TWAS hub - AS3MT

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1660	0.0460	3.3e-16	0.160	0.145	0.144	0.148	0.152	5.0e-19	2.6e-17	3.7e-17	1.3e-17	4.5e-18
2	METSIM	Adipose	0.2450	0.0545	0.0e+00	0.279	0.262	0.280	0.274	0.285	7.1e-42	4.5e-39	3.7e-42	5.1e-41	6.1e-43
3	NTR	Blood	0.0313	0.0125	8.6e-06	0.010	0.016	0.012	0.016	0.008	1.9e-04	4.6e-06	8.2e-05	4.4e-06	9.0e-04
4	ROSMAP	Brain Pre-frontal Cortex	0.4353	0.0630	0.0e+00	0.405	0.424	0.446	0.431	0.445	6.9e-56	2.5e-59	2.1e-63	1.5e-60	3.3e-63
5	TCGA	Bladder Urothelial Carcinoma	0.0550	0.0260	8.6e-06	0.086	0.064	0.071	NA	0.071	9.2e-08	4.4e-06	1.3e-06	NA	1.3e-06
6	TCGA	Breast Invasive Carcinoma	0.0477	0.0204	2.6e-10	0.048	0.049	0.053	NA	0.048	3.4e-10	2.6e-10	4.7e-11	NA	4.1e-10
7	TCGA	Colon Adenocarcinoma	0.0940	0.0570	1.3e-03	0.023	0.009	-0.001	NA	0.010	1.6e-02	9.1e-02	3.8e-01	NA	8.1e-02
8	TCGA	Glioblastoma Multiforme	0.1530	0.0830	1.4e-03	0.049	0.103	0.093	NA	0.075	1.3e-02	5.1e-04	9.2e-04	NA	2.7e-03
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0484	0.0222	1.3e-06	0.045	0.064	0.062	NA	0.060	7.5e-06	1.1e-07	1.5e-07	NA	2.9e-07
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0386	0.0238	1.7e-04	0.047	0.035	0.044	NA	0.043	4.9e-06	7.0e-05	8.6e-06	NA	1.2e-05
11	TCGA	Brain Lower Grade Glioma	0.3422	0.0900	0.0e+00	0.378	0.361	0.368	NA	0.384	3.4e-45	9.6e-43	8.1e-44	NA	4.4e-46
12	TCGA	Lung Squamous Cell Carcinoma	0.0435	0.0324	9.2e-03	0.023	0.014	0.021	NA	0.016	9.8e-04	9.3e-03	1.9e-03	NA	4.9e-03
13	TCGA	Pancreatic Adenocarcinoma	0.1460	0.0610	1.0e-06	0.206	0.133	0.179	NA	0.194	4.8e-09	3.2e-06	5.7e-08	NA	1.4e-08
14	TCGA	Pheochromocytoma and Paraganglioma	0.1270	0.0570	4.3e-06	0.144	0.134	0.098	NA	0.107	2.4e-06	5.6e-06	1.0e-04	NA	5.0e-05
15	TCGA	Prostate Adenocarcinoma	0.1596	0.0518	0.0e+00	0.210	0.233	0.234	NA	0.235	1.5e-21	4.9e-24	3.1e-24	NA	2.5e-24
16	TCGA	Soft Tissue Sarcoma	0.2690	0.1030	1.0e-05	0.005	0.061	0.031	NA	0.027	1.5e-01	1.7e-04	5.8e-03	NA	9.3e-03
17	TCGA	Stomach Adenocarcinoma	0.0530	0.0290	5.3e-03	0.017	0.032	0.023	NA	0.027	2.1e-02	2.1e-03	8.2e-03	NA	4.5e-03
18	TCGA	Thyroid Carcinoma	0.2260	0.0880	2.9e-15	0.185	0.162	0.174	NA	0.182	1.1e-17	1.4e-15	1.1e-16	NA	1.8e-17

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Smoking Status	25.9	62.0	91.8	-9.6	-9.1	-7.8	-7.8	-8.0	-7.8	-5.5	-8.1	-7.9	-9.4	-9.2	-5.3	-8.6	-8.7	-8.5	-2.7	-3.8	-9.5
Past tobacco smoking	18.1	33.2	49.9	7.1	6.8	5.6	5.8	5.3	5.6	4.1	5.8	6.0	6.6	6.8	3.8	6.7	6.4	6.2	2.2	3.7	6.7
Ever smoked	16.4	28.8	42.0	-6.5	-6.2	-5.5	-5.4	-5.0	-5.1	-3.8	-5.5	-5.7	-6.0	-6.3	-3.6	-6.0	-6.0	-5.8	-2.7	-3.3	-6.2
Schizophrenia (2018)	14.5	30.1	69.2	4.9	5.4	4.3	4.2	8.3	7.0	2.9	5.9	5.6	7.8	5.6	3.8	4.1	6.4	6.0	0.1	-1.6	7.4
Worrier / anxious feelings	13.2	24.9	53.6	5.2	4.9	4.2	4.1	7.3	5.8	2.5	5.1	5.4	6.8	5.4	3.2	4.1	6.1	5.7	-0.5	-0.5	6.5
Schizophrenia (2014)	13.1	28.9	70.2	4.6	5.2	4.1	4.1	8.4	6.9	2.9	5.7	5.7	7.6	5.4	4.0	3.7	6.3	5.9	-0.3	-1.9	7.2
Bipolar Disorder or Schizophrenia	12.4	30.2	78.4	4.7	5.3	3.9	4.1	8.9	7.2	2.6	5.6	5.6	8.0	5.5	3.5	3.8	6.5	6.1	-0.4	-2.3	7.5
Smoking status: Current	11.9	18.8	31.3	-5.6	-5.1	-4.4	-4.2	-4.8	-4.4	-2.1	-4.1	-4.1	-5.4	-5.3	-2.0	-4.8	-4.9	-4.7	-0.7	-1.8	-5.5
Maternal smoking around birth	10.9	15.8	25.1	-4.9	-4.6	-4.0	-3.8	-4.4	-3.7	-2.3	-3.8	-4.0	-4.9	-4.9	-2.2	-4.5	-4.3	-4.3	-1.5	-1.7	-5.0
Current tobacco smoking	10.7	17.6	28.9	-5.4	-4.9	-4.1	-4.2	-4.5	-4.2	-2.3	-4.0	-4.1	-5.2	-5.1	-2.1	-4.6	-4.8	-4.6	-0.8	-1.8	-5.2
Worry (Nagel 2018)	10.0	21.0	55.4	4.2	4.0	4.6	3.1	7.4	5.6	1.8	4.9	4.7	6.6	4.4	2.7	2.9	5.6	4.8	-1.3	-2.1	6.2
Nervous feelings	9.3	17.4	38.5	4.0	3.9	4.5	3.0	6.2	5.0	1.9	4.5	4.3	5.9	4.2	2.5	3.2	5.0	4.4	-0.2	-1.1	5.6
Smoking status: Previous	8.6	12.9	19.2	-4.3	-4.3	-3.2	-3.8	-2.5	-3.2	-3.4	-3.8	-3.7	-3.6	-4.1	-3.0	-4.4	-3.7	-3.8	-1.8	-3.2	-3.8
Pulse wave peak to peak time	8.2	9.6	16.7	-3.1	-3.0	-2.8	-3.0	-3.3	-3.9	-2.8	-3.6	-3.8	-3.3	-3.0	-3.3	-2.3	-4.1	-3.5	-0.4	-0.8	-3.2
Number of incorrect matches in round	8.0	13.3	19.4	4.2	3.9	4.0	3.5	4.3	3.7	2.4	3.8	4.0	4.4	4.0	2.6	3.5	4.3	4.0	1.6	1.0	4.4
Birth weight of first child	7.9	14.4	26.3	-3.7	-3.7	-4.4	-3.1	-4.5	-5.0	-2.0	-4.3	-4.5	-4.6	-3.7	-2.3	-3.0	-5.1	-4.1	-1.8	-0.8	-4.4
Pulse wave Arterial Stiffness index	7.0	8.2	14.1	2.9	2.8	2.8	2.8	2.9	3.5	2.6	3.3	3.5	3.0	2.8	2.9	2.2	3.8	3.2	0.7	0.8	2.9
Exposure to tobacco smoke outside home	7.0	9.3	14.3	-3.3	-3.3	-3.0	-2.7	-3.6	-3.3	-2.1	-3.2	-3.4	-3.8	-3.5	-2.4	-2.8	-3.7	-3.5	-0.1	-0.4	-3.8
Coronary Artery Disease (CAD)	6.8	8.1	20.9	2.1	2.3	2.6	2.0	4.6	4.0	1.5	3.1	3.2	3.9	2.6	2.3	1.4	3.6	3.1	-0.3	-1.7	3.6
Townsend deprivation index at recruitment	6.1	8.6	11.8	-3.3	-3.3	-3.2	-2.8	-3.1	-3.3	-2.4	-3.0	-3.1	-3.4	-3.1	-2.7	-2.8	-3.3	-3.2	-0.6	-0.8	-3.4
Risk taking	5.9	8.7	13.8	-3.5	-3.7	-3.0	-2.9	-2.7	-2.6	-2.1	-2.8	-2.8	-3.4	-3.6	-1.8	-3.7	-2.7	-3.0	-1.8	-2.1	-3.5
Systolic Blood Pressure	5.6	28.0	127.7	1.6	2.1	3.2	0.6	11.3	6.7	-0.9	4.3	4.8	7.8	3.0	2.0	-0.8	6.1	4.4	-3.7	-9.1	6.7
Financial situation satisfaction	5.5	6.8	10.3	-3.1	-2.7	-3.2	-2.7	-2.4	-3.2	-2.1	-2.8	-2.7	-2.8	-2.7	-2.3	-2.4	-3.2	-2.8	-0.4	-1.1	-2.8
Schizophrenia vs Biploar Disorder	5.3	7.0	13.5	2.0	2.4	2.2	2.0	3.7	3.7	2.0	3.2	2.9	3.4	2.3	3.0	1.6	3.0	2.9	-0.6	-0.9	3.2
Hearing difficulty/problems with background noise	5.3	8.5	13.8	-3.2	-3.0	-2.7	-3.3	-0.8	-2.5	-3.7	-3.4	-3.3	-1.8	-2.9	-3.7	-3.0	-3.1	-2.9	-2.3	-3.4	-2.0
Unable to work because of sickness or disability	5.1	6.6	11.8	-2.8	-2.9	-2.3	-3.0	-0.6	-2.1	-3.1	-2.7	-2.4	-1.7	-2.8	-2.7	-3.2	-2.1	-2.4	-2.4	-3.4	-2.0
Irritability	5.0	8.5	14.4	-3.5	-3.5	-2.8	-3.2	-1.6	-2.4	-2.4	-2.9	-2.8	-2.7	-3.5	-2.0	-3.8	-2.6	-3.0	-2.8	-3.0	-3.0
