.1	0.3	0.2	0.5	0.4	0.1	-0.2	0.1	-0.3	0.4	0.0	0.5	0.5	0.4	0.4
Standing height	0.1	1.0	5.1	-0.2	2.2	-0.8	-1.1	-1.0	-0.7	-0.8	-0.2	-0.4	-0.7	0.3	0.6	-1.7
Hair/balding pattern: Pattern 4	0.1	0.2	0.9	0.2	-0.3	0.6	0.7	0.5	0.0	1.0	0.4	0.4	-0.5	0.1	-0.5	-0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.2	0.1	-0.8	-0.4	-0.2	0.1	-0.1	0.1	0.1	-0.1	1.1	0.2	-0.1	0.5
Heart disease (mother)	0.1	0.1	0.6	-0.2	0.8	-0.5	-0.2	-0.2	-0.2	-0.3	-0.3	-0.2	0.5	-0.2	-0.1	-0.5
Chest pain or discomfort	0.1	0.2	0.6	0.0	-0.1	-0.0	0.8	0.6	0.4	0.0	-0.3	-0.1	0.2	0.3	-0.8	-0.4
Hypertension (Self-reported)	0.1	0.3	1.0	-0.3	0.0	-1.0	-0.2	-0.4	0.3	-1.0	-0.0	-0.3	0.6	-0.6	0.4	-0.7
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.0	0.2	-0.3	0.2	-0.2	-0.2	0.2	-0.1	-0.1	0.6	0.5	0.0	0.2
Mood swings	0.1	0.3	1.0	-0.5	1.0	0.1	-0.4	-0.5	-0.5	-0.6	-0.4	-0.2	-0.7	-0.4	-0.5	-0.5
Ever had bowel cancer screening	0.1	0.1	0.6	-0.4	0.7	-0.2	-0.2	-0.3	-0.2	-0.6	-0.4	-0.2	-0.2	-0.3	-0.3	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.3	0.2	-1.2	-0.3	0.1	0.4	0.1	-0.0	-0.4	0.1	-0.2	0.0	0.3	-0.4
Medication: Blood pressure	0.1	0.2	1.1	0.3	0.4	0.2	0.1	-0.0	0.4	-0.0	0.6	0.2	1.0	-0.0	0.9	-0.1
High cholesterol (Self-reported)	0.1	0.2	0.5	0.1	0.3	-0.4	0.2	0.1	0.2	-0.2	0.7	0.4	0.6	0.1	-0.3	0.7
Alcohol drinker status: Never	0.1	0.2	0.6	-0.3	-0.5	-0.2	-0.6	-0.4	-0.5	-0.0	-0.2	-0.3	0.8	-0.5	-0.1	0.4
Basal cell carcinoma (self-reported)	0.1	0.2	1.1	0.2	0.1	0.4	0.3	-0.0	0.1	0.1	0.6	0.4	1.1	-0.1	0.2	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.2	0.0
Cardiovascular Disease	0.0	0.1	0.2	-0.3	0.0	-0.1	-0.2	-0.4	0.0	-0.5	0.1	0.0	0.4	-0.3	-0.5	0.3
Hypothyroidism (self reported)	0.0	0.1	0.5	-0.2	-0.7	-0.3	-0.2	0.2	-0.3	0.3	-0.1	-0.2	0.3	-0.2	-0.4	0.3
Hair Pigment	0.0	1.0	5.6	-0.9	-2.4	0.1	-0.4	-0.4	-1.0	0.4	-1.0	-0.8	-0.6	-0.9	-1.1	0.7
Relative age of first facial hair	0.0	0.1	0.6	0.0	-0.4	-0.8	0.0	0.2	0.0	0.5	0.0	0.1	-0.1	-0.1	-0.3	-0.2

Hub : Genes

BID

Models

Trait associations