TWAS hub - TPM2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1290	0.0370	1.9e-09	0.065	0.091	0.083	0.090	0.094	2.3e-08	3.5e-11	2.4e-10	4.3e-11	1.7e-11
2	GTEx	Adrenal Gland	0.2890	0.0745	1.5e-05	0.216	NA	0.233	NA	0.250	2.8e-08	NA	6.9e-09	NA	1.8e-09
3	GTEx	Brain Caudate basal ganglia	0.4430	0.0990	1.0e-05	0.213	NA	0.278	NA	0.271	9.1e-07	NA	1.3e-08	NA	2.0e-08
4	GTEx	Brain Cerebellar Hemisphere	0.5640	0.0980	7.5e-08	0.545	NA	0.554	NA	0.562	1.3e-16	NA	5.6e-17	NA	2.7e-17
5	GTEx	Brain Cerebellum	0.6340	0.0830	8.4e-11	0.428	NA	0.515	NA	0.526	5.4e-14	NA	1.3e-17	NA	4.0e-18
6	GTEx	Brain Nucleus accumbens basal ganglia	0.2930	0.0750	2.1e-05	0.302	NA	0.262	NA	0.289	8.3e-09	NA	1.1e-07	NA	2.0e-08
7	GTEx	Cells Transformed fibroblasts	0.1490	0.0550	1.9e-03	0.086	NA	0.088	NA	0.066	5.0e-07	NA	3.8e-07	NA	1.1e-05
8	GTEx	Muscle Skeletal	0.0641	0.0315	5.7e-03	0.017	NA	0.009	NA	0.018	7.5e-03	NA	3.6e-02	NA	6.2e-03
9	GTEx	Pancreas	0.1120	0.0500	6.7e-03	0.154	NA	0.077	NA	0.139	4.8e-07	NA	3.6e-04	NA	1.8e-06
10	METSIM	Adipose	0.1222	0.0298	3.1e-12	0.134	0.112	0.134	0.133	0.135	2.0e-19	2.1e-16	1.6e-19	2.8e-19	1.1e-19
11	NTR	Blood	0.0402	0.0113	7.5e-09	0.041	0.028	0.038	0.037	0.042	2.6e-13	1.8e-09	2.7e-12	6.4e-12	2.3e-13
12	ROSMAP	Brain Pre-frontal Cortex	0.5523	0.0416	0.0e+00	0.599	0.573	0.613	0.602	0.608	5.3e-97	1.9e-90	1.1e-100	1.2e-97	3.0e-99
13	YFS	Blood	0.4613	0.0348	0.0e+00	0.497	0.469	0.504	0.496	0.504	1.6e-190	5.9e-176	1.1e-194	7.8e-190	1.6e-194
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1100	0.0450	3.6e-05	0.081	0.097	0.108	NA	0.105	2.1e-05	3.5e-06	1.0e-06	NA	1.3e-06
15	TCGA	Brain Lower Grade Glioma	0.1088	0.0304	0.0e+00	0.156	0.168	0.165	NA	0.173	2.4e-17	1.1e-18	2.6e-18	NA	3.5e-19
16	TCGA	Thyroid Carcinoma	0.0400	0.0230	9.9e-03	0.018	0.011	0.011	NA	0.017	5.9e-03	2.8e-02	2.4e-02	NA	8.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Blood White Count	6.5	48.4	74.0	-4.5	-6.6	-5.0	-8.0	-8.1	-7.3	3.8	8.6	-8.0	-7.2	-8.0	-7.6	-7.8	-7.1	-6.7	-4.7
Mother’s age at death	5.9	7.4	9.7	-2.7	-3.0	-3.0	-3.0	-2.9	-3.1	2.9	1.8	-3.0	-3.0	-2.8	-2.9	-3.0	-1.4	-3.0	0.2
Diabetes (self-reported)	5.6	8.6	11.7	-3.0	-3.3	-2.6	-3.3	-3.4	-3.2	1.1	2.9	-3.3	-3.2	-3.0	-3.2	-3.1	-2.7	-3.1	-1.3
Mouth/teeth dental problems: Dentures	5.5	9.3	11.7	-3.1	-3.3	-2.1	-3.1	-3.2	-3.3	2.1	2.7	-3.1	-3.2	-3.4	-3.4	-3.4	-2.5	-3.4	-3.0
Depression (self-reported)	5.5	6.6	10.0	2.1	2.5	2.1	2.9	2.8	2.9	-1.2	-2.8	2.8	2.7	3.2	2.8	3.1	2.3	2.7	1.6
Ever smoked	5.4	9.5	12.9	3.5	3.3	2.6	3.3	3.4	3.2	-1.9	-3.4	3.3	3.3	3.2	3.6	3.2	2.8	3.3	-0.1
Guilty feelings	5.3	8.0	11.0	2.7	3.0	2.3	3.3	3.3	2.9	-0.5	-3.0	3.2	3.1	2.8	3.3	3.1	3.0	3.0	1.2
Medication: Metformin	5.2	7.4	9.9	-2.8	-3.0	-2.4	-3.0	-3.1	-2.9	0.3	3.1	-3.0	-3.0	-2.7	-3.0	-2.9	-2.6	-2.9	-1.0
Diabetes diagnosed by doctor	4.8	8.0	11.3	-2.5	-3.1	-2.3	-3.3	-3.4	-3.1	1.3	3.2	-3.3	-3.1	-3.0	-3.1	-3.1	-2.2	-2.9	-1.0
Medication: Gliclazide	4.5	5.1	8.2	-2.2	-2.4	-1.9	-2.5	-2.7	-2.4	2.2	2.9	-2.4	-2.4	-2.0	-2.5	-2.2	-1.7	-2.3	0.0
Heart attack/myocardial infarction (self-reported)	4.3	5.5	7.4	2.2	2.6	2.3	2.7	2.7	2.6	-1.2	-2.5	2.7	2.6	2.4	2.6	2.5	1.7	2.6	-0.4
Hip circumference	4.2	18.3	23.1	-4.3	-4.6	-4.8	-4.8	-4.8	-4.7	2.6	4.1	-4.8	-4.7	-4.5	-4.6	-4.6	-2.8	-4.5	1.4
Frequency of depressed mood in last 2 weeks	4.0	5.6	8.0	2.1	2.5	1.9	2.7	2.6	2.7	-0.3	-2.0	2.6	2.6	2.6	2.8	2.8	2.5	2.5	1.1
Medication for cholesterol	4.0	6.1	8.2	-2.0	-2.7	-1.7	-2.8	-2.7	-2.8	0.4	2.9	-2.9	-2.8	-2.8	-2.9	-2.9	-2.3	-2.6	0.2
Angina	3.8	5.0	7.2	1.8	2.3	1.9	2.6	2.7	2.4	-0.9	-2.7	2.6	2.4	2.4	2.3	2.5	2.1	2.3	0.8
Body Mass Index (BMI) (2010)	3.6	5.0	6.6	-1.6	-2.2	-2.5	-2.5	-2.6	-2.2	0.6	2.3	-2.4	-2.3	-2.5	-2.5	-2.4	-2.5	-2.3	-1.2
Heel T-Score	3.6	28.9	43.7	4.5	5.5	3.6	6.2	6.4	5.6	-0.6	-6.6	6.2	5.8	5.9	6.1	5.7	5.8	5.6	1.8
Type 2 Diabetes (T2D) (2018)	3.6	6.7	10.0	-1.7	-2.8	-2.3	-3.2	-3.1	-2.8	0.2	3.0	-3.2	-3.0	-2.8	-2.8	-3.1	-1.7	-2.7	-0.6
Diverticular disease/diverticulitis (self-reported)	3.6	4.3	7.9	-2.6	-2.4	-2.8	-2.1	-2.1	-2.2	0.0	1.2	-2.0	-2.2	-1.9	-2.2	-2.1	-1.2	-2.5	-1.8
Bipolar Disorder (2018)	3.5	5.5	10.6	1.2	2.1	1.3	2.7	2.7	2.3	-1.4	-3.3	2.7	2.3	2.8	2.5	2.7	2.9	2.3	1.1
Blood Platelet Count	3.5	40.8	98.4	-2.8	-5.3	-4.6	-7.8	-8.1	-6.1	4.3	9.9	-7.6	-6.2	-7.2	-6.7	-6.9	-6.2	-5.7	-2.1
Worry too long after embarrassment	3.5	5.8	9.1	1.5	2.5	2.2	2.7	2.4	2.8	-1.2	-2.0	2.7	2.7	2.8	2.9	3.0	2.2	2.6	1.1
Angina (self-reported)	3.5	4.5	7.0	1.7	2.2	1.7	2.5	2.6	2.3	-0.7	-2.6	2.4	2.3	2.3	2.2	2.4	2.0	2.2	0.8
Triglycerides	3.4	5.6	12.0	-2.5	-2.4	-2.2	-2.1	-2.2	-2.3	3.5	1.9	-2.0	-2.1	-2.5	-2.5	-2.3	-2.8	-2.3	-1.8
Medication: Co-codamol	3.2	3.7	6.3	-1.7	-2.1	-2.5	-2.1	-2.0	-2.2	0.8	1.7	-2.1	-2.1	-1.9	-2.1	-2.1	-1.4	-1.9	-1.6
Heart attack	3.2	4.1	5.6	1.8	2.2	1.9	2.4	2.4	2.2	-1.3	-2.3	2.4	2.3	2.1	2.2	2.1	1.3	2.2	-0.7
Chronotype (morning person)	3.1	7.1	17.4	-2.8	-2.7	-1.7	-2.5	-2.5	-2.6	1.0	2.4	-2.4	-2.6	-2.7	-2.8	-2.7	-2.9	-2.9	-4.2
Neuroticism score	3.1	6.4	9.7	1.7	2.4	2.3	2.9	2.8	2.8	-1.3	-2.5	2.9	2.7	2.9	2.9	3.1	2.5	2.7	0.9
Arm fat mass (right)	2.9	12.1	15.8	-3.0	-3.7	-3.8	-3.9	-4.0	-3.8	2.9	3.5	-3.9	-3.8	-3.7	-3.7	-3.7	-2.3	-3.6	1.0