Prostate Cancer	4.9	6.9	11.0	3.3	2.9	3.1	2.7	2.2	2.9	2.0	2.5	2.8	2.7	3.0	1.8	2.9	2.7	2.8	1.1	1.9	2.8
Systolic blood pressure, automated reading	4.8	13.9	59.8	0.9	1.5	2.1	0.6	7.7	5.1	0.3	3.5	3.7	5.4	2.0	2.4	-0.5	4.2	3.2	-2.1	-6.1	4.6
Pack years adult smoking proportion	4.8	7.3	12.2	-3.5	-3.3	-2.9	-3.1	-1.7	-2.8	-2.3	-2.5	-2.7	-2.6	-3.2	-2.3	-3.1	-2.9	-2.9	-1.3	-2.1	-2.7
Arm predicted mass (right)	4.8	24.5	42.0	-5.0	-4.9	-4.0	-4.0	-6.5	-5.7	-2.9	-5.7	-5.8	-6.3	-5.4	-3.8	-4.1	-6.5	-5.5	-0.1	-0.1	-6.2
Pack years of smoking	4.7	6.9	11.3	-3.4	-3.2	-2.8	-3.0	-1.6	-2.7	-2.2	-2.4	-2.6	-2.5	-3.0	-2.2	-3.0	-2.8	-2.8	-1.2	-2.0	-2.7
Bilateral oophorectomy (both ovaries removed)	4.6	5.3	10.6	2.4	2.3	1.3	2.3	3.3	3.2	1.9	2.0	2.4	3.0	2.3	2.1	1.5	2.7	2.7	-0.1	-0.7	2.8
Pulse wave reflection index	4.6	5.7	12.1	-1.9	-2.4	-0.5	-1.8	-3.5	-2.5	-2.1	-3.1	-2.6	-3.3	-2.6	-2.6	-2.0	-2.4	-2.5	-0.5	0.4	-3.2
Birth weight	4.6	10.0	21.8	-2.7	-2.7	-3.8	-1.9	-4.7	-4.1	-1.4	-4.3	-3.4	-4.1	-2.8	-2.5	-1.8	-4.0	-3.2	-0.0	0.9	-3.9
Medication for pain relief, constipation, heartburn	4.6	7.8	11.8	-2.7	-2.8	-2.4	-2.8	-3.2	-3.4	-2.2	-3.0	-3.1	-3.4	-3.0	-2.3	-2.3	-3.3	-3.2	-2.0	-0.5	-3.3
Leg fat-free mass (right)	4.6	24.8	61.6	-4.5	-4.4	-4.6	-3.2	-7.8	-6.4	-1.5	-5.2	-5.6	-7.0	-5.0	-2.9	-3.2	-6.6	-5.3	0.7	2.2	-6.6
Leg predicted mass (right)	4.6	24.4	61.1	-4.5	-4.3	-4.5	-3.2	-7.8	-6.4	-1.5	-5.1	-5.5	-7.0	-5.0	-2.8	-3.2	-6.5	-5.3	0.7	2.2	-6.5
Leg fat-free mass (left)	4.5	23.8	61.6	-4.4	-4.3	-4.3	-3.1	-7.8	-6.3	-1.4	-4.9	-5.4	-6.9	-4.9	-2.7	-3.1	-6.4	-5.2	1.0	2.4	-6.5
Hip circumference	4.5	19.6	42.5	-4.5	-4.4	-4.3	-3.5	-6.5	-5.2	-1.7	-4.2	-4.7	-6.1	-4.8	-2.4	-3.6	-5.4	-5.0	-0.4	1.0	-5.9
Leg predicted mass (left)	4.4	23.5	60.3	-4.4	-4.3	-4.3	-3.1	-7.8	-6.2	-1.4	-4.9	-5.4	-6.8	-4.9	-2.7	-3.1	-6.4	-5.2	0.9	2.3	-6.4
Mouth/teeth dental problems	4.4	6.7	10.0	3.0	3.2	2.7	2.6	2.2	2.7	1.9	2.7	2.5	3.0	3.0	1.9	3.1	2.6	2.6	1.3	1.5	3.1
Weight	4.4	21.6	47.2	-4.7	-4.4	-4.4	-3.4	-6.9	-5.6	-1.8	-4.6	-5.2	-6.3	-5.0	-2.7	-3.6	-6.0	-5.2	0.3	1.1	-6.0
Basal metabolic rate	4.4	24.2	52.0	-4.7	-4.5	-4.2	-3.5	-7.2	-6.1	-2.2	-5.4	-5.7	-6.6	-5.1	-3.4	-3.5	-6.6	-5.4	0.5	1.2	-6.3
Alcohol intake versus 10 years previously	4.3	6.4	10.4	-3.2	-3.1	-1.8	-2.6	-2.5	-2.0	-1.8	-2.6	-2.5	-3.0	-3.2	-1.7	-3.2	-2.6	-2.7	-1.2	-1.5	-3.1
Arm fat-free mass (right)	4.3	22.2	39.9	-4.7	-4.5	-3.8	-3.6	-6.3	-5.5	-2.6	-5.4	-5.6	-6.1	-5.1	-3.5	-3.8	-6.3	-5.3	0.1	0.1	-5.9
Whole body fat-free mass	4.3	24.6	52.4	-4.7	-4.5	-4.1	-3.5	-7.2	-6.1	-2.4	-5.6	-5.8	-6.6	-5.1	-3.6	-3.5	-6.7	-5.4	0.6	1.2	-6.3
Arm predicted mass (left)	4.3	21.9	41.2	-4.6	-4.4	-3.8	-3.6	-6.4	-5.6	-2.6	-5.3	-5.6	-6.0	-5.0	-3.5	-3.6	-6.3	-5.3	0.2	0.5	-5.8
Hand grip strength (left)	4.2	11.0	18.5	-3.5	-3.3	-1.4	-2.8	-4.1	-3.5	-2.7	-4.1	-4.0	-3.9	-3.6	-2.9	-2.9	-4.3	-4.0	0.4	-0.9	-3.9
Whole body water mass	4.2	24.0	51.4	-4.6	-4.4	-4.0	-3.4	-7.2	-6.0	-2.3	-5.6	-5.8	-6.5	-5.0	-3.5	-3.4	-6.6	-5.4	0.6	1.2	-6.2
Arm fat-free mass (left)	4.2	21.1	40.3	-4.5	-4.3	-3.8	-3.4	-6.3	-5.5	-2.4	-5.3	-5.5	-6.0	-4.9	-3.3	-3.5	-6.2	-5.1	0.2	0.5	-5.8
Trunk fat-free mass	4.1	23.3	42.9	-4.7	-4.5	-3.8	-3.6	-6.5	-5.7	-2.9	-5.8	-5.8	-6.1	-5.0	-3.9	-3.6	-6.5	-5.3	0.3	0.2	-5.9
Mouth/teeth dental problems: Dentures	4.1	6.9	9.1	-3.0	-3.0	-1.8	-2.7	-2.6	-2.9	-2.3	-3.0	-2.8	-3.0	-2.9	-2.5	-2.7	-3.0	-2.9	-0.6	-1.0	-3.0
Trunk predicted mass	4.1	23.3	43.0	-4.7	-4.5	-3.9	-3.6	-6.5	-5.7	-2.9	-5.8	-5.8	-6.2	-5.0	-3.9	-3.6	-6.6	-5.3	0.3	0.3	-5.9
Suffer from ‘nerves’	4.1	6.5	19.1	2.1	2.2	2.1	1.5	4.4	3.3	0.7	2.6	2.6	3.9	2.5	1.2	1.5	3.1	2.7	-0.7	-1.5	3.6
Commuting to job workplace: Car/motor vehicle	4.1	4.7	6.2	-2.0	-2.2	-2.2	-2.2	-2.3	-2.5	-1.8	-2.5	-2.3	-2.4	-2.4	-1.7	-2.0	-2.3	-2.3	-1.9	-0.9	-2.5
Relative age of first facial hair	4.0	8.3	12.7	-3.4	-3.5	-1.8	-3.6	-2.4	-3.2	-2.9	-2.5	-2.7	-3.1	-3.4	-3.0	-3.3	-2.6	-3.2	-0.7	-1.6	-3.2
Average weekly fortified wine intake	3.8	4.5	7.3	2.6	2.4	1.9	2.4	1.1	1.7	1.9	2.2	2.1	1.7	2.5	1.6	2.7	2.1	2.2	2.0	2.4	1.9
Peak expiratory flow (PEF)	3.8	8.9	15.7	-3.3	-2.9	-2.3	-2.7	-3.2	-3.1	-2.1	-3.5	-3.7	-3.4	-3.4	-2.3	-3.0	-4.0	-3.5	-0.3	-1.4	-3.4
Neuroticism (Nagel 2018)	3.5	8.2	24.5	2.3	2.2	2.8	1.6	5.0	3.6	1.2	3.2	3.0	4.1	2.5	1.9	1.3	3.5	3.0	-1.0	-1.8	3.8
Heart disease (mother)	3.5	4.3	7.8	1.6	1.9	1.9	1.7	2.8	2.6	1.6	2.5	2.5	2.6	2.1	1.8	1.5	2.6	2.4	0.6	-0.0	2.5
Medication: Paracetamol	3.5	5.4	9.7	2.1	2.0	2.7	1.9	3.1	3.1	1.0	2.3	2.7	2.9	2.4	1.1	1.7	2.9	2.6	1.8	-0.0	2.8
Diverticular disease/diverticulitis (self-reported)	3.4	4.1	6.9	2.0	2.2	2.6	1.9	1.3	2.2	2.0	2.1	2.4	1.8	2.2	1.9	2.3	2.1	2.2	0.9	1.7	1.9
Alcohol usually taken with meals	3.4	5.5	9.4	3.1	2.9	2.5	2.4	2.3	2.5	1.4	2.2	1.9	2.9	2.9	1.4	2.9	2.2	2.4	-0.2	1.2	2.9
Medication: Paracetamol	3.4	5.7	10.4	2.2	2.0	2.6	2.1	3.0	3.2	1.1	2.5	2.8	2.8	2.4	1.2	1.7	3.1	2.7	1.9	0.3	2.8
Migraine (self-reported)	3.3	4.1	13.9	-1.0	-1.4	-0.3	-1.1	-3.7	-2.3	-1.7	-2.6	-2.3	-2.8	-1.4	-2.5	-0.4	-2.3	-2.2	0.2	1.9	-2.5
Deep venous thrombosis (DVT) (self-reported)	3.3	4.3	6.7	2.2	2.2	1.9	2.2	1.8	2.2	1.6	2.4	2.3	2.1	2.3	1.6	2.1	2.6	2.3	1.3	1.5	2.2
Leg fat mass (left)	3.3	12.7	29.8	-3.8	-3.5	-3.6	-2.6	-5.5	-4.0	-0.9	-3.1	-3.8	-5.0	-4.0	-1.3	-3.0	-4.5	-4.0	-0.1	1.0	-4.8
Blood clot in the leg (DVT)	3.2	4.2	6.1	2.2	2.2	1.9	2.2	1.6	2.2	1.6	2.4	2.2	2.0	2.3	1.7	2.1	2.5	2.2	1.4	1.6	2.1
Blood White Count	3.1	22.7	41.9	-6.3	-5.8	-4.8	-5.4	-1.8	-3.9	-4.6	-4.1	-4.5	-3.8	-5.6	-3.1	-6.5	-4.4	-4.9	-2.9	-6.3	-4.3
Neuroticism	3.1	7.6	26.6	2.1	1.8	2.7	0.9	5.2	3.5	-0.0	2.6	2.6	4.1	2.1	0.8	0.8	3.5	2.6	-2.4	-2.7	3.7
