TWAS hub - ARL3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0320	0.0140	3.6e-04	0.028	0.027	0.013	0.028	0.029	2.3e-04	2.5e-04	7.7e-03	2.3e-04	1.8e-04
2	GTEx	Artery Aorta	0.1920	0.0720	7.9e-04	0.074	NA	0.045	NA	0.056	7.0e-05	NA	1.6e-03	NA	4.8e-04
3	GTEx	Brain Cerebellar Hemisphere	0.1460	0.0730	8.3e-03	0.016	NA	0.107	NA	0.069	1.3e-01	NA	1.1e-03	NA	7.7e-03
4	GTEx	Brain Cerebellum	0.2000	0.0740	2.6e-05	0.092	NA	0.072	NA	0.051	1.1e-03	NA	3.7e-03	NA	1.3e-02
5	GTEx	Cells Transformed fibroblasts	0.0740	0.0330	1.7e-03	-0.002	NA	0.035	NA	0.005	5.0e-01	NA	1.2e-03	NA	1.3e-01
6	GTEx	Colon Sigmoid	0.1300	0.0660	8.1e-03	0.096	NA	0.025	NA	0.054	2.8e-04	NA	4.3e-02	NA	5.5e-03
7	GTEx	Esophagus Mucosa	0.1390	0.0710	8.8e-03	0.042	NA	0.053	NA	0.052	8.3e-04	NA	1.9e-04	NA	2.3e-04
8	GTEx	Muscle Skeletal	0.0668	0.0279	3.5e-04	0.051	NA	0.040	NA	0.063	8.3e-06	NA	8.3e-05	NA	8.9e-07
9	METSIM	Adipose	0.0377	0.0215	3.0e-03	0.000	0.007	-0.001	0.009	-0.002	3.7e-01	2.7e-02	5.7e-01	1.4e-02	8.2e-01
10	ROSMAP	Brain Pre-frontal Cortex	0.2410	0.0629	3.9e-16	0.145	0.157	0.159	0.161	0.158	3.8e-18	1.0e-19	6.0e-20	3.9e-20	7.3e-20
11	YFS	Blood	0.3858	0.0534	0.0e+00	0.135	0.180	0.199	0.176	0.194	8.1e-42	1.9e-56	7.0e-63	3.0e-55	3.4e-61
12	TCGA	Breast Invasive Carcinoma	0.0207	0.0101	1.3e-04	0.012	0.023	0.019	NA	0.019	1.2e-03	1.0e-05	8.1e-05	NA	5.7e-05
13	TCGA	Cervical Squamous Cell Carcinoma	0.0910	0.0520	4.5e-03	0.023	0.050	-0.003	NA	0.020	2.6e-02	1.8e-03	4.5e-01	NA	3.5e-02
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0221	0.0121	5.8e-03	0.000	0.014	0.014	NA	0.004	3.3e-01	8.3e-03	9.1e-03	NA	9.7e-02
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0251	0.0155	8.0e-03	0.021	0.011	0.014	NA	0.023	1.8e-03	1.6e-02	9.0e-03	NA	1.1e-03
16	TCGA	Brain Lower Grade Glioma	0.0393	0.0182	7.4e-05	0.005	0.042	0.022	NA	0.022	8.1e-02	1.5e-05	1.5e-03	NA	1.3e-03
17	TCGA	Lung Squamous Cell Carcinoma	0.0381	0.0198	3.5e-04	0.003	0.018	0.015	NA	0.010	1.4e-01	3.1e-03	6.2e-03	NA	2.2e-02
18	TCGA	Prostate Adenocarcinoma	0.0360	0.0190	1.4e-03	0.018	0.026	0.022	NA	0.022	5.0e-03	9.2e-04	1.9e-03	NA	1.9e-03
19	TCGA	Thyroid Carcinoma	0.0640	0.0290	8.2e-06	0.072	0.055	0.052	NA	0.056	1.5e-07	4.7e-06	7.7e-06	NA	3.5e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Bipolar Disorder or Schizophrenia	11.5	28.2	42.6	1.0	6.4	-4.9	-5.5	5.9	6.3	4.9	5.8	0.8	6.5	-5.8	5.5	5.6	4.7	6.5	4.5	4.8	5.0	6.1
Schizophrenia (2018)	9.8	20.3	34.8	0.7	5.7	-4.6	-4.7	5.1	5.3	4.0	4.7	-0.3	5.9	-5.4	4.5	4.6	3.9	5.3	3.7	3.9	3.8	5.1
Schizophrenia (2014)	9.0	19.9	30.5	0.3	5.5	-4.6	-5.1	5.4	5.2	3.8	4.9	0.5	5.5	-5.1	4.5	4.9	3.7	5.4	3.4	3.8	3.8	4.9
Bipolar Disorder (2011)	8.3	8.0	12.7	1.1	3.3	-1.6	-3.1	1.9	3.5	2.6	2.8	1.5	3.3	-3.2	2.7	3.4	2.5	3.6	2.3	2.9	3.2	3.5
Past tobacco smoking	6.4	11.8	47.3	-5.1	0.2	-5.8	-6.8	0.2	0.7	-2.1	0.4	-6.9	1.1	-4.3	-0.6	-1.6	-3.4	0.0	-3.3	-3.4	-3.0	1.0
Smoking Status	6.1	14.6	70.6	4.7	-1.5	6.2	8.4	-0.6	-1.5	2.5	-0.8	7.1	-2.2	5.3	1.4	0.2	3.8	-0.9	3.5	3.5	2.7	-1.4
Allergy or Eczema	6.0	15.8	64.9	-8.1	-2.6	-5.0	-2.7	-1.2	-2.1	-4.0	-0.8	-5.0	-1.8	-3.0	-1.4	-3.6	-5.1	-1.8	-5.7	-5.3	-5.4	-1.6
Migraine (self-reported)	5.7	7.0	11.0	-1.4	-3.3	2.1	1.6	-3.3	-3.0	-2.8	-2.9	-0.9	-3.2	2.0	-2.5	-3.3	-2.7	-3.2	-3.0	-2.6	-2.0	-2.7
Systolic Blood Pressure	5.6	28.1	68.2	1.3	8.3	-3.1	-5.6	8.0	6.6	4.1	5.3	0.4	6.0	-4.3	4.3	6.4	4.4	7.1	4.7	4.6	3.9	5.3
Medication: Atenolol	5.5	6.9	12.4	2.8	2.8	-0.7	-0.4	3.0	2.5	3.0	2.4	1.6	2.6	-0.8	2.5	3.0	3.2	2.9	3.5	3.5	3.1	2.4
Bipolar Disorder (2018)	5.3	8.5	14.0	0.8	3.1	-2.2	-2.9	3.1	3.4	2.9	3.4	1.6	3.1	-2.7	3.2	3.2	2.7	3.7	2.5	2.9	3.2	3.3
Cardiovascular Disease	5.2	17.3	31.9	3.9	5.2	-1.0	-1.8	5.0	4.4	4.2	3.9	3.4	3.3	-1.3	3.5	5.7	4.9	5.1	5.2	5.2	4.5	3.6
Prostate Cancer	4.7	6.6	21.8	-4.7	-0.5	-2.8	-2.4	-1.0	-0.8	-2.9	-1.6	-3.4	-0.9	-2.5	-1.6	-2.1	-3.6	-1.4	-3.9	-3.4	-3.1	-0.8
Coronary Artery Disease (CAD)	4.7	5.6	11.0	0.7	3.3	-2.1	-2.8	2.9	2.9	2.0	2.0	0.4	3.0	-2.5	2.0	2.8	1.7	3.0	1.7	1.9	2.2	2.7
Hand grip strength (left)	4.7	12.3	53.0	3.8	-3.3	6.4	7.3	-2.5	-3.0	-1.0	-4.1	2.9	-2.7	5.1	-3.2	-2.5	-0.3	-3.7	-0.1	-0.6	0.5	-2.9
Ever smoked	4.7	8.2	33.4	4.2	0.3	4.3	5.8	-0.4	-0.1	2.3	0.2	5.3	-0.4	2.7	1.3	1.3	3.4	0.4	3.2	3.4	3.0	-0.2
BMI	4.6	26.6	60.1	-3.7	-6.5	2.5	5.5	-3.1	-6.2	-4.2	-5.1	-1.3	-7.8	5.0	-3.5	-6.7	-4.7	-6.5	-4.5	-5.0	-5.9	-5.6
Hayfever, allergic rhinitis or eczema	4.6	9.9	42.5	-6.5	-1.5	-4.4	-2.6	-1.2	-1.1	-3.1	-0.3	-4.5	-1.1	-3.0	-1.0	-2.3	-4.0	-1.0	-4.4	-3.9	-4.1	-0.8
Systolic blood pressure, automated reading	4.5	13.0	42.6	0.2	5.2	-3.0	-3.7	6.5	4.2	3.0	3.8	0.7	3.4	-2.9	3.4	4.0	3.1	4.5	2.9	3.0	2.3	3.5
Impedance of leg (right)	4.5	21.7	43.7	4.2	6.6	-1.6	-3.8	2.3	5.6	4.1	4.0	0.5	6.4	-4.2	3.4	5.8	4.8	5.5	4.7	4.9	5.8	5.3
High blood pressure	4.4	12.4	21.7	3.1	4.2	-0.6	-1.5	4.7	3.3	3.6	3.1	3.8	2.5	-0.6	3.3	4.5	4.4	4.2	4.5	4.5	3.9	2.7
Major Depression (MDD)	4.1	5.0	9.6	1.9	3.0	-0.1	-2.3	1.8	2.6	2.0	2.1	2.7	2.0	-1.1	1.9	3.1	2.2	2.4	2.5	2.4	2.2	2.4
Impedance of leg (left)	4.1	19.7	39.7	4.1	6.3	-1.6	-3.7	2.3	5.3	4.0	3.9	0.6	5.8	-3.5	3.4	5.5	4.7	5.2	4.7	4.8	5.6	4.9
Worrier / anxious feelings	4.0	7.6	44.5	-3.4	2.4	-4.8	-6.7	2.4	2.0	-0.6	2.1	-3.3	2.4	-3.5	1.7	1.2	-0.8	2.6	-0.7	-0.8	-1.0	1.5
Mouth/teeth dental problems: Loose teeth	4.0	4.8	10.0	0.3	-2.3	2.6	3.2	-1.2	-2.7	-2.0	-3.1	1.5	-2.4	2.6	-2.4	-1.6	-1.7	-2.7	-1.6	-1.5	-1.2	-2.8
Hypertension (Self-reported)	4.0	11.1	20.0	2.6	4.0	-0.8	-1.7	4.5	3.2	3.4	3.0	3.4	2.4	-0.8	3.4	4.2	4.1	4.1	4.2	4.2	3.5	2.6
Hearing difficulty/problems with background noise	3.9	6.2	21.5	4.6	1.0	2.2	2.1	-0.6	1.2	2.8	1.5	3.8	1.3	1.1	1.8	1.8	3.7	1.2	3.8	3.2	3.0	1.3
Vascular/heart problems diagnosed by doctor	3.9	10.7	24.6	-2.8	-4.0	0.7	1.5	-5.0	-3.0	-3.3	-2.7	-3.4	-2.2	0.4	-3.0	-4.1	-4.0	-3.9	-4.1	-4.1	-3.5	-2.4
