TWAS hub - TMEM54

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.046	0.020	0.00140	-0.002	0.016	-0.001	0.015	-0.001	6.0e-01	0.0045	4.9e-01	0.0048	5.3e-01
2	GTEx	Thyroid	0.103	0.041	0.00011	0.087	NA	0.071	NA	0.072	3.6e-07	NA	4.2e-06	NA	3.3e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Arm fat-free mass (right)	12.4	63.7	99.4	-10.0	5.3
Arm predicted mass (right)	12.0	61.1	95.8	-9.8	5.1
Arm predicted mass (left)	11.6	58.8	87.0	-9.3	5.5
Arm fat-free mass (left)	11.1	56.3	83.9	-9.2	5.3
Weight	9.8	48.4	67.8	-8.2	5.4
Basal metabolic rate	9.5	52.5	79.6	-8.9	5.0
Impedance of arm (right)	9.0	41.9	69.7	8.3	-3.8
Hip circumference	8.9	38.5	51.0	-7.1	5.1
Whole body fat-free mass	8.9	50.9	79.7	-8.9	4.7
Whole body water mass	8.8	50.2	78.3	-8.8	4.7
Leg fat mass (left)	8.8	34.5	41.6	-6.5	5.2
Leg fat mass (right)	8.6	33.3	41.2	-6.4	5.0
Trunk fat-free mass	8.5	48.8	78.9	-8.9	4.3
Trunk predicted mass	8.3	47.4	76.9	-8.8	4.2
Waist circumference	8.0	29.2	38.7	-6.2	4.4
Impedance of arm (left)	7.9	36.5	58.7	7.7	-3.8
Leg fat-free mass (left)	7.8	41.5	61.5	-7.8	4.7
Leg predicted mass (left)	7.8	41.4	60.5	-7.8	4.7
Whole body fat mass	7.4	30.7	37.0	-6.1	4.9
Body mass index (BMI)	7.3	30.9	40.3	-6.3	4.6
Leg fat-free mass (right)	7.3	38.9	57.9	-7.6	4.5
Leg predicted mass (right)	7.3	39.1	58.1	-7.6	4.5
BMI	7.0	40.5	55.4	-7.4	5.1
Risk taking	6.9	10.1	11.0	-3.3	3.0
Arm fat mass (right)	6.8	28.0	34.1	-5.8	4.7
Arm fat mass (left)	6.7	27.5	33.6	-5.8	4.6
Miserableness	6.5	11.3	14.5	-2.9	3.8
Commuting to job workplace: Public transport	6.1	7.3	11.5	-1.7	3.4
Trunk fat mass	6.0	25.9	30.8	-5.5	4.6
Impedance of whole body	5.9	29.8	48.6	7.0	-3.3
Bipolar Disorder (2011)	5.5	5.3	8.3	-1.6	2.9
Qualifications: None of the above	5.5	11.9	14.4	-3.1	3.8
Diabetes (self-reported)	5.5	8.5	12.2	-3.5	2.2
Leg fat percentage (right)	4.9	17.6	22.5	-4.7	3.6
Medication: Lansoprazole	4.8	5.5	6.2	-2.5	2.2
Leg fat percentage (left)	4.8	17.3	21.6	-4.6	3.6
Hearing difficulty/problems: Yes	4.4	6.7	10.1	-1.8	3.2
HbA1C	4.3	4.8	6.9	-2.6	1.6
Mood swings	3.9	7.0	11.1	-1.7	3.3
Body fat percentage	3.7	14.8	15.4	-3.9	3.8
Taking other prescription medications	3.5	5.4	9.4	-1.2	3.1
Peak expiratory flow (PEF)	3.5	8.2	10.5	-3.2	2.4
Depressed Affect (Nagel 2018)	3.4	7.2	8.4	-2.4	2.9
Ovarian Cancer	3.4	4.5	8.4	0.8	-2.9
Qualifications: nursing, teaching	3.3	5.1	6.0	2.0	-2.4
Supplements: Fish oil (including cod liver oil)	3.3	4.3	5.0	-1.9	2.2
Smoking Status	3.2	7.7	10.0	-3.2	2.3
Trunk fat percentage	3.2	12.7	13.0	-3.5	3.6
Had other major operations	3.1	3.8	6.3	-2.5	1.1
Diabetes diagnosed by doctor	3.1	5.2	5.7	-2.4	2.2
Impedance of leg (right)	3.0	14.4	22.5	4.7	-2.5
Hayfever/allergic rhinitis (self-reported)	3.0	4.0	7.0	2.6	-1.0
Medication: Aspirin	3.0	3.9	4.2	-1.9	2.0
Ulcerative Colitis (UC)	2.9	5.5	9.3	-3.0	1.3
Past tobacco smoking	2.9	5.3	6.1	2.1	-2.5
Medication: Seretide 50 evohaler	2.9	3.4	6.5	-0.4	2.6