Leg fat mass (right)	3.1	12.2	29.2	-3.7	-3.4	-3.3	-2.6	-5.4	-4.0	-1.0	-3.0	-3.8	-4.9	-3.9	-1.4	-2.9	-4.4	-4.0	0.0	1.1	-4.7
Had major operations	3.1	3.6	5.3	-2.1	-2.2	-0.6	-2.2	-2.0	-1.7	-1.9	-1.9	-1.9	-2.1	-2.3	-2.1	-2.1	-1.9	-2.3	-0.5	-0.8	-2.2
Mineral and other dietary supplements	3.1	4.2	7.2	2.2	2.3	1.3	1.9	2.4	2.0	1.2	2.2	2.2	2.7	2.5	1.2	2.0	2.5	2.2	0.8	0.5	2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.0	3.6	5.1	-2.1	-2.2	-2.2	-2.3	-1.1	-2.1	-1.7	-1.8	-1.9	-1.8	-2.2	-1.6	-2.2	-2.1	-2.1	-0.7	-1.6	-1.9
Mouth/teeth dental problems: Bleeding gums	2.9	3.8	6.4	-2.1	-2.1	-2.5	-1.8	-1.9	-2.1	-0.9	-2.0	-2.0	-2.2	-2.1	-1.0	-2.1	-2.1	-1.9	-1.8	-1.1	-2.2
Hand grip strength (right)	2.8	7.7	14.1	-3.1	-2.7	-1.0	-2.3	-3.8	-2.8	-1.9	-3.2	-3.3	-3.5	-3.1	-2.1	-2.5	-3.6	-3.4	0.7	-0.5	-3.4
Medication: Ramipril	2.8	3.6	12.5	1.3	1.2	2.0	1.1	3.5	2.5	0.5	1.8	2.2	2.7	1.6	1.1	0.5	2.6	2.0	0.4	-1.7	2.4
Happiness	2.8	3.4	5.1	2.0	2.0	2.2	2.0	1.5	2.3	1.5	1.8	1.9	1.9	2.0	1.2	2.0	1.9	2.0	1.1	1.4	1.9
Waist circumference	2.7	9.7	21.3	-3.4	-3.1	-2.7	-2.4	-4.6	-3.6	-1.1	-2.8	-3.4	-4.3	-3.5	-1.5	-2.7	-3.9	-3.5	0.5	0.7	-4.2
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.7	12.7	-2.7	-2.1	-2.0	-2.0	-2.6	-3.0	-1.6	-2.9	-3.0	-2.5	-2.5	-1.9	-1.9	-3.6	-2.7	0.6	-1.0	-2.5
Qualifications: nursing, teaching	2.7	4.3	11.1	2.4	2.3	3.3	2.2	1.4	1.9	1.6	2.0	1.8	2.0	2.3	1.4	2.5	1.7	2.0	1.7	1.7	2.1
Bipolar Disorder (2018)	2.6	4.1	14.4	1.5	1.6	0.9	1.3	3.8	2.7	0.5	1.6	2.0	3.1	1.8	0.8	0.9	2.5	2.3	-0.8	-1.7	2.8
Body Mass Index (BMI) (2010)	2.6	3.6	14.1	-1.6	-1.5	-1.0	-0.9	-3.8	-2.1	0.4	-1.3	-1.8	-3.0	-1.9	-0.1	-0.8	-2.5	-1.9	0.6	2.0	-2.8
HbA1C	2.6	2.9	4.1	1.6	1.8	1.8	1.6	1.9	2.0	1.6	1.8	1.7	2.0	1.7	1.7	1.4	1.9	1.9	0.9	0.4	2.0
Eye problems/disorders: Diabetes related eye disease	2.6	2.8	4.0	-1.8	-1.9	-1.6	-1.4	-1.9	-2.0	-1.2	-1.7	-1.9	-2.0	-1.9	-1.3	-1.8	-1.8	-2.0	-0.2	-0.7	-2.0
Qualifications: College or University degree	2.6	8.3	13.5	3.5	3.4	3.5	2.8	2.8	2.7	1.7	2.9	2.5	3.6	3.6	1.6	3.6	2.8	3.0	0.6	1.5	3.7
Major Depression (MDD)	2.5	3.1	12.5	0.5	0.6	1.0	0.6	3.5	2.4	0.5	1.7	1.9	2.5	1.0	1.3	-0.2	2.0	1.7	-0.1	-2.6	2.2
Ulcerative Colitis	2.5	3.7	6.2	-2.0	-2.2	-1.7	-2.0	-0.3	-1.6	-2.5	-2.3	-2.0	-1.1	-1.9	-2.3	-2.2	-1.7	-2.0	-1.6	-2.5	-1.3
Sensitivity / hurt feelings	2.5	4.2	9.3	2.0	1.8	2.6	1.4	3.0	2.3	1.0	2.3	2.1	2.8	2.0	1.4	1.5	2.3	2.0	1.1	-0.6	2.6
Standing height	2.5	25.2	46.9	-5.3	-4.9	-2.2	-4.7	-4.7	-5.9	-4.9	-6.5	-6.4	-4.9	-5.0	-5.8	-4.1	-6.8	-5.7	0.3	-2.6	-4.9
Whole body fat mass	2.5	10.5	28.4	-3.4	-3.0	-3.2	-2.1	-5.3	-3.8	-0.2	-2.5	-3.3	-4.7	-3.5	-0.7	-2.5	-4.1	-3.6	0.4	1.5	-4.5
Reaction Time	2.4	4.5	7.5	2.1	2.1	1.3	1.7	2.6	2.2	2.1	2.7	2.6	2.6	2.1	2.3	1.5	2.7	2.4	-0.2	-0.1	2.5
Rheumatoid Arthritis	2.4	3.3	4.9	-2.0	-2.0	-1.7	-1.8	-1.3	-1.5	-1.6	-1.9	-2.1	-1.7	-2.1	-1.6	-2.2	-1.9	-2.0	-1.7	-1.6	-1.8
Trunk fat mass	2.4	10.1	28.6	-3.3	-3.0	-2.9	-2.0	-5.3	-3.9	-0.1	-2.4	-3.2	-4.7	-3.4	-0.7	-2.3	-4.0	-3.5	0.7	1.7	-4.4
Number of live births	2.4	3.4	6.8	1.7	1.7	2.6	1.4	2.3	2.2	1.1	2.1	2.0	2.3	1.9	1.5	1.3	2.2	1.9	0.7	-0.2	2.2
Pulse rate	2.4	4.1	7.6	1.7	2.0	0.9	1.6	2.3	2.3	1.8	2.8	2.7	2.3	2.1	2.2	1.8	2.6	2.2	0.6	0.8	2.3
Supplements: Calcium	2.4	2.7	4.3	-1.8	-1.8	-1.4	-1.9	-1.1	-1.5	-0.9	-1.5	-1.7	-1.5	-2.0	-0.6	-1.9	-2.1	-1.8	-1.9	-1.7	-1.6
BMI	2.3	13.6	51.4	-2.7	-2.6	-3.7	-1.5	-7.2	-4.4	0.7	-2.6	-3.4	-5.8	-3.5	-0.1	-1.7	-4.4	-3.6	0.5	3.9	-5.3
Supplements: Zinc	2.3	2.5	4.3	-1.8	-1.9	-1.0	-1.4	-1.7	-1.7	-1.0	-1.7	-1.8	-1.9	-1.9	-1.1	-1.8	-2.1	-1.7	-0.2	-0.9	-1.9
Age when periods started (menarche)	2.2	5.4	12.0	-2.3	-2.6	-2.6	-1.7	-3.5	-2.6	-0.8	-1.9	-2.2	-3.4	-2.7	-1.1	-2.1	-2.3	-2.4	0.1	0.7	-3.3
Neuroticism score	2.2	4.5	14.7	1.6	1.5	1.8	0.9	3.8	2.9	0.4	2.1	2.3	3.1	1.7	1.0	0.8	2.7	2.1	-1.4	-1.7	2.8
Exposure to tobacco smoke at home	2.2	2.4	8.0	-1.6	-1.6	-2.8	-1.2	-2.0	-2.0	-0.5	-0.8	-1.3	-2.1	-1.7	-0.4	-1.1	-1.6	-1.5	0.1	0.7	-2.1
Arm fat mass (left)	2.2	9.1	27.2	-3.0	-2.7	-3.3	-1.8	-5.2	-3.5	0.2	-2.2	-2.9	-4.5	-3.1	-0.4	-2.1	-3.7	-3.2	0.5	1.9	-4.2
Bipolar Disorder (2011)	2.1	2.0	7.3	1.0	0.8	0.8	0.7	2.7	2.1	0.1	1.0	1.3	2.1	1.1	0.4	0.5	1.8	1.6	-1.0	-1.6	1.9
Vitamin and mineral supplements	2.1	2.8	5.1	1.8	1.9	0.8	1.3	2.2	1.4	1.1	1.9	1.9	2.2	2.1	1.2	1.8	1.9	1.9	0.2	0.5	2.2
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.7	5.4	2.1	1.9	2.3	1.7	1.1	2.1	1.2	1.6	1.5	1.6	1.7	1.0	1.8	1.6	1.7	0.6	1.3	1.7
Worry too long after embarrassment	2.1	3.5	8.8	1.8	1.6	2.1	1.2	3.0	2.3	1.0	2.3	1.9	2.6	1.6	1.4	1.1	2.1	1.9	0.1	-0.9	2.4
Allergy or Eczema	2.0	5.3	10.8	3.3	2.5	1.6	2.5	1.0	2.1	2.1	2.3	2.6	1.9	2.8	1.8	3.0	2.6	2.5	-0.4	2.8	2.1
Impedance of leg (right)	2.0	9.5	39.0	1.3	1.5	3.5	0.3	6.2	3.8	-1.3	2.2	2.4	5.0	2.2	-0.0	0.5	3.3	2.3	-1.2	-4.7	4.4
Body mass index (BMI)	2.0	8.4	27.1	-2.6	-2.4	-3.5	-1.5	-5.2	-3.2	0.4	-1.9	-2.5	-4.5	-3.0	-0.2	-1.9	-3.2	-2.9	0.2	2.5	-4.2
Arm fat mass (right)	2.0	8.4	25.3	-2.8	-2.5	-3.1	-1.7	-5.0	-3.5	0.1	-2.1	-2.9	-4.3	-3.0	-0.5	-1.9	-3.6	-3.1	0.4	1.9	-4.0
Average weekly red wine intake	2.0	2.9	6.2	1.7	1.7	0.8	1.9	1.7	1.7	2.3	2.1	1.8	1.8	1.6	2.5	1.4	1.7	1.9	0.1	0.4	1.7
Commuting to job workplace: Walk	2.0	2.1	7.5	0.9	1.0	0.5	1.0	2.7	2.0	0.9	1.3	1.4	2.1	1.2	1.4	0.4	1.4	1.6	-1.1	-1.6	1.9
Illnesses of father: None of the above (group 1)	2.0	2.5	6.4	-0.7	-1.0	-0.8	-1.0	-2.5	-2.5	-0.9	-1.8	-2.0	-1.9	-1.1	-1.5	0.0	-2.3	-1.7	-0.8	1.6	-1.7
Medication: Lisinopril	2.0	2.6	6.9	1.2	1.5	1.0	1.3	2.6	1.8	1.0	1.6	1.8	2.2	1.6	1.5	1.0	1.6	1.8	0.9	-1.0	2.1
Diastolic blood pressure, automated reading	2.0	6.2	51.4	-2.3	-1.7	-1.0	-2.0	3.5	0.8	-1.9	-0.8	-0.6	1.2	-1.7	-0.2	-3.7	-0.1	-0.6	-3.2	-7.2	0.5
Neuroticism (2016)	1.9	2.7	7.0	1.4	1.3	0.6	1.2	2.6	2.2	1.3	1.8	1.9	2.1	1.3	1.8	0.7	2.0	1.9	-0.7	-1.1	1.9