Impedance of whole body	3.9	19.8	36.5	2.8	6.0	-3.3	-5.1	2.0	5.2	3.5	4.7	-0.0	5.8	-4.6	3.6	5.6	4.2	5.6	4.0	4.3	4.8	5.0
Body Mass Index (BMI) (2010)	3.7	5.1	11.2	-1.3	-3.0	1.5	2.8	-2.0	-2.7	-1.9	-2.3	0.2	-3.3	2.0	-1.2	-3.1	-1.8	-2.6	-1.9	-2.1	-2.2	-2.4
Blood White Count	3.6	26.6	52.7	7.2	4.6	2.8	3.0	3.1	4.3	6.1	3.9	6.4	3.0	0.5	3.7	5.8	7.0	4.5	7.2	7.3	6.8	4.1
Suffer from ‘nerves’	3.6	5.6	11.4	-0.1	3.4	-1.9	-3.2	3.1	2.9	2.2	2.1	-1.0	3.2	-2.8	2.4	2.2	1.6	2.4	1.6	1.6	1.7	2.8
Allergy	3.5	8.0	33.7	5.8	1.7	3.1	2.1	1.3	1.2	3.1	0.7	3.4	1.0	2.7	1.4	2.0	3.8	1.1	4.2	3.7	3.8	0.9
Smoking status: Previous	3.5	5.2	21.4	3.3	0.6	3.7	4.0	0.1	0.2	1.6	0.0	4.6	-0.3	2.5	0.7	1.5	2.4	0.5	2.5	2.6	2.3	-0.2
Worry (Nagel 2018)	3.3	7.0	34.5	-2.4	3.1	-3.0	-5.9	3.2	2.3	0.2	2.0	-4.1	3.2	-3.5	1.8	1.5	0.0	2.6	0.1	0.0	-0.1	1.9
Ulcerative Colitis	3.3	4.8	12.0	3.5	1.5	1.4	1.1	0.2	2.0	2.7	1.7	3.4	1.5	0.6	1.5	2.0	2.7	1.5	2.9	2.8	3.2	1.9
Forced expiratory volume in 1-second (FEV1), predicted	3.2	6.7	31.9	5.6	0.9	1.5	1.9	0.5	1.7	3.0	1.0	2.6	1.2	1.1	0.7	2.1	3.5	1.5	3.7	3.5	4.3	1.8
Hand grip strength (right)	3.1	8.4	39.5	3.2	-2.9	5.0	6.3	-1.4	-2.4	-0.6	-3.6	1.9	-2.2	4.0	-2.8	-2.4	-0.3	-3.2	-0.1	-0.5	0.5	-2.3
Current tobacco smoking	3.1	5.0	26.1	3.4	-0.4	3.1	5.1	-0.1	-0.3	2.0	-0.1	3.8	-0.8	2.3	1.0	0.1	2.7	-0.7	2.5	2.2	2.0	-0.1
Nervous feelings	3.1	5.7	24.0	-1.0	2.9	-2.5	-4.9	2.5	2.4	0.7	1.8	-3.4	3.6	-3.4	1.3	1.9	0.5	2.5	0.6	0.7	0.9	2.1
Hair/balding pattern: Pattern 2	3.1	3.9	6.9	-1.2	-2.3	1.5	0.4	-1.6	-2.0	-2.4	-2.1	-0.5	-1.8	0.9	-2.5	-2.4	-2.6	-2.3	-2.4	-2.6	-2.2	-2.0
Impedance of arm (left)	3.1	14.5	25.0	1.4	4.9	-3.9	-5.0	1.6	4.3	2.7	4.3	-0.2	4.8	-4.5	3.2	4.8	3.2	5.0	2.8	3.3	3.6	4.3
Pulse wave reflection index	3.1	3.8	7.6	0.5	-2.0	2.6	2.1	-2.8	-1.7	-1.8	-2.1	1.1	-2.4	2.1	-2.3	-2.1	-1.8	-2.4	-1.4	-1.7	-1.1	-1.6
Commuting to job workplace: Walk	3.1	3.4	10.9	-0.9	2.0	-2.8	-3.0	3.3	1.8	1.2	1.9	-0.0	1.3	-1.8	1.9	1.8	1.0	2.4	0.7	1.2	0.9	1.5
Smoking status: Current	3.1	5.0	26.8	3.1	-0.8	3.1	5.2	0.0	-0.7	1.8	-0.3	4.0	-1.1	2.6	0.9	0.0	2.4	-0.8	2.2	2.0	1.8	-0.5
Medication: Bendroflumethiazide	3.1	4.7	14.7	3.2	1.8	1.2	0.0	2.2	1.5	2.0	1.6	3.8	0.9	0.8	1.4	2.9	2.7	2.1	3.0	2.7	2.3	1.0
Type 2 Diabetes (T2D) (2012)	3.0	3.4	7.6	1.6	1.5	-0.6	-2.5	-0.0	1.9	1.0	2.6	1.1	2.7	-1.2	1.2	2.8	1.8	2.7	2.0	1.8	1.6	1.7
Medication for hormone replacement therapy	3.0	3.4	6.7	1.2	1.8	-0.6	-1.2	0.4	2.5	1.7	1.8	0.9	2.4	-2.6	1.2	2.3	1.5	2.2	1.2	1.8	2.5	2.5
Maternal smoking around birth	3.0	4.3	25.4	2.4	-1.5	3.5	5.0	-0.4	-1.0	1.0	-0.7	4.0	-1.8	2.5	0.0	-0.2	1.1	-1.2	1.1	1.2	1.0	-0.9
Body mass index (BMI)	2.9	12.5	28.9	-2.9	-4.3	2.3	4.8	-1.9	-4.1	-2.7	-3.1	0.4	-5.4	3.2	-1.9	-4.6	-3.1	-4.1	-3.0	-3.4	-4.2	-3.7
Average weekly champagne plus white wine intake	2.9	4.0	12.6	-1.6	-2.1	0.4	0.3	-3.6	-2.2	-2.4	-1.5	-2.4	-1.5	0.9	-1.8	-2.3	-2.0	-2.1	-1.9	-2.1	-2.3	-2.1
Length of working week for main job	2.8	3.1	11.3	3.4	1.2	2.1	1.2	-0.1	1.7	1.8	1.3	1.7	1.7	-0.0	0.2	2.1	1.9	1.2	2.3	2.0	2.3	1.6
Ever highly irritable/argumentative for 2 days	2.8	3.3	5.8	1.9	2.0	0.5	0.2	0.7	2.0	1.8	2.0	1.6	2.1	-0.6	1.7	2.4	2.3	2.1	2.4	2.2	2.0	1.8
Medication: Lisinopril	2.8	3.7	5.9	2.0	1.9	-0.6	-2.0	2.4	2.2	2.0	2.0	1.2	2.0	-0.9	1.3	2.3	2.1	2.2	2.3	1.9	1.9	2.0
Height	2.7	51.7	289.0	17.0	-0.5	10.3	8.1	-3.9	0.6	4.3	-2.8	11.6	0.3	8.1	-2.9	3.8	6.8	-0.8	7.9	7.0	9.9	0.3
Heart attack	2.7	3.4	12.7	0.8	2.6	-2.0	-0.7	3.6	2.3	1.9	1.2	0.7	1.8	-1.9	1.2	1.9	1.3	1.9	1.3	1.3	1.7	2.4
Medication for cholesterol	2.7	4.1	10.3	-2.2	-2.1	0.3	0.4	-3.0	-2.0	-1.9	-1.1	-2.5	-1.4	0.4	-1.0	-3.2	-2.2	-2.3	-2.1	-2.5	-2.8	-1.6
Heart attack/myocardial infarction (self-reported)	2.7	3.4	13.3	0.8	2.5	-1.9	-0.6	3.6	2.2	1.9	1.4	0.7	1.8	-1.8	1.2	2.0	1.4	2.0	1.4	1.4	1.6	2.3
Sitting height	2.6	18.2	86.9	9.3	2.2	4.6	2.7	0.1	2.3	3.9	0.4	6.9	1.1	3.4	0.3	3.8	4.9	1.5	5.7	5.3	6.3	1.9
Falls in the last year	2.6	3.6	7.7	1.7	1.3	-0.4	0.3	2.8	1.6	2.4	1.9	2.6	0.8	-0.3	2.3	1.9	2.4	1.8	2.4	2.2	2.2	1.6
Standing height	2.6	25.8	139.2	11.8	0.8	6.3	4.5	-2.4	1.9	4.2	-0.1	7.6	1.3	4.1	-0.3	3.4	5.8	0.9	6.4	5.8	7.8	1.8
Medication: Co-codamol	2.5	2.9	8.6	-0.0	1.9	-1.7	-1.3	2.9	1.9	1.7	1.6	0.3	1.6	-1.8	1.8	1.7	1.4	2.3	1.3	1.5	1.3	1.8
Pack years adult smoking proportion	2.5	3.9	8.5	2.4	1.3	1.5	2.4	0.3	1.7	2.9	1.9	2.3	1.0	-0.7	2.1	1.3	2.8	0.9	2.7	2.5	2.1	1.9
Leg fat-free mass (left)	2.5	13.0	41.2	2.2	-4.8	4.8	6.4	-3.2	-3.7	-1.3	-3.6	3.5	-4.9	5.3	-2.9	-3.3	-1.1	-4.2	-0.7	-1.3	-1.0	-3.4
Impedance of arm (right)	2.5	11.6	19.6	1.5	4.4	-3.2	-4.4	1.1	3.8	2.5	3.9	-0.3	4.3	-3.8	2.8	4.4	3.0	4.4	2.7	3.1	3.5	3.9
Arm fat-free mass (left)	2.5	12.9	46.1	3.4	-4.0	5.6	6.8	-2.7	-3.1	-0.6	-3.8	4.1	-4.3	5.6	-2.6	-2.9	-0.2	-4.0	0.2	-0.3	0.1	-3.0
Pack years of smoking	2.5	3.7	8.2	2.4	1.2	1.5	2.3	0.3	1.6	2.9	1.9	2.4	0.9	-0.6	2.1	1.2	2.7	0.8	2.6	2.4	2.0	1.9
Arm predicted mass (left)	2.5	12.6	45.2	3.6	-4.0	5.8	6.7	-2.9	-3.0	-0.5	-3.6	3.9	-4.1	5.6	-2.5	-2.8	-0.1	-3.9	0.4	-0.3	0.2	-2.9
High blood pressure (mother)	2.4	3.3	11.9	-0.9	2.3	-2.8	-2.4	3.5	1.7	1.1	2.1	-1.3	1.3	-1.1	2.0	1.6	1.2	2.4	1.1	1.0	0.5	1.3
Arm fat-free mass (right)	2.4	12.1	44.5	3.9	-3.6	5.7	6.7	-2.4	-2.7	-0.3	-3.6	4.4	-4.0	5.4	-2.5	-2.5	0.1	-3.8	0.5	-0.1	0.5	-2.7
Arm predicted mass (right)	2.4	12.1	43.0	3.9	-3.6	5.7	6.6	-2.6	-2.8	-0.4	-3.7	4.2	-4.0	5.5	-2.6	-2.5	0.0	-3.7	0.5	-0.1	0.4	-2.8
Whole body fat-free mass	2.4	13.6	44.4	3.6	-4.4	5.7	6.7	-3.0	-3.3	-0.7	-3.9	4.1	-4.4	5.9	-2.8	-3.0	-0.3	-4.1	0.2	-0.4	0.0	-3.2
Leg fat-free mass (right)	2.4	12.9	37.7	2.2	-4.8	4.6	6.1	-3.2	-3.8	-1.3	-3.6	3.4	-5.0	5.5	-2.8	-3.3	-1.1	-4.2	-0.7	-1.2	-1.1	-3.5
Whole body water mass	2.4	13.7	44.8	3.6	-4.4	5.8	6.7	-3.1	-3.3	-0.7	-3.9	4.0	-4.4	5.9	-2.8	-3.0	-0.3	-4.1	0.1	-0.5	0.0	-3.2