Comparative height size at age 10	2.9	15.7	17.8	-4.2	3.7
Arm fat percentage (left)	2.9	11.4	12.0	-3.5	3.3
Medication for cholesterol	2.9	4.4	6.6	-2.6	1.5
Ever smoked	2.9	5.1	5.3	-2.2	2.3
Impedance of leg (left)	2.8	13.4	21.3	4.6	-2.4
Mineral and other dietary supplements	2.8	3.8	4.0	2.0	-1.9
Qualifications: O levels/GCSEs or equivalent	2.7	4.3	4.7	2.0	-2.2
Exposure to tobacco smoke outside home	2.7	3.5	3.7	-1.8	1.9
Loneliness, isolation	2.7	3.7	6.8	-2.6	0.8
Diabetes (mother)	2.6	3.3	6.3	-2.5	0.6
Alcohol intake versus 10 years previously	2.6	3.9	5.9	-2.4	1.4
Medication: Blood pressure	2.6	4.9	7.8	2.8	-1.4
Type 2 Diabetes (T2D) (2018)	2.5	4.6	5.4	-2.3	2.0
Medication: Metformin	2.5	3.5	5.2	-2.3	1.3
Arm fat percentage (right)	2.5	10.0	11.5	-2.9	3.4
Medication: Aspirin	2.5	3.3	3.3	-1.8	1.8
Hypothyroidism (self reported)	2.4	5.6	6.6	-2.6	2.1
Chronotype (morning person)	2.4	5.6	7.2	2.0	-2.7
Medication for hormone replacement therapy	2.4	2.7	3.2	1.8	-1.5
Fluid intelligence score	2.4	5.0	6.8	1.8	-2.6
Exposure to tobacco smoke at home	2.4	2.7	4.7	-2.2	0.9
Hypothyroidism/myxoedema (self-reported)	2.4	4.6	5.1	-2.2	2.0
Shortness of breath walking on level ground	2.4	2.8	2.9	-1.7	1.7
Qualifications: College or University degree	2.4	7.7	8.8	2.6	-3.0
Leg pain on walking	2.4	3.0	4.0	-2.0	1.4
Bilateral oophorectomy (both ovaries removed)	2.3	2.6	3.5	1.9	1.3
Irritability	2.3	3.9	4.5	-1.8	2.1
Body Mass Index (BMI) (2010)	2.2	3.0	4.8	-2.2	1.1
Average weekly spirits intake	2.2	2.7	3.9	-2.0	1.2
Noisy workplace	2.2	2.7	5.1	-0.5	2.3
Medication: Cholesterol lowering	2.2	3.5	5.1	-1.4	2.3
Depression (self-reported)	2.2	2.7	4.7	2.2	-0.7
Illnesses of father: None of the above (group 1)	2.2	2.7	5.4	0.2	-2.3
Tinnitus: Yes, now most or all of the time	2.2	2.6	4.7	-0.7	2.2
Pack years of smoking	2.2	3.2	4.0	-1.5	2.0
Major Depression (MDD)	2.1	2.6	4.9	2.2	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	4.7	-0.9	2.2
Pain all over the body in last month	2.1	2.2	4.5	0.1	2.1
Happiness	2.0	2.4	3.2	1.3	-1.8
Wheeze or whistling in the chest in last year	2.0	3.6	5.9	-1.1	2.4
Diabetes (father)	1.9	2.4	3.0	-1.3	1.7
Relative age voice broke	1.9	2.8	5.2	-2.3	0.7
Smoking status: Previous	1.9	2.9	3.5	-1.5	1.9
Townsend deprivation index at recruitment	1.8	2.5	3.3	-1.3	1.8
Illnesses of mother	1.8	2.3	2.3	-1.5	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.6	9.9	-3.1	-1.1
Birth weight of first child	1.8	3.3	5.5	-1.1	2.4
Supplements: Calcium	1.8	2.0	2.0	-1.4	1.4
Pack years adult smoking proportion	1.7	2.6	3.1	-1.4	1.8
Hayfever, allergic rhinitis or eczema	1.7	3.6	7.2	2.7	-0.2
Medication: Levothyroxine sodium	1.7	2.9	3.6	-1.9	1.5
Sitting height	1.7	12.4	17.9	-4.2	2.6
Nervous feelings	1.7	3.2	3.8	1.6	-1.9
Forced vital capacity (FVC)	1.7	6.4	12.6	-3.5	-0.4
Asthma	1.7	3.3	6.6	0.0	2.6
Standing height	1.7	17.0	27.6	-5.2	2.5
Mouth/teeth dental problems: Loose teeth	1.7	2.0	2.4	-1.3	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.7	6.2	-1.1	-2.5