Loud music exposure frequency	2.9	3.2	5.2	1.1	1.5	1.2	2.0	1.8	1.9	-1.9	-1.5	2.0	1.8	2.3	1.9	2.2	1.8	1.5	1.7
Illnesses of father: High blood pressure	2.9	3.6	5.6	2.0	1.9	2.0	2.0	1.8	2.2	-1.2	-1.3	2.1	2.1	2.1	2.3	2.4	1.4	1.9	-0.1
Depression (Nagel 2018)	2.8	4.2	7.6	0.8	2.0	1.6	2.5	2.4	2.4	-0.2	-2.1	2.5	2.2	2.7	2.5	2.8	1.7	2.0	-0.1
Irritability	2.8	4.7	6.8	1.2	1.9	2.4	2.5	2.5	2.1	-0.7	-2.2	2.4	2.2	2.5	2.4	2.6	2.2	2.4	1.5
Worry (Nagel 2018)	2.7	5.8	8.2	2.1	2.4	2.9	2.6	2.7	2.5	-0.8	-2.6	2.5	2.5	2.5	2.7	2.6	2.5	2.6	0.5
Leg fat-free mass (left)	2.7	14.2	28.7	-5.4	-4.6	-3.7	-3.9	-4.1	-4.4	1.7	3.1	-3.9	-4.3	-3.5	-4.0	-3.6	-2.1	-4.4	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	6.0	1.0	1.6	2.4	2.2	2.2	2.1	-1.6	-1.7	2.2	1.9	2.3	2.1	2.4	1.3	1.6	0.3
Leg predicted mass (left)	2.7	14.3	29.4	-5.4	-4.6	-3.7	-3.9	-4.1	-4.4	1.7	3.1	-3.9	-4.3	-3.5	-4.1	-3.6	-2.0	-4.5	0.3
Fluid intelligence score	2.7	5.6	9.1	3.0	2.8	2.7	2.4	2.4	2.6	-2.2	-1.6	2.3	2.6	1.9	2.5	2.4	1.8	2.9	0.8
Arm fat mass (left)	2.7	11.3	15.4	-2.9	-3.5	-3.7	-3.8	-3.9	-3.6	2.6	3.5	-3.8	-3.7	-3.5	-3.6	-3.5	-2.3	-3.5	1.0
Hair/balding pattern: Pattern 2	2.6	3.4	6.6	2.6	2.3	2.0	1.9	2.0	2.1	-0.6	-0.9	1.9	2.1	1.7	2.1	1.6	1.1	2.3	0.6
Weight	2.6	13.0	17.4	-4.2	-4.1	-4.0	-3.9	-3.9	-4.1	2.4	3.0	-3.9	-4.1	-3.6	-3.9	-3.7	-2.2	-4.0	1.0
Mouth/teeth dental problems: Mouth ulcers	2.6	4.2	7.2	2.7	2.5	1.5	2.1	2.1	2.1	0.9	-1.6	2.0	2.3	1.8	2.3	1.7	2.4	2.4	1.3
Medication: Aspirin	2.6	3.4	5.1	1.4	1.8	2.3	2.1	2.0	2.0	-1.4	-1.8	2.0	1.9	2.1	2.1	2.1	1.4	1.9	0.1
Intelligence (Savage-Jansen 2018)	2.5	7.8	11.7	3.4	3.3	2.1	2.8	2.8	3.0	-1.9	-2.3	2.7	3.1	2.6	3.0	2.8	2.0	3.4	2.7
Frequency of tenseness / restlessness in last 2 weeks	2.5	3.9	5.8	1.5	2.1	1.5	2.3	2.2	2.2	-0.1	-1.7	2.2	2.2	2.3	2.3	2.4	1.9	2.3	-0.0
Medication: Aspirin	2.5	3.3	4.5	1.5	1.8	2.0	2.0	1.9	2.0	-0.9	-1.9	2.0	1.9	2.1	2.1	2.1	1.4	2.0	-0.0
Verbal and Numeric Reasoning (VNR)	2.4	5.6	8.1	2.6	2.8	2.0	2.5	2.6	2.6	-1.4	-2.2	2.4	2.6	2.2	2.6	2.5	2.2	2.8	1.4
Arm fat percentage (right)	2.4	9.3	13.7	-1.6	-2.9	-3.3	-3.6	-3.6	-3.1	3.0	3.7	-3.6	-3.2	-3.4	-3.3	-3.3	-2.2	-2.8	1.2
Suffer from ‘nerves’	2.4	3.7	5.8	1.1	1.7	2.2	2.1	2.1	2.0	-1.8	-2.4	2.0	1.8	2.3	2.0	2.2	1.9	1.8	0.9
Leg fat-free mass (right)	2.4	12.7	28.1	-5.3	-4.4	-3.5	-3.7	-3.8	-4.1	1.2	2.9	-3.6	-4.1	-3.3	-3.8	-3.4	-2.0	-4.3	-0.2
Leg predicted mass (right)	2.4	12.9	28.3	-5.3	-4.4	-3.6	-3.7	-3.8	-4.1	1.3	2.9	-3.7	-4.1	-3.3	-3.9	-3.4	-2.0	-4.3	-0.2
Medication: Bendroflumethiazide	2.4	3.6	5.9	1.9	2.1	2.4	2.0	1.9	2.0	-0.1	-1.7	2.0	2.1	2.1	2.3	2.1	1.4	2.0	0.2
HbA1C	2.3	2.6	4.6	1.0	1.5	1.2	1.7	1.8	1.5	-1.2	-1.7	1.6	1.5	1.9	1.7	1.9	1.4	1.6	2.1
Neuroticism (2016)	2.3	3.3	6.3	1.6	1.6	1.5	1.8	1.9	1.8	-2.5	-1.5	1.8	1.7	1.5	1.7	1.8	2.2	1.7	2.1
Past tobacco smoking	2.3	4.3	5.9	-2.4	-2.1	-1.9	-2.3	-2.3	-2.1	1.3	2.4	-2.3	-2.1	-2.1	-2.4	-2.1	-2.0	-2.1	-0.3
Whole body fat mass	2.3	9.4	12.5	-2.6	-3.1	-3.5	-3.4	-3.4	-3.3	3.0	2.9	-3.4	-3.3	-3.2	-3.3	-3.2	-1.8	-3.1	1.5
Had major operations	2.3	2.7	6.0	-1.3	-1.8	-2.5	-1.7	-1.7	-1.8	0.5	0.6	-1.6	-1.6	-2.0	-1.9	-2.0	-1.5	-1.7	-0.9
Vascular/heart problems diagnosed by doctor	2.3	6.4	12.7	-2.1	-2.5	-2.4	-2.7	-2.7	-2.6	1.8	3.6	-2.7	-2.6	-2.7	-2.9	-2.7	-2.5	-2.5	0.0
BMI	2.2	12.6	18.5	-2.4	-3.5	-3.8	-4.2	-4.3	-3.6	2.6	4.2	-4.2	-3.8	-3.7	-3.9	-3.7	-2.9	-3.5	0.2
Number of treatments/medications taken	2.2	4.0	5.9	1.7	2.2	1.2	2.2	2.1	2.3	0.4	-1.8	2.3	2.3	2.4	2.4	2.4	1.8	2.3	0.3
Pain all over the body in last month	2.2	2.4	4.6	0.7	1.5	0.6	1.8	1.7	1.6	0.4	-1.7	1.8	1.7	2.1	1.9	2.0	1.1	1.7	-1.1
Basal metabolic rate	2.2	12.4	26.1	-5.1	-4.3	-3.6	-3.6	-3.7	-4.1	1.4	2.7	-3.6	-4.0	-3.3	-3.7	-3.4	-2.0	-4.2	0.3
Leg fat mass (left)	2.2	8.5	11.8	-2.2	-2.9	-3.4	-3.3	-3.3	-3.1	3.0	2.9	-3.3	-3.1	-3.0	-3.1	-3.1	-1.7	-2.9	1.3
Neuroticism (Nagel 2018)	2.1	5.0	7.4	1.7	2.2	2.0	2.5	2.5	2.4	-0.5	-2.3	2.5	2.3	2.4	2.6	2.6	2.7	2.4	1.0
Waist Hip Ratio (WHR)	2.1	9.2	13.2	3.0	3.3	2.9	3.3	3.5	3.0	0.6	-3.2	3.2	3.3	3.0	3.2	3.1	2.5	3.6	2.6
Neuroticism	2.1	5.1	6.9	1.6	2.3	2.2	2.5	2.5	2.4	-0.3	-2.4	2.5	2.4	2.4	2.6	2.5	2.6	2.4	1.1
Leg fat mass (right)	2.1	8.2	11.4	-2.2	-2.9	-3.4	-3.2	-3.2	-3.1	3.0	2.8	-3.2	-3.1	-3.0	-3.0	-3.1	-1.7	-2.8	1.3
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	4.1	-2.0	-1.8	-1.1	-1.5	-1.4	-1.8	0.1	1.0	-1.6	-1.7	-1.7	-1.7	-1.6	-2.0	-1.7	-1.9
Whole body water mass	2.1	11.7	27.5	-5.2	-4.2	-3.4	-3.4	-3.5	-4.0	1.0	2.5	-3.5	-4.0	-3.1	-3.6	-3.3	-2.1	-4.1	-0.2
Trunk fat mass	2.0	8.7	12.2	-2.6	-3.0	-3.5	-3.2	-3.2	-3.1	2.9	2.7	-3.2	-3.1	-3.1	-3.2	-3.1	-1.6	-2.9	2.0
Whole body fat-free mass	2.0	11.3	27.0	-5.2	-4.2	-3.4	-3.4	-3.4	-4.0	1.0	2.4	-3.4	-3.9	-3.0	-3.6	-3.2	-1.9	-4.1	-0.0
Impedance of leg (left)	1.9	9.1	13.8	3.7	3.6	2.5	3.4	3.7	3.3	-0.1	-3.3	3.2	3.4	2.7	3.1	2.7	2.2	3.5	1.8
Nervous feelings	1.9	3.6	4.5	1.6	1.8	2.0	2.0	2.0	2.0	-1.5	-1.7	1.9	1.9	2.1	2.1	2.1	2.1	2.0	1.6
Family relationship satisfaction	1.9	2.3	3.7	1.0	1.6	1.3	1.8	1.8	1.6	0.2	-1.3	1.9	1.7	1.9	1.7	1.9	1.1	1.6	0.6
Arm fat percentage (left)	1.9	7.7	11.2	-1.5	-2.6	-3.1	-3.2	-3.3	-2.8	2.7	3.4	-3.2	-2.8	-3.0	-3.0	-3.0	-1.8	-2.6	1.3
