[Hub]/) : Traits : Whole body fat mass :

chr7:98,341,025-99,827,148

Best TWAS P=1.42e-08 · Best GWAS P=8.51e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CPSF4 0.06 0.06 blup 313 0.07 6.6e-09 -5.7 -5.3 1.4e-07 0.90 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts CPSF4 0.08 0.03 lasso 4 0.03 1.8e-03 -5.2 -5.2 1.5e-07 0.77 0.12 0.71 FALSE
3 GTEx Esophagus Mucosa GS1-259H13.2 0.07 0.07 lasso 3 0.05 1.7e-04 -5.1 5.2 2.0e-07 -0.78 0.16 0.77 FALSE
4 GTEx Lung ZKSCAN5 0.09 0.05 lasso 2 0.03 2.7e-03 -5.2 5.2 2.2e-07 -0.75 0.16 0.63 FALSE
5 GTEx Thyroid GS1-259H13.2 0.26 0.05 enet 30 0.08 7.6e-07 -5.2 5.5 4.8e-08 -0.59 0.22 0.77 FALSE
6 METSIM Adipose GS1-259H13.2 0.04 0.03 lasso 3 0.02 1.4e-03 -5.2 5.2 2.0e-07 -0.74 0.12 0.85 FALSE
7 ROSMAP Brain Pre-frontal Cortex GS1-259H13.2 0.07 0.05 bslmm 305 0.06 6.9e-08 -5.3 5.3 1.2e-07 -0.81 0.12 0.88 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma ZKSCAN5 0.03 0.04 lasso 2 0.03 1.0e-04 -5.7 -5.7 1.4e-08 0.98 0.01 0.99 TRUE