Age started oral contraceptive pill	1.7	2.1	2.2	1.4	-1.5
Alzheimer’s Disease (in mother)	1.6	1.9	3.5	-0.5	1.9
Number of treatments/medications taken	1.6	2.8	3.5	-1.5	1.9
Father’s age at death	1.6	2.2	2.4	1.4	-1.5
Forced expiratory volume in 1-second (FEV1)	1.6	5.4	8.2	-2.9	-1.6
Length of working week for main job	1.6	1.8	3.4	-1.9	-0.3
Forced vital capacity (FVC), Best measure	1.6	5.8	11.6	-3.4	-0.1
Medication: Allopurinol	1.6	2.1	2.3	-1.4	1.5
Family relationship satisfaction	1.6	2.0	2.8	-1.1	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.2	-1.8	0.4
Unable to work because of sickness or disability	1.6	2.1	3.4	-0.9	1.8
Bipolar Disorder (2018)	1.5	2.4	4.8	-0.0	2.2
Ulcerative Colitis	1.5	2.2	3.5	-1.9	1.0
Supplements: Zinc	1.5	1.6	1.8	1.2	-1.3
Medication: Simvastatin	1.5	2.2	2.3	-1.4	1.5
Gout (self-reported)	1.5	2.0	2.2	-1.5	1.3
Number of full brothers	1.5	1.9	3.5	-1.9	0.6
Asthma (self-reported)	1.5	3.1	6.1	0.1	2.5
Hearing aid user	1.5	1.7	3.0	-0.6	1.7
Verbal and Numeric Reasoning (VNR)	1.4	3.4	4.2	1.6	-2.1
Lung FVC	1.4	7.3	14.3	-0.6	-3.8
Severe depression (siblings)	1.4	1.5	2.4	0.8	-1.6
Maternal smoking around birth	1.4	2.1	3.7	-0.7	1.9
Age when periods started (menarche)	1.4	3.5	6.5	-0.6	-2.6
Serious illness, injury or assault to yourself	1.4	1.7	2.8	1.7	0.9
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.2	-1.8	-0.4
Chronic bronchitis/emphysema (father)	1.4	1.6	2.4	-1.6	0.9
High blood pressure (mother)	1.4	1.9	3.4	1.9	-0.7
Pulse wave Arterial Stiffness index	1.4	1.6	2.4	-0.9	-1.6
Age at first live birth	1.4	2.5	4.7	0.5	-2.2
Suffer from ‘nerves’	1.4	2.2	2.8	1.3	-1.7
Schizophrenia vs Biploar Disorder	1.3	1.7	1.9	1.4	-1.3
Worry (Nagel 2018)	1.3	2.7	3.6	1.4	-1.9
Fasting Glucose	1.3	1.6	1.7	-1.2	1.3
Height	1.3	24.2	29.8	-5.5	4.3
Angina	1.3	1.8	2.2	-1.5	1.1
Supplements: Glucosamine	1.3	1.7	1.8	-1.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	2.1	-1.4	1.4
Medication: Ventolin 100micrograms inhaler	1.3	1.6	2.8	-0.7	1.7
Health satisfaction	1.3	1.7	3.0	1.7	-0.6
Mother’s age at death	1.3	1.6	3.1	1.8	-0.1
Allergy or Eczema	1.2	3.0	6.1	2.5	-0.2
Respiratory disease	1.2	2.7	5.0	0.7	2.2
Number of incorrect matches in round	1.2	1.9	3.7	1.9	-0.4
Qualifications: A levels/AS levels or equivalent	1.2	2.7	2.9	1.6	-1.7
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	2.8	1.1	-1.7
Had major operations	1.2	1.5	2.9	1.7	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	4.9	-2.2	0.3
Average weekly champagne plus white wine intake	1.2	1.7	3.2	-0.3	1.8
Systolic Blood Pressure	1.1	5.5	11.0	3.3	0.3
Ever used hormone-replacement therapy (HRT)	1.1	1.4	1.9	1.4	-1.0
Time employed in main current job	1.1	1.3	1.8	1.3	-0.9
Birth weight	1.1	2.3	2.8	-1.4	1.7
Pulse wave peak to peak time	1.1	1.3	2.3	0.5	1.5
Angina (self-reported)	1.1	1.4	2.1	-1.5	0.8
Relative age of first facial hair	1.0	2.1	3.3	-1.8	0.9
Ever had hysterectomy (womb removed)	1.0	1.1	1.2	-1.1	1.0