Schizophrenia vs Biploar Disorder	1.8	2.4	4.0	-1.1	-1.6	-0.9	-1.6	-1.7	-1.5	-0.7	1.6	-1.5	-1.5	-1.8	-1.7	-1.7	-1.6	-1.7	-2.0
Cardiovascular Disease	1.8	6.1	12.5	2.1	2.4	1.9	2.6	2.6	2.4	-1.1	-3.5	2.6	2.5	2.4	2.7	2.5	3.2	2.5	1.8
Sensitivity / hurt feelings	1.8	3.1	5.8	0.9	1.8	1.4	2.0	1.8	1.9	0.5	-1.5	2.0	2.0	2.0	2.0	2.0	2.4	1.8	0.8
Ever had hysterectomy (womb removed)	1.8	2.1	3.0	1.1	1.7	1.2	1.6	1.5	1.7	-0.8	-1.2	1.7	1.7	1.6	1.6	1.6	0.8	1.6	0.9
Body mass index (BMI)	1.8	7.7	11.2	-2.0	-2.8	-2.9	-3.2	-3.4	-2.9	2.4	3.1	-3.2	-3.0	-2.8	-2.9	-2.9	-2.0	-2.7	0.5
Trunk fat-free mass	1.8	10.3	25.9	-5.1	-4.0	-3.3	-3.1	-3.2	-3.8	0.6	2.1	-3.2	-3.7	-2.8	-3.4	-3.0	-2.0	-3.9	-0.2
Trunk predicted mass	1.8	10.2	25.6	-5.1	-4.0	-3.3	-3.1	-3.2	-3.8	0.7	2.1	-3.2	-3.7	-2.9	-3.4	-3.0	-2.0	-3.9	-0.1
Arm fat-free mass (left)	1.8	9.1	21.7	-4.7	-3.8	-3.1	-3.0	-3.0	-3.6	1.2	1.9	-3.0	-3.5	-2.7	-3.2	-2.9	-1.8	-3.7	-0.1
Arm predicted mass (left)	1.8	9.3	21.6	-4.7	-3.8	-3.1	-3.1	-3.1	-3.6	1.0	2.0	-3.1	-3.6	-2.7	-3.2	-2.9	-2.0	-3.7	-0.3
Alzheimer’s Disease (in father)	1.7	1.9	6.7	-0.7	-1.0	-0.5	-1.6	-1.8	-1.2	0.8	2.6	-1.6	-1.2	-1.5	-1.2	-1.5	-1.5	-1.0	-0.8
Age at First Birth	1.7	2.5	5.1	0.2	1.2	1.1	1.7	1.8	1.3	0.8	-2.3	1.6	1.4	1.8	1.8	1.7	1.8	1.5	1.9
Waist circumference	1.7	6.1	8.4	-2.0	-2.4	-2.8	-2.7	-2.6	-2.7	2.9	2.2	-2.8	-2.6	-2.6	-2.6	-2.6	-1.3	-2.3	1.9
Serious illness, injury or assault of a close relative in last 2 years	1.7	2.0	5.3	1.9	1.8	0.5	1.1	1.0	1.6	0.3	-0.4	1.1	1.6	1.4	1.5	1.3	1.3	1.5	2.3
Ever highly irritable/argumentative for 2 days	1.7	2.0	3.1	0.8	1.4	1.1	1.7	1.8	1.7	-1.4	-1.4	1.7	1.5	1.7	1.6	1.7	0.3	1.3	0.4
Mouth/teeth dental problems: Bleeding gums	1.7	2.3	3.2	1.5	1.6	0.5	1.7	1.7	1.6	-0.1	-1.8	1.6	1.6	1.4	1.6	1.5	1.8	1.6	1.3
Glaucoma (self-reported)	1.7	2.0	5.4	-2.3	-1.6	-1.7	-1.1	-1.2	-1.4	1.3	1.4	-1.1	-1.4	-1.0	-1.3	-1.0	-1.4	-1.7	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	3.1	-1.3	-1.4	-1.1	-1.6	-1.8	-1.4	1.7	1.8	-1.6	-1.4	-1.6	-1.4	-1.4	-1.4	-1.1	-0.6
Bipolar Disorder (2011)	1.6	1.6	3.5	1.0	1.4	1.9	1.4	1.4	1.4	-0.2	-1.3	1.4	1.4	1.6	1.4	1.6	0.0	0.0	0.0
Impedance of leg (right)	1.6	7.9	11.9	3.4	3.3	2.3	3.1	3.4	3.0	0.2	-3.0	2.9	3.1	2.5	2.9	2.4	2.2	3.3	2.5
Time employed in main current job	1.6	1.8	6.0	1.3	1.2	0.2	1.2	1.2	1.2	-1.2	-0.9	1.2	1.2	1.3	1.2	1.2	2.1	1.3	2.5
Number of live births	1.6	2.2	6.2	-1.3	-1.2	-0.9	-1.2	-1.2	-1.4	1.7	0.9	-1.2	-1.3	-1.5	-1.3	-1.5	-2.4	-1.5	-2.5
Arm predicted mass (right)	1.6	8.2	22.0	-4.7	-3.5	-3.1	-2.7	-2.8	-3.4	1.3	1.7	-2.8	-3.3	-2.5	-2.9	-2.7	-1.7	-3.5	-0.2
Average weekly red wine intake	1.6	2.3	7.5	1.4	1.2	1.2	1.5	1.4	1.5	-2.7	-1.7	1.5	1.4	1.4	1.5	1.5	1.6	1.4	0.3
Asthma (self-reported)	1.6	3.2	10.1	-2.7	-2.1	-3.2	-1.4	-1.6	-1.8	2.2	0.0	-1.3	-1.7	-1.4	-1.5	-1.4	-1.3	-1.9	-0.5
Number of self-reported non-cancer illnesses	1.6	2.8	5.6	1.1	1.6	0.4	1.8	1.8	1.5	0.8	-2.4	1.8	1.7	1.9	1.9	1.9	2.0	1.6	1.4
Medication: Blood pressure	1.6	3.1	4.6	1.8	1.9	2.1	1.8	1.7	2.0	-0.4	-2.1	1.9	2.0	1.9	2.1	2.0	0.9	1.9	-0.3
Basal cell carcinoma (self-reported)	1.6	1.9	5.7	1.4	1.4	0.9	1.2	1.3	1.2	2.4	-0.8	1.2	1.4	1.3	1.5	1.2	1.6	1.5	1.4
Alzheimer’s Disease (in mother)	1.5	1.8	5.1	0.3	1.0	0.2	1.5	1.4	1.4	0.7	-1.4	1.6	1.3	1.7	1.5	1.6	2.3	1.0	1.0
Relative age of first facial hair	1.5	3.0	5.0	1.8	1.9	0.9	1.9	1.7	1.9	0.7	-0.8	1.9	2.0	2.2	1.9	2.2	1.6	2.1	1.0
Supplements: Zinc	1.5	1.6	2.6	1.6	1.6	1.3	1.2	1.3	1.4	-0.4	-0.7	1.2	1.4	1.2	1.4	1.2	1.3	1.4	1.0
High blood pressure	1.5	4.1	9.0	1.7	1.9	2.2	2.1	2.0	2.0	-1.8	-3.0	2.1	2.0	2.1	2.3	2.0	2.0	2.0	0.1
Medication: Ramipril	1.5	1.9	5.3	1.4	1.5	1.1	1.4	1.6	1.3	-1.2	-2.3	1.4	1.3	1.3	1.5	1.3	1.0	1.4	0.2
Pulse rate	1.5	2.5	4.1	1.6	1.8	0.9	1.8	1.8	1.8	0.9	-1.2	1.7	1.8	1.6	1.7	1.9	1.1	2.0	0.8
Asthma	1.5	3.0	9.5	-2.7	-2.1	-3.1	-1.3	-1.5	-1.8	2.1	-0.0	-1.3	-1.7	-1.2	-1.4	-1.3	-1.2	-1.8	-0.6
Tense / ‘highly strung’	1.5	2.5	6.8	0.1	1.2	0.7	2.0	1.9	1.6	-1.1	-2.6	2.0	1.5	1.9	1.6	1.9	1.6	1.3	-0.3
Medication for cholesterol, blood pressure or diabetes	1.5	2.4	3.8	-1.2	-1.5	-1.1	-1.8	-1.7	-1.6	0.4	1.6	-1.8	-1.7	-1.9	-1.6	-1.9	-1.9	-1.6	0.3
Medication: Blood pressure	1.5	2.7	3.4	1.7	1.8	1.8	1.7	1.7	1.7	-0.8	-1.7	1.7	1.8	1.7	1.8	1.7	1.6	1.8	-0.7
Hypertension (Self-reported)	1.5	4.2	8.9	1.8	1.9	2.3	2.1	2.1	2.0	-1.4	-3.0	2.1	2.0	2.0	2.3	2.1	2.2	2.1	0.1
Illnesses of siblings: Diabetes	1.5	1.9	5.4	-1.1	-1.0	-0.8	-1.5	-1.7	-1.2	2.1	2.3	-1.4	-1.1	-1.1	-1.3	-1.1	-1.2	-1.1	0.6
Average weekly beer plus cider intake	1.5	2.2	6.8	-1.8	-1.5	-0.6	-1.1	-1.0	-1.3	0.4	0.4	-1.1	-1.4	-1.4	-1.3	-1.5	-2.6	-1.6	-2.4
Type 2 Diabetes (T2D) (2012)	1.4	1.6	4.4	-0.6	-1.0	-1.4	-1.5	-1.5	-1.2	2.1	1.5	-1.5	-1.1	-1.4	-1.3	-1.4	-0.8	-0.9	0.2
Trunk fat percentage	1.4	5.5	10.5	-1.5	-2.1	-2.9	-2.5	-2.5	-2.3	3.2	2.2	-2.5	-2.3	-2.5	-2.4	-2.4	-1.0	-2.1	2.4
Had other major operations	1.4	1.8	2.8	1.6	1.5	1.6	1.3	1.3	1.3	-0.0	-0.9	1.3	1.4	1.2	1.7	1.3	0.9	1.6	1.3
Worrier / anxious feelings	1.4	2.6	4.2	1.0	1.7	1.5	1.8	1.6	1.7	0.6	-1.5	1.7	1.8	1.8	1.9	2.0	1.4	2.0	0.9
Body fat percentage	1.4	5.6	9.7	-1.2	-2.0	-2.9	-2.6	-2.6	-2.3	3.1	2.4	-2.7	-2.3	-2.5	-2.5	-2.5	-1.2	-2.0	2.0