Height	1.9	37.2	76.6	-6.4	-5.8	-1.8	-5.4	-6.2	-7.3	-5.4	-8.0	-7.9	-6.2	-6.1	-6.6	-4.8	-8.8	-6.9	1.6	-2.6	-6.2
Ever used hormone-replacement therapy (HRT)	1.9	2.4	4.8	1.6	1.4	1.6	1.3	1.8	1.8	0.8	1.6	2.0	1.8	1.5	1.2	1.1	2.2	1.8	0.8	0.0	1.7
Ever had hysterectomy (womb removed)	1.9	2.2	4.3	2.1	1.6	1.8	1.6	1.5	1.6	0.8	0.9	1.3	1.7	1.8	0.6	1.7	1.5	1.6	0.2	0.8	1.7
High blood pressure	1.9	5.3	41.0	-2.1	-1.6	-0.9	-1.9	3.8	1.0	-1.5	-0.2	0.1	1.5	-1.1	0.1	-3.0	0.4	-0.1	-3.6	-6.4	0.8
Chronic bronchitis/emphysema (father)	1.9	2.2	3.7	1.1	1.4	1.3	1.4	1.5	1.8	1.4	1.8	1.8	1.5	1.3	1.5	1.1	1.7	1.6	1.9	0.8	1.5
Number of full brothers	1.9	2.4	5.6	-2.1	-1.8	-2.4	-1.6	-0.4	-1.1	-1.1	-1.4	-1.1	-1.2	-1.9	-1.0	-2.2	-1.2	-1.4	-0.3	-2.1	-1.4
Hypertension (Self-reported)	1.9	5.2	39.2	-2.1	-1.6	-1.1	-1.9	3.7	0.9	-1.5	-0.2	0.0	1.4	-1.2	0.1	-2.9	0.3	-0.1	-3.7	-6.3	0.7
Illnesses of father: Heart disease	1.9	2.6	4.6	1.0	1.5	1.5	1.5	2.0	2.1	1.4	1.8	1.7	1.9	1.5	2.1	0.7	1.8	1.7	0.0	-1.1	1.8
Financial difficulties in last 2 years	1.8	2.5	4.0	-2.0	-1.7	-1.3	-2.0	-0.6	-1.4	-1.7	-1.8	-1.5	-1.2	-1.7	-1.5	-1.7	-1.9	-1.6	-0.4	-1.8	-1.3
Allergy	1.8	4.1	6.6	-2.5	-2.1	-2.0	-1.9	-0.8	-1.8	-1.8	-2.3	-2.6	-1.5	-2.3	-1.7	-2.5	-2.5	-2.2	-0.7	-2.5	-1.7
Knee pain experienced in last month	1.8	2.8	6.0	-1.9	-2.0	-1.8	-1.2	-2.3	-1.5	-0.3	-1.5	-1.5	-2.5	-2.1	-0.6	-1.8	-1.7	-1.6	-0.4	0.1	-2.4
Vascular/heart problems diagnosed by doctor	1.8	4.9	39.1	1.7	1.2	0.7	1.4	-4.0	-1.5	0.8	-0.3	-0.5	-1.7	0.8	-0.9	2.7	-0.8	-0.3	3.0	6.3	-1.1
Breast Cancer	1.7	4.1	6.7	2.2	2.4	0.7	2.5	1.3	1.6	2.4	2.0	2.0	1.8	2.3	2.2	2.6	1.7	2.3	1.0	1.9	2.0
Cardiovascular Disease	1.7	5.6	45.2	-1.6	-1.2	-1.3	-1.7	4.3	1.0	-1.5	0.1	0.2	1.9	-0.9	0.2	-2.7	0.6	0.1	-3.5	-6.7	1.2
Heart attack	1.7	2.2	6.3	0.5	0.9	0.9	0.9	2.0	2.1	1.7	1.8	1.7	1.7	0.8	2.5	-0.1	1.6	1.4	0.1	-1.7	1.4
Breastfed as a baby	1.7	2.2	7.2	1.5	1.4	1.1	0.9	2.7	1.8	-0.5	0.8	1.0	2.4	1.7	-0.4	1.1	1.6	1.3	-0.3	-1.0	2.3
Mean time to correctly identify matches	1.7	3.3	6.2	1.6	1.6	1.4	1.5	2.5	2.0	1.7	2.0	2.0	2.3	1.8	2.0	1.1	2.1	2.1	-0.0	-0.5	2.2
Eye problems/disorders: Glaucoma	1.7	2.0	4.4	1.1	1.4	2.1	1.2	1.6	2.0	0.9	1.6	1.4	1.7	1.5	0.9	1.1	1.5	1.2	1.0	0.3	1.7
Hearing difficulty/problems: Yes	1.6	2.5	4.7	-1.9	-1.8	-1.1	-1.9	-0.2	-1.2	-1.9	-1.8	-1.5	-1.0	-1.6	-1.7	-1.7	-1.5	-1.4	-1.6	-2.2	-1.1
High blood pressure (mother)	1.6	2.2	12.4	-0.3	-0.1	0.2	-0.8	3.0	1.1	-0.9	0.6	0.7	1.5	-0.1	0.2	-1.3	1.2	0.6	-2.8	-3.5	1.1
Impedance of leg (left)	1.6	7.9	34.4	0.9	1.1	2.8	0.1	5.9	3.4	-1.3	1.8	2.0	4.5	1.7	0.1	0.0	2.8	1.9	-1.8	-5.0	3.9
Had menopause	1.6	2.1	4.7	1.3	1.1	1.6	0.8	2.2	2.0	0.0	1.3	1.5	2.0	1.4	0.4	0.8	2.1	1.5	-0.8	-0.6	1.9
Medication: Lansoprazole	1.6	1.9	3.1	1.3	1.4	0.3	1.5	1.7	1.3	1.4	1.3	1.7	1.5	1.5	1.7	1.2	1.3	1.8	1.2	0.3	1.5
Long-standing illness, disability or infirmity	1.6	2.4	5.0	-1.6	-1.8	-1.3	-1.6	-0.1	-0.9	-2.0	-1.5	-1.7	-0.8	-1.5	-1.8	-2.1	-1.2	-1.5	-1.8	-2.2	-1.0
Wears glasses or contact lenses	1.6	1.8	3.8	1.5	1.4	1.2	1.3	2.0	1.7	0.5	1.1	1.2	1.8	1.5	0.8	1.3	1.4	1.6	0.1	-0.0	1.7
Impedance of whole body	1.6	8.2	29.8	1.6	1.8	2.8	0.9	5.5	3.3	0.0	2.8	2.7	4.5	2.5	1.1	1.1	3.4	2.6	-1.1	-3.3	4.1
Verbal and Numeric Reasoning (VNR)	1.5	3.6	7.1	-1.5	-1.5	-2.7	-1.7	-1.6	-2.3	-2.0	-2.4	-2.5	-1.5	-1.4	-2.3	-0.9	-2.5	-2.0	-1.6	-0.5	-1.5
Blood Platelet Count	1.5	16.9	27.0	-5.2	-5.1	-3.3	-4.5	-4.0	-4.5	-3.3	-3.7	-4.0	-4.7	-4.8	-2.9	-4.7	-4.2	-4.5	0.3	-2.5	-4.8
Chronotype (morning person)	1.5	3.4	8.6	-1.3	-1.5	-2.2	-1.5	-1.2	-1.8	-1.9	-2.9	-2.2	-1.5	-1.5	-2.2	-1.4	-2.1	-1.7	-2.5	-1.2	-1.6
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	4.1	-1.5	-1.7	-1.1	-1.7	0.0	-0.8	-1.6	-1.3	-1.1	-0.9	-1.6	-1.2	-1.9	-1.0	-1.2	-1.5	-2.0	-1.1
Prospective memory result	1.5	1.9	3.7	1.2	1.3	1.1	1.6	0.8	0.8	1.9	1.5	1.4	1.1	1.5	1.9	1.3	1.0	1.3	1.8	1.0	1.2
Medication: Ventolin 100micrograms inhaler	1.5	1.9	3.9	1.2	1.2	1.5	1.1	0.3	0.9	1.3	2.0	1.7	0.9	1.3	1.5	1.4	1.6	1.3	1.8	1.7	1.0
Back pain experienced in last month	1.5	2.2	5.4	-1.9	-1.7	-1.5	-1.5	-0.2	-0.8	-1.0	-1.5	-1.5	-1.1	-1.8	-0.7	-2.2	-1.5	-1.3	-1.6	-2.3	-1.3
Breast cancer (self-reported)	1.5	1.8	3.5	-1.4	-1.4	-1.5	-1.4	-0.7	-1.2	-1.3	-1.6	-1.4	-1.2	-1.2	-1.1	-1.4	-1.4	-1.3	-1.9	-1.4	-1.2
Lung FEV1/FVC ratio	1.4	7.0	12.7	-3.1	-2.5	-3.4	-2.2	-3.6	-2.4	-1.6	-2.6	-2.5	-3.5	-2.9	-2.1	-2.5	-2.9	-2.9	0.8	0.2	-3.4
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	8.8	-2.4	-2.0	-1.1	-2.2	-1.0	-1.5	-2.2	-2.7	-2.7	-1.6	-2.4	-2.2	-2.7	-2.6	-2.4	-0.8	-3.0	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	7.9	0.6	0.5	1.3	-0.0	2.8	1.5	-0.1	1.1	1.6	1.9	0.8	0.5	-0.1	1.8	1.3	-0.8	-2.1	1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	5.4	-1.4	-1.4	-0.8	-1.9	-0.0	-1.2	-2.3	-1.1	-0.8	-0.6	-1.1	-2.0	-1.4	-0.5	-1.1	0.2	-1.7	-0.8
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	3.5	-1.6	-1.6	-1.4	-1.3	-1.1	-1.1	-0.5	-0.9	-1.2	-1.5	-1.7	-0.3	-1.9	-1.2	-1.3	-0.6	-1.0	-1.6
Medication: Blood pressure	1.4	2.7	20.9	-1.7	-1.3	-0.6	-1.5	2.2	0.5	-0.8	-0.0	0.0	0.7	-1.1	0.5	-2.4	0.1	-0.3	-2.4	-4.6	0.3
Heart attack/myocardial infarction (self-reported)	1.4	1.8	6.0	0.2	0.7	0.6	0.7	1.8	1.8	1.6	1.7	1.5	1.5	0.6	2.4	-0.2	1.4	1.2	-0.0	-1.8	1.2
Crohns Disease (2012)	1.3	2.0	4.8	-2.2	-1.8	-0.3	-1.5	-1.1	-1.1	-0.9	-1.3	-1.5	-1.4	-1.8	-0.6	-1.8	-1.7	-1.7	-0.8	-1.4	-1.5
Heel T-Score	1.3	10.1	31.8	4.0	3.5	4.3	3.7	-0.2	1.8	1.8	1.8	1.7	1.9	3.6	0.2	4.9	2.0	2.5	4.5	5.6	2.4
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.1	6.2	2.0	1.9	2.5	1.8	0.7	1.5	0.9	1.5	1.3	1.6	2.1	0.4	2.3	1.5	1.4	2.4	2.1	1.8