Current tobacco smoking	1.0	1.7	2.7	-1.6	0.8
Medication: Amlodipine	1.0	1.4	2.6	1.6	-0.5
Emphysema/chronic bronchitis	1.0	1.1	2.2	-1.5	0.2
Illnesses of siblings: Diabetes	1.0	1.3	1.9	-1.4	0.8
Osteoporosis (self-reported)	1.0	1.3	1.4	-1.2	1.1
Number of self-reported non-cancer illnesses	1.0	1.8	2.1	1.4	1.2
Ever taken oral contraceptive pill	1.0	1.1	2.2	-1.5	0.0
Intelligence (Savage-Jansen 2018)	0.9	2.9	4.1	1.3	-2.0
Blood Eosinophil Count	0.9	6.7	7.7	2.8	2.4
Hand grip strength (left)	0.9	2.3	3.4	-1.1	-1.9
Hair/balding pattern: Pattern 4	0.9	2.2	3.9	0.8	-2.0
Friendships satisfaction	0.9	1.1	2.0	1.4	-0.6
Smoking status: Current	0.9	1.5	2.5	-1.6	0.6
Pain type(s) experienced in last month: Hip pain	0.9	1.1	1.4	-0.9	1.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	1.5	-0.9	1.2
Bipolar Disorder or Schizophrenia	0.8	2.0	4.0	0.1	2.0
Alzheimer’s Disease (including proxy)	0.8	1.2	2.3	-0.2	1.5
Medication: Co-codamol	0.8	0.9	1.9	-1.4	-0.1
Qualifications: CSEs or equivalent	0.8	1.1	2.1	-1.4	-0.1
Medication: Ramipril	0.8	1.0	1.6	0.7	1.3
Prospective memory result	0.8	1.0	1.8	-0.5	-1.4
Blood clot in the leg (DVT)	0.8	1.0	1.0	-1.0	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	1.9	-0.3	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.4	-0.7	-1.2
Number of full sisters	0.8	1.0	1.9	-0.2	-1.4
Ever had prostate specific antigen (PSA) test	0.8	0.9	1.3	-0.7	1.1
Fractured/broken bones in last 5 years	0.8	1.1	1.3	0.9	1.1
Triglycerides	0.7	1.1	1.3	-1.1	0.9
Lung FEV1/FVC ratio	0.7	3.6	3.7	-1.9	-1.9
Fed-up feelings	0.7	1.2	2.3	0.2	1.5
Stomach or abdominal pain in last month	0.7	0.8	1.6	1.3	0.3
Hearing difficulty/problems with background noise	0.7	1.2	2.3	-0.1	1.5
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.5	1.2	0.4
Allergy	0.7	1.6	2.0	-1.4	-1.1
Tense / ‘highly strung’	0.7	1.1	1.8	0.7	-1.3
Overall health rating	0.7	1.4	2.6	0.4	1.6
Age at last live birth	0.7	1.0	1.9	-0.3	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	1.7	-0.0	1.3
Eye problems/disorders: Cataract	0.7	0.8	1.4	-1.2	0.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.0	-0.3	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	1.6	1.3	-0.3
Commuting to job workplace: Cycle	0.7	0.8	1.6	-1.3	0.3
Breast Cancer	0.6	1.4	1.6	-1.0	-1.3
LDL Cholesterol	0.6	0.9	1.8	1.4	0.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.0	-0.6	1.0
Blood Platelet Count	0.6	6.8	11.0	-3.3	1.6
Blood Red Count	0.6	5.8	11.0	3.3	0.8
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.3	-0.7	1.1
Financial difficulties in last 2 years	0.6	0.8	1.6	-1.3	0.3
Neuroticism score	0.6	1.3	2.0	-1.4	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	1.6	-0.5	1.3
Pulse wave reflection index	0.6	0.7	1.3	0.4	-1.1
Osteoarthritis (self-reported)	0.6	0.7	1.2	1.1	0.5
Average weekly beer plus cider intake	0.6	0.8	1.5	-1.2	0.3
Diastolic blood pressure, automated reading	0.6	1.8	2.2	-1.5	1.2
Crohns Disease (2017)	0.5	1.1	1.8	1.3	-0.7
