Best TWAS P=5.59e-08 · Best GWAS P=1.13e-10 conditioned to 0.000504
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TPM2 | 0.13 | 0.06 | lasso | 4 | 0.09 | 1.7e-11 | -5.0 | -5.2 | 2.1e-07 | -0.49 | 0.76 | 0.24 | FALSE |
| 2 | GTEx | Artery Aorta | SPAG8 | 0.11 | 0.10 | lasso | 7 | 0.06 | 2.0e-04 | 5.0 | -5.2 | 1.6e-07 | -0.86 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Liver | NPR2 | 0.18 | 0.04 | lasso | 3 | 0.02 | 1.1e-01 | 5.2 | -5.1 | 2.7e-07 | -0.88 | 0.03 | 0.79 | FALSE |
| 4 | GTEx | Thyroid | RP11-112J3.16 | 0.26 | 0.13 | lasso | 7 | 0.13 | 1.9e-10 | 4.9 | -5.4 | 5.6e-08 | -0.83 | 0.39 | 0.61 | TRUE |