Leg predicted mass (right)	2.4	13.0	37.8	2.2	-4.8	4.6	6.1	-3.2	-3.8	-1.4	-3.6	3.5	-5.0	5.5	-2.8	-3.3	-1.1	-4.2	-0.7	-1.2	-1.1	-3.5
Heart disease (siblings)	2.4	2.9	6.4	1.7	2.5	-0.1	0.9	2.0	2.1	1.7	1.1	1.9	1.7	-1.6	0.8	1.7	1.6	1.6	1.9	1.9	2.0	1.9
Leg predicted mass (left)	2.3	12.4	40.0	2.2	-4.6	4.7	6.3	-3.1	-3.6	-1.2	-3.5	3.5	-4.8	5.2	-2.7	-3.2	-1.0	-4.1	-0.6	-1.2	-0.9	-3.3
Medication: Blood pressure	2.3	4.3	14.4	2.3	2.3	0.2	-0.2	3.8	1.6	2.0	1.0	2.4	1.0	0.6	1.4	2.8	2.5	2.2	2.7	2.7	2.5	1.0
Basal metabolic rate	2.3	13.0	45.4	3.4	-4.2	5.5	6.7	-3.1	-3.2	-0.7	-3.7	4.0	-4.4	5.6	-2.6	-2.9	-0.3	-3.9	0.2	-0.5	-0.1	-3.0
Reaction Time	2.2	4.1	18.9	-2.5	2.2	-4.4	-3.2	1.9	1.6	0.3	1.3	-2.9	1.3	-3.3	0.6	1.1	-1.0	1.0	-1.2	-0.8	-0.9	1.7
Supplements: Zinc	2.2	2.4	8.2	1.2	-1.4	1.9	2.9	-0.4	-1.4	-0.8	-1.6	2.5	-2.1	2.2	-1.6	-0.7	-0.5	-1.6	-0.3	-0.4	-0.5	-1.6
Diabetes (self-reported)	2.2	3.4	13.6	1.9	-2.1	3.1	3.7	-1.8	-1.7	-0.4	-1.1	2.0	-1.7	3.2	-1.1	-1.4	0.2	-1.5	0.7	-0.1	-0.3	-1.6
Trunk fat-free mass	2.2	12.5	42.2	4.8	-3.5	6.0	6.5	-2.6	-2.5	0.2	-3.5	4.5	-3.5	5.8	-2.3	-2.2	0.7	-3.4	1.2	0.6	1.3	-2.5
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	8.1	2.9	1.4	0.6	-0.0	0.6	1.2	1.5	0.7	1.5	1.6	0.4	0.4	2.6	2.0	1.5	2.3	2.4	2.0	0.9
Medication: Blood pressure	2.2	3.8	6.6	1.2	2.2	-1.2	-1.3	2.5	1.8	1.8	2.3	2.4	1.3	-0.5	2.0	2.4	2.2	2.6	2.5	2.3	1.6	1.5
Supplements: Vitamin C	2.2	2.6	8.3	0.3	-1.4	1.7	2.9	0.2	-1.5	-0.9	-2.0	2.6	-2.3	1.9	-1.8	-0.9	-1.3	-1.9	-1.1	-0.8	-0.6	-1.6
Diabetes diagnosed by doctor	2.2	3.6	14.7	1.9	-2.0	3.4	3.8	-1.8	-1.8	-0.4	-1.3	2.0	-1.8	3.1	-1.0	-1.5	0.2	-1.6	0.6	-0.1	-0.2	-1.7
Weight	2.1	10.5	42.4	2.4	-3.6	4.9	6.5	-2.8	-3.0	-0.6	-2.9	3.8	-4.5	4.8	-1.8	-2.8	-0.2	-3.4	0.1	-0.5	-0.5	-2.7
Hip circumference	2.1	8.9	33.3	0.3	-3.5	3.6	5.8	-2.9	-3.1	-1.2	-2.8	2.4	-4.6	3.8	-1.6	-3.3	-1.3	-3.6	-1.1	-1.5	-1.8	-2.7
Trunk predicted mass	2.1	12.3	41.7	4.7	-3.5	5.9	6.5	-2.5	-2.5	0.2	-3.5	4.4	-3.5	5.7	-2.2	-2.3	0.7	-3.4	1.1	0.5	1.2	-2.5
Leg fat mass (right)	2.1	8.2	33.8	0.5	-3.1	3.8	5.8	-2.6	-2.9	-1.2	-2.6	2.7	-4.2	3.6	-1.6	-3.0	-1.0	-3.3	-0.8	-1.4	-1.6	-2.6
Medication: Aspirin	2.1	2.8	6.1	1.9	2.0	-0.5	0.1	1.8	1.5	1.7	1.1	2.5	1.5	-0.4	1.0	2.1	1.9	1.6	2.2	2.1	1.9	1.4
Ever taken oral contraceptive pill	2.1	2.3	4.6	0.1	-1.8	1.7	1.8	-1.8	-1.6	-1.6	-2.1	-0.5	-1.2	0.9	-2.1	-1.6	-1.6	-1.8	-1.6	-1.5	-0.6	-1.4
Leg fat mass (left)	2.1	8.4	33.4	0.3	-3.2	3.7	5.8	-2.5	-3.1	-1.2	-2.6	2.7	-4.4	3.7	-1.5	-3.1	-1.0	-3.3	-0.8	-1.4	-1.7	-2.7
Type 2 Diabetes (T2D) (2018)	2.0	3.7	13.5	2.7	-2.0	3.0	3.7	-1.2	-1.7	0.0	-1.1	2.3	-1.8	3.5	-1.1	-0.7	0.8	-1.4	1.3	0.6	0.3	-1.7
Severe depression (siblings)	2.0	2.2	6.4	-0.5	2.1	-1.0	-2.0	1.0	2.0	0.8	1.6	0.2	1.6	-2.5	1.5	1.7	0.9	2.0	0.8	1.0	1.0	1.8
Trunk fat mass	2.0	8.5	29.4	0.8	-3.2	3.7	5.4	-3.0	-3.2	-1.5	-2.6	3.1	-4.3	3.9	-1.9	-2.8	-1.1	-3.2	-0.8	-1.5	-1.6	-2.8
Arm fat mass (right)	2.0	8.2	24.1	-0.7	-3.5	2.8	4.9	-2.5	-3.3	-1.8	-2.7	1.8	-4.5	3.4	-1.6	-3.4	-1.7	-3.3	-1.5	-2.0	-2.4	-2.9
Exposure to tobacco smoke outside home	2.0	2.6	9.9	2.8	-0.6	2.6	3.1	-0.4	-0.2	1.4	-0.1	2.2	-0.1	1.7	0.7	0.2	1.9	0.2	2.0	1.8	1.8	-0.1
Medication: Aspirin	2.0	2.6	4.8	1.6	1.9	-0.9	-0.3	1.8	1.6	1.6	1.3	2.1	1.4	-0.5	1.1	1.9	1.8	1.7	2.2	2.0	1.8	1.5
Alzheimer’s Disease (in mother)	1.9	2.2	5.4	-0.8	-2.3	0.3	-0.3	-1.0	-1.8	-1.7	-1.5	-0.1	-1.8	1.6	-1.6	-1.3	-1.6	-1.6	-1.8	-1.5	-1.4	-1.8
Stomach or abdominal pain in last month	1.9	2.3	4.0	-0.3	-1.7	0.7	1.6	-1.3	-1.7	-1.9	-2.0	0.9	-1.4	1.0	-1.9	-1.4	-1.6	-1.8	-1.6	-1.8	-1.4	-1.7
Waist circumference	1.9	6.8	26.1	1.3	-2.7	4.5	5.1	-2.3	-2.5	-0.8	-2.3	2.9	-3.6	3.6	-1.7	-2.2	-0.5	-2.8	-0.1	-0.7	-1.0	-2.3
Qualifications: College or University degree	1.9	6.0	18.7	1.1	2.5	-3.3	-4.3	0.4	2.6	1.3	3.2	-0.5	3.1	-3.0	1.6	2.8	1.5	3.1	1.7	1.6	1.7	2.7
Whole body fat mass	1.9	7.7	29.6	0.5	-3.1	3.5	5.4	-2.6	-3.0	-1.3	-2.5	2.8	-4.2	3.5	-1.6	-2.9	-1.0	-3.1	-0.8	-1.4	-1.6	-2.6
Illnesses of father: Heart disease	1.9	2.7	7.0	2.0	2.1	-0.7	-0.4	2.6	1.8	1.5	0.5	1.5	1.2	-0.6	0.5	2.1	1.6	1.5	1.7	2.0	2.5	1.6
Arm fat mass (left)	1.9	7.6	25.9	-0.5	-3.4	2.9	5.1	-2.2	-3.1	-1.5	-2.5	2.3	-4.4	3.2	-1.4	-3.2	-1.4	-3.2	-1.3	-1.8	-2.1	-2.7
Diastolic blood pressure, automated reading	1.9	5.8	12.2	3.2	3.4	0.0	-0.2	3.5	2.5	2.5	1.5	2.6	1.0	0.6	1.2	2.9	3.0	2.2	3.4	3.0	2.7	1.8
Alzheimer’s Disease (including proxy)	1.8	2.6	4.4	-0.7	-2.1	0.4	-0.4	-1.3	-1.9	-2.0	-1.8	-0.4	-2.0	1.6	-1.9	-1.4	-1.8	-1.9	-1.8	-1.8	-1.6	-1.9
Time employed in main current job	1.8	2.0	3.3	-1.1	-1.4	-0.2	-1.0	-0.9	-1.5	-1.5	-1.4	-1.3	-1.5	1.5	-1.6	-1.4	-1.6	-1.8	-1.5	-1.6	-1.8	-1.6
Hair/balding pattern: Pattern 3	1.8	2.6	6.7	2.0	2.1	-0.2	0.2	1.0	1.6	1.6	0.8	2.6	1.1	-0.3	1.1	2.0	1.9	1.7	2.0	2.1	2.2	1.4
Medication for pain relief, constipation, heartburn	1.8	3.0	11.2	-0.2	-2.2	1.7	1.5	-1.8	-2.7	-1.4	-1.6	-1.1	-2.1	3.4	-0.6	-1.6	-0.4	-1.6	-0.7	-0.7	-1.3	-2.7
Comparative height size at age 10	1.8	9.7	51.1	7.2	-0.6	5.1	3.7	-2.3	0.0	1.4	-1.5	5.5	0.1	3.7	-1.5	0.8	2.4	-0.9	3.0	2.4	4.0	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	6.6	1.1	1.1	-0.4	-0.4	2.3	1.4	1.8	1.0	2.6	0.7	-0.4	1.5	1.4	1.6	1.4	1.6	1.8	1.9	1.3
Mineral and other dietary supplements	1.8	2.4	10.9	-0.5	1.9	-2.3	-2.9	0.6	1.4	0.3	0.6	-3.3	2.4	-2.2	0.6	0.6	0.4	1.3	0.4	0.3	0.3	1.3
Illnesses of father: None of the above (group 1)	1.8	2.2	7.4	-1.0	-2.6	-0.5	-0.9	-2.7	-1.7	-1.3	-0.3	-1.9	-1.3	1.3	-0.5	-1.7	-1.1	-1.2	-1.3	-1.5	-1.4	-1.4
Schizophrenia vs Biploar Disorder	1.7	2.2	6.1	-1.2	2.2	-1.3	-1.9	2.5	1.8	1.2	1.6	-0.8	1.3	-2.1	1.6	1.1	0.7	1.5	0.5	0.6	0.6	1.8
Crohns Disease (2012)	1.7	2.8	8.7	2.9	-0.2	2.7	2.4	0.6	-0.0	1.4	0.4	3.0	-0.1	2.1	0.9	0.6	2.1	0.4	2.0	1.7	1.9	-0.1
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	5.1	0.5	2.3	-1.1	-0.8	1.1	2.1	1.3	1.4	0.5	1.7	-2.1	0.9	2.1	1.0	2.0	1.1	1.3	1.5	2.0