Prostate Cancer	0.5	0.7	1.2	-0.4	-1.1
Crohns Disease (2012)	0.5	0.8	1.5	1.2	-0.4
Neuroticism (2016)	0.5	0.7	0.8	0.8	0.9
Primary Biliary Cirrhosis	0.5	0.7	0.8	0.7	0.9
Cardiovascular Disease	0.5	1.7	2.9	1.7	0.7
Mouth/teeth dental problems: Dentures	0.5	0.8	1.2	-0.6	1.1
Breastfed as a baby	0.5	0.6	1.0	-0.5	-1.0
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.9	0.9	0.5
High blood pressure (siblings)	0.5	0.7	1.1	1.0	-0.5
Comparative body size at age 10	0.5	1.3	2.0	-0.8	1.4
Medication for pain relief, constipation, heartburn	0.5	0.8	1.5	-0.4	-1.2
Neck or shoulder pain in last month	0.5	0.7	1.0	-0.5	1.0
Mean time to correctly identify matches	0.5	1.0	1.8	1.4	-0.5
Alcohol intake frequency.	0.5	1.2	1.7	-0.8	1.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.0	-1.0	-0.4
Medication: Atorvastatin	0.5	0.6	1.0	-0.5	1.0
Heart disease (siblings)	0.5	0.7	1.1	0.5	1.1
Depression (Nagel 2018)	0.4	0.6	0.8	-0.7	0.9
Mean Putamen Volume	0.4	0.4	0.8	0.9	0.2
HDL Cholesterol	0.4	0.6	1.2	0.1	1.1
Average weekly fortified wine intake	0.4	0.4	0.8	0.1	-0.9
Alcohol usually taken with meals	0.4	0.7	1.4	-1.2	-0.2
Mouth/teeth dental problems	0.4	0.6	1.2	0.2	-1.1
Number of live births	0.4	0.6	0.8	0.6	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	0.7	-0.7	0.8
Medication: Blood pressure	0.4	0.7	0.9	-0.9	0.7
Migraine (self-reported)	0.4	0.5	0.8	0.4	-0.9
Heart disease (mother)	0.4	0.5	0.7	0.8	0.6
Chest pain or discomfort	0.4	0.6	0.7	-0.7	0.9
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.6	0.6	0.8
Hypertension (Self-reported)	0.4	1.0	1.8	1.3	-0.5
Illnesses of father: Heart disease	0.4	0.5	1.0	0.0	1.0
Long-standing illness, disability or infirmity	0.4	0.5	0.9	0.4	-1.0
Medication: Gliclazide	0.4	0.5	0.8	-0.4	0.9
Financial situation satisfaction	0.4	0.5	0.9	-0.9	-0.4
Number of operations (self-reported)	0.4	0.6	0.6	-0.8	0.7
Alcohol drinker status: Previous	0.4	0.4	0.7	-0.4	0.8
Neuroticism (Nagel 2018)	0.3	0.6	1.1	-0.4	1.1
Age at First Birth	0.3	0.5	0.9	-1.0	-0.1
Schizophrenia (2014)	0.3	0.7	1.5	-0.0	1.2
Sensitivity / hurt feelings	0.3	0.5	0.6	-0.8	0.6
Systolic blood pressure, automated reading	0.3	0.9	1.2	0.8	1.1
Vitamin and mineral supplements	0.3	0.4	0.7	0.3	-0.8
High blood pressure	0.3	0.9	1.8	1.3	-0.3
Falls in the last year	0.3	0.5	0.7	0.9	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.8	0.1	-0.9
Medication: Paracetamol	0.3	0.5	0.7	0.9	0.5
Medication: Omeprazole	0.3	0.3	0.4	-0.6	0.6
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.5	-0.5	0.7
Ever had bowel cancer screening	0.3	0.3	0.4	0.7	0.4
Myopia	0.3	0.4	0.8	0.9	-0.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.8	-1.4	0.2
Basal cell carcinoma (self-reported)	0.3	0.3	0.6	-0.8	0.3
Schizophrenia (2018)	0.2	0.3	0.6	0.1	0.8
Irritable Bowel Disease (IBD)	0.2	0.6	0.9	-1.0	0.5
Reaction Time	0.2	0.4	0.7	0.8	-0.4
Coronary Artery Disease (CAD)	0.2	0.2	0.2	-0.5	0.5
Lupus	0.2	0.3	0.3	-0.4	0.6
Heel T-Score	0.2	1.7	3.2	0.4	-1.8