Arm fat-free mass (right)	1.4	7.4	21.1	-4.6	-3.4	-2.9	-2.6	-2.6	-3.2	0.9	1.5	-2.6	-3.2	-2.3	-2.8	-2.5	-1.5	-3.4	-0.0
Emphysema/chronic bronchitis	1.4	1.6	2.8	0.1	-1.2	-1.6	-1.4	-1.3	-1.2	-0.1	1.0	-1.4	-1.3	-1.7	-1.6	-1.7	-1.4	-1.3	-0.0
Breast cancer (self-reported)	1.4	1.6	2.7	-1.0	-1.4	-0.5	-1.4	-1.3	-1.5	-1.0	0.7	-1.4	-1.4	-1.6	-1.5	-1.6	-1.1	-1.3	-1.1
Hearing aid user	1.4	1.6	3.0	-1.2	-1.4	-1.2	-1.4	-1.5	-1.4	0.5	1.2	-1.4	-1.4	-1.0	-1.4	-1.1	-1.7	-1.2	-0.8
Fractured/broken bones in last 5 years	1.4	1.7	3.3	0.5	1.1	1.1	1.4	1.4	1.1	0.8	-1.8	1.4	1.2	1.4	1.5	1.3	1.6	1.0	1.8
Bipolar Disorder or Schizophrenia	1.3	3.3	5.1	1.0	1.9	1.5	2.1	2.0	1.9	0.4	-2.1	2.2	2.1	1.9	1.8	1.9	2.3	1.9	0.6
Fasting Glucose	1.3	1.5	3.8	-0.3	-1.0	-1.4	-1.4	-1.6	-1.0	-1.2	2.0	-1.4	-1.1	-1.3	-1.3	-1.2	-1.1	-1.0	0.8
Systolic Blood Pressure	1.3	6.4	10.8	1.4	2.3	2.9	2.6	2.6	2.4	-1.5	-3.3	2.7	2.5	3.0	2.8	2.7	3.3	2.0	1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	8.2	0.6	1.3	-0.1	2.0	2.0	1.5	0.0	-2.9	2.0	1.6	1.9	1.8	1.7	2.7	1.4	1.6
Serious illness, injury or assault to yourself	1.3	1.5	3.5	1.3	1.2	1.6	1.2	1.3	1.3	-0.3	-1.0	1.2	1.2	1.2	1.4	1.1	1.9	1.2	0.1
Medication: Atenolol	1.3	1.7	3.9	1.3	1.2	0.8	1.4	1.4	1.2	-0.8	-2.0	1.4	1.3	1.1	1.3	1.3	1.6	1.3	-0.8
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	6.5	1.7	1.2	1.7	1.3	1.2	1.4	-2.5	-0.8	1.3	1.3	1.5	1.5	1.5	1.6	1.3	0.8
High blood pressure (siblings)	1.3	1.8	2.8	1.4	1.4	1.6	1.4	1.5	1.3	-0.1	-1.1	1.4	1.3	1.6	1.7	1.4	1.2	1.3	1.3
Miserableness	1.3	2.2	3.7	1.0	1.3	1.3	1.7	1.6	1.6	-1.3	-1.6	1.6	1.5	1.9	1.7	1.9	0.8	1.7	0.4
Pain type(s) experienced in last month: Hip pain	1.3	1.6	7.6	1.5	1.3	1.0	1.0	1.0	1.3	-2.8	-0.9	1.0	1.1	1.3	1.2	0.9	0.7	1.3	0.6
Cholesterol lowering medication	1.3	2.0	4.2	1.2	1.5	2.1	1.6	1.7	1.5	-0.9	-1.7	1.6	1.5	1.2	1.5	1.3	0.3	1.4	-0.7
Medication: Levothyroxine sodium	1.2	2.0	3.1	-1.2	-1.5	-1.8	-1.6	-1.5	-1.4	0.0	1.5	-1.7	-1.6	-1.4	-1.6	-1.6	-1.1	-1.2	-0.6
Hearing difficulty/problems with background noise	1.2	2.0	3.2	0.8	1.3	-0.0	1.6	1.4	1.5	0.6	-1.5	1.6	1.5	1.6	1.5	1.7	1.5	1.4	1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	8.9	0.6	1.2	-0.1	1.8	1.9	1.4	0.6	-3.0	1.8	1.5	1.7	1.6	1.5	2.2	1.3	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.0	0.9	1.4	1.1	1.4	1.1	1.6	0.5	-0.9	1.4	1.5	1.8	1.7	2.0	1.1	1.5	0.5
Hair/balding pattern: Pattern 4	1.2	2.9	5.0	1.5	1.9	0.9	1.9	2.0	1.8	-1.1	-2.2	1.9	1.9	1.8	1.8	1.8	1.8	1.7	0.6
Medication: Allopurinol	1.2	1.5	4.5	-2.1	-1.5	-0.9	-0.9	-0.9	-1.3	0.1	-0.5	-1.0	-1.2	-1.2	-1.5	-1.2	-1.0	-1.5	-1.6
Osteoarthritis (self-reported)	1.2	1.6	3.4	-0.0	1.1	1.0	1.6	1.7	1.0	0.6	-1.9	1.5	1.2	1.4	1.5	1.4	1.0	1.2	0.1
Wears glasses or contact lenses	1.2	1.4	3.1	-0.4	-0.9	-0.7	-1.5	-1.6	-1.2	0.6	1.8	-1.5	-1.1	-1.4	-1.2	-1.2	-1.5	-0.7	0.4
Risk taking	1.2	1.7	5.2	1.2	1.1	1.0	1.2	1.3	1.3	-2.3	-1.6	1.2	1.1	1.3	1.0	1.2	1.4	1.0	1.2
Mean Putamen Volume	1.1	1.3	1.8	-1.0	-1.3	-0.9	-1.3	-1.2	-1.3	0.2	1.0	-1.3	-1.4	-0.9	-1.3	-1.0	-1.1	-1.3	-0.9
Illnesses of mother	1.1	1.3	3.1	-0.8	-1.2	-0.6	-1.2	-1.2	-1.2	-0.5	1.0	-1.2	-1.2	-1.3	-1.3	-1.3	-1.8	-1.1	-1.0
Peak expiratory flow (PEF)	1.1	2.5	5.2	0.2	1.3	0.9	1.9	2.1	1.5	-0.7	-2.3	1.9	1.5	1.7	1.6	1.6	1.5	1.3	1.9
Pulse wave reflection index	1.1	1.3	2.9	-1.4	-1.0	-1.6	-1.1	-1.3	-1.2	1.7	0.9	-1.1	-1.0	-1.0	-0.9	-1.1	-0.3	-1.2	0.9
Health satisfaction	1.1	1.5	3.4	0.2	0.7	0.7	1.4	1.2	1.0	-1.8	-1.7	1.3	1.0	1.3	1.3	1.4	1.3	0.9	-1.0
Medication for pain relief, constipation, heartburn	1.1	1.8	3.3	-1.2	-1.4	-1.0	-1.6	-1.8	-1.5	0.8	1.8	-1.5	-1.5	-1.1	-1.4	-1.1	-0.9	-1.6	0.4
Supplements: Calcium	1.1	1.2	3.5	0.6	1.2	1.9	1.2	1.2	1.1	-0.4	-0.8	1.2	1.2	1.3	1.4	1.1	0.3	1.1	0.1
Impedance of whole body	1.1	5.4	7.7	2.8	2.7	1.8	2.5	2.8	2.5	-0.0	-2.4	2.4	2.6	1.9	2.3	2.0	1.9	2.7	2.2
Ovarian Cancer	1.0	1.3	4.2	-0.8	-1.0	-0.7	-1.2	-1.4	-1.1	1.4	2.1	-1.1	-1.0	-1.1	-1.3	-0.8	-1.4	-0.9	-0.3
Coronary Artery Disease (CAD)	1.0	1.2	2.7	0.7	1.0	1.3	1.2	1.1	1.2	-0.8	-0.8	1.3	1.1	1.6	1.1	1.4	0.9	1.0	0.0
Medication for hormone replacement therapy	1.0	1.1	2.5	-0.1	0.6	-0.2	1.0	0.8	1.0	-1.5	-0.9	1.1	0.9	1.6	1.1	1.3	1.4	0.8	-1.1
Qualifications: CSEs or equivalent	1.0	1.4	2.8	-1.2	-1.3	-0.6	-1.4	-1.5	-1.2	-0.0	1.7	-1.4	-1.3	-1.1	-1.3	-1.1	-0.4	-1.1	0.6
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	2.9	-1.0	-1.4	-1.5	-1.5	-1.3	-1.4	-0.4	1.0	-1.6	-1.6	-1.6	-1.5	-1.7	-1.4	-1.3	-1.4
Medication: Amlodipine	1.0	1.4	4.2	1.5	1.0	1.5	1.0	1.1	1.1	-2.1	-1.3	1.0	0.9	1.1	1.2	1.1	0.7	0.8	0.3
Heart disease (mother)	1.0	1.3	2.6	0.4	0.8	1.3	1.2	1.2	1.1	-1.6	-1.6	1.1	0.9	1.2	1.2	1.0	0.8	0.9	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	2.8	1.7	1.1	1.3	0.7	0.9	0.8	0.6	-0.0	0.6	0.9	0.5	0.8	0.5	1.6	1.1	1.6
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.5	-0.8	-1.1	-1.3	-1.2	-1.4	-1.1	1.1	1.6	-1.1	-1.1	-1.0	-1.0	-1.0	-0.3	-1.1	0.5
Diastolic blood pressure, automated reading	1.0	3.2	6.6	0.4	1.3	1.2	2.1	1.9	1.9	-0.6	-2.6	2.2	1.7	2.2	2.0	2.1	2.2	1.2	1.2
Ever depressed for a whole week	1.0	1.3	2.1	0.6	1.1	-0.3	1.2	1.2	1.3	-0.4	-1.4	1.3	1.1	1.3	1.1	1.3	1.4	0.8	1.3
Severe depression (siblings)	0.9	1.0	2.9	0.4	0.8	0.7	1.1	1.1	0.8	0.2	-1.1	1.1	0.9	1.2	1.1	1.2	1.7	0.8	0.5