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	10.6	1.9	0.1	2.9	3.3	-0.5	-0.0	1.0	0.0	1.6	0.3	1.1	0.2	0.4	1.3	-0.0	1.4	1.3	1.4	0.1
Medication: Metformin	1.7	2.4	10.0	0.7	-2.0	2.2	3.2	-1.1	-1.9	-0.9	-1.1	0.6	-1.5	2.2	-0.9	-1.9	-0.4	-1.5	-0.1	-0.7	-0.8	-1.8
Bilateral oophorectomy (both ovaries removed)	1.7	2.0	5.9	-2.4	1.9	-2.4	-2.4	2.0	1.2	0.1	0.1	-1.2	0.4	-2.3	1.0	0.0	-0.4	1.0	-0.7	-0.0	0.1	1.2
Forced vital capacity (FVC)	1.7	6.4	23.8	4.9	2.0	1.5	1.9	1.6	2.2	2.9	0.2	1.4	1.4	0.5	0.6	2.4	3.1	1.4	3.1	3.7	4.7	2.1
Arm fat percentage (right)	1.7	6.6	16.9	-2.1	-3.0	1.6	4.0	-2.0	-3.2	-2.0	-2.0	0.8	-4.1	2.4	-1.1	-3.3	-1.9	-2.8	-1.9	-2.3	-3.0	-2.7
Asthma	1.7	3.3	7.0	-2.5	-1.6	0.6	0.3	-0.9	-1.7	-2.2	-1.8	-0.5	-1.9	0.5	-1.8	-1.5	-2.4	-1.9	-2.6	-2.5	-2.5	-1.8
Medication: Amlodipine	1.7	2.3	5.7	-0.6	1.4	-2.0	-1.6	2.0	1.2	1.1	2.4	-0.2	0.9	-0.8	2.1	1.7	1.5	2.4	1.4	1.5	0.6	1.1
Angina (self-reported)	1.7	2.3	4.0	1.6	1.9	-0.3	0.1	2.0	1.5	1.3	1.1	2.0	1.3	-0.5	1.1	1.7	1.6	1.8	1.8	1.8	1.8	1.2
Illnesses of father: High blood pressure	1.7	2.0	5.8	0.7	2.1	-0.8	-0.2	2.4	1.5	1.6	1.4	0.7	0.9	-0.6	1.7	1.6	1.6	1.8	1.7	1.7	1.0	1.2
Mouth/teeth dental problems: Dentures	1.6	2.7	8.1	0.5	-1.9	2.4	2.8	-1.4	-1.8	-0.6	-1.3	1.9	-2.0	2.5	-0.7	-1.7	-0.4	-1.8	-0.4	-0.8	-0.9	-1.7
Exposure to tobacco smoke at home	1.6	1.8	4.9	0.3	0.6	-1.2	-0.0	1.7	1.2	1.9	2.2	1.3	0.7	-0.4	2.0	1.3	1.5	1.3	1.6	1.7	0.7	1.2
Birth weight	1.6	3.6	10.7	0.9	-2.8	1.1	2.3	-2.7	-2.4	-0.7	-2.2	1.9	-2.3	3.3	-0.8	-2.1	-0.2	-2.3	-0.5	-0.2	0.1	-2.1
Blood Eosinophil Count	1.5	11.9	29.5	4.3	3.9	0.4	-1.4	0.6	3.8	3.0	3.2	4.0	4.2	-2.0	1.2	5.4	3.3	3.8	3.9	4.0	4.2	3.6
Number of incorrect matches in round	1.5	2.5	9.1	-1.7	1.6	-2.1	-3.0	1.4	1.7	-0.5	0.9	-1.4	1.6	-3.0	-0.2	0.8	-1.4	1.1	-1.2	-1.2	-0.7	1.4
Headache pain in last month	1.5	2.5	5.5	-2.0	-1.1	-0.7	0.3	-1.2	-1.2	-1.6	-2.0	-1.0	-1.7	0.3	-1.3	-2.0	-2.1	-1.8	-2.4	-2.3	-1.6	-1.2
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	3.9	-1.7	-1.4	-0.7	0.3	-1.9	-1.6	-1.8	-1.0	-0.7	-1.1	0.2	-0.8	-1.5	-1.6	-1.1	-2.0	-1.7	-1.8	-1.3
Illnesses of siblings: Diabetes	1.5	1.8	5.3	1.5	-1.8	1.6	1.5	-2.2	-1.6	-1.2	-0.6	2.0	-0.9	2.3	-1.1	-0.2	0.1	-0.6	0.2	-0.2	-0.3	-1.8
Leg fat percentage (left)	1.5	5.5	17.8	-1.2	-2.3	2.4	4.2	-1.8	-2.6	-1.4	-2.1	1.3	-3.8	2.5	-0.9	-3.0	-1.4	-2.8	-1.3	-1.8	-2.4	-2.3
Ever depressed for a whole week	1.5	1.8	5.9	2.4	0.8	1.1	-0.3	-0.2	1.2	1.0	1.2	1.8	1.2	0.1	0.0	2.2	1.6	1.1	1.7	1.3	1.8	1.1
Commuting to job workplace: Cycle	1.5	1.8	3.4	1.5	1.3	-0.3	-1.0	0.9	1.6	1.6	1.5	-0.1	1.5	-1.1	1.4	1.1	1.6	1.4	1.8	1.4	1.6	1.7
Blood Platelet Count	1.4	16.1	70.4	7.3	1.8	3.9	3.3	-0.6	2.3	3.3	2.3	8.4	1.6	1.1	-0.0	5.1	4.3	2.1	4.6	4.8	5.3	2.1
Neuroticism	1.4	3.5	14.3	-2.5	2.1	-2.0	-3.8	2.3	1.3	-0.1	1.4	-3.0	2.3	-2.4	1.7	0.8	-0.1	2.0	-0.1	-0.2	-0.4	1.0
Number of treatments/medications taken	1.4	2.6	10.4	0.9	2.0	0.3	-0.4	2.0	2.1	1.3	1.3	3.2	1.3	-1.9	0.7	1.8	1.0	1.6	1.4	1.3	1.6	1.8
Hearing difficulty/problems: Yes	1.4	2.2	12.2	3.0	-0.3	1.1	1.0	-0.3	0.2	1.6	0.4	3.5	0.1	1.6	0.6	0.9	1.8	-0.0	1.9	1.5	1.4	0.2
Peak expiratory flow (PEF)	1.4	3.2	16.0	3.3	-0.6	3.0	4.0	-0.0	-0.2	1.5	-0.8	1.0	-0.6	2.3	0.0	-0.3	1.7	-0.5	1.9	1.7	2.1	-0.0
Forced vital capacity (FVC), Best measure	1.4	5.1	18.8	3.9	1.8	0.5	0.8	1.9	2.1	3.0	0.2	0.2	1.7	0.1	1.0	2.0	2.9	1.2	2.8	3.3	4.3	2.3
Pulse wave peak to peak time	1.4	1.6	8.0	2.8	-1.0	1.6	1.6	-1.3	-0.6	0.9	-0.3	0.2	0.0	1.6	0.1	0.2	1.7	-0.4	1.6	1.6	1.6	-0.5
Arm fat percentage (left)	1.4	5.5	15.1	-2.3	-2.7	1.1	3.7	-1.6	-2.9	-1.8	-1.8	0.8	-3.9	1.9	-0.8	-3.0	-1.8	-2.5	-1.9	-2.2	-2.9	-2.4
Financial situation satisfaction	1.4	1.7	5.4	2.3	-0.3	1.5	1.4	-0.3	0.0	1.5	0.5	1.0	-0.3	2.1	1.0	0.7	2.0	0.2	2.0	1.8	1.4	0.2
Fractured/broken bones in last 5 years	1.4	1.8	5.7	-1.2	1.6	-2.0	-1.8	1.4	1.5	0.5	1.6	-0.2	1.3	-2.4	1.3	1.4	0.5	1.7	0.4	0.6	0.2	1.3
Alcohol drinker status: Previous	1.4	1.6	2.8	1.1	1.2	-1.0	-1.0	0.6	1.4	1.7	1.2	0.4	1.5	-1.2	1.5	1.2	1.5	1.1	1.5	1.3	1.3	1.6
Ever had hysterectomy (womb removed)	1.3	1.5	4.9	-2.2	-0.5	-0.5	-1.2	-0.6	-0.7	-1.6	-0.9	-1.4	-0.7	-0.4	-0.7	-1.4	-1.7	-0.8	-1.9	-1.5	-1.4	-0.7
Taking other prescription medications	1.3	2.1	5.2	0.4	1.8	-0.2	-0.7	1.0	1.7	1.2	1.9	2.3	1.2	-1.5	1.4	1.8	1.3	1.8	1.4	1.2	1.2	1.6
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	6.8	-2.6	-1.0	-1.7	-1.8	-0.6	-0.3	-1.0	0.5	-2.5	0.3	-1.6	0.0	-0.5	-1.1	0.0	-1.4	-1.3	-1.4	-0.1
Medication: Simvastatin	1.3	1.9	4.8	0.6	-1.8	0.3	2.2	-0.3	-1.7	-1.3	-1.6	1.5	-1.8	1.5	-1.7	-1.0	-0.9	-1.5	-0.7	-1.1	-1.1	-1.7
Birth weight of first child	1.3	2.4	9.6	0.6	-2.4	0.8	1.8	-1.7	-1.9	-0.0	-1.3	0.5	-2.3	3.1	-0.3	-1.9	0.0	-2.2	0.1	-0.2	-0.7	-1.6
Leg fat percentage (right)	1.3	4.8	17.3	-1.0	-2.0	2.5	4.2	-1.8	-2.4	-1.3	-2.1	1.1	-3.4	2.0	-1.0	-2.8	-1.4	-2.6	-1.2	-1.7	-2.2	-2.0
Age at first live birth	1.3	2.4	4.2	-1.3	-1.8	-0.2	-1.2	-1.0	-2.0	-1.7	-1.2	-1.6	-1.7	1.7	-1.2	-1.7	-1.6	-1.7	-1.3	-1.4	-1.9	-2.0
Mean time to correctly identify matches	1.3	2.5	8.6	-1.0	2.3	-2.9	-2.4	2.1	1.8	1.2	1.1	-0.9	1.4	-2.4	0.8	1.5	0.0	1.0	-0.0	0.3	0.2	1.9
Heart disease (mother)	1.3	1.6	3.9	0.5	1.6	-1.1	-1.3	1.2	1.6	0.7	1.5	1.1	2.0	-1.8	0.7	1.6	0.9	1.6	0.8	0.6	1.0	1.3
Mean Putamen Volume	1.2	1.4	3.6	1.6	-1.4	1.5	0.9	-1.4	-1.1	-0.8	-0.9	1.9	-1.3	1.9	-1.3	-0.6	-0.6	-1.3	-0.5	-0.8	-0.1	-1.0
Angina	1.2	1.6	3.0	1.6	1.4	-0.1	0.4	1.6	1.1	1.1	0.8	1.7	1.0	-0.1	0.9	1.3	1.5	1.4	1.7	1.6	1.5	0.9
Trunk fat percentage	1.2	4.8	13.8	-0.8	-2.3	2.0	3.7	-2.5	-2.5	-1.7	-1.7	1.9	-3.6	2.3	-1.3	-2.3	-1.4	-2.3	-1.3	-1.8	-2.1	-2.2
Townsend deprivation index at recruitment	1.2	1.7	8.9	1.7	-0.6	2.0	3.0	-0.9	-0.4	0.6	0.3	2.6	-0.4	0.9	0.7	0.2	1.3	0.1	1.3	1.2	0.9	-0.4
Age at last live birth	1.2	1.8	3.8	-0.5	-1.5	0.9	-0.0	-1.1	-1.9	-1.7	-1.4	0.0	-1.8	1.6	-1.5	-1.2	-1.3	-1.5	-1.0	-1.0	-1.3	-1.9
