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chr5:12,225-1,135,834

Best TWAS P=1.13e-08 · Best GWAS P=3.47e-08 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDCD6	0.03	0.02	blup	49	0.02	2.9e-03	5.3	5.7	1.1e-08	0.95	0.02	0.96	TRUE
7	GTEx	Thyroid	CTD-2083E4.5	0.07	0.06	lasso	2	0.04	3.6e-04	5.5	-5.5	3.0e-08	-0.99	0.01	0.98	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	PDCD6	0.07	0.06	enet	5	0.07	2.0e-07	5.5	-5.5	3.3e-08	-0.91	0.01	0.99	FALSE
9	YFS	Blood	PDCD6	0.03	0.03	bslmm	276	0.03	1.6e-09	5.4	5.5	3.8e-08	0.90	0.01	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	SDHA	0.23	0.18	lasso	2	0.17	1.6e-12	5.5	5.5	4.6e-08	0.99	0.01	0.99	FALSE
5	GTEx	Cells Transformed fibroblasts	CTD-2083E4.5	0.09	0.07	lasso	3	0.05	1.2e-04	5.5	-5.5	4.9e-08	-0.99	0.01	0.98	FALSE
2	GTEx	Artery Aorta	PDCD6	0.26	0.17	lasso	4	0.14	2.8e-08	5.5	-5.4	6.1e-08	-0.99	0.01	0.99	FALSE
8	GTEx	Whole Blood	SDHA	0.05	0.01	lasso	5	0.01	3.4e-02	4.6	-5.4	7.9e-08	-0.90	0.03	0.91	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	SDHA	0.06	0.09	lasso	13	0.08	1.8e-08	5.4	5.4	8.0e-08	0.99	0.01	0.98	FALSE
3	GTEx	Brain Frontal Cortex BA9	AHRR	0.32	0.21	lasso	4	0.18	1.6e-05	5.5	5.4	8.6e-08	0.93	0.01	0.92	FALSE
6	GTEx	Nerve Tibial	CCDC127	0.05	0.01	lasso	4	0.02	2.2e-02	4.4	5.3	1.4e-07	0.86	0.04	0.80	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LRRC14B	0.08	0.04	lasso	5	0.03	6.7e-03	5.3	5.3	1.4e-07	0.97	0.01	0.95	FALSE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	AHRR	0.11	0.05	lasso	3	0.07	2.5e-04	5.5	5.2	1.9e-07	0.86	0.01	0.93	FALSE
1	GTEx	Adipose Subcutaneous	SDHA	0.10	0.09	lasso	5	0.07	1.9e-06	5.5	5.2	2.5e-07	0.97	0.01	0.99	FALSE