Fed-up feelings	0.9	1.7	3.0	1.2	1.2	1.6	1.4	1.4	1.3	-0.4	-0.5	1.4	1.3	1.5	1.6	1.7	1.2	1.3	1.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	4.9	0.1	0.5	0.7	1.2	1.4	0.8	-0.6	-2.2	1.2	0.7	1.2	1.1	0.9	1.3	0.4	1.0
Alcohol intake versus 10 years previously	0.9	1.4	2.2	1.5	1.4	0.7	1.2	1.2	1.4	-0.6	-0.4	1.1	1.3	1.1	1.0	1.2	1.2	1.4	1.2
Qualifications: College or University degree	0.9	2.8	6.1	2.5	1.8	2.0	1.4	1.4	1.7	-2.4	-1.0	1.4	1.6	1.4	1.7	1.5	1.7	1.8	0.7
Illnesses of father: Heart disease	0.9	1.2	4.0	0.5	0.8	0.6	1.2	1.1	0.9	0.4	-1.4	1.2	1.0	1.5	1.2	1.3	2.0	1.0	0.5
High cholesterol (Self-reported)	0.9	1.5	2.5	0.8	1.2	1.6	1.5	1.5	1.2	0.0	-1.5	1.4	1.3	1.2	1.3	1.4	1.1	1.2	0.7
Leg fat percentage (left)	0.9	3.3	7.6	-0.0	-1.3	-2.2	-2.1	-2.1	-1.6	2.8	2.2	-2.1	-1.6	-1.9	-1.7	-2.0	-1.1	-1.3	1.4
Blood Red Count	0.8	7.6	15.8	-4.0	-3.5	-2.5	-2.6	-2.8	-3.0	2.0	1.6	-2.6	-3.0	-2.4	-2.9	-2.4	-2.6	-3.3	-1.8
Hearing difficulty/problems: Yes	0.8	1.2	5.5	-0.7	-0.8	-2.3	-0.9	-0.8	-1.1	0.9	-0.0	-1.0	-1.0	-1.3	-1.2	-1.0	-1.1	-1.0	-0.3
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.0	1.1	0.9	-0.6	0.9	1.0	1.0	-0.6	-1.4	0.9	0.9	1.0	0.9	0.9	1.7	0.7	1.2
Leg fat percentage (right)	0.8	3.0	8.4	-0.1	-1.2	-2.0	-2.0	-2.0	-1.5	2.9	2.0	-2.0	-1.6	-1.8	-1.6	-1.9	-0.9	-1.2	1.7
Overall health rating	0.8	1.7	4.2	0.2	1.0	0.1	1.5	1.5	1.2	0.4	-2.0	1.4	1.2	2.0	1.4	2.1	1.0	1.3	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	8.1	-1.3	0.4	-0.3	1.3	1.1	0.8	-0.0	-1.7	1.3	0.8	1.7	1.0	1.6	1.5	0.5	2.8
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.9	-0.5	-0.9	-0.3	-1.0	-0.9	-1.0	1.1	0.3	-1.0	-1.0	-1.3	-1.1	-1.2	-1.7	-0.9	-0.2
Long-standing illness, disability or infirmity	0.8	1.3	1.7	0.9	0.9	0.5	1.2	1.1	1.2	-1.1	-1.2	1.2	1.1	1.3	1.3	1.3	1.2	1.2	1.1
Back pain experienced in last month	0.8	1.1	2.3	-1.5	-1.2	-1.2	-1.1	-1.1	-1.1	0.6	0.9	-1.1	-1.1	-0.8	-1.1	-1.0	-1.1	-1.2	0.2
Commuting to job workplace: Public transport	0.8	1.0	1.6	-0.7	-0.9	-0.9	-1.2	-1.1	-1.0	-0.9	1.1	-1.2	-1.1	-1.2	-1.0	-1.3	-0.4	-1.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	9.2	0.4	-0.2	-0.7	-0.6	-0.6	-0.5	3.0	1.7	-0.5	-0.3	-0.9	-0.4	-0.7	-0.1	-0.4	0.1
HDL Cholesterol	0.7	1.1	1.6	0.7	1.0	1.1	1.1	1.1	1.0	-0.4	-1.0	1.1	1.0	1.1	1.2	1.2	1.2	0.9	1.2
Forced vital capacity (FVC), Best measure	0.7	2.4	6.4	-2.5	-1.9	-2.1	-1.3	-1.1	-1.8	0.2	0.8	-1.4	-1.7	-1.4	-1.7	-1.7	-0.7	-1.9	0.8
Shortness of breath walking on level ground	0.7	0.9	2.9	-1.1	-0.7	-1.7	-0.6	-0.5	-0.8	1.7	-0.4	-0.6	-0.6	-0.8	-0.6	-0.9	-1.2	-0.6	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	4.5	0.3	0.6	-0.9	0.6	0.6	0.5	2.1	-1.4	0.7	0.6	0.5	0.8	0.7	0.6	0.5	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	3.7	-1.3	-0.9	-1.6	-1.0	-1.1	-0.9	1.9	1.9	-1.0	-1.0	-0.9	-1.2	-1.0	-0.8	-1.1	-0.4
Eye problems/disorders: Glaucoma	0.7	0.8	1.9	-1.1	-0.9	-1.4	-0.8	-0.7	-0.9	1.0	1.0	-0.7	-0.9	-0.7	-0.7	-0.8	-0.7	-1.0	-0.8
Crohns Disease (2017)	0.6	1.2	2.3	-0.7	-1.2	-1.1	-1.2	-1.1	-1.4	0.3	0.4	-1.3	-1.3	-1.5	-1.4	-1.3	-0.9	-1.3	-0.2
Lupus	0.6	1.0	4.1	0.4	0.7	-0.1	1.2	1.3	0.8	0.2	-2.0	1.1	0.8	1.0	0.9	0.8	0.6	0.9	-1.1
Primary Biliary Cirrhosis	0.6	0.9	4.2	1.6	0.9	0.9	0.7	0.9	0.8	-2.0	-1.0	0.6	0.7	0.2	0.9	0.2	0.1	0.8	0.5
Blood Eosinophil Count	0.6	4.8	14.5	-0.1	-1.7	-1.9	-2.6	-2.6	-2.0	1.8	3.8	-2.6	-2.1	-2.1	-2.4	-2.1	-2.3	-1.5	0.6
Height	0.6	12.5	48.4	-7.0	-4.5	-4.2	-2.7	-2.4	-4.3	-0.6	0.2	-2.9	-3.9	-3.2	-3.8	-3.4	-1.9	-4.3	0.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.7	0.2	0.6	-0.8	1.0	1.0	0.7	0.4	-1.3	1.0	0.8	1.2	1.0	1.3	0.6	0.8	0.5
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.1	1.0	1.1	0.4	0.9	0.9	1.1	-1.0	-0.7	0.9	1.0	0.9	0.9	0.8	0.9	1.0	-0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	5.0	-0.0	0.5	-0.7	0.5	0.3	0.8	-0.4	0.1	0.6	0.6	0.7	0.6	0.8	1.2	0.6	2.2
High blood pressure (mother)	0.6	0.9	2.0	0.4	0.9	0.9	1.0	1.0	1.0	0.3	-0.9	1.0	1.0	1.3	1.0	1.2	1.4	0.9	0.1
Qualifications: None of the above	0.6	1.3	6.3	-1.1	-0.8	-1.2	-1.0	-0.8	-1.1	2.5	1.2	-1.0	-0.9	-1.0	-1.2	-1.1	-1.1	-1.0	-0.2
Standing height	0.6	6.1	26.7	-5.2	-3.2	-2.6	-1.8	-1.7	-3.0	0.3	0.2	-2.0	-2.7	-2.1	-2.6	-2.2	-0.8	-3.1	1.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.3	-0.7	-1.2	-0.2	-1.0	-1.0	-0.9	-0.3	1.1	-0.9	-1.0	-0.8	-0.8	-0.7	-1.1	-1.0	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.7	0.7	0.8	1.3	0.7	0.6	0.9	1.6	0.3	0.8	0.8	0.7	1.0	0.9	0.6	0.8	0.6
Leg pain on walking	0.6	0.8	1.1	0.9	1.0	-0.2	1.0	0.8	1.0	-0.9	-0.9	1.0	1.0	1.0	1.0	1.0	0.6	0.8	-0.4
Commuting to job workplace: Car/motor vehicle	0.6	0.6	4.7	0.2	-0.5	-0.8	-0.7	-0.8	-0.6	2.2	1.0	-0.6	-0.4	-0.6	-0.6	-0.5	-0.1	-0.3	0.7
Loneliness, isolation	0.6	0.8	1.7	0.9	0.8	0.3	1.0	1.0	1.0	0.3	-0.9	0.9	0.9	0.8	1.0	0.9	0.6	0.9	1.3
Mineral and other dietary supplements	0.6	0.8	2.6	-1.0	-1.2	-1.6	-0.8	-0.7	-1.0	-0.5	0.0	-0.9	-1.1	-0.7	-1.0	-0.7	0.3	-1.0	0.4
Illnesses of father: None of the above (group 1)	0.6	0.8	2.7	-0.7	-0.8	0.2	-0.8	-0.6	-0.9	-0.1	0.6	-0.9	-0.9	-1.2	-0.9	-1.3	-1.6	-0.6	-0.4
Medication: Lisinopril	0.6	0.7	2.5	0.9	0.6	1.3	0.7	0.6	0.8	-0.8	-1.0	0.8	0.8	0.7	0.7	0.8	0.3	0.7	-1.6
