TWAS
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Usage
Models
Genes
Traits
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Traits
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Whole body fat-free mass
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chr10:95,019,584-97,070,115
Best TWAS P=1.39e-08 · Best GWAS P=4.22e-14 conditioned to 4.3e-08
95M
95.5M
96M
96.5M
97M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
TBC1D12
0.04
0.04
blup
63
0.03
3.9e-04
4.9
5.7
1.4e-08
0.49
0.02
0.94
TRUE
1
CommonMind
Brain Pre-frontal Cortex
HELLS
0.04
0.04
enet
12
0.04
5.1e-06
4.9
5.6
1.7e-08
0.41
0.97
0.01
FALSE
2
GTEx
Ovary
HELLS
0.15
0.04
lasso
5
0.09
3.1e-03
5.0
5.5
3.0e-08
0.34
0.11
0.41
FALSE
3
GTEx
Testis
PIPSL
0.14
0.00
enet
21
0.00
3.0e-01
2.0
-5.3
1.4e-07
-0.38
0.03
0.52
FALSE