Knee pain experienced in last month	1.2	1.9	13.9	0.0	-1.1	1.6	3.2	0.2	-1.0	-0.1	-0.7	3.7	-1.7	1.3	0.1	-0.5	-0.1	-0.6	-0.2	0.0	-0.1	-0.9
Friendships satisfaction	1.2	1.4	2.9	-1.4	-1.3	-1.0	-1.7	-1.4	-1.5	-1.1	-0.6	-1.3	-1.6	1.2	0.1	-1.2	-0.7	-0.8	-0.8	-0.7	-1.6	-1.4
Asthma (self-reported)	1.2	2.5	6.0	-2.4	-1.3	0.4	0.1	-1.0	-1.3	-2.0	-1.3	-0.5	-1.5	0.1	-1.5	-1.1	-2.1	-1.5	-2.4	-2.3	-2.2	-1.4
Number of self-reported non-cancer illnesses	1.2	2.1	6.1	-0.3	1.3	-0.8	-1.4	1.9	1.6	1.1	2.0	2.5	1.0	-1.6	1.3	1.9	1.0	1.7	0.9	1.1	0.9	1.4
Medication: Atorvastatin	1.2	1.5	3.2	0.3	1.8	-0.6	-1.2	1.6	1.6	1.0	0.9	-0.6	1.4	-1.2	1.0	1.2	1.0	1.6	1.0	1.2	1.5	1.4
Ever had prostate specific antigen (PSA) test	1.2	1.4	3.6	-1.9	-1.0	-0.8	-0.4	-0.6	-1.1	-1.5	-0.5	-1.5	-0.9	-0.3	-0.7	-1.3	-1.5	-0.8	-1.6	-1.7	-1.9	-1.1
Basal cell carcinoma (self-reported)	1.2	1.4	5.1	1.8	0.8	1.2	-0.2	-0.5	1.3	1.1	1.0	2.2	1.5	-0.7	0.4	1.2	1.0	0.9	1.0	1.0	1.5	1.4
Irritable Bowel Disease (IBD)	1.1	2.7	12.3	2.7	0.4	2.3	1.5	0.4	0.7	1.7	0.4	3.5	0.4	1.7	0.6	0.9	1.8	0.4	1.8	1.7	2.3	0.6
Waist Hip Ratio (WHR)	1.1	5.1	24.9	5.0	1.0	3.6	-0.0	0.2	1.3	1.4	0.7	2.4	2.1	1.0	-0.9	2.8	2.4	1.3	3.0	2.6	3.2	0.9
Pain all over the body in last month	1.1	1.1	5.4	-0.8	1.2	-1.1	-0.5	2.3	1.3	1.4	1.0	-0.1	0.8	-1.2	1.5	0.7	0.6	0.8	0.4	0.6	0.4	1.4
Qualifications: A levels/AS levels or equivalent	1.1	2.5	10.0	3.2	1.1	-0.2	-1.8	-0.9	1.3	1.3	1.8	0.2	1.6	-0.2	0.3	2.4	1.8	1.3	2.1	1.7	1.9	1.4
Breastfed as a baby	1.1	1.4	3.5	-0.7	1.6	-0.5	-1.9	1.2	1.2	0.9	1.3	-1.1	1.7	-1.4	1.4	0.9	0.8	1.4	0.8	0.9	0.8	1.2
Body fat percentage	1.1	4.4	15.5	-1.0	-2.1	2.1	3.9	-2.1	-2.4	-1.3	-1.5	1.6	-3.4	2.1	-0.8	-2.4	-1.2	-2.2	-1.0	-1.6	-2.1	-2.0
Commuting to job workplace: Car/motor vehicle	1.1	1.3	5.0	-0.6	-1.5	1.0	2.2	-0.8	-1.2	-0.6	-0.9	-0.3	-1.5	1.2	-0.7	-1.3	-0.7	-1.6	-0.9	-0.8	-1.0	-1.1
Long-standing illness, disability or infirmity	1.1	1.7	4.1	1.8	1.4	1.0	1.2	-0.3	1.1	1.5	0.5	1.7	0.8	-0.1	1.1	0.9	1.7	0.9	2.0	1.8	1.8	1.1
Alzheimer’s Disease (in father)	1.0	1.1	2.4	-0.6	-0.4	0.4	0.3	-0.8	-0.8	-1.2	-1.5	-0.1	-1.3	0.2	-1.6	-1.1	-1.4	-1.4	-1.2	-1.4	-1.1	-0.9
Respiratory disease	1.0	2.3	7.4	-2.7	-1.3	-0.2	-1.3	-0.8	-0.9	-2.0	-0.8	-1.1	-0.7	-0.6	-1.4	-1.0	-2.1	-0.9	-2.4	-2.2	-2.1	-0.9
Relative age of first facial hair	1.0	2.0	4.3	2.1	1.3	1.3	0.1	-0.7	1.6	1.6	1.1	1.1	1.1	-0.4	1.0	1.9	1.7	1.5	1.6	1.8	2.0	1.5
Diabetes (father)	1.0	1.3	5.8	0.2	-1.1	2.4	2.1	0.1	-1.3	-0.5	-0.8	1.2	-0.9	2.0	-0.3	-0.9	0.0	-0.7	0.1	-0.0	-0.5	-1.5
Diabetes (mother)	1.0	1.3	5.6	2.3	0.0	2.4	1.2	-1.1	0.2	0.3	0.5	1.8	0.8	0.6	-0.3	0.9	1.1	0.7	1.4	1.1	1.3	-0.1
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	2.7	-1.1	-1.1	0.3	-0.5	-0.9	-1.2	-1.4	-1.0	1.0	-1.6	0.7	-0.5	-0.9	-1.0	-1.0	-1.2	-1.0	-1.0	-1.3
Neuroticism score	1.0	2.2	8.8	-2.0	1.3	-1.8	-3.0	1.9	0.9	-0.1	0.9	-2.2	2.0	-1.9	1.4	0.8	0.1	1.6	-0.1	-0.1	-0.0	0.7
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	12.6	3.5	1.6	1.3	2.6	1.3	1.5	2.1	-0.5	0.2	0.9	0.4	0.3	1.3	2.1	0.8	2.2	2.6	3.4	1.6
Happiness	1.0	1.2	2.3	-1.3	-1.1	0.2	-0.7	-0.9	-1.1	-1.5	-1.3	-0.2	-1.1	0.4	-0.8	-1.2	-1.5	-0.8	-1.4	-1.3	-1.2	-1.0
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	3.6	-1.9	-0.4	-0.4	-0.8	-0.5	0.2	-0.9	-0.6	-1.5	-0.5	-1.7	-1.1	-0.8	-1.9	-0.8	-1.9	-1.7	-0.9	0.3
Average weekly red wine intake	1.0	1.5	4.9	0.1	1.4	-2.0	-2.2	1.6	1.3	0.6	1.4	-0.2	1.4	-0.9	0.7	1.4	0.6	1.7	0.8	0.8	0.5	1.1
Number of operations (self-reported)	1.0	1.5	3.6	-1.1	-1.1	1.0	-0.3	-1.9	-1.1	-1.7	-1.2	0.4	-1.3	0.6	-1.0	-1.3	-1.6	-1.2	-1.6	-1.4	-1.2	-1.1
Risk taking	1.0	1.5	5.2	0.7	0.6	0.4	1.4	1.7	0.7	1.5	0.9	2.3	-0.3	0.1	1.5	0.8	1.5	1.1	1.3	1.7	1.5	0.7
Neuroticism (Nagel 2018)	0.9	2.0	11.2	-1.7	1.6	-1.2	-3.3	1.7	1.1	-0.3	1.0	-1.7	1.7	-1.9	0.7	1.0	-0.3	1.5	-0.1	-0.4	-0.6	0.7
Crohns Disease (2017)	0.9	2.0	9.5	1.8	-0.2	3.1	2.2	0.6	-0.4	0.7	-0.5	2.7	-0.6	2.4	0.1	0.0	1.1	-0.2	1.1	1.0	1.1	-0.6
Vitamin and mineral supplements	0.9	1.3	8.0	-0.3	0.7	-2.1	-2.8	0.1	0.5	-0.1	1.0	-1.9	1.6	-0.9	0.8	0.6	0.5	1.1	0.4	0.2	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	7.5	2.0	0.8	0.2	-0.8	-0.4	1.6	1.2	1.3	0.4	2.7	-1.6	0.0	1.8	1.1	1.4	1.4	1.4	2.1	1.7
Alcohol usually taken with meals	0.9	1.5	10.3	-1.3	0.3	-2.0	-2.5	-0.2	-0.0	-0.9	-0.2	-3.2	0.5	-1.1	-0.2	-0.5	-0.9	0.4	-0.9	-0.6	-0.6	-0.0
Had other major operations	0.9	1.1	3.2	-0.9	-0.6	-0.4	-0.5	-0.7	-1.3	-1.8	-1.4	0.5	-1.3	0.6	-1.0	-0.7	-1.4	-0.8	-1.3	-1.0	-1.2	-1.4
Mouth/teeth dental problems	0.9	1.3	4.4	-0.2	1.4	-1.6	-2.0	0.3	1.2	0.3	0.4	-2.1	1.7	-1.9	0.1	0.8	-0.0	0.9	-0.1	0.1	0.7	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	10.6	2.8	1.5	0.2	1.4	1.5	1.6	2.3	-0.0	-0.7	1.1	0.1	0.9	1.1	2.2	0.9	2.2	2.5	3.3	1.8
Pulse wave Arterial Stiffness index	0.9	1.0	4.2	-2.1	0.9	-1.1	-1.3	1.0	0.6	-0.8	0.3	0.3	0.1	-1.4	-0.3	0.0	-1.4	0.4	-1.3	-1.3	-1.1	0.6
Wheeze or whistling in the chest in last year	0.9	1.7	4.1	-0.5	-1.7	0.8	1.3	0.0	-1.3	-1.0	-1.0	1.7	-2.0	1.6	-1.1	-1.0	-1.1	-1.6	-1.1	-1.3	-1.3	-1.4
Neck or shoulder pain in last month	0.9	1.3	4.8	0.1	2.2	-0.3	0.8	0.7	1.6	1.1	0.7	1.0	0.9	-1.5	0.9	1.3	1.0	1.0	0.8	1.1	1.2	1.4
Medication: Omeprazole	0.9	1.0	2.4	1.2	0.8	0.2	-0.0	0.6	1.1	0.7	1.2	1.6	1.4	-0.9	0.6	1.4	0.9	1.3	0.9	0.9	1.2	1.0
Ever had bowel cancer screening	0.9	1.0	4.8	1.9	0.5	1.0	0.6	0.0	0.4	1.0	-0.0	2.2	0.2	1.0	-0.2	0.9	1.0	0.2	1.2	1.2	1.4	0.3
Back pain experienced in last month	0.9	1.3	6.0	1.2	0.8	0.9	2.0	0.5	0.6	1.3	0.0	2.5	-0.6	0.7	1.1	0.3	1.4	0.3	1.4	1.3	1.3	0.5
Medication: Paracetamol	0.9	1.4	5.1	0.4	1.9	-0.4	-0.9	1.0	1.9	0.7	0.5	1.5	1.6	-2.3	0.2	1.1	0.1	0.9	0.3	0.4	0.9	1.7
Unable to work because of sickness or disability	0.9	1.2	2.3	1.0	1.2	-0.3	0.0	0.8	1.3	1.5	0.9	0.1	1.0	-0.6	1.2	0.9	1.5	1.1	1.5	1.4	1.4	1.3