Age started oral contraceptive pill	0.6	0.8	3.2	1.8	1.1	0.7	0.5	0.5	1.1	-0.8	-0.0	0.5	0.9	0.6	0.8	0.4	0.5	1.1	1.2
Commuting to job workplace: Cycle	0.6	0.7	2.3	0.8	0.8	0.6	0.9	0.9	0.9	-1.5	-1.1	0.8	0.8	0.7	0.8	0.7	1.0	0.7	0.2
Myopia	0.6	0.8	2.4	-0.8	-0.9	0.5	-1.0	-0.9	-1.0	0.1	1.6	-1.0	-1.0	-1.1	-0.9	-0.9	-0.4	-1.1	0.3
Pack years of smoking	0.6	0.9	2.4	-0.9	-1.0	-0.6	-0.8	-0.7	-0.9	-1.1	0.1	-0.9	-1.0	-0.7	-1.0	-0.8	-1.0	-0.8	-1.6
Respiratory disease	0.5	1.1	5.4	-1.6	-1.1	-2.3	-0.5	-0.7	-0.9	1.9	-0.4	-0.5	-0.8	-0.4	-0.6	-0.4	-0.9	-1.0	0.5
Pack years adult smoking proportion	0.5	0.8	2.6	-1.1	-1.1	-0.6	-0.8	-0.6	-1.0	-1.0	-0.1	-0.8	-1.0	-0.7	-0.9	-0.7	-0.8	-0.8	-1.6
Current tobacco smoking	0.5	0.9	2.3	-0.3	0.5	0.4	1.1	1.1	0.7	-0.9	-1.5	1.1	0.7	1.1	0.9	1.2	0.3	0.4	-1.5
Relative age voice broke	0.5	0.8	2.6	1.6	1.0	1.0	0.4	0.3	0.8	0.9	1.3	0.5	0.8	0.6	0.7	0.7	-0.0	1.0	1.3
Chronic bronchitis/emphysema (father)	0.5	0.6	1.1	-0.6	-0.7	-1.0	-1.0	-1.1	-0.7	-0.3	0.7	-0.9	-0.8	-0.7	-0.8	-0.7	-0.4	-0.9	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.4	-1.6	-1.2	-0.8	-0.8	-0.8	-1.0	-0.2	0.5	-0.9	-1.1	-0.7	-0.8	-0.6	-1.1	-1.0	-0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.6	1.2	1.1	1.0	0.7	0.5	1.0	-1.3	-0.2	0.8	1.0	1.0	1.1	1.2	1.3	1.3	1.9
Impedance of arm (left)	0.5	2.3	4.3	1.9	1.8	1.1	1.6	1.7	1.7	0.1	-1.1	1.6	1.8	1.0	1.4	1.3	1.4	1.8	2.1
Birth weight of first child	0.5	0.9	2.5	-1.6	-1.4	-0.7	-0.7	-0.6	-1.3	-0.7	-1.0	-0.7	-1.1	-0.8	-1.1	-1.1	-0.1	-1.1	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	3.8	0.2	-0.3	-0.8	-0.7	-0.7	-0.4	1.9	1.2	-0.6	-0.4	-0.5	-0.6	-0.7	-0.5	-0.3	0.1
Medication: Omeprazole	0.5	0.5	4.3	0.3	-0.2	-0.5	-0.5	-0.6	-0.4	2.1	1.3	-0.5	-0.3	-0.7	-0.4	-0.5	-0.4	-0.3	-0.3
Alcohol intake frequency.	0.5	1.2	4.8	-0.7	-0.8	-1.3	-1.1	-1.2	-0.9	1.1	1.4	-1.0	-0.9	-1.0	-0.8	-0.8	-0.2	-1.0	2.2
Mood swings	0.5	0.9	5.0	0.2	0.6	-0.1	0.8	0.6	0.7	2.2	-0.4	0.8	0.8	0.9	0.8	1.1	1.0	0.9	1.4
Eye problems/disorders: Cataract	0.5	0.6	1.5	0.7	0.6	0.7	0.8	0.9	0.7	-0.6	-1.2	0.7	0.7	0.8	0.7	0.6	0.8	0.7	0.7
Ever taken oral contraceptive pill	0.5	0.6	1.7	0.6	-0.4	-0.3	-0.8	-0.7	-0.6	0.3	1.0	-0.9	-0.6	-1.3	-1.0	-1.1	-0.9	-0.5	-0.6
Financial situation satisfaction	0.5	0.7	2.2	-0.5	-0.8	-0.9	-0.8	-0.7	-0.8	-1.5	0.3	-0.8	-0.8	-1.0	-0.8	-0.8	-0.6	-0.9	0.4
Medication: Atorvastatin	0.5	0.6	2.0	-0.1	0.3	0.7	0.8	0.8	0.4	0.8	-1.4	0.8	0.5	1.0	0.6	0.9	1.1	0.5	0.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	5.3	-0.0	-0.2	-0.3	-0.7	-0.7	-0.3	1.0	1.2	-0.6	-0.4	-0.2	-0.2	-0.3	-0.1	-0.2	2.3
Schizophrenia (2014)	0.4	1.0	2.5	0.8	1.1	1.0	1.0	1.0	1.0	0.2	-0.8	1.0	1.1	0.8	0.8	0.9	1.6	1.0	1.1
Ulcerative Colitis	0.4	0.5	2.3	0.8	0.5	1.2	0.4	0.4	0.3	-1.5	-0.4	0.2	0.4	0.4	0.6	0.4	1.0	0.7	0.9
Hypothyroidism (self reported)	0.4	1.0	1.7	-0.8	-1.0	-1.3	-1.1	-0.9	-1.1	-0.1	0.9	-1.1	-1.2	-1.1	-1.0	-1.1	-1.1	-1.0	-0.8
Lung FEV1/FVC ratio	0.4	2.2	4.2	0.5	1.4	0.7	1.8	1.9	1.5	1.6	-2.0	1.8	1.6	1.7	1.5	1.7	0.8	1.5	-0.7
Diabetes (father)	0.4	0.5	4.1	0.2	0.2	-0.9	-0.1	-0.1	0.0	1.2	0.7	-0.0	0.1	-0.1	-0.1	0.2	0.3	0.1	2.0
Townsend deprivation index at recruitment	0.4	0.5	1.8	0.6	0.7	-0.2	0.5	0.6	0.5	1.3	-0.2	0.6	0.5	0.6	0.5	0.7	1.3	0.5	1.1
Alcohol usually taken with meals	0.4	0.6	3.4	1.9	0.9	1.1	0.4	0.3	0.8	-1.3	-0.1	0.4	0.7	0.3	0.5	0.5	-0.1	0.8	-0.1
Forced vital capacity (FVC)	0.4	1.4	5.5	-2.3	-1.4	-1.7	-0.8	-0.7	-1.3	0.0	0.2	-0.9	-1.2	-1.0	-1.2	-1.2	-0.2	-1.5	0.5
Falls in the last year	0.4	0.5	1.7	0.3	0.3	0.9	0.9	1.0	0.5	-0.4	-1.3	0.9	0.6	0.7	0.8	0.6	0.3	0.4	-0.8
Exposure to tobacco smoke at home	0.4	0.4	1.7	0.6	-0.1	-0.3	-0.6	-0.4	-0.4	0.1	0.8	-0.6	-0.4	-0.7	-0.3	-0.7	1.0	-0.3	1.3
Blood clot in the leg (DVT)	0.4	0.5	4.6	-0.2	-0.3	-0.2	-0.5	-0.6	-0.3	0.8	0.8	-0.5	-0.4	-0.1	-0.1	-0.2	0.1	-0.3	2.2
Gout (self-reported)	0.4	0.5	3.1	-1.8	-0.8	-0.2	-0.1	-0.0	-0.6	0.4	-1.1	-0.1	-0.5	-0.3	-0.7	-0.3	-0.2	-0.8	-1.1
Medication: Ventolin 100micrograms inhaler	0.4	0.6	2.4	-0.3	-1.0	-0.7	-0.6	-0.6	-0.9	-0.0	0.0	-0.6	-0.8	-0.8	-0.7	-0.9	-0.2	-0.8	1.6
Birth weight	0.4	1.0	2.5	0.2	0.4	0.6	1.1	1.2	0.5	-1.0	-1.6	1.0	0.7	1.2	0.8	0.9	1.5	1.0	1.1
Number of children fathered	0.4	0.5	3.5	-0.8	-0.4	-1.1	-0.3	-0.5	-0.5	1.9	0.3	-0.3	-0.4	-0.1	-0.3	-0.1	-0.4	-0.5	-0.7
Comparative height size at age 10	0.4	2.3	13.3	-3.7	-2.2	-1.4	-0.8	-0.5	-2.0	0.0	-0.6	-0.9	-1.7	-0.8	-1.6	-1.0	-0.4	-2.0	0.3
Commuting to job workplace: Walk	0.4	0.4	3.7	-0.5	-0.3	-0.5	-0.1	0.0	-0.2	-1.9	-0.6	-0.2	-0.3	-0.2	-0.2	-0.3	0.2	-0.2	-1.1
Osteoporosis (self-reported)	0.4	0.5	2.9	0.9	0.5	0.1	0.3	0.4	0.4	1.7	0.2	0.3	0.4	0.3	0.4	0.3	0.4	0.5	1.5
Smoking status: Current	0.4	0.6	2.3	-0.4	0.3	0.1	0.8	0.8	0.5	-1.0	-1.2	0.8	0.4	0.8	0.6	0.9	0.1	0.2	-1.5
Average weekly champagne plus white wine intake	0.4	0.6	6.0	0.3	0.2	0.8	0.2	0.3	0.3	-2.5	-0.5	0.2	0.2	-0.1	-0.1	0.1	-0.6	0.1	-1.2
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.9	-0.3	0.6	1.4	0.7	0.5	0.8	0.0	-0.2	0.8	0.8	0.8	0.6	0.7	-0.4	0.5	-1.0
Depressed Affect (Nagel 2018)	0.3	0.6	1.3	0.2	0.6	0.2	0.9	0.8	0.8	0.8	-0.7	0.9	0.8	1.0	1.0	1.1	1.0	0.8	0.0