Forced vital capacity (FVC)	1.3	5.2	13.5	-2.5	-2.1	-1.0	-2.4	-0.7	-1.5	-2.3	-2.9	-2.8	-1.4	-2.5	-2.2	-2.8	-2.8	-2.4	-1.1	-3.7	-1.6
Qualifications: None of the above	1.3	2.8	5.7	-2.2	-2.0	-1.4	-1.8	-0.9	-1.2	-1.0	-1.7	-1.6	-1.6	-2.1	-0.9	-2.4	-1.7	-1.7	-1.2	-1.8	-1.8
Impedance of arm (right)	1.3	6.2	15.4	2.0	2.2	2.4	1.4	3.9	2.6	1.2	2.8	2.6	3.7	2.6	1.6	1.8	3.0	2.6	-0.2	-1.3	3.5
Impedance of arm (left)	1.3	6.1	16.2	1.8	2.0	2.2	1.4	4.0	2.7	1.2	2.9	2.7	3.7	2.5	1.7	1.6	3.1	2.6	-0.3	-1.5	3.4
Tense / ‘highly strung’	1.3	2.1	14.5	-0.6	-0.5	-0.3	-0.6	2.6	1.4	-0.4	0.2	0.1	1.3	-0.5	0.5	-1.5	0.5	0.2	-2.8	-3.8	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	3.5	0.7	1.1	0.2	1.6	0.9	1.8	1.7	1.2	1.5	1.0	1.1	1.9	0.7	1.3	1.4	1.3	0.2	1.0
Ever taken oral contraceptive pill	1.3	1.5	6.8	-0.5	-0.7	0.5	-0.5	-2.6	-1.1	-0.4	-0.7	-0.9	-1.8	-0.9	-0.8	-0.3	-1.0	-1.2	1.5	1.8	-1.6
LDL Cholesterol	1.2	1.9	3.1	1.3	1.5	1.3	1.5	1.1	1.8	1.4	1.4	1.6	1.3	1.5	1.4	1.4	1.6	1.5	0.6	1.0	1.4
Lupus	1.2	1.9	3.9	-1.2	-1.2	-1.0	-1.3	-1.6	-1.8	-1.3	-2.0	-1.6	-1.4	-1.1	-1.6	-0.8	-1.9	-1.5	-0.1	-0.4	-1.3
Medication: Atenolol	1.2	1.5	7.2	-1.4	-1.2	-1.2	-1.1	0.6	-0.6	-0.7	-0.6	-1.1	-0.2	-1.2	-0.3	-1.7	-0.8	-0.9	-2.1	-2.7	-0.4
Overall health rating	1.2	2.6	4.1	-1.9	-1.8	-1.9	-1.6	-0.7	-1.4	-1.2	-1.6	-1.6	-1.5	-1.7	-1.0	-2.0	-1.6	-1.5	-2.0	-1.8	-1.5
Miserableness	1.2	2.1	4.1	-1.4	-1.5	-1.1	-1.6	-0.8	-1.5	-1.8	-1.8	-1.6	-1.2	-1.4	-2.0	-1.4	-1.5	-1.5	-1.0	-1.2	-1.2
Commuting to job workplace: Public transport	1.2	1.4	3.9	1.2	1.1	2.0	1.1	1.1	1.1	0.5	1.4	1.1	1.4	1.4	0.4	1.4	1.3	1.1	0.8	0.8	1.4
Medication: Atorvastatin	1.2	1.4	8.0	-0.9	-1.1	-0.8	-1.1	1.1	0.1	-1.3	-0.7	-0.8	0.2	-0.8	-0.8	-1.6	-0.5	-0.6	-2.4	-2.8	-0.1
Leg fat percentage (left)	1.2	4.2	10.6	-2.3	-2.1	-2.3	-1.4	-3.2	-1.9	-0.1	-1.3	-2.0	-3.0	-2.5	-0.0	-2.0	-2.4	-2.3	-0.4	0.6	-2.9
Trunk fat percentage	1.1	4.3	13.5	-2.2	-2.0	-2.0	-1.2	-3.7	-2.5	0.6	-0.9	-1.8	-3.1	-2.2	0.3	-1.6	-2.4	-2.2	0.4	1.5	-2.9
Sitting height	1.1	8.1	17.1	-3.1	-2.6	-1.5	-2.6	-0.7	-3.0	-3.1	-3.8	-3.8	-1.5	-2.8	-3.1	-3.0	-3.8	-2.8	-1.2	-4.1	-1.8
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.8	10.6	0.0	0.0	0.4	-0.5	2.4	1.3	-0.7	0.3	0.4	1.6	0.1	0.1	-0.6	0.8	0.5	-2.8	-3.3	1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	8.7	1.9	1.6	2.5	1.6	0.3	0.9	0.4	1.1	1.0	1.2	1.8	-0.3	2.1	1.3	1.2	2.9	2.5	1.4
Arm fat percentage (right)	1.1	4.5	16.3	-1.9	-1.6	-2.7	-0.9	-4.0	-2.4	1.1	-0.8	-1.7	-3.2	-2.0	0.6	-1.1	-2.4	-2.0	0.4	2.2	-2.9
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	3.4	-1.6	-1.4	-1.9	-1.1	-1.6	-1.4	-0.8	-1.3	-1.4	-1.5	-1.3	-0.9	-1.1	-1.6	-1.5	-0.1	-0.4	-1.5
Length of working week for main job	1.1	1.3	2.4	-1.3	-1.3	-0.5	-1.1	-1.1	-1.6	-0.8	-0.8	-1.4	-1.2	-1.4	-0.9	-1.2	-1.4	-1.4	0.2	-0.4	-1.3
Body fat percentage	1.1	4.4	12.5	-2.4	-2.1	-2.2	-1.4	-3.5	-2.4	0.2	-1.1	-2.0	-3.1	-2.3	0.0	-1.8	-2.5	-2.4	-0.0	1.1	-2.9
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	6.9	0.9	0.9	0.2	1.1	-1.6	-0.1	1.5	0.8	0.6	-0.4	0.8	1.3	1.5	0.1	0.4	1.8	2.6	-0.1
Arm fat percentage (left)	1.1	4.4	15.9	-2.0	-1.6	-2.7	-0.8	-4.0	-2.3	1.2	-0.7	-1.5	-3.2	-2.0	0.9	-1.2	-2.2	-1.9	0.3	2.2	-3.0
Type 2 Diabetes (T2D) (2018)	1.0	1.8	4.9	-0.7	-0.3	-1.2	0.6	-2.2	-1.4	1.8	-0.3	-1.3	-1.6	-0.8	1.7	-0.1	-2.1	-0.9	1.8	1.3	-1.4
Medication: Metformin	1.0	1.4	6.1	-0.7	-0.6	-1.1	0.1	-2.5	-1.2	0.6	-0.8	-1.5	-1.7	-0.8	0.4	-0.4	-1.7	-1.2	0.3	1.2	-1.5
Relative age voice broke	1.0	1.5	3.0	-1.6	-1.5	-0.7	-1.7	0.0	-0.7	-1.6	-1.0	-1.1	-0.8	-1.4	-1.6	-1.7	-0.8	-1.2	-0.5	-1.6	-1.0
Hayfever, allergic rhinitis or eczema	1.0	2.2	5.3	2.3	1.6	1.1	1.4	0.8	1.2	1.0	1.4	1.7	1.3	1.9	0.7	2.0	1.9	1.6	-1.0	1.8	1.4
Stomach or abdominal pain in last month	1.0	1.2	2.1	1.2	1.2	0.9	1.3	0.2	0.9	1.2	1.1	1.2	0.8	1.3	1.2	1.5	0.9	1.2	1.2	1.3	0.9
Supplements: Glucosamine	1.0	1.3	2.7	-1.4	-1.4	-0.2	-1.0	-1.2	-0.7	-0.2	-1.1	-0.9	-1.6	-1.6	0.0	-1.4	-1.1	-1.0	-1.1	-0.6	-1.6
Pain all over the body in last month	1.0	1.1	2.1	0.9	1.1	-0.2	1.1	0.9	1.1	1.0	1.1	1.4	1.1	1.2	1.0	1.0	1.2	1.2	1.0	0.5	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	6.9	-2.0	-1.5	-1.2	-1.8	-0.7	-1.1	-1.8	-2.3	-2.1	-1.1	-1.9	-1.9	-2.1	-2.1	-1.9	-0.4	-2.6	-1.3
Comparative body size at age 10	1.0	2.7	9.3	-1.7	-1.3	-1.7	-0.6	-3.0	-1.5	1.3	-0.3	-0.9	-2.5	-1.7	1.0	-0.9	-1.8	-1.6	1.2	1.9	-2.4
Medication: Ibuprofen	1.0	1.2	4.5	1.4	1.3	2.1	1.0	0.7	1.3	0.4	0.9	0.9	1.2	1.2	0.1	1.4	1.0	1.0	0.3	0.9	1.2
Pulse rate, automated reading	1.0	3.2	9.6	0.9	1.2	0.7	0.6	3.1	2.3	0.6	2.3	2.0	2.6	1.6	1.3	0.6	2.4	1.6	-1.8	-1.3	2.4
Family relationship satisfaction	1.0	1.2	4.7	-1.3	-1.2	-1.0	-1.2	0.4	-0.4	-1.0	-1.0	-1.1	-0.4	-1.2	-0.7	-1.5	-1.1	-0.9	-1.3	-2.2	-0.6
Average weekly champagne plus white wine intake	1.0	1.4	5.5	-0.2	-0.5	-0.2	-0.8	-1.5	-1.3	-1.7	-1.6	-1.5	-1.0	-0.4	-2.3	0.1	-1.4	-1.3	-0.6	1.0	-0.8
Supplements: Fish oil (including cod liver oil)	1.0	1.4	2.2	-1.4	-1.5	-0.9	-1.2	-1.1	-1.0	-0.7	-1.2	-1.1	-1.4	-1.5	-0.5	-1.4	-1.4	-1.2	-0.4	-0.6	-1.5
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.8	0.9	1.1	0.6	1.1	1.0	1.3	1.1	1.2	1.3	1.1	1.2	1.2	0.9	1.3	1.2	1.0	0.4	1.1
Blood Red Count	0.9	8.7	44.1	-1.5	-1.8	-0.2	-2.7	4.0	0.8	-4.6	-2.3	-0.8	1.7	-1.0	-3.7	-2.9	0.6	-0.4	-5.4	-6.6	1.0
Tanning	0.9	10.7	16.2	-3.3	-3.4	-2.6	-3.2	-3.7	-3.8	-3.0	-3.7	-3.8	-3.8	-3.2	-3.5	-2.5	-4.0	-3.8	-0.3	-0.5	-3.6
Fluid intelligence score	0.9	1.9	5.0	-0.6	-0.6	-1.1	-0.9	-1.8	-1.8	-1.7	-1.8	-1.9	-1.2	-0.6	-2.2	0.2	-1.9	-1.4	-0.8	0.9	-1.0
Illnesses of mother	0.9	1.1	6.0	1.0	0.9	-0.2	1.2	-0.9	0.1	1.2	0.2	0.3	-0.0	0.9	0.5	1.5	-0.1	0.5	2.5	2.3	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	5.0	0.3	0.1	2.0	-0.2	2.2	1.1	-0.7	1.0	1.2	1.5	0.4	-0.2	-0.3	1.6	0.9	-0.4	-1.7	1.2
