[Hub]/) : Traits : Whole body fat-free mass : ← →

chr9:97,520,168-100,366,953

Best TWAS P=5.09e-23 · Best GWAS P=6.53e-27 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Tibial	RP11-435O5.5	0.09	0.04	lasso	2	0.02	7.3e-03	10.1	-9.9	5.1e-23	-0.95	0.02	0.94	TRUE
24	The Cancer Genome Atlas	Stomach Adenocarcinoma	CDC14B	0.08	0.02	blup	41	0.04	1.0e-03	6.0	-8.7	4.2e-18	-0.08	0.02	0.60	TRUE
13	NTR	Blood	PTCH1	0.04	0.02	blup	433	0.02	4.1e-08	7.1	6.0	1.8e-09	0.09	0.98	0.00	TRUE
5	GTEx	Cells Transformed fibroblasts	RP11-435O5.5	0.14	0.04	lasso	4	0.02	7.9e-03	5.2	-5.4	6.2e-08	-0.60	0.36	0.03	TRUE
10	GTEx	Spleen	PTCH1	0.33	0.08	lasso	8	0.18	1.9e-05	-0.1	5.4	7.9e-08	0.28	0.17	0.10	TRUE
6	GTEx	Heart Atrial Appendage	RP11-435O5.4	0.18	0.00	lasso	5	0.00	6.2e-01	2.7	-5.3	1.0e-07	-0.10	0.04	0.43	TRUE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	PTCH1	0.02	0.01	blup	54	0.02	1.1e-03	8.7	-8.7	4.9e-18	-0.86	0.02	0.73	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	HABP4	0.08	0.06	blup	44	0.05	1.6e-02	7.8	-8.5	1.3e-17	-0.06	0.03	0.49	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HABP4	0.02	0.02	blup	44	0.02	7.1e-03	8.2	8.5	2.4e-17	0.04	0.03	0.68	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC14B	0.02	0.01	lasso	1	0.01	3.0e-03	8.4	-8.4	3.7e-17	-0.04	0.02	0.61	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC14B	0.03	0.02	blup	42	0.02	2.1e-03	8.2	-8.4	4.6e-17	-0.04	0.03	0.67	FALSE
11	GTEx	Testis	HABP4	0.19	0.22	lasso	9	0.21	1.1e-09	8.3	8.3	1.3e-16	0.04	0.06	0.94	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	CDC14B	0.05	0.07	blup	42	0.08	4.8e-08	8.3	-8.2	2.6e-16	-0.03	0.04	0.96	FALSE
12	GTEx	Thyroid	CDC14B	0.15	0.10	lasso	5	0.08	5.3e-07	7.9	-8.0	1.4e-15	-0.04	0.22	0.78	FALSE
14	YFS	Blood	HABP4	0.08	0.09	enet	24	0.11	5.9e-34	8.3	-8.0	1.6e-15	-0.09	0.04	0.96	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	HABP4	0.05	0.08	lasso	5	0.08	6.9e-09	7.8	-7.9	1.9e-15	-0.05	0.09	0.91	FALSE
15	YFS	Blood	PTCH1	0.09	0.05	lasso	8	0.05	1.2e-15	7.1	7.9	3.7e-15	0.42	1.00	0.00	FALSE
9	GTEx	Nerve Tibial	ZNF367	0.10	0.05	lasso	3	0.02	7.9e-03	8.5	7.7	1.2e-14	0.04	0.02	0.97	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	CDC14B	0.05	0.06	lasso	5	0.06	6.5e-07	8.2	-7.6	3.5e-14	-0.04	0.06	0.94	FALSE
17	The Cancer Genome Atlas	Glioblastoma Multiforme	CDC14B	0.16	0.17	blup	41	0.19	2.6e-06	8.2	-7.4	9.4e-14	-0.01	0.04	0.93	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	AAED1	0.17	0.02	lasso	3	0.04	2.4e-02	8.2	7.3	3.1e-13	0.02	0.04	0.52	FALSE
3	GTEx	Breast Mammary Tissue	CDC14B	0.16	0.02	enet	21	0.02	3.7e-02	8.2	-7.1	1.8e-12	-0.02	0.06	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LOC441454	0.05	0.01	lasso	3	0.02	1.5e-03	6.0	6.7	2.4e-11	0.04	0.04	0.57	FALSE
7	GTEx	Liver	PTCH1	0.25	0.06	enet	11	0.03	4.9e-02	9.7	6.3	3.6e-10	0.26	0.16	0.06	FALSE
8	GTEx	Nerve Tibial	HSD17B3	0.14	0.00	enet	20	0.00	2.4e-01	7.9	6.1	8.6e-10	0.05	0.08	0.44	FALSE