[Hub]/) : Traits : Whole body fat-free mass : ← →

chr7:70,996,097-73,789,730

Best TWAS P=3.05e-15 · Best GWAS P=1.64e-15 conditioned to 0.0586

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	GTEx	Thyroid	MLXIPL	0.23	0.14	lasso	7	0.15	2.1e-11	6.87	7.9	3.0e-15	0.73	0.10	0.90	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC30	0.13	0.07	enet	32	0.07	2.7e-09	5.96	6.5	6.1e-11	0.36	1.00	0.00	TRUE
18	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CALN1	0.37	0.04	enet	10	0.25	3.1e-07	-6.06	5.1	2.7e-07	0.05	0.01	0.96	TRUE
14	METSIM	Adipose	MLXIPL	0.12	0.14	lasso	4	0.13	1.8e-19	7.59	7.8	4.3e-15	0.80	0.08	0.92	FALSE
5	GTEx	Cells Transformed fibroblasts	MLXIPL	0.13	0.06	enet	6	0.09	2.2e-07	7.52	7.8	4.8e-15	0.77	0.08	0.92	FALSE
10	GTEx	Spleen	NCF1B	0.22	0.10	enet	9	0.08	5.1e-03	7.52	-7.7	1.8e-14	-0.88	0.02	0.65	FALSE
9	GTEx	Skin Sun Exposed Lower leg	MLXIPL	0.12	0.09	lasso	4	0.06	6.1e-06	7.49	7.6	3.3e-14	0.69	0.15	0.84	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	MLXIPL	0.04	0.03	lasso	1	0.02	2.3e-03	7.58	7.6	3.5e-14	0.83	0.00	0.91	FALSE
2	GTEx	Adipose Subcutaneous	MLXIPL	0.11	0.07	enet	16	0.07	1.6e-06	6.87	7.5	4.9e-14	0.70	0.13	0.86	FALSE
3	GTEx	Adipose Visceral Omentum	MLXIPL	0.16	0.02	lasso	3	0.03	7.8e-03	6.86	7.4	1.2e-13	0.67	0.40	0.54	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	MLXIPL	0.11	0.11	lasso	3	0.06	2.7e-04	7.52	7.4	1.8e-13	0.62	0.08	0.85	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	MLXIPL	0.06	0.05	lasso	2	0.05	5.1e-10	7.58	7.2	5.2e-13	0.77	0.00	1.00	FALSE
11	GTEx	Testis	MLXIPL	0.10	0.00	lasso	3	0.00	3.3e-01	5.14	6.9	6.7e-12	0.58	0.05	0.20	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	BCL7B	0.05	0.01	blup	5	0.03	1.3e-03	7.58	-6.8	1.2e-11	-0.93	0.00	0.63	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	MLXIPL	0.08	0.05	enet	4	0.05	5.3e-06	7.58	6.5	8.9e-11	0.70	0.00	0.98	FALSE
4	GTEx	Adipose Visceral Omentum	NSUN5	0.07	0.03	enet	11	0.04	4.0e-03	7.58	6.1	8.2e-10	0.48	0.05	0.38	FALSE
7	GTEx	Lung	MLXIPL	0.10	0.07	enet	14	0.07	6.3e-06	6.87	5.7	1.5e-08	0.50	0.21	0.50	FALSE
6	GTEx	Heart Left Ventricle	MLXIPL	0.14	0.00	enet	24	0.01	1.3e-01	0.44	5.6	1.8e-08	0.38	0.14	0.26	FALSE
12	GTEx	Testis	VPS37D	0.15	0.01	lasso	5	0.03	2.7e-02	-4.96	-5.4	5.4e-08	-0.33	0.13	0.06	FALSE