Major Depression (MDD)	0.3	0.3	4.6	0.3	-0.0	-0.3	0.0	-0.1	-0.0	0.2	0.3	0.0	0.0	0.1	-0.2	0.2	0.7	-0.1	2.1
Reaction Time	0.3	0.5	5.3	0.1	-0.4	0.2	-0.3	-0.2	-0.2	-2.3	-0.1	-0.3	-0.4	-0.2	-0.2	-0.2	-0.1	-0.2	1.3
Smoking Status	0.3	0.8	4.2	-0.1	0.3	0.4	0.9	1.0	0.5	-0.7	-1.9	0.9	0.5	0.7	0.7	0.7	0.1	0.1	-2.0
Hand grip strength (left)	0.3	0.7	4.1	-0.9	0.2	-0.5	1.0	1.1	0.4	-0.1	-2.0	1.0	0.5	0.8	0.6	0.7	0.4	0.2	0.6
Vitamin and mineral supplements	0.3	0.3	2.2	0.8	0.2	1.2	0.1	0.2	0.2	-1.5	-0.2	0.1	0.1	-0.0	0.0	0.0	0.7	0.1	0.8
Hand grip strength (right)	0.3	0.7	3.3	-0.5	0.5	-0.1	1.1	1.2	0.6	-0.3	-1.8	1.2	0.7	1.0	0.9	1.0	0.1	0.4	0.3
Average weekly fortified wine intake	0.3	0.3	1.5	0.7	0.6	1.1	-0.1	-0.2	0.4	0.2	1.2	-0.1	0.3	0.0	0.3	0.1	-1.0	0.4	-0.1
Maternal smoking around birth	0.3	0.4	2.2	0.2	-0.3	0.4	-0.5	-0.5	-0.4	0.3	0.8	-0.5	-0.5	-0.7	-0.5	-0.7	-0.9	-0.5	-1.5
Stomach or abdominal pain in last month	0.3	0.4	1.0	0.0	-0.3	-0.9	-0.7	-0.8	-0.5	0.8	1.0	-0.7	-0.4	-0.7	-0.3	-0.6	-0.3	-0.4	-0.2
Illnesses of siblings	0.3	0.5	3.3	-0.2	-0.1	0.5	-0.1	-0.0	-0.0	-1.8	-0.2	-0.1	-0.1	-0.4	-0.2	-0.1	-0.3	-0.2	-1.8
Impedance of arm (right)	0.3	1.3	4.5	1.6	1.4	0.9	1.0	1.1	1.1	0.4	-0.5	1.0	1.2	0.5	0.9	0.7	0.8	1.4	2.1
Wheeze or whistling in the chest in last year	0.3	0.6	1.6	0.4	0.5	-0.3	0.8	0.6	0.7	0.5	-0.8	0.9	0.7	1.0	0.8	1.0	0.4	0.5	1.3
Age at first live birth	0.3	0.6	2.2	0.6	0.5	-0.1	0.6	0.8	0.3	-0.5	-1.2	0.6	0.5	0.3	0.7	0.2	1.5	0.6	1.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.8	-1.0	-0.2	-0.3	0.6	0.5	0.1	1.0	-1.4	0.6	0.1	0.8	0.3	0.8	-0.1	-0.1	-0.6
Medication: Ibuprofen	0.3	0.4	0.8	0.5	0.7	0.3	0.8	0.9	0.7	-0.3	-0.7	0.7	0.7	0.3	0.5	0.4	0.7	0.7	0.4
Medication: Seretide 50 evohaler	0.3	0.3	1.8	-0.7	-0.7	-1.1	-0.1	0.0	-0.7	0.4	-1.4	-0.1	-0.5	-0.1	-0.3	-0.1	-0.1	-0.4	0.3
Number of full sisters	0.3	0.3	1.2	0.9	0.5	1.1	0.6	0.7	0.4	-0.7	-0.3	0.6	0.5	0.5	0.4	0.4	0.6	0.3	-0.6
Chest pain or discomfort	0.3	0.4	2.8	-1.0	-0.3	0.2	0.4	0.3	0.1	-0.5	-1.1	0.5	0.1	0.4	0.3	0.4	0.1	-0.2	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.2	0.1	0.5	0.3	0.6	0.4	0.4	1.1	-0.3	0.6	0.6	0.9	0.8	0.9	0.5	0.6	0.7
Smoking status: Previous	0.3	0.5	1.3	0.8	0.6	0.7	0.8	0.8	0.6	-0.4	-1.1	0.8	0.7	0.6	0.9	0.6	0.6	0.6	-0.1
Ever had bowel cancer screening	0.3	0.4	4.4	-0.5	0.2	-0.3	0.3	0.1	0.1	2.1	-0.6	0.3	0.2	0.5	0.2	0.5	-0.1	0.2	0.7
Friendships satisfaction	0.3	0.4	1.1	0.8	0.6	0.7	0.5	0.4	0.8	-1.1	-0.1	0.6	0.6	0.5	0.6	0.5	0.1	0.6	-0.6
Qualifications: nursing, teaching	0.3	0.4	3.4	0.6	0.2	0.9	0.1	0.1	0.4	-1.8	-0.1	0.2	0.2	0.4	0.4	0.4	0.6	0.2	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	5.1	0.0	0.2	0.1	0.1	0.1	-0.0	2.3	0.5	0.1	0.2	-0.1	0.1	-0.1	0.8	0.3	-0.3
Unable to work because of sickness or disability	0.3	0.3	4.1	-0.4	0.1	-0.6	0.0	-0.1	-0.1	2.0	-0.0	0.0	0.1	0.4	0.1	0.5	0.2	0.1	0.3
Pain experienced in last month	0.3	0.5	0.8	-0.7	-0.9	-0.6	-0.7	-0.5	-0.9	0.8	0.1	-0.7	-0.9	-0.6	-0.7	-0.7	0.1	-0.9	0.4
Alcohol drinker status: Previous	0.3	0.4	2.0	-0.7	-0.4	-0.9	-0.5	-0.5	-0.6	-0.6	-0.2	-0.5	-0.5	-0.7	-0.3	-0.4	-0.3	-0.3	1.4
Schizophrenia (2018)	0.2	0.4	2.5	0.3	0.8	0.9	0.5	0.4	0.6	1.6	-0.1	0.6	0.8	0.3	0.4	0.3	0.6	0.5	-0.2
Alzheimer’s Disease (including proxy)	0.2	0.3	1.6	-0.2	0.2	-0.5	0.3	0.2	0.3	1.0	0.1	0.4	0.3	0.5	0.5	0.5	1.3	0.3	0.9
Prostate Cancer	0.2	0.3	0.8	-0.1	-0.5	0.1	-0.5	-0.3	-0.6	-0.4	0.1	-0.5	-0.6	-0.8	-0.5	-0.5	0.0	-0.5	0.9
Rheumatoid Arthritis	0.2	0.3	1.7	-0.8	-0.2	-1.2	-0.2	-0.1	-0.4	1.3	-0.2	-0.2	-0.2	-0.4	-0.2	-0.5	-0.3	-0.3	-0.6
Average weekly spirits intake	0.2	0.2	1.6	0.8	0.4	0.3	0.1	0.4	-0.0	1.2	-0.3	0.0	0.2	-0.2	0.3	-0.3	0.2	0.4	0.9
Systolic blood pressure, automated reading	0.2	0.7	2.4	-0.3	0.3	0.6	0.8	0.7	0.7	-0.5	-1.5	0.9	0.5	1.1	0.8	0.8	1.6	0.1	0.8
Diabetes (mother)	0.2	0.3	2.2	1.0	0.4	-0.1	-0.3	-0.3	0.2	0.8	1.5	-0.3	0.1	0.2	-0.1	0.1	-0.2	0.4	0.0
Taking other prescription medications	0.2	0.3	2.3	0.5	0.5	0.3	0.3	0.2	0.5	1.5	0.5	0.3	0.5	0.3	0.4	0.4	-0.4	0.5	0.2
Multivitamins +/- minerals	0.2	0.3	2.7	-0.6	-0.0	-0.7	-0.1	-0.3	-0.0	1.6	0.7	0.0	0.1	0.2	0.1	0.3	-0.5	0.0	0.1
Supplements: Glucosamine	0.2	0.3	1.1	1.1	0.6	0.3	0.2	0.2	0.5	-0.9	-0.0	0.2	0.4	-0.1	0.5	0.1	-0.4	0.3	-0.9
Sitting height	0.2	1.6	9.1	-3.0	-1.7	-0.7	-0.7	-0.7	-1.3	-1.6	-0.3	-0.7	-1.3	-0.8	-1.2	-0.8	-0.3	-1.6	-0.3
Number of incorrect matches in round	0.2	0.3	2.3	-0.6	-0.4	-0.5	-0.3	-0.2	-0.3	-0.4	-0.1	-0.3	-0.4	-0.1	-0.5	-0.2	-0.6	-0.5	-1.5
Financial difficulties in last 2 years	0.2	0.2	1.4	-0.3	-0.4	-0.1	-0.1	0.0	-0.3	-1.1	-0.6	-0.1	-0.3	0.0	-0.0	-0.1	0.2	-0.3	1.2
Allergy	0.2	0.4	1.4	1.0	0.8	1.2	0.3	0.4	0.5	-0.8	0.2	0.2	0.5	0.2	0.2	0.2	0.5	0.9	0.3
Father’s age at death	0.2	0.2	1.5	0.3	0.1	-1.2	-0.2	-0.1	-0.1	0.9	-0.1	-0.2	-0.1	-0.2	-0.1	-0.1	-0.4	-0.0	1.2
Hair/balding pattern: Pattern 3	0.2	0.3	3.1	-0.4	0.0	0.7	0.2	0.3	-0.1	1.8	-0.7	0.2	0.0	0.1	0.3	-0.0	0.2	-0.0	0.3
Noisy workplace	0.2	0.3	1.4	0.9	0.6	0.3	0.5	0.6	0.4	0.4	-0.7	0.4	0.4	0.1	0.3	0.2	0.3	0.4	1.2
Medication: Cholesterol lowering	0.2	0.2	1.0	-1.0	-0.4	-0.9	0.2	0.1	-0.2	0.3	-0.6	0.2	-0.1	0.4	-0.2	0.3	0.9	-0.4	-0.3
Medication: Lansoprazole	0.2	0.2	0.7	-0.5	-0.4	-0.5	-0.5	-0.5	-0.5	0.8	0.2	-0.5	-0.5	-0.2	-0.5	-0.2	-0.8	-0.2	-0.1
