Best TWAS P=7.56e-18 · Best GWAS P=1.67e-21 conditioned to 0.00134
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CCDC126 | 0.12 | 0.03 | lasso | 7 | 0.01 | 0.043 | -7.6 | 7.0 | 2.4e-12 | -0.66 | 0.05 | 0.76 | FALSE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | TRA2A | 0.18 | 0.02 | blup | 40 | 0.05 | 0.012 | -9.2 | -8.6 | 7.6e-18 | 0.64 | 0.00 | 0.59 | TRUE |
| 3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | RPS2P32 | 0.08 | 0.02 | blup | 27 | 0.02 | 0.031 | -6.4 | 7.0 | 2.6e-12 | -0.70 | 0.02 | 0.38 | TRUE |