[Hub]/) : Traits : Whole body fat-free mass : ← →

chr6:124,741,508-127,355,237

Best TWAS P=2.82e-45 · Best GWAS P=5.72e-46 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CENPW	0.04	0.06	lasso	10	0.06	2.4e-07	14.08	-14.1	2.8e-45	-0.99	0.02	0.98	TRUE
10	GTEx	Thyroid	HEY2	0.22	0.24	lasso	6	0.23	1.0e-17	-9.03	-9.2	2.6e-20	-0.08	0.01	0.99	TRUE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	CENPW	0.04	0.06	blup	35	0.05	9.2e-07	14.01	-13.8	2.0e-43	-0.98	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CENPW	0.04	0.05	lasso	5	0.05	2.6e-06	14.20	-13.6	4.1e-42	-0.98	0.02	0.98	FALSE
12	METSIM	Adipose	CENPW	0.02	0.02	blup	189	0.01	8.3e-03	14.18	-9.6	1.2e-21	-0.74	0.02	0.76	FALSE
14	METSIM	Adipose	NCOA7	0.05	0.05	enet	5	0.05	1.9e-07	7.07	9.4	6.0e-21	0.23	0.95	0.02	FALSE
9	GTEx	Testis	HEY2	0.31	0.17	lasso	5	0.19	7.4e-09	-9.03	-9.1	1.3e-19	-0.07	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HEY2	0.15	0.20	lasso	10	0.21	6.7e-25	-9.09	-9.0	1.5e-19	-0.07	0.01	0.99	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	HEY2	0.10	0.12	enet	15	0.13	9.8e-17	8.59	-8.3	7.9e-17	-0.06	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	HEY2	0.03	0.04	lasso	3	0.02	3.8e-03	7.94	-8.2	2.5e-16	-0.07	0.01	0.98	FALSE
5	GTEx	Esophagus Muscularis	HINT3	0.08	0.00	enet	14	0.00	2.9e-01	8.81	-7.5	5.9e-14	-0.11	0.07	0.04	FALSE
7	GTEx	Pancreas	HEY2	0.28	0.11	lasso	3	0.10	3.5e-05	-6.55	-7.3	2.1e-13	-0.05	0.09	0.91	FALSE
6	GTEx	Heart Atrial Appendage	CENPW	0.17	0.01	enet	15	0.06	1.8e-03	14.18	-7.2	5.7e-13	-0.70	0.03	0.54	FALSE
11	GTEx	Vagina	CENPW	0.24	-0.01	lasso	8	-0.01	7.9e-01	5.83	7.0	1.7e-12	0.40	0.04	0.07	FALSE
13	METSIM	Adipose	HEY2	0.02	0.04	lasso	1	0.02	1.6e-04	-6.61	-6.6	3.9e-11	-0.06	0.02	0.97	FALSE
8	GTEx	Skin Sun Exposed Lower leg	HINT3	0.08	0.01	lasso	4	0.03	2.0e-03	-4.88	-6.5	8.6e-11	-0.19	0.22	0.14	FALSE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	HEY2	0.09	0.06	lasso	8	0.06	2.3e-03	-6.55	-6.4	1.2e-10	-0.04	0.03	0.76	FALSE
3	GTEx	Artery Coronary	TPD52L1	0.31	-0.01	enet	19	0.05	7.0e-03	0.15	-6.4	1.4e-10	-0.15	0.03	0.54	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HEY2	0.05	0.05	blup	36	0.05	4.9e-06	-6.55	-5.5	3.7e-08	-0.04	0.16	0.83	FALSE
4	GTEx	Breast Mammary Tissue (Female)	HINT3	0.39	-0.01	enet	16	0.08	2.2e-03	-3.22	-5.3	1.4e-07	-0.13	0.13	0.07	FALSE