Ever highly irritable/argumentative for 2 days	0.9	1.0	4.7	-0.8	-0.8	-0.6	-1.2	1.4	-0.0	-1.9	-0.7	-0.2	0.5	-0.4	-1.6	-1.0	0.2	-0.3	-0.8	-2.2	0.2
Leg fat percentage (right)	0.9	3.4	9.0	-2.1	-1.9	-1.7	-1.4	-3.0	-1.7	-0.3	-1.1	-1.8	-2.7	-2.2	-0.2	-1.8	-2.1	-2.2	-0.1	0.7	-2.6
Medication: Seretide 50 evohaler	0.9	1.0	2.8	-1.1	-0.8	-1.7	-0.9	-1.3	-1.5	-0.2	-0.6	-0.9	-1.2	-0.9	-0.4	-0.8	-1.2	-1.1	0.9	0.2	-1.2
Comparative height size at age 10	0.9	5.1	10.4	-1.6	-1.4	0.5	-1.1	-3.0	-2.6	-1.9	-3.1	-2.7	-2.4	-1.6	-3.0	-0.5	-3.2	-2.2	3.2	1.2	-2.2
Diabetes diagnosed by doctor	0.9	1.5	4.5	-0.9	-0.6	-1.1	0.3	-2.1	-1.4	1.1	-0.6	-1.4	-1.6	-0.8	1.0	-0.3	-2.0	-1.1	1.4	1.0	-1.4
Basal cell carcinoma (self-reported)	0.9	1.1	2.5	1.1	1.0	0.7	1.3	0.7	1.1	0.8	0.9	1.2	0.9	1.1	0.6	1.2	1.2	1.1	1.6	1.2	0.9
Heart disease (siblings)	0.9	1.1	8.7	-0.7	-0.8	-0.5	-0.7	1.5	0.7	-1.0	-0.5	-0.5	0.6	-0.6	-0.4	-1.4	0.0	-0.2	-1.2	-3.0	0.3
Depression (Nagel 2018)	0.8	1.2	6.4	-0.0	0.2	0.9	-0.5	2.1	1.2	-0.2	0.5	0.7	1.6	0.2	0.0	-0.4	0.9	0.7	-1.7	-2.5	1.2
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.5	0.8	0.3	1.2	0.2	0.8	0.3	0.2	1.3	1.4	0.7	0.7	0.0	1.4	1.2	1.2	1.6	0.5	0.7
Number of treatments/medications taken	0.8	1.5	5.2	0.4	0.3	1.1	0.6	2.3	2.0	0.2	1.0	1.4	1.5	0.7	0.6	-0.3	1.7	1.3	0.7	-1.6	1.3
Severe depression (siblings)	0.8	0.9	4.0	0.3	0.3	0.9	-0.0	2.0	1.3	-0.0	0.8	1.0	1.2	0.3	0.4	-0.2	1.2	0.9	-0.7	-1.5	1.0
Diabetes (self-reported)	0.8	1.2	3.6	-0.7	-0.4	-0.8	0.4	-1.9	-1.3	1.0	-0.5	-1.4	-1.3	-0.7	0.9	-0.1	-1.9	-1.0	1.0	1.0	-1.2
Neck or shoulder pain in last month	0.8	1.1	7.5	-0.9	-0.8	-0.1	-1.0	1.6	0.6	-0.9	-0.1	-0.2	0.6	-0.8	-0.2	-1.4	0.1	-0.2	-1.8	-2.7	0.3
Medication: Allopurinol	0.8	1.1	3.6	-0.9	-1.1	0.1	-1.4	0.4	-0.4	-1.9	-1.1	-0.8	-0.3	-1.0	-1.7	-1.3	-0.5	-0.9	-0.9	-1.7	-0.4
Medication for cholesterol	0.8	1.2	5.7	0.2	-0.3	-0.3	0.0	-2.1	-1.1	-0.6	-1.1	-1.3	-1.3	-0.4	-1.4	0.6	-1.1	-0.9	0.1	2.4	-1.1
Number of self-reported non-cancer illnesses	0.8	1.3	3.3	0.5	0.6	0.4	0.8	1.8	1.6	1.0	1.3	1.8	1.2	1.0	1.2	0.2	1.8	1.5	0.1	-0.6	1.1
Medication: Bendroflumethiazide	0.8	1.2	6.8	-1.6	-1.2	-0.9	-1.2	0.9	-0.6	-0.6	-0.3	-0.5	-0.1	-1.1	0.0	-1.8	-0.5	-0.4	-1.4	-2.6	-0.4
Fractured/broken bones in last 5 years	0.8	1.0	2.9	0.5	0.4	0.8	0.4	1.7	1.3	0.6	1.4	1.2	1.2	0.7	1.0	0.1	1.4	1.0	-1.0	-0.7	1.1
HDL Cholesterol	0.7	1.1	2.6	1.1	1.1	1.3	0.6	1.6	1.2	-0.1	1.0	0.9	1.6	1.2	-0.1	1.0	1.2	0.9	0.1	-0.1	1.6
Primary Biliary Cirrhosis	0.7	1.0	2.5	0.8	1.1	0.8	1.1	0.8	1.2	1.0	1.3	1.0	1.1	1.0	0.9	0.8	1.0	0.9	1.6	0.3	1.1
Diabetes (mother)	0.7	0.9	2.9	-0.8	-0.8	0.1	-0.5	-1.7	-1.1	-0.5	-0.6	-1.0	-1.3	-0.7	-0.7	-0.4	-1.0	-1.0	1.2	1.0	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.8	-1.2	-1.1	-0.7	-1.3	-0.2	-0.5	-1.0	-1.0	-0.9	-0.5	-1.2	-0.9	-1.2	-0.9	-1.0	-0.7	-1.7	-0.7
Multivitamins +/- minerals	0.7	0.9	1.9	-0.8	-1.0	-0.6	-0.7	-1.4	-0.9	-0.8	-1.2	-1.2	-1.2	-1.1	-0.9	-0.9	-1.1	-1.1	0.2	-0.3	-1.2
Hair/balding pattern: Pattern 2	0.7	0.8	4.5	1.0	0.7	1.6	1.1	-0.7	0.2	1.0	0.5	0.4	-0.1	0.5	0.6	1.1	0.5	0.6	0.9	2.1	0.0
Father’s age at death	0.7	0.9	2.4	1.3	1.1	1.5	1.0	0.9	0.9	0.3	0.7	0.5	1.3	1.2	0.0	1.3	0.7	0.8	0.5	0.7	1.3
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	1.7	-1.0	-1.1	-1.3	-1.3	-0.7	-1.3	-1.0	-0.9	-0.9	-1.0	-1.2	-0.9	-0.9	-0.9	-0.9	-1.3	-0.7	-1.1
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.3	-1.0	-1.0	-1.1	-0.7	-0.9	-0.9	-0.9	-1.1	-1.0	-1.1	-0.9	-1.0	-0.9	-1.0	-0.8	-0.3	-0.1	-1.1
Forced vital capacity (FVC), Best measure	0.7	2.6	8.4	-1.7	-1.3	-0.6	-1.6	-0.2	-0.9	-1.8	-2.2	-2.0	-0.7	-1.6	-1.8	-1.9	-2.0	-1.7	-0.3	-2.9	-0.9
Number of children fathered	0.7	0.8	1.6	-0.8	-1.1	-0.5	-0.9	-0.9	-0.8	-0.6	-0.8	-0.9	-1.1	-1.3	-0.5	-1.1	-0.8	-0.9	-0.7	-0.5	-1.1
Age at first live birth	0.7	1.2	4.4	1.5	1.4	0.0	1.6	-0.5	0.2	1.5	0.7	0.3	0.3	1.1	1.2	1.7	0.2	0.8	0.5	2.1	0.6
Emphysema/chronic bronchitis	0.7	0.8	4.7	0.4	0.7	0.1	0.8	-0.4	0.3	1.3	0.9	0.9	0.0	0.6	1.2	1.0	0.4	0.6	2.2	1.3	0.2
Medication: Blood pressure	0.7	1.2	8.6	-0.9	-0.6	-1.4	-0.6	2.0	0.4	-0.6	0.0	0.1	0.9	-0.3	-0.0	-1.4	0.4	0.1	-1.3	-2.9	0.6
Age at last live birth	0.7	1.1	4.4	1.0	1.1	0.0	1.5	-0.7	0.2	2.1	0.9	0.4	0.0	0.8	1.9	1.1	0.0	0.6	0.4	1.6	0.2
Friendships satisfaction	0.7	0.8	2.4	1.1	1.2	0.2	1.2	0.4	0.6	1.1	0.6	0.6	0.8	1.2	0.8	1.6	0.3	1.0	0.0	1.2	0.9
Medication: Gliclazide	0.7	0.8	4.4	0.4	0.9	-0.3	1.3	0.4	0.5	1.9	0.6	0.2	0.6	0.5	2.1	0.5	-0.3	0.6	1.0	-0.1	0.6
Average weekly spirits intake	0.6	0.7	4.3	-0.2	0.1	1.2	0.3	-1.0	0.1	1.1	0.8	0.6	-0.6	-0.1	1.1	0.2	0.1	0.1	2.1	1.5	-0.5
Falls in the last year	0.6	0.9	4.3	-1.3	-0.9	-1.5	-0.7	0.5	0.1	0.1	-0.2	-0.2	-0.2	-1.0	0.7	-1.5	-0.2	-0.2	-1.2	-2.1	-0.5
Noisy workplace	0.6	0.7	1.2	-1.0	-1.1	-1.0	-0.9	-0.6	-0.8	-0.8	-0.9	-0.8	-1.0	-0.9	-0.9	-0.9	-0.9	-0.9	-0.3	-0.5	-1.0
Hair/balding pattern: Pattern 4	0.6	1.4	4.3	0.9	1.4	0.2	1.5	-0.1	0.8	2.1	1.1	0.9	0.7	1.3	2.0	1.5	0.5	1.0	0.5	1.6	0.8
Glaucoma (self-reported)	0.6	0.7	1.7	0.3	0.7	1.0	0.6	1.2	1.3	0.7	1.1	0.9	1.1	0.7	0.9	0.2	1.0	0.7	0.2	-0.4	1.0
Medication: Amlodipine	0.6	0.9	4.8	-0.8	-0.7	-1.5	-0.9	1.4	-0.0	-0.5	0.2	0.1	0.5	-0.5	0.1	-1.1	0.4	-0.1	-1.7	-2.2	0.3
High blood pressure (siblings)	0.6	0.9	6.0	-0.8	-0.4	0.8	-0.4	1.8	1.0	-0.1	0.1	0.8	0.7	-0.3	0.3	-1.0	0.7	0.5	-0.8	-2.4	0.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.8	-0.8	-0.7	0.1	-0.3	-1.7	-1.0	0.8	-0.4	-0.7	-1.3	-0.8	0.5	-0.6	-1.1	-0.7	0.6	0.6	-1.2
Angina (self-reported)	0.6	0.8	4.9	-0.3	-0.0	0.6	-0.0	1.7	1.1	-0.1	0.4	0.4	1.0	0.1	0.4	-0.7	0.7	0.4	-0.9	-2.2	0.8
Medication: Omeprazole	0.6	0.7	1.4	0.5	0.7	0.3	0.7	0.8	1.1	0.7	1.0	1.2	0.9	0.9	0.7	0.6	1.1	0.9	1.2	0.3	0.9