Hand grip strength (right)	0.2	0.4	0.4	-0.7	-0.7
Hair/balding pattern: Pattern 2	0.2	0.2	0.2	-0.5	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.6	-0.8	0.4
Illnesses of siblings	0.2	0.3	0.3	-0.5	-0.6
Worrier / anxious feelings	0.2	0.4	0.7	-0.1	-0.8
Hair/balding pattern: Pattern 3	0.2	0.3	0.4	0.6	0.4
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	-0.2	0.7
Loud music exposure frequency	0.2	0.2	0.2	-0.4	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	-0.3	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.2	-0.4	0.5
Average weekly red wine intake	0.2	0.3	0.6	-0.7	-0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	-0.2	-0.7
High cholesterol (Self-reported)	0.2	0.3	0.5	0.7	0.5
Medication: Paracetamol	0.2	0.2	0.4	0.2	0.6
Illnesses of father: High blood pressure	0.2	0.2	0.4	-0.1	0.6
Ever depressed for a whole week	0.2	0.2	0.5	-0.0	0.7
Alzheimer’s Disease (in father)	0.1	0.1	0.1	0.0	0.4
Blood White Count	0.1	0.9	1.9	-0.1	1.4
Waist Hip Ratio (WHR)	0.1	0.3	0.6	-0.2	0.8
Neuroticism	0.1	0.2	0.3	-0.5	0.4
Tanning	0.1	1.0	1.8	-0.3	-1.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.3	-0.2	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	-0.6	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	0.3	0.3
Multivitamins +/- minerals	0.1	0.2	0.2	-0.5	0.3
Medication: Atenolol	0.1	0.2	0.2	-0.5	-0.4
Heart attack	0.1	0.2	0.3	0.3	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.3	-0.2	-0.5
Lung cancer (father)	0.1	0.1	0.3	-0.5	-0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	0.1	-0.4
Glaucoma (self-reported)	0.1	0.1	0.3	-0.5	-0.1
Worry too long after embarrassment	0.1	0.2	0.3	-0.5	0.1
Medication: Ibuprofen	0.1	0.2	0.3	-0.6	-0.1
Pulse rate, automated reading	0.1	0.4	0.6	0.4	0.8
Knee pain experienced in last month	0.1	0.2	0.3	-0.6	0.1
Guilty feelings	0.1	0.1	0.2	-0.2	0.5
Wears glasses or contact lenses	0.1	0.1	0.2	0.3	0.4
Medication: Bendroflumethiazide	0.1	0.2	0.2	0.4	-0.4
Medication: Lisinopril	0.1	0.1	0.1	-0.4	-0.0
Alcohol drinker status: Never	0.1	0.2	0.3	0.1	-0.6
Cholesterol lowering medication	0.1	0.2	0.3	-0.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.2	-0.4	0.4
Pain experienced in last month	0.1	0.1	0.2	-0.4	-0.3
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	0.1	0.4
Rheumatoid Arthritis	0.0	0.0	0.1	-0.1	-0.2
Hair Pigment	0.0	0.7	1.3	0.2	-1.1
Other serious medical condition/disability diagnosed by doctor	0.0	0.1	0.1	-0.1	0.3
Had menopause	0.0	0.0	0.1	-0.1	0.3
Pulse rate	0.0	0.1	0.2	-0.1	0.4
Headache pain in last month	0.0	0.0	0.1	0.1	0.3
Number of children fathered	0.0	0.0	0.0	-0.1	0.2
Eye problems/disorders: None of the above	0.0	0.1	0.1	0.3	-0.2
Supplements: Vitamin C	0.0	0.0	0.1	0.2	-0.1
Commuting to job workplace: Walk	0.0	0.0	0.0	-0.2	-0.1
Back pain experienced in last month	0.0	0.0	0.1	-0.0	0.2
Breast cancer (self-reported)	0.0	0.0	0.0	-0.1	-0.1

Hub : Genes

TMEM54

Models

Trait associations