Best TWAS P=6.25e-13 · Best GWAS P=2.01e-17 conditioned to 1.3e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PIGC | 0.11 | 0.00 | enet | 21 | 0.01 | 8.4e-02 | -0.67 | 7.2 | 6.2e-13 | 0.40 | 0.06 | 0.16 | TRUE |
| 2 | GTEx | Nerve Tibial | PIGC | 0.10 | 0.02 | enet | 10 | 0.02 | 1.3e-02 | -3.08 | 5.2 | 2.0e-07 | 0.20 | 0.16 | 0.05 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | PIGC | 0.08 | 0.02 | lasso | 5 | 0.02 | 8.8e-03 | 5.15 | 5.4 | 6.6e-08 | -0.07 | 0.52 | 0.02 | TRUE |
| 4 | GTEx | Testis | METTL13 | 0.29 | 0.05 | lasso | 10 | 0.09 | 9.9e-05 | -3.75 | 6.4 | 1.6e-10 | 0.34 | 0.24 | 0.11 | TRUE |