Lung cancer (father)	0.2	0.3	0.6	-0.4	-0.6	0.1	-0.6	-0.5	-0.7	0.1	0.2	-0.6	-0.6	-0.8	-0.6	-0.8	-0.4	-0.5	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.5	-1.6	-0.8	-1.1	-0.4	-0.2	-0.7	0.1	0.3	-0.5	-0.7	-0.4	-0.7	-0.6	-0.1	-0.8	1.1
Length of working week for main job	0.2	0.2	2.1	-0.1	-0.1	-0.7	0.0	0.0	0.2	-1.5	-0.1	0.0	-0.0	0.4	-0.1	0.2	0.1	0.0	0.7
Medication: Paracetamol	0.2	0.3	2.1	0.6	0.4	0.0	0.4	0.4	0.5	-1.5	-0.4	0.4	0.4	0.3	0.2	0.4	0.0	0.6	0.4
Headache pain in last month	0.2	0.3	1.6	1.3	0.5	0.6	-0.1	-0.2	0.4	-0.9	0.9	-0.0	0.3	-0.0	0.1	0.0	-0.3	0.3	-0.1
Exposure to tobacco smoke outside home	0.2	0.3	1.6	1.2	0.5	0.3	0.3	0.4	0.4	-0.9	-0.3	0.3	0.4	0.0	0.4	0.1	0.4	0.5	0.8
Comparative body size at age 10	0.2	0.5	1.9	0.0	-0.7	-0.3	-0.8	-0.8	-0.5	-0.6	1.4	-0.7	-0.7	-0.4	-0.5	-0.3	-0.7	-0.7	1.2
Migraine (self-reported)	0.2	0.3	2.3	-0.1	-0.1	0.1	-0.4	-0.6	-0.1	-0.3	1.5	-0.3	-0.1	-0.3	-0.3	0.0	-0.9	-0.1	0.8
Mean time to correctly identify matches	0.2	0.3	3.0	0.5	-0.1	-0.4	-0.2	-0.2	-0.0	-1.7	0.0	-0.2	-0.2	-0.2	-0.1	-0.2	-0.0	-0.1	1.2
Supplements: Vitamin C	0.2	0.2	1.0	-0.7	-0.2	-0.6	0.3	0.4	-0.0	0.5	-1.0	0.3	-0.0	0.6	0.2	0.2	-0.3	-0.1	-0.7
Medication: Paracetamol	0.2	0.3	1.0	0.7	0.5	-0.2	0.6	0.7	0.5	-0.8	-1.0	0.6	0.6	0.3	0.4	0.4	0.5	0.7	0.2
Number of operations (self-reported)	0.2	0.3	2.1	-0.3	-0.3	-0.9	-0.4	-0.5	-0.4	1.5	0.1	-0.3	-0.3	-0.4	-0.2	-0.4	-0.5	-0.3	-0.1
Heart disease (siblings)	0.2	0.3	2.3	-0.8	-0.6	-1.5	-0.1	-0.0	-0.4	0.0	-0.0	-0.2	-0.4	-0.0	-0.3	-0.3	0.7	-0.4	0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.8	-0.1	-0.6	-0.7	-0.7	-0.6	-0.8	-0.1	0.0	-0.7	-0.7	-0.9	-0.7	-0.7	0.1	-0.6	0.4
Ulcerative Colitis (UC)	0.1	0.1	0.2	0.2	-0.3	-0.2	-0.4	-0.5	-0.3	-0.4	0.3	-0.5	-0.3	-0.4	-0.3	-0.3	0.4	-0.1	0.4
Breast Cancer	0.1	0.2	0.6	-0.3	-0.3	-0.8	-0.4	-0.3	-0.2	-0.1	0.7	-0.4	-0.3	-0.3	-0.3	-0.2	-0.5	-0.3	0.3
Crohns Disease (2012)	0.1	0.2	0.7	0.1	-0.3	-0.2	-0.5	-0.5	-0.6	0.1	0.4	-0.5	-0.4	-0.8	-0.5	-0.4	0.0	-0.4	0.6
LDL Cholesterol	0.1	0.2	2.6	-0.0	0.0	0.4	0.3	0.3	0.1	1.6	-0.1	0.3	0.2	0.0	0.1	0.0	0.0	0.2	-0.3
Allergy or Eczema	0.1	0.3	2.1	-0.6	-0.4	-0.9	-0.1	-0.2	-0.3	1.4	0.1	-0.1	-0.3	-0.1	0.0	-0.1	-0.4	-0.5	0.4
Lung FVC	0.1	0.5	2.2	1.2	0.7	0.1	0.4	0.5	0.7	-1.5	0.1	0.3	0.5	0.3	0.3	0.0	1.3	0.4	-0.0
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.4	-0.3	-0.2	-0.4	0.0	0.1	0.0	-0.5	-0.6	-0.0	-0.1	0.4	0.0	0.1	-0.1	0.0	-0.2
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	-0.2	-0.3	-0.2	-0.3	-0.4	-0.3	0.4	0.5	-0.2	-0.3	-0.2	-0.2	-0.2	-0.4	-0.3	-0.5
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.9	-0.1	0.3	0.1	0.7	0.6	0.5	0.2	-0.9	0.8	0.5	0.7	0.8	0.6	0.4	0.1	0.1
Had menopause	0.1	0.1	0.5	-0.1	-0.1	-0.7	-0.2	-0.4	-0.1	0.1	-0.4	-0.1	-0.1	-0.0	0.0	-0.0	-0.5	-0.2	-0.1
Mouth/teeth dental problems	0.1	0.2	0.7	0.2	0.4	0.5	0.2	0.3	0.3	-0.8	0.3	0.1	0.2	0.5	0.3	0.4	-0.6	0.4	0.8
Medication: Simvastatin	0.1	0.1	0.6	-0.1	-0.1	-0.2	-0.0	-0.1	-0.0	-0.8	0.1	0.0	-0.0	-0.2	-0.2	-0.2	-0.3	-0.2	-0.7
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	2.4	-1.5	-0.5	-0.6	0.1	0.2	-0.3	-0.3	-0.1	0.0	-0.3	-0.0	-0.3	-0.1	0.5	-0.6	1.0
Prospective memory result	0.1	0.1	0.7	0.2	0.2	0.8	0.4	0.5	0.2	0.1	-0.6	0.3	0.2	0.5	0.4	0.2	0.3	0.4	0.1
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	-0.7	-0.1	-0.1	-0.1	-0.1	-0.3	0.6	-0.1	-0.1	-0.2	-0.2	-0.0	-0.3	0.5	-0.2	-0.0
Breastfed as a baby	0.1	0.2	0.9	-0.2	-0.0	-0.5	-0.2	-0.4	0.2	-0.9	0.5	-0.1	0.0	0.2	-0.1	0.3	0.5	-0.2	1.0
Number of full brothers	0.1	0.1	1.3	0.1	0.1	-0.1	0.4	0.5	0.2	-0.4	-1.1	0.3	0.1	0.1	0.3	0.1	0.4	-0.0	0.0
Eye problems/disorders: None of the above	0.1	0.1	0.5	0.1	-0.0	-0.1	-0.3	-0.4	-0.1	0.5	0.7	-0.2	-0.1	-0.4	-0.1	-0.2	-0.0	-0.3	0.6
Neck or shoulder pain in last month	0.1	0.1	0.8	-0.2	0.1	-0.1	-0.2	-0.4	0.1	0.1	0.9	-0.2	0.1	-0.0	-0.2	0.1	0.1	0.1	0.9
Knee pain experienced in last month	0.1	0.1	1.3	0.3	-0.1	-1.1	-0.3	-0.3	-0.1	-0.2	0.3	-0.3	-0.2	-0.4	-0.1	-0.4	-0.3	-0.1	0.2
Alcohol drinker status: Never	0.1	0.1	0.8	0.1	0.2	0.9	0.1	0.2	0.2	0.4	0.2	0.2	0.2	0.1	0.3	0.1	-0.2	0.1	0.2
Hair Pigment	0.0	0.3	2.2	0.2	0.3	0.0	-0.0	-0.0	0.1	1.5	0.2	0.0	0.2	-0.2	-0.1	0.0	-0.9	0.2	-0.9
Tanning	0.0	0.4	0.9	0.4	0.4	0.9	0.8	0.8	0.6	0.1	-0.8	0.8	0.6	0.6	0.5	0.5	0.5	0.4	-0.5
Age when periods started (menarche)	0.0	0.1	0.3	0.6	0.3	-0.2	-0.3	-0.2	0.1	0.0	0.5	-0.3	0.0	-0.4	-0.1	-0.3	-0.5	0.1	-0.3
Happiness	0.0	0.0	0.3	-0.5	-0.1	0.0	0.1	0.1	0.0	0.4	0.1	0.2	0.1	0.1	0.1	0.4	-0.1	-0.2	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.1	-0.0	0.1	0.0	0.2	0.3	0.2	0.1	-0.0	0.2	0.2	-0.1	0.0	-0.1	0.3	0.2	0.2
Pulse wave peak to peak time	0.0	0.1	0.5	0.3	-0.1	0.0	-0.0	0.0	0.1	-0.7	0.2	-0.0	-0.0	-0.0	-0.1	0.2	-0.4	0.0	0.1
Pulse rate, automated reading	0.0	0.2	1.1	-0.2	-0.4	-0.3	-0.3	-0.3	-0.3	1.0	0.5	-0.3	-0.4	-0.3	-0.3	-0.1	-0.2	-0.3	-0.1
Age at last live birth	0.0	0.1	0.4	-0.2	-0.0	-0.1	0.1	0.2	-0.2	-0.4	-0.6	0.1	-0.0	-0.1	0.0	0.1	0.4	0.0	0.3
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.2	-0.4	-0.4	0.2	-0.0	-0.2	-0.1	0.0	-0.0	0.0	-0.1	-0.1	-0.2	0.2	-0.1	-0.2	0.3

Hub : Genes

TPM2

Models

Trait associations