Ulcerative Colitis (UC)	0.8	1.4	7.8	2.2	0.3	1.0	0.9	-0.6	0.6	1.3	0.2	2.8	0.2	1.1	0.5	0.5	1.2	-0.1	1.2	1.2	1.9	0.7
Ovarian Cancer	0.8	1.1	3.8	0.7	-0.5	1.9	1.2	-1.3	-0.7	-0.8	-0.6	1.4	-1.3	1.3	-1.7	0.2	-0.7	-1.1	-0.5	-0.7	-1.0	-0.8
Fasting Glucose	0.8	0.9	3.5	1.5	-0.4	1.4	1.9	0.2	-0.8	0.8	0.0	1.1	-0.4	1.8	0.6	-0.3	1.0	-0.7	0.9	0.4	0.1	-0.7
Blood Red Count	0.8	8.0	18.1	1.4	4.3	-0.7	-0.9	0.5	3.8	2.3	2.5	1.9	3.4	-3.2	2.5	3.1	2.9	3.8	2.6	2.9	3.7	3.5
Relative age voice broke	0.8	1.3	2.4	1.3	1.1	0.7	0.0	0.4	1.0	1.5	0.8	1.5	0.6	0.3	1.3	1.2	1.6	1.0	1.5	1.6	1.4	0.9
Qualifications: CSEs or equivalent	0.8	1.0	3.7	0.2	-1.1	1.0	1.9	-1.0	-1.1	-0.9	-1.3	0.9	-0.9	1.1	-1.0	-0.9	-0.5	-1.1	-0.6	-0.6	-0.4	-1.2
Qualifications: None of the above	0.8	1.7	6.6	-0.3	-0.6	2.4	2.6	0.9	-1.1	-0.3	-2.0	0.3	-1.7	1.7	-0.3	-1.5	-0.5	-1.4	-0.6	-0.5	-0.4	-1.2
Medication: Ramipril	0.8	1.1	4.0	-0.0	1.6	-1.3	-2.0	1.2	1.1	0.1	0.8	1.0	1.3	-1.2	0.1	1.3	0.2	1.4	0.4	0.5	0.3	0.7
Illnesses of siblings	0.8	1.1	10.2	-1.7	-0.5	-0.9	-1.3	-0.9	-0.3	-0.3	0.6	-3.2	0.6	-0.8	0.2	-0.7	-0.8	-0.2	-0.7	-0.8	-1.1	0.1
Pulse rate	0.8	1.4	4.4	-2.1	1.0	-1.6	-1.6	1.3	1.0	0.5	1.7	-0.9	1.0	-1.7	1.4	0.7	0.1	1.2	-0.3	-0.1	-0.4	1.1
Lung cancer (father)	0.8	0.9	5.7	0.8	-1.1	1.0	0.1	-2.4	-0.7	-0.4	-0.4	1.8	-0.9	1.2	0.3	-1.1	0.2	-0.7	0.1	-0.1	-0.1	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	6.2	1.3	1.3	0.9	-0.1	0.3	1.2	0.2	0.8	2.5	1.0	-0.7	-0.2	1.9	0.5	1.1	0.8	0.7	1.0	0.8
Medication: Paracetamol	0.8	1.4	5.9	-0.0	1.9	-0.1	-0.6	0.9	2.0	0.5	0.7	1.9	1.4	-2.4	0.2	1.0	-0.1	1.0	0.2	0.2	0.7	1.7
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.0	-0.5	-0.8	0.6	0.2	-0.5	-0.9	-1.4	-1.0	-0.4	-0.6	0.6	-1.7	-0.2	-1.6	-1.1	-1.4	-1.4	-1.4	-1.0
Number of full brothers	0.8	1.0	2.3	0.7	1.0	0.4	1.2	1.1	0.6	1.1	0.5	0.9	0.2	-0.2	1.4	0.7	1.5	0.9	1.5	1.4	1.0	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	3.5	-0.5	1.7	-0.7	-1.6	1.9	1.2	0.4	0.4	-0.0	0.8	-1.2	0.5	1.4	0.3	1.1	0.1	0.4	0.6	0.9
Eye problems/disorders: None of the above	0.8	0.9	2.5	-1.5	-0.9	-0.8	0.5	-0.9	-0.7	-0.8	-0.0	-0.8	-1.6	-0.1	-0.0	-1.4	-1.2	-0.9	-1.2	-1.1	-1.3	-0.4
Medication: Ibuprofen	0.8	0.9	2.3	-1.0	-0.3	0.0	-0.3	-1.0	0.1	-0.9	-0.9	-1.4	-0.4	-1.1	-1.2	-0.9	-1.5	-1.0	-1.5	-1.5	-0.7	0.2
Guilty feelings	0.8	1.2	2.6	-1.3	-0.6	-0.6	-1.4	-0.4	-0.8	-1.6	-1.0	-1.3	-0.4	-0.1	-1.2	-0.7	-1.6	-0.7	-1.2	-1.3	-1.4	-1.0
Chronotype (morning person)	0.7	1.5	5.6	-1.5	-1.0	-0.6	-0.2	-1.5	-1.1	-0.9	-1.0	-1.7	-1.9	1.0	0.2	-2.4	-0.9	-1.1	-1.1	-1.1	-1.2	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	4.8	-0.9	1.3	-2.0	-1.7	1.1	0.7	0.1	-0.4	-2.2	0.4	-1.2	1.0	0.1	0.3	0.8	0.0	0.4	0.6	0.7
Illnesses of mother	0.7	0.8	2.1	-0.6	-1.0	0.9	0.8	-1.1	-0.9	-0.5	-0.9	0.5	-1.2	0.4	-0.8	-1.0	-1.0	-1.4	-0.8	-0.8	-1.0	-0.6
Tense / ‘highly strung’	0.7	1.2	6.0	-0.8	1.6	-0.6	-1.1	2.5	0.7	0.6	0.2	-1.0	0.7	-0.7	1.7	0.4	0.9	1.3	0.7	1.2	0.8	0.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.1	1.2	0.3	-0.9	-1.6	1.0	0.7	1.1	1.1	0.4	0.7	0.2	0.9	1.8	1.3	1.2	1.4	1.3	1.1	0.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.9	-0.8	-0.7	0.3	-0.2	-2.2	-0.4	-0.7	-0.9	-2.1	0.2	-0.6	-0.9	-1.1	-1.2	-1.2	-1.4	-1.2	-0.7	-0.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.9	0.5	2.0	-1.0	-1.5	0.4	1.7	1.0	0.9	0.6	1.4	-1.3	0.7	1.4	0.9	1.2	0.9	1.1	1.2	1.5
High blood pressure (siblings)	0.7	1.1	6.9	1.7	1.0	0.4	-0.2	1.1	0.9	0.8	-0.1	2.6	0.2	0.6	0.4	1.0	1.1	0.6	1.0	0.9	1.3	0.5
Worry too long after embarrassment	0.7	1.2	6.2	-1.4	0.8	-1.2	-2.5	1.9	0.6	-0.3	0.9	-1.9	0.9	-1.3	0.3	0.9	-0.4	0.9	-0.3	-0.3	-0.5	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	6.1	0.7	0.6	1.0	2.5	0.6	0.0	-0.1	-0.1	2.3	-0.1	0.3	-0.4	0.8	0.5	0.4	0.5	0.8	0.5	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	3.6	1.8	-0.0	1.9	1.0	-1.2	0.1	0.3	0.6	1.4	0.3	0.6	-0.0	0.7	0.8	0.0	1.1	0.6	0.2	0.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.3	0.2	-1.6	1.1	1.4	-0.7	-1.4	-0.9	-0.4	0.8	-0.8	1.8	-1.0	-0.4	-0.4	-0.8	-0.2	-0.7	-1.1	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.8	1.5	-0.2	0.6	1.7	0.6	-0.5	-0.1	-1.5	1.4	-0.4	1.0	-1.4	0.4	-0.0	-0.8	0.3	0.2	0.6	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	20.6	-0.7	1.0	-0.8	-0.5	0.5	0.6	0.6	-0.7	-4.5	0.5	-1.2	0.4	-1.1	-0.1	-0.6	-0.2	-0.1	0.3	1.0
Pain type(s) experienced in last month: Hip pain	0.7	0.8	5.5	-2.4	-0.4	-0.6	0.5	0.7	-0.6	-0.6	-0.1	0.2	-1.0	-0.1	0.6	-1.0	-0.8	-0.3	-1.2	-1.2	-1.4	-0.8
Age at First Birth	0.6	0.9	4.2	-0.1	-1.3	0.3	-0.4	-2.0	-0.7	-0.1	-0.5	-0.3	-1.3	0.9	-0.7	-1.3	-0.7	-1.8	-0.6	-1.0	-1.0	-0.3
Neuroticism (2016)	0.6	0.9	4.8	-2.2	0.2	-1.1	-1.2	0.9	-0.4	-1.0	-0.5	-0.3	-0.5	-0.6	-0.4	-0.1	-1.2	-0.2	-1.1	-1.1	-1.6	-0.6
Supplements: Glucosamine	0.6	0.8	6.8	0.3	-0.9	1.4	0.9	-0.1	-0.5	-0.0	-0.1	2.6	-1.4	1.1	-0.1	-0.0	-0.1	-0.5	-0.1	0.0	0.2	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	5.4	2.3	0.2	1.0	-0.5	-1.1	1.0	0.6	0.9	1.1	2.2	-0.9	-0.6	1.4	0.8	0.9	1.3	1.1	1.7	1.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.5	0.5	0.7	0.1	-0.7	0.4	0.9	1.0	1.1	0.5	0.5	-0.1	0.9	1.2	1.1	0.8	1.2	1.2	0.9	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	5.1	1.7	0.1	1.0	2.3	-0.7	0.1	0.9	-0.4	1.6	-0.1	0.8	0.5	0.1	1.3	-0.0	1.3	1.0	1.2	0.2
Alcohol intake frequency.	0.6	1.4	6.4	1.8	0.0	1.9	2.5	0.1	-0.1	1.1	-1.1	1.2	-0.9	1.5	0.5	-0.6	1.1	-0.6	1.2	0.9	1.4	0.1
Irritability	0.6	1.0	4.5	0.6	-0.8	1.6	2.1	-0.9	-0.9	-0.0	0.0	1.4	-0.9	2.0	0.3	-0.4	0.6	-0.4	0.6	0.3	-0.0	-1.0
Myopia	0.6	0.8	2.4	-0.8	-1.3	-0.4	-0.4	-0.2	-1.4	-1.0	-0.2	-0.5	-1.6	1.6	-0.4	-0.3	-0.7	-0.5	-0.7	-0.4	-1.1	-1.4
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.3	1.9	-0.7	-1.1	-1.5	-2.1	0.3	1.2	1.7	1.3	0.4	0.9	0.9	1.1	1.7	0.5	1.8	1.4	1.0	0.6