Number of full sisters	0.6	0.8	1.6	-0.8	-0.9	-0.1	-0.9	-1.1	-1.0	-0.9	-0.8	-0.9	-1.1	-0.8	-1.3	-0.6	-1.0	-1.0	0.4	0.4	-1.1
Chest pain or discomfort	0.6	0.8	2.7	-1.2	-1.1	-1.3	-1.0	-0.1	-0.3	-0.8	-0.8	-0.5	-0.6	-1.1	-0.3	-1.3	-0.5	-0.6	-0.8	-1.6	-0.7
Eye problems/disorders: Cataract	0.6	0.7	1.7	-0.5	-0.8	0.8	-1.0	-0.9	-1.3	-1.0	-0.7	-0.5	-0.9	-0.6	-1.2	-0.2	-0.7	-0.9	1.0	0.7	-0.9
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.2	-0.5	-0.8	-0.1	-0.7	-0.8	-1.0	-1.3	-1.1	-1.0	-0.9	-0.8	-1.5	-0.6	-0.8	-0.9	0.2	0.2	-0.9
Illnesses of father: High blood pressure	0.6	0.7	4.1	-0.7	-0.6	-1.4	-0.7	1.2	0.2	-0.9	-0.1	0.1	0.2	-0.5	-0.2	-1.2	0.4	-0.1	-1.2	-2.0	0.0
Cholesterol lowering medication	0.6	0.9	1.9	0.5	0.6	1.2	0.6	1.4	1.4	0.7	1.1	0.9	1.2	0.7	1.0	0.2	1.0	0.9	-0.1	-0.8	1.1
Ulcerative Colitis (UC)	0.5	0.8	2.3	-1.1	-1.0	-0.7	-0.8	-0.2	-0.7	-0.9	-1.5	-0.8	-0.6	-0.9	-1.3	-1.1	-0.7	-0.8	-0.4	-1.3	-0.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	3.7	-0.4	-0.7	-0.4	-0.9	1.1	0.2	-1.2	-0.2	-0.0	0.4	-0.3	-0.7	-1.0	0.4	-0.2	-1.7	-1.9	0.2
Taking other prescription medications	0.5	0.7	2.3	0.3	0.4	-0.1	0.6	1.5	1.1	0.5	0.9	1.1	1.1	0.8	0.8	0.2	1.1	1.1	0.1	-0.6	1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.2	-1.0	-1.1	0.5	-0.9	-0.5	-0.4	-0.5	-0.8	-0.4	-0.9	-0.8	-0.6	-0.9	-0.6	-0.5	0.1	-0.5	-0.9
Serious illness, injury or assault to yourself	0.5	0.6	3.1	-0.1	0.1	0.5	-0.2	1.7	0.9	-0.0	0.6	0.6	1.0	0.1	0.4	-0.5	0.6	0.4	-0.4	-1.7	0.8
Hair/balding pattern: Pattern 3	0.5	0.7	5.0	-0.9	-0.7	-0.4	-0.7	1.0	0.3	-0.8	-0.6	-0.3	0.2	-0.6	-0.5	-1.1	-0.1	-0.3	-1.1	-2.2	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.7	-0.5	-0.7	-0.1	-0.8	0.3	-0.2	-0.9	-0.6	-0.6	-0.2	-0.9	-0.7	-1.0	-0.3	-0.4	-1.6	-1.2	-0.4
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	5.8	0.8	0.4	1.4	0.3	-1.4	-0.2	-0.2	-0.2	-0.1	-0.6	0.3	-0.8	1.1	-0.0	-0.1	0.9	2.4	-0.3
Gout (self-reported)	0.5	0.6	2.4	-0.4	-0.8	0.1	-1.0	0.6	-0.1	-1.5	-0.7	-0.5	0.0	-0.7	-1.4	-1.0	-0.0	-0.5	-0.4	-1.4	-0.1
Medication: Aspirin	0.5	0.6	4.2	-0.1	-0.0	-1.1	0.2	1.5	0.6	0.3	0.4	0.1	1.0	0.1	0.8	-0.6	0.3	0.4	-0.5	-2.1	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.2	-0.9	-0.8	-0.5	-0.7	-1.0	-1.0	-0.2	0.1	-0.4	-1.1	-1.0	-0.0	-0.8	-0.5	-0.7	0.9	0.5	-1.1
Medication: Aspirin	0.5	0.7	5.4	-0.3	-0.1	-0.8	-0.0	1.6	0.7	0.1	0.3	0.2	1.0	0.1	0.7	-0.8	0.4	0.3	-0.6	-2.3	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.6	-0.2	-0.1	1.2	-0.8	0.8	0.6	-1.8	-1.0	-0.8	0.7	-0.2	-1.8	-0.5	-0.2	-0.6	-1.0	-1.9	0.5
Alcohol drinker status: Never	0.5	0.6	1.2	0.9	1.0	0.4	1.1	0.8	1.0	0.9	0.6	0.5	0.9	0.8	1.0	0.8	0.6	0.8	-0.7	0.1	0.9
Alcohol drinker status: Previous	0.5	0.6	1.1	0.5	0.7	0.3	0.6	1.0	0.7	0.7	0.8	0.9	1.0	0.8	0.9	0.6	0.8	0.9	0.9	-0.1	0.9
Alzheimer’s Disease (in father)	0.4	0.5	1.0	0.6	0.7	0.8	0.7	0.7	1.0	0.9	0.5	0.8	0.6	0.3	0.8	0.2	0.9	1.0	0.2	-0.2	0.6
Fasting Glucose	0.4	0.5	2.3	-1.0	-0.5	-1.5	-0.4	-0.9	-0.7	0.1	-0.3	-0.9	-0.6	-0.6	0.1	-0.6	-0.8	-0.8	-0.7	-0.1	-0.7
Blood Eosinophil Count	0.4	2.7	5.3	1.6	1.4	0.5	1.8	1.4	1.0	1.7	2.3	1.6	1.8	1.8	1.8	1.7	1.7	1.7	2.3	1.0	1.8
Respiratory disease	0.4	1.0	2.7	0.8	0.7	0.8	0.7	-0.0	0.5	1.1	1.3	1.4	0.3	0.8	1.3	1.0	1.2	1.0	0.9	1.6	0.4
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.1	0.2	0.2	0.5	-0.2	1.2	0.8	-0.3	0.2	0.2	1.1	0.3	-0.2	0.0	0.5	0.4	-1.4	-1.4	0.9
Angina	0.4	0.5	4.2	-0.3	-0.1	0.3	-0.0	1.4	0.9	-0.2	0.1	0.1	0.8	0.1	0.2	-0.7	0.4	0.2	-0.8	-2.0	0.7
Medication for hormone replacement therapy	0.4	0.5	1.6	-0.7	-0.7	0.2	-0.9	-0.7	-0.6	-1.1	-0.6	-0.1	-0.7	-0.7	-1.2	-0.6	0.0	-0.5	0.8	-0.0	-0.8
Diabetes (father)	0.4	0.4	0.7	-0.7	-0.7	-0.7	-0.5	-0.6	-0.6	-0.5	-0.6	-0.7	-0.8	-0.8	-0.7	-0.8	-0.7	-0.7	0.5	-0.1	-0.8
Illnesses of siblings	0.4	0.6	4.8	1.2	0.9	-0.2	0.7	-0.7	-0.2	0.3	0.5	-0.0	0.1	0.9	-0.2	1.4	0.2	0.2	0.1	2.2	0.3
Lung cancer (father)	0.4	0.5	2.5	-0.0	0.1	0.1	0.3	-1.1	-0.8	-0.1	-0.9	-0.7	-0.7	0.1	-0.7	0.8	-1.0	-0.3	-0.0	1.6	-0.5
Wheeze or whistling in the chest in last year	0.4	0.7	2.4	-0.4	-0.3	-0.9	0.2	-1.4	-0.8	1.4	0.1	0.0	-1.2	-0.5	1.5	-0.1	-0.5	-0.1	0.2	1.1	-1.1
Shortness of breath walking on level ground	0.4	0.5	1.0	0.7	0.9	-0.3	0.8	0.7	0.6	0.9	0.7	0.8	0.7	0.8	0.9	0.7	0.6	1.0	0.1	0.4	0.7
Illnesses of siblings: Diabetes	0.4	0.5	1.5	-0.2	-0.2	-0.8	-0.0	-1.2	-1.1	0.2	-0.4	-0.6	-0.8	-0.2	-0.1	0.4	-1.1	-0.5	1.1	1.2	-0.6
Ever depressed for a whole week	0.4	0.5	2.3	-0.4	-0.3	0.9	-0.6	1.4	0.2	-0.8	0.1	0.4	0.8	0.1	-0.4	-0.4	0.3	0.2	0.2	-1.5	0.6
Commuting to job workplace: Cycle	0.4	0.4	1.9	-0.3	-0.3	-0.0	-0.6	0.9	0.2	-1.1	-0.5	-0.5	0.5	-0.2	-1.1	-0.4	-0.1	-0.1	-0.9	-1.4	0.4
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.6	-0.4	-0.4	-1.6	-0.6	-0.5	-1.1	-1.1	-1.4	-1.3	-0.4	-0.4	-1.3	0.1	-1.3	-0.7	-1.0	-0.1	-0.3
Alzheimer’s Disease (in mother)	0.3	0.3	1.4	-0.3	-0.6	0.5	-0.4	-1.2	-0.7	-0.1	-0.4	-0.3	-0.9	-0.7	0.1	-0.4	-0.4	-0.5	-0.6	0.4	-0.9
Ovarian Cancer	0.3	0.3	1.4	0.0	0.2	-0.2	0.2	-0.6	-0.5	1.2	0.7	0.2	-0.4	0.0	1.2	0.3	-0.3	0.1	0.9	0.9	-0.3
Age at First Birth	0.3	0.5	2.5	0.4	0.2	-0.5	0.3	-1.2	-1.0	-0.0	-0.6	-0.5	-0.6	0.2	-0.4	1.2	-0.7	-0.1	-0.1	1.6	-0.3
Mean Putamen Volume	0.3	0.3	1.0	0.1	0.1	0.8	0.3	-1.0	-0.6	0.6	-0.0	-0.1	-0.4	0.1	0.4	0.6	-0.4	-0.1	1.0	0.8	-0.3
Waist Hip Ratio (WHR)	0.3	1.4	7.7	0.7	0.9	2.8	0.8	1.6	1.0	0.2	0.9	0.8	1.4	0.9	0.4	0.6	0.8	0.9	2.1	-0.5	1.3
Lung FVC	0.3	1.4	7.6	0.3	0.6	0.9	0.0	2.1	2.0	0.2	0.6	0.9	1.5	0.3	0.8	-0.6	1.1	0.7	-1.0	-2.8	1.2
Medication: Co-codamol	0.3	0.3	1.7	-0.3	-0.2	-0.1	-0.4	1.3	0.7	-0.1	0.5	0.5	0.6	-0.1	0.2	-0.7	0.5	0.3	-0.4	-1.3	0.4
Had other major operations	0.3	0.4	0.9	0.6	0.4	0.7	0.4	1.0	0.8	0.4	0.7	0.8	0.8	0.6	0.4	0.3	0.9	0.8	-0.1	-0.4	0.7
