[Hub]/) : Traits : Whole body fat mass :

chr1:31,494,475-34,063,516

Best TWAS P=1.88e-10 · Best GWAS P=4.01e-12 conditioned to 0.00518

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TMEM54 0.05 0.00 blup 281 0.02 4.5e-03 0.97 -6.1 1.2e-09 -0.03 0.10 0.31 TRUE
2 GTEx Muscle Skeletal FNDC5 0.15 0.16 enet 5 0.16 1.9e-15 -5.64 -5.7 1.5e-08 0.01 0.03 0.97 FALSE
3 GTEx Thyroid BAI2 0.31 0.23 lasso 6 0.22 1.4e-16 6.31 6.4 1.9e-10 0.81 0.11 0.89 TRUE
4 The Cancer Genome Atlas Breast Invasive Carcinoma S100PBP 0.03 0.02 blup 46 0.02 6.6e-06 -5.86 5.4 8.0e-08 -0.02 0.01 0.99 FALSE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma S100PBP 0.06 0.03 blup 48 0.06 6.8e-04 -5.73 6.2 7.6e-10 0.00 0.01 0.81 TRUE
6 The Cancer Genome Atlas Glioblastoma Multiforme S100PBP 0.21 0.15 lasso 5 0.15 2.9e-05 -5.64 5.6 1.7e-08 -0.01 0.01 0.92 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma S100PBP 0.04 0.04 lasso 4 0.04 2.3e-05 -5.90 5.9 3.7e-09 -0.01 0.01 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FNDC5 0.03 0.04 enet 6 0.03 2.9e-04 -5.73 -5.1 3.0e-07 0.03 0.01 0.98 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma S100PBP 0.06 0.06 blup 47 0.05 5.2e-06 -5.90 6.0 1.6e-09 0.02 0.01 0.99 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma COL16A1 0.04 0.03 lasso 4 0.03 5.2e-04 6.39 -5.6 1.6e-08 -0.82 0.02 0.87 FALSE