[Hub]/) : Traits : Whole body fat-free mass : ← →

chr7:75,913,086-78,122,616

Best TWAS P=1.34e-16 · Best GWAS P=1.56e-13 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DTX2P1-UPK3BP1-PMS2P11	0.18	0.09	enet	21	0.12	6.1e-15	6.663	8.3	1.3e-16	0.82	0.00	1.00	TRUE
7	GTEx	Brain Frontal Cortex BA9	GSAP	0.38	0.22	lasso	6	0.21	3.0e-06	5.757	-6.8	1.2e-11	-0.13	0.14	0.20	TRUE
4	GTEx	Artery Aorta	GSAP	0.19	0.07	lasso	2	0.04	2.8e-03	5.803	-6.2	6.0e-10	-0.03	0.26	0.04	TRUE
16	GTEx	Thyroid	AC007000.12	0.13	0.08	enet	24	0.07	2.6e-06	-4.744	-5.9	4.4e-09	-0.18	0.66	0.02	TRUE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	PION	0.08	0.05	lasso	3	0.05	8.5e-07	5.803	-5.8	5.0e-09	-0.06	0.00	1.00	TRUE
9	GTEx	Heart Left Ventricle	GSAP	0.21	0.02	lasso	5	0.03	9.3e-03	4.669	-5.7	1.1e-08	-0.01	0.12	0.04	TRUE
18	ROSMAP	Brain Pre-frontal Cortex	GSAP	0.36	0.27	lasso	7	0.28	1.5e-35	5.757	-5.7	1.6e-08	-0.02	0.98	0.02	TRUE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM60	0.02	0.02	lasso	1	0.02	2.3e-05	5.408	-5.4	6.4e-08	0.00	0.00	1.00	TRUE
19	ROSMAP	Brain Pre-frontal Cortex	RSBN1L	0.09	0.07	enet	42	0.08	9.9e-11	-4.084	-5.4	7.7e-08	-0.03	0.48	0.52	TRUE
11	GTEx	Ovary	TMEM60	0.23	0.19	enet	7	0.13	5.2e-04	-5.174	-5.3	1.2e-07	0.01	0.09	0.53	TRUE
17	GTEx	Whole Blood	TMEM60	0.05	0.04	enet	7	0.03	5.4e-04	-4.836	-5.2	2.0e-07	-0.02	0.24	0.75	TRUE
14	GTEx	Thyroid	TMEM60	0.06	0.04	lasso	8	0.04	8.2e-04	-5.003	-5.1	2.7e-07	-0.01	0.21	0.75	TRUE
5	GTEx	Artery Tibial	TMEM60	0.07	0.05	enet	12	0.02	6.6e-03	-4.983	-5.1	2.8e-07	0.00	0.16	0.63	TRUE
2	GTEx	Adipose Subcutaneous	RP11-467H10.2	0.12	0.00	lasso	6	0.01	2.1e-02	3.039	6.0	2.4e-09	0.05	0.13	0.04	FALSE
15	GTEx	Thyroid	GSAP	0.19	0.08	lasso	3	0.07	3.3e-06	5.803	-5.9	3.4e-09	-0.02	0.88	0.03	FALSE
10	GTEx	Muscle Skeletal	GSAP	0.20	0.12	lasso	2	0.12	1.8e-11	5.757	-5.9	4.0e-09	-0.04	0.98	0.02	FALSE
6	GTEx	Brain Cerebellum	GSAP	0.38	0.30	lasso	4	0.31	6.4e-10	5.654	-5.8	4.9e-09	-0.01	0.91	0.02	FALSE
13	GTEx	Skin Sun Exposed Lower leg	DTX2P1	0.16	0.03	enet	22	0.05	4.8e-05	7.382	5.7	1.1e-08	0.70	0.00	0.99	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	PION	0.13	0.07	enet	9	0.08	3.4e-09	5.803	-5.6	1.9e-08	-0.03	0.00	1.00	FALSE
3	GTEx	Adipose Visceral Omentum	TMEM60	0.20	0.13	lasso	8	0.11	2.3e-06	-5.134	-5.4	7.3e-08	-0.01	0.24	0.75	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM60	0.02	0.03	blup	29	0.02	6.8e-03	5.408	-5.4	7.7e-08	-0.01	0.00	0.92	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	GSAP	0.18	0.01	lasso	6	0.08	2.5e-05	-2.241	-5.3	1.4e-07	-0.05	0.22	0.06	FALSE
8	GTEx	Brain Putamen basal ganglia	GSAP	0.48	0.20	lasso	12	0.15	2.2e-04	5.803	-5.2	2.1e-07	-0.11	0.15	0.09	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PMS2L11	0.05	0.02	enet	3	0.06	2.5e-07	0.021	5.2	2.1e-07	0.71	0.01	0.97	FALSE