Time employed in main current job	0.3	0.3	0.8	0.9	0.8	0.1	0.8	0.5	0.2	0.4	0.2	0.3	0.7	0.7	0.5	0.8	0.4	0.6	-0.5	0.1	0.7
Alcohol intake frequency.	0.3	0.6	1.4	-1.2	-0.8	-0.4	-0.8	-0.3	-0.4	-0.5	-0.9	-1.0	-0.5	-0.9	-0.4	-1.0	-1.2	-0.9	0.1	-1.2	-0.6
Leg pain on walking	0.3	0.3	1.6	-0.4	-0.2	-1.0	-0.4	1.2	0.3	-0.0	0.0	0.2	0.4	-0.2	0.2	-0.6	0.0	0.2	-0.9	-1.3	0.2
Ever had bowel cancer screening	0.3	0.4	1.9	-0.7	-0.6	-0.3	-0.6	0.3	-0.2	-0.7	-0.9	-0.4	0.0	-0.5	-0.6	-0.7	-0.5	-0.3	-0.1	-1.4	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.1	-0.8	-0.7	-1.4	-0.7	-0.6	-1.0	-0.2	-0.5	-0.2	-0.9	-0.7	-0.2	-0.8	-0.4	-0.5	0.5	-0.3	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.5	-0.9	-0.7	0.5	-0.6	-0.0	-0.0	0.0	-0.2	-0.0	-0.4	-0.9	0.2	-1.2	-0.1	-0.3	0.9	-1.2	-0.5
Average weekly beer plus cider intake	0.3	0.4	1.1	-0.5	-0.5	-0.7	-0.3	-1.1	-0.9	0.1	-0.3	-0.0	-1.0	-0.4	-0.1	-0.3	-0.2	-0.2	0.9	0.9	-0.9
Myopia	0.3	0.4	1.7	0.8	0.8	0.0	0.7	0.5	-0.0	1.0	0.7	0.4	0.6	0.7	1.3	0.8	0.2	0.6	-0.5	0.2	0.6
Pain experienced in last month	0.3	0.4	1.1	-0.3	-0.4	-0.4	-0.3	-1.0	-1.1	-0.6	-0.7	-0.9	-0.8	-0.4	-0.7	-0.2	-0.8	-0.8	0.1	0.6	-0.7
Depressed Affect (Nagel 2018)	0.2	0.5	2.1	0.1	0.1	0.3	-0.2	1.4	0.9	-0.0	0.5	0.7	1.0	0.3	0.2	-0.2	0.8	0.6	-1.1	-1.1	0.8
Crohns Disease (2017)	0.2	0.5	1.9	-1.4	-1.0	0.0	-0.5	-0.4	-0.0	0.2	-0.6	-0.4	-0.8	-1.1	0.2	-1.3	-0.6	-0.7	-0.3	-0.9	-0.9
Irritable Bowel Disease (IBD)	0.2	0.5	1.8	-1.3	-1.0	-0.3	-0.6	-0.0	-0.2	-0.3	-0.9	-0.4	-0.5	-0.9	-0.4	-1.2	-0.4	-0.6	-0.3	-1.3	-0.6
Fed-up feelings	0.2	0.4	1.1	0.3	0.4	0.3	0.3	0.3	0.8	0.9	0.9	1.1	0.4	0.4	0.8	0.3	0.9	0.7	0.7	0.5	0.4
Qualifications: CSEs or equivalent	0.2	0.3	0.6	-0.6	-0.5	-0.4	-0.3	-0.8	-0.8	0.2	-0.5	-0.2	-0.8	-0.5	0.1	-0.5	-0.4	-0.4	0.7	0.1	-0.7
Medication: Simvastatin	0.2	0.3	0.7	-0.8	-0.6	-0.1	-0.5	-0.7	-0.6	0.2	-0.0	-0.2	-0.6	-0.6	0.4	-0.6	-0.4	-0.5	0.4	-0.3	-0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.4	0.5	0.4	1.2	-0.3	0.1	-0.8	-1.0	-0.1	-0.4	0.5	0.6	-1.0	1.0	-0.3	-0.1	-0.6	0.1	0.6
Asthma	0.2	0.5	1.4	0.1	0.2	0.8	0.1	-0.3	0.2	0.9	1.0	1.2	-0.1	0.2	1.2	0.3	0.7	0.5	0.8	1.0	-0.1
Medication: Cholesterol lowering	0.2	0.4	1.6	-0.7	-0.4	-1.2	-0.2	0.1	-0.3	0.6	0.0	-0.2	-0.1	-0.5	1.1	-0.8	-0.5	-0.2	-0.4	-1.2	-0.2
Loud music exposure frequency	0.2	0.3	0.6	-0.7	-0.7	-0.2	-0.5	-0.8	-0.1	-0.1	-0.3	-0.4	-0.7	-0.6	0.2	-0.6	-0.4	-0.6	-0.6	-0.2	-0.7
Eye problems/disorders: None of the above	0.2	0.3	1.9	0.1	-0.0	-0.7	0.3	-0.8	-0.3	0.4	-0.3	-0.6	-0.6	-0.4	0.4	-0.1	-0.5	-0.2	-1.4	0.4	-0.6
Supplements: Vitamin C	0.2	0.3	0.7	-0.4	-0.5	-0.3	0.0	-0.9	-0.1	0.5	-0.4	-0.4	-0.8	-0.6	0.4	-0.5	-0.6	-0.3	0.8	0.1	-0.7
Mood swings	0.2	0.3	1.4	0.1	0.1	-0.7	-0.1	1.0	0.5	-0.1	0.4	0.6	0.6	0.3	0.2	-0.1	0.8	0.5	-1.2	-0.7	0.5
Asthma (self-reported)	0.2	0.5	1.6	0.2	0.3	0.8	0.1	-0.2	0.2	0.9	1.2	1.2	-0.0	0.3	1.3	0.4	0.8	0.5	0.7	1.0	0.0
Osteoporosis (self-reported)	0.2	0.3	1.6	-0.4	-0.4	0.8	-0.6	0.9	0.7	-0.3	0.1	0.4	0.3	-0.3	-0.0	-0.7	0.2	0.0	-0.6	-1.3	0.1
Osteoarthritis (self-reported)	0.2	0.3	0.8	-0.1	-0.1	0.7	0.0	0.7	0.8	0.2	0.4	0.8	0.2	-0.1	0.6	-0.6	0.9	0.5	0.1	-0.6	0.1
Hearing aid user	0.2	0.3	1.9	0.0	-0.4	0.5	-0.5	0.2	0.3	-1.3	-0.5	-0.1	-0.1	-0.1	-1.4	-0.3	0.2	-0.2	-0.1	-0.1	-0.1
Mother’s age at death	0.2	0.3	1.0	0.6	0.5	1.0	0.4	0.5	0.4	-0.2	0.0	-0.3	0.8	0.7	-0.3	0.6	-0.1	0.1	-0.6	-0.2	0.8
Number of operations (self-reported)	0.2	0.3	2.4	0.7	0.2	1.5	0.4	-0.2	0.3	-0.2	0.1	0.4	0.1	0.4	-0.5	0.6	0.6	0.3	0.4	1.0	0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.5	-0.2	-0.3	0.7	-0.4	-0.4	-0.3	-0.2	-0.2	-0.1	-0.3	-0.5	0.1	-0.5	-0.1	-0.2	-0.5	-0.3	-0.4
Triglycerides	0.1	0.2	0.8	-0.1	0.0	-0.5	0.1	0.8	0.4	-0.1	-0.0	0.2	0.5	0.1	0.1	-0.3	0.4	0.3	-0.1	-0.9	0.4
Hypothyroidism (self reported)	0.1	0.3	0.9	-0.3	-0.6	0.1	-0.0	-0.9	-0.6	0.4	-0.2	-0.2	-0.9	-0.5	0.3	-0.4	-0.4	-0.3	0.5	0.6	-0.8
Hair Pigment	0.1	3.0	5.2	1.9	1.7	1.5	1.4	2.2	2.0	0.7	2.3	1.9	2.2	1.8	1.0	1.4	2.3	1.7	1.3	0.4	2.1
Medication: Levothyroxine sodium	0.1	0.2	1.4	-0.3	-0.6	-0.6	-0.4	0.3	-0.0	-0.4	-0.3	0.1	-0.1	-0.1	-0.4	-0.5	0.3	-0.1	-1.2	-0.6	-0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.6	0.3	0.1	-0.1	-0.2	-0.1	-0.0	-0.3	0.4	0.7	0.0	0.3	-0.3	0.4	0.7	0.2	0.0	0.8	0.1
Depression (self-reported)	0.1	0.1	0.3	0.5	0.3	0.4	0.2	0.5	0.5	-0.1	-0.0	0.2	0.5	0.3	-0.0	0.2	0.3	0.4	-0.2	-0.4	0.5
Headache pain in last month	0.1	0.2	1.1	0.7	0.4	1.0	0.2	0.0	0.2	-0.2	-0.3	0.3	0.2	0.4	-0.6	0.6	0.3	0.5	-0.9	0.4	0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.5	0.2	0.2	0.4	0.1	-0.2	0.2	-0.5	-0.2	-0.3	-0.0	0.2	-0.6	0.4	-0.1	-0.1	0.4	0.7	0.1
Loneliness, isolation	0.1	0.1	0.3	-0.1	-0.0	-0.0	-0.1	0.4	0.6	0.3	0.3	0.3	0.4	0.2	0.2	-0.1	0.3	0.3	-0.6	-0.3	0.3
Guilty feelings	0.1	0.1	0.7	0.5	-0.0	0.8	0.0	0.2	0.3	-0.2	-0.0	-0.0	0.1	-0.1	-0.3	-0.1	0.3	0.1	-0.7	0.0	0.0
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.7	-0.6	-0.6	0.1	-0.5	0.5	0.4	0.0	0.3	0.4	-0.2	-0.4	0.4	-0.9	0.3	-0.0	-0.2	-0.6	-0.3
Age started oral contraceptive pill	0.1	0.1	0.9	0.3	0.1	0.9	0.2	0.3	-0.0	0.2	0.0	-0.1	0.3	0.1	0.3	0.1	0.0	0.1	-0.9	-0.3	0.3
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.3	0.2	-0.0	0.2	0.2	0.6	0.3	0.1	0.1	0.4	0.2	0.3	0.0	-0.0	0.6	0.4	-0.2	-0.1	0.3
Health satisfaction	0.0	0.1	0.2	-0.3	-0.3	-0.2	-0.3	0.3	-0.4	-0.3	-0.0	-0.2	0.0	-0.1	-0.2	-0.2	-0.3	-0.2	0.1	-0.4	0.0
High cholesterol (Self-reported)	0.0	0.0	0.3	-0.0	-0.0	0.1	0.1	0.3	0.1	0.1	0.1	-0.1	0.3	0.2	0.2	-0.0	-0.1	0.1	-0.0	-0.5	0.3
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.4	0.0	-0.1	-0.4	-0.2	-0.0	-0.1	-0.2	-0.2	0.1	-0.1	-0.1	-0.0	-0.2	0.0	-0.1	-0.6	-0.2	-0.1

Hub : Genes

AS3MT

Models

Trait associations