TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
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→
chr7:22,946,782-24,382,726
Best TWAS P=7.56e-18 · Best GWAS P=1.67e-21 conditioned to 0.00134
23M
23.2M
23.4M
23.6M
23.8M
24M
24.2M
24.4M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Esophageal Carcinoma
TRA2A
0.18
0.02
blup
40
0.05
0.012
-9.2
-8.6
7.6e-18
0.64
0.00
0.59
TRUE
3
The Cancer Genome Atlas
Soft Tissue Sarcoma
RPS2P32
0.08
0.02
blup
27
0.02
0.031
-6.4
7.0
2.6e-12
-0.70
0.02
0.38
TRUE
1
GTEx
Esophagus Mucosa
CCDC126
0.12
0.03
lasso
7
0.01
0.043
-7.6
7.0
2.4e-12
-0.66
0.05
0.76
FALSE