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.7	1.2	-0.5	-1.3	-0.9	-1.6	0.1	1.1	1.5	0.4	0.3	0.6	1.3	0.6	1.6	0.7	1.6	1.3	0.7	0.4
Lupus	0.5	0.7	2.8	0.2	-1.2	0.7	0.6	-1.7	-0.8	-0.3	-1.1	-0.1	-1.1	0.9	-0.5	-1.1	-0.3	-1.3	-0.5	-0.5	0.0	-0.5
Primary Biliary Cirrhosis	0.5	0.8	2.7	1.6	0.8	0.3	1.2	1.5	1.0	0.9	0.6	0.1	0.9	0.1	-0.2	1.0	0.7	0.6	0.8	0.8	1.2	0.7
Rheumatoid Arthritis	0.5	0.7	3.2	1.4	0.3	1.1	1.8	0.6	0.4	1.1	-0.0	0.5	-0.0	0.5	0.5	0.0	1.1	0.3	1.1	1.1	1.1	0.4
Lung FVC	0.5	2.5	12.4	-2.0	1.9	-2.4	-0.2	3.3	1.1	0.7	-0.5	-3.5	0.8	-2.1	0.7	0.3	-0.3	0.3	-0.9	0.2	0.5	1.1
Average weekly fortified wine intake	0.5	0.5	1.8	-0.4	-0.6	-0.5	-0.7	-0.1	-0.4	-1.2	-0.5	-0.1	-0.1	-0.3	-1.3	-0.1	-1.3	-0.3	-1.1	-1.0	-1.0	-0.5
Age when periods started (menarche)	0.5	1.1	5.1	1.2	-0.5	2.0	1.8	-0.9	-0.1	0.6	0.9	2.3	-0.0	0.8	0.4	0.7	0.9	0.5	0.8	1.1	1.1	-0.0
Had menopause	0.5	0.6	2.6	-1.6	0.7	-1.6	-1.0	0.4	0.5	-0.0	0.3	-0.3	0.6	-1.5	0.7	0.1	-0.3	0.3	-0.6	-0.3	-0.3	0.6
Financial difficulties in last 2 years	0.5	0.7	2.6	1.6	-0.3	1.1	1.5	0.4	-0.2	0.8	-0.4	0.7	-0.4	1.5	0.0	0.0	1.0	-0.3	1.1	0.7	0.6	-0.2
Fluid intelligence score	0.5	1.0	3.3	1.4	-0.8	-1.1	-1.1	-1.8	-0.1	0.7	1.2	-0.9	1.0	0.2	0.9	0.2	1.4	0.6	1.4	0.9	0.9	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.5	0.4	0.8	0.3	-0.4	0.9	1.2	0.9	1.1	0.2	0.8	-0.6	0.2	1.0	0.7	0.7	0.9	0.8	0.8	1.1
Medication: Lansoprazole	0.5	0.6	1.6	-0.8	0.8	-0.7	-0.9	1.3	0.9	0.5	1.0	1.0	0.1	-1.0	0.8	0.6	0.2	0.6	0.1	0.2	-0.2	0.7
Prospective memory result	0.5	0.6	1.4	0.1	-0.6	1.1	0.4	0.1	-0.8	-0.6	-0.9	0.3	-0.9	1.2	-1.0	-0.6	-0.6	-0.8	-0.5	-0.9	-0.9	-0.9
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.0	1.4	0.2	1.3	-0.0	-0.7	0.2	0.6	-0.1	0.8	0.2	0.7	0.5	0.4	1.0	0.3	1.0	1.2	1.2	0.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	4.2	0.5	-0.7	2.1	0.6	-1.2	-0.6	-0.4	-0.6	-0.2	-0.3	1.0	-0.7	-0.9	-0.4	-0.9	-0.2	-0.6	-0.4	-0.6
Supplements: Fish oil (including cod liver oil)	0.5	0.6	6.4	0.2	-0.7	0.7	1.4	-0.1	-0.4	0.1	0.3	2.5	-1.1	0.6	-0.1	0.3	-0.0	-0.3	-0.1	0.2	-0.0	-0.3
Supplements: Calcium	0.5	0.5	3.0	-0.3	-0.6	-0.1	1.7	0.1	-0.7	-0.5	-0.5	0.3	-1.5	0.6	-0.7	-0.5	-0.4	-0.8	-0.6	-0.5	-0.6	-0.7
Breast Cancer	0.4	1.0	6.5	-1.1	0.5	-1.8	-2.6	0.9	0.7	0.3	1.2	-1.1	0.2	-0.8	1.3	-0.1	0.1	0.5	0.0	-0.1	-0.2	0.8
Average weekly spirits intake	0.4	0.5	2.4	1.1	0.3	1.6	0.7	0.6	0.8	0.8	0.1	0.9	0.6	-0.7	-0.2	0.8	0.4	0.3	0.1	0.3	1.1	0.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.4	0.8	1.1	-0.4	-1.2	-0.2	0.9	0.3	-0.1	-0.6	1.1	-0.8	0.7	0.8	0.6	0.9	0.5	0.6	1.1	0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.4	-0.8	0.0	0.4	-1.0	-0.4	-0.1	-1.1	-0.4	0.5	-0.3	-0.4	-0.9	0.4	-1.2	-0.3	-1.2	-0.8	-0.7	-0.2
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.1	-1.0	0.0	-1.5	-1.5	0.3	0.3	-0.4	0.1	-0.6	0.7	-1.4	-0.0	0.1	-0.5	0.2	-0.9	-0.6	0.1	0.4
Medication: Levothyroxine sodium	0.4	0.7	2.1	-0.9	1.4	-1.4	-1.1	0.5	0.9	0.4	0.4	-0.6	0.7	-1.1	1.0	0.3	0.3	0.9	0.1	0.4	0.2	0.8
Alcohol intake versus 10 years previously	0.4	0.6	2.2	0.4	-0.1	1.1	0.8	0.9	-0.1	1.1	-0.5	1.0	-1.5	1.1	0.5	-0.4	0.7	-0.4	0.6	0.7	0.6	0.0
Depression (self-reported)	0.4	0.5	1.5	-0.6	-0.0	0.4	1.2	-0.4	-0.6	-1.0	-1.2	0.4	-0.7	0.0	-0.8	-0.5	-0.9	-0.4	-0.7	-0.9	-0.7	-0.8
Loud music exposure frequency	0.4	0.4	1.6	1.3	0.2	0.7	0.9	1.2	0.3	0.7	-0.2	0.3	0.5	0.4	-0.3	0.5	0.4	-0.2	0.2	0.4	1.1	0.3
Blood clot in the leg (DVT)	0.4	0.5	1.9	-1.0	0.3	-0.8	-1.2	0.7	0.3	-0.2	0.5	-1.4	0.6	-1.1	-0.2	-0.0	-0.6	0.4	-0.3	-0.5	-0.5	0.3
Comparative body size at age 10	0.4	1.0	4.1	0.2	-1.4	1.4	2.0	0.8	-1.2	0.8	0.2	0.7	-1.3	1.9	0.7	-0.9	0.6	-0.8	0.4	0.1	-0.6	-0.7
Shortness of breath walking on level ground	0.4	0.5	1.9	-1.1	-0.7	-0.3	0.5	0.3	-0.6	-0.6	-0.2	0.2	-0.7	0.3	-0.1	-0.9	-0.7	-0.4	-0.6	-1.0	-1.4	-0.7
Medication: Allopurinol	0.4	0.6	2.2	1.5	0.6	0.3	-0.6	0.1	0.8	0.9	0.5	0.7	0.8	-0.0	0.1	1.0	0.9	0.5	1.2	0.9	0.8	0.6
Pulse rate, automated reading	0.4	1.2	2.8	-1.3	1.5	-0.9	-1.4	-0.1	1.1	0.4	1.4	-1.1	1.4	-1.7	1.5	0.7	0.5	1.3	0.1	0.1	0.1	1.2
Number of full sisters	0.4	0.5	1.7	-0.1	-1.0	1.1	0.7	-1.3	-0.7	-0.6	-0.4	0.0	-0.3	0.6	-0.8	-0.5	-0.4	-0.6	-0.4	-0.5	-0.4	-0.7
Overall health rating	0.4	0.9	3.6	-0.9	-0.3	1.1	1.9	-0.9	-0.7	-0.4	-0.7	0.5	-1.8	0.9	0.4	-1.3	-0.3	-0.9	-0.3	-0.4	-0.9	-0.8
Qualifications: nursing, teaching	0.4	0.7	3.9	1.4	-0.3	1.0	-0.3	-1.4	-0.3	-0.7	-0.0	2.0	-0.3	0.7	-1.3	0.7	-0.3	-0.2	0.1	-0.1	-0.1	-0.5
Eye problems/disorders: Cataract	0.4	0.4	1.9	0.4	-0.5	0.9	-0.5	-0.4	-0.5	-0.7	-1.0	-0.9	0.2	0.4	-1.4	0.0	-0.5	-0.4	-0.5	-0.6	-0.2	-0.7
Osteoarthritis (self-reported)	0.4	0.5	4.0	-0.6	-0.1	-0.1	0.7	2.0	0.1	0.3	-0.2	1.9	-0.8	0.1	0.0	0.4	-0.4	-0.2	-0.4	-0.1	-0.1	-0.0
Medication: Gliclazide	0.4	0.5	3.4	0.6	-0.3	0.8	1.9	0.4	-0.5	-0.0	-0.5	0.7	-1.1	0.9	-0.4	-0.9	0.1	-0.7	0.4	-0.1	-0.3	-0.5
Commuting to job workplace: Public transport	0.4	0.4	3.7	0.4	0.8	-0.3	-1.9	-0.6	0.4	-0.1	0.2	-0.7	1.0	-0.4	0.0	0.5	0.2	0.6	0.4	0.1	0.4	0.5
Cholesterol lowering medication	0.4	0.6	2.8	0.5	0.9	-0.8	-0.1	1.7	0.8	0.7	0.0	1.1	0.5	-0.6	0.1	1.0	0.6	0.9	0.7	0.8	1.0	0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.2	0.7	0.5	-0.1	-0.1	0.9	0.9	0.5	1.0	1.1	0.8	-0.9	0.5	0.8	0.5	0.8	0.3	0.5	0.9	0.9
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.8	-1.0	0.5	-1.1	-1.3	0.7	0.4	-0.2	0.5	-1.4	0.7	-1.3	-0.1	0.0	-0.6	0.5	-0.3	-0.4	-0.4	0.4
HbA1C	0.3	0.3	1.4	-0.7	0.7	-0.6	-1.2	0.6	0.5	0.1	-0.1	-0.3	0.5	-1.1	0.2	0.3	-0.3	0.5	-0.4	-0.1	0.1	0.5
HDL Cholesterol	0.3	0.6	3.9	-0.1	0.5	-1.1	-0.9	0.3	0.6	0.3	0.5	-2.0	1.2	-1.2	0.5	-0.0	0.1	0.4	-0.1	-0.2	0.2	0.8
LDL Cholesterol	0.3	0.5	1.1	-1.0	-0.7	0.9	0.9	0.0	-0.5	-0.6	-0.7	0.3	-0.5	0.1	-0.4	-0.9	-0.8	-0.7	-1.0	-1.0	-0.7	-0.5
Triglycerides	0.3	0.5	3.7	0.4	0.9	0.7	0.8	-0.2	0.5	0.0	0.5	1.9	0.3	-0.2	0.2	0.6	0.4	0.7	0.5	0.6	0.3	0.3
Heel T-Score	0.3	2.5	20.3	1.8	-2.1	1.9	-0.9	-4.5	-0.8	-1.5	-0.5	0.6	1.0	0.1	-2.4	-0.5	-1.2	-0.9	-0.7	-1.2	0.1	-0.5
Lung FEV1/FVC ratio	0.3	1.7	15.3	-0.7	-0.6	0.7	3.9	-0.2	-0.7	0.5	-1.1	-1.1	-1.5	0.3	0.8	-2.6	0.1	-1.2	0.0	-0.5	-0.8	-0.2
Sensitivity / hurt feelings	0.3	0.5	2.3	-0.7	0.1	0.4	-0.9	-0.3	-0.5	-1.5	-0.3	-0.9	0.7	-0.3	-0.9	0.3	-0.9	0.3	-0.6	-0.9	-0.8	-0.8
Multivitamins +/- minerals	0.3	0.4	1.6	-0.4	-0.4	1.0	1.1	-0.2	-0.4	-0.3	-0.6	0.7	-1.3	0.2	-0.5	-0.3	-0.7	-0.7	-0.7	-0.2	-0.1	-0.2
Medication: Cholesterol lowering	0.3	0.5	1.5	0.1	-0.6	-0.3	1.2	0.9	-0.9	-0.6	-0.4	0.9	-1.2	0.9	-0.4	-0.4	-0.1	-0.3	-0.1	-0.2	-0.5	-1.0
Health satisfaction	0.3	0.3	1.9	0.3	-0.4	1.4	0.5	-1.0	-0.2	-0.0	0.1	0.7	-0.9	0.9	-0.0	-0.2	0.1	-0.5	0.3	-0.0	-0.4	-0.3
Emphysema/chronic bronchitis	0.3	0.3	1.6	0.7	-0.5	1.0	1.3	-0.1	-0.1	0.3	-0.1	1.1	0.2	0.2	-0.1	0.4	0.4	-0.2	0.3	0.3	0.3	-0.0
Had major operations	0.3	0.4	2.3	-0.2	-0.5	1.5	1.1	-1.0	-0.5	-0.1	-0.4	0.3	-0.7	0.6	0.2	-0.6	-0.1	-0.4	-0.2	-0.2	-0.2	-0.3
Family relationship satisfaction	0.3	0.4	1.3	0.4	0.3	-0.3	-0.6	-0.1	-0.5	-0.0	-0.2	0.2	-0.8	1.1	0.8	0.4	0.9	0.6	1.0	1.1	0.3	-0.6
Osteoporosis (self-reported)	0.3	0.4	0.7	-0.6	-0.5	0.6	-0.3	0.7	-0.4	-0.5	-0.5	-0.4	-0.4	0.3	-0.7	-0.4	-0.6	-0.8	-0.7	-0.7	-0.8	-0.6
Miserableness	0.3	0.5	2.9	1.2	-0.5	0.9	1.7	-1.1	-0.3	-0.0	-0.5	1.0	-0.1	0.9	-0.1	0.1	0.5	-0.3	0.6	0.5	0.7	-0.3
Wears glasses or contact lenses	0.3	0.4	2.6	-0.3	-0.1	0.5	0.1	-0.1	-0.5	-0.6	-0.3	1.6	-0.6	0.8	-0.2	-0.4	-0.4	-0.6	-0.1	-0.5	-0.8	-0.7
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.4	1.2	-0.0	1.1	0.2	-0.0	0.6	0.7	0.5	0.0	0.5	0.2	0.1	0.1	0.6	0.2	0.8	0.6	0.7	0.6
Alcohol drinker status: Never	0.3	0.3	1.5	-0.8	0.2	-0.6	0.1	0.3	-0.4	-0.3	-0.9	-1.0	-0.4	0.3	0.1	-1.2	-0.3	-0.5	-0.4	-0.5	-0.4	-0.4
Depression (Nagel 2018)	0.2	0.3	2.0	-0.4	0.7	-0.9	-1.4	0.2	-0.1	-0.6	-0.8	-1.0	0.1	-0.2	0.3	0.1	-0.2	0.3	-0.4	-0.4	-0.1	-0.2
Fed-up feelings	0.2	0.3	0.7	-0.8	-0.7	0.5	0.5	-0.1	-0.6	-0.6	-0.7	-0.3	-0.0	-0.0	-0.2	-0.4	-0.6	-0.3	-0.8	-0.8	-0.5	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.3	0.5	-0.1	0.4	0.6	-0.4	-0.5	-0.2	-1.1	-0.5	-0.5	0.6	-0.2	-0.6	-0.1	-0.8	-0.1	-0.4	-0.2	-0.4
Chronic bronchitis/emphysema (father)	0.2	0.2	2.1	-0.6	-0.0	1.5	0.0	0.4	-0.0	-0.1	-0.0	1.0	0.4	-0.6	-0.1	0.2	-0.3	0.1	-0.3	-0.3	-0.4	-0.2
Number of live births	0.2	0.3	1.5	0.1	0.8	-0.1	-0.7	0.0	0.4	-0.4	-0.4	0.8	0.5	-0.9	-0.8	1.2	-0.6	0.2	-0.6	-0.1	0.1	0.2
Noisy workplace	0.2	0.2	1.1	-0.2	0.0	0.5	0.8	0.7	0.4	0.4	0.6	1.1	0.1	-0.5	0.4	0.4	0.4	0.2	0.2	0.4	0.4	0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.2	0.2	0.1	-0.1	0.4	0.9	0.3	1.1	0.2	0.3	-0.6	0.1	0.8	0.2	0.6	-0.1	0.5	0.7	0.6	0.4
Medication: Seretide 50 evohaler	0.2	0.2	1.2	0.3	-0.7	0.2	0.6	-0.7	-0.6	-0.3	0.1	0.6	-0.5	1.1	-0.4	0.2	0.1	-0.2	0.2	-0.0	-0.5	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.7	0.8	0.4	0.8	1.3	-0.4	-0.0	0.3	0.5	-0.0	-0.1	0.7	-0.1	0.6	0.6	0.0	0.7	0.5	-0.1	-0.2
Chest pain or discomfort	0.2	0.3	2.8	-0.1	0.2	0.3	1.7	0.4	0.1	0.4	0.1	1.5	-0.5	0.2	0.5	-0.1	0.4	-0.1	0.3	0.2	0.1	0.2
Leg pain on walking	0.2	0.3	1.3	-0.5	0.5	-0.7	0.4	1.1	0.4	0.6	0.5	0.6	-0.1	-0.1	1.1	0.1	0.6	0.6	0.4	0.4	-0.0	0.2
Mood swings	0.2	0.3	2.0	-1.4	0.3	-0.7	-0.7	0.9	0.2	0.0	0.2	-0.3	0.6	-0.7	1.0	0.2	0.0	0.7	-0.1	-0.1	-0.3	0.1
Loneliness, isolation	0.2	0.2	1.3	-0.7	-0.0	-0.7	-1.1	-0.1	-0.3	-0.2	-0.2	-1.0	0.2	-0.8	0.4	-0.2	-0.1	-0.0	-0.3	-0.2	-0.3	-0.1
Breast cancer (self-reported)	0.2	0.2	1.2	-0.4	0.1	-1.1	-0.1	-0.1	-0.3	0.2	-0.4	-0.3	-1.0	0.8	0.2	-0.6	0.1	-0.8	-0.0	0.1	-0.3	-0.3
Hearing aid user	0.2	0.2	1.7	-0.5	0.1	0.4	-1.3	-0.5	0.1	-0.2	0.1	-0.5	0.1	-0.3	0.1	-0.4	-0.5	-0.3	-0.6	-0.3	-0.4	0.0
Mother’s age at death	0.2	0.3	1.4	0.4	-0.2	0.1	-0.3	-1.2	-0.4	-0.7	-0.7	-0.8	-0.0	0.1	-0.7	-0.8	-0.5	-0.5	-0.6	-0.4	-0.1	-0.4
High cholesterol (Self-reported)	0.2	0.3	1.4	0.8	-0.6	-0.2	0.7	0.7	-0.4	-0.3	-0.2	1.2	-0.5	0.4	-0.5	0.2	0.2	0.1	0.2	0.3	0.4	-0.5
Average weekly beer plus cider intake	0.2	0.3	1.6	0.7	-0.4	0.2	-0.3	0.6	0.2	0.4	0.4	1.0	0.6	0.1	-0.3	1.3	0.4	0.2	0.3	0.7	0.7	0.0
Age started oral contraceptive pill	0.2	0.3	0.7	-0.5	-0.1	0.5	0.2	-0.8	-0.3	-0.6	-0.6	0.7	-0.8	0.2	-0.5	-0.4	-0.6	-0.7	-0.7	-0.6	-0.2	-0.2
Pain experienced in last month	0.2	0.4	2.3	0.6	-0.9	0.7	-0.9	-0.6	-0.7	-0.4	0.2	-1.5	0.1	0.8	-0.4	-0.4	0.0	-0.1	0.3	0.1	-0.5	-0.6
Depressed Affect (Nagel 2018)	0.1	0.2	1.2	-1.1	-0.2	0.2	-0.4	-0.2	-0.3	-0.6	-0.5	-0.0	-0.2	-0.1	0.1	-0.2	-0.5	-0.2	-0.6	-0.7	-0.7	-0.4
Hypothyroidism (self reported)	0.1	0.3	1.2	1.0	0.3	1.0	-0.2	-0.7	0.1	-0.1	-0.3	1.1	0.0	0.7	-0.6	0.5	0.0	-0.2	0.2	0.3	0.4	-0.2
Tanning	0.1	1.8	6.1	2.2	-0.7	2.2	2.5	-2.3	-0.4	1.0	-0.3	0.8	-0.5	1.0	0.6	-0.4	1.6	-0.3	1.7	1.4	1.1	-0.1
Serious illness, injury or assault to yourself	0.1	0.2	0.8	-0.8	0.4	-0.1	-0.3	0.9	-0.2	-0.6	-0.1	-0.3	-0.3	-0.2	0.1	0.3	-0.1	0.7	0.0	-0.0	-0.3	-0.5
Father’s age at death	0.1	0.2	0.6	0.7	-0.7	0.1	-0.5	-0.2	-0.6	-0.3	-0.3	-0.6	0.2	0.8	-0.6	-0.2	-0.1	-0.4	0.2	-0.2	-0.1	-0.5
Hair/balding pattern: Pattern 4	0.1	0.3	1.1	-0.5	-0.9	-0.0	-0.1	0.3	-0.9	0.3	-0.2	-0.6	-0.2	1.0	1.0	-1.1	0.2	-0.7	-0.1	-0.1	0.0	-0.5
Glaucoma (self-reported)	0.1	0.2	0.6	-0.1	0.4	0.2	0.2	0.8	-0.1	0.1	0.1	0.2	0.5	0.1	0.5	0.1	0.6	0.6	0.6	0.4	0.2	-0.2
Gout (self-reported)	0.1	0.2	1.2	0.7	0.4	0.2	-0.2	-0.6	0.1	-0.2	-0.1	0.8	0.1	0.1	-1.1	0.8	-0.3	-0.2	0.1	0.0	-0.0	-0.1
Number of children fathered	0.1	0.1	0.3	0.5	0.1	0.4	0.3	-0.5	0.1	-0.4	0.0	0.5	-0.1	-0.3	-0.3	0.1	-0.1	0.1	0.0	0.0	0.1	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	1.0	0.0	-0.0	1.0	0.1	0.1	-0.4	-0.1	-0.5	0.1	0.4	0.6	-0.1	-0.3	0.1	0.1	0.1	-0.1	0.1	-0.4
Hair Pigment	0.0	1.1	4.1	0.1	2.0	0.1	-0.8	1.5	1.6	0.7	0.9	0.0	1.3	-1.6	0.2	1.3	-0.1	0.9	0.1	0.3	0.2	1.4

Hub : Genes

ARL3

Models

Trait associations