TWAS
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Traits
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Traits
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Whole body fat-free mass
:
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chr15:80,293,439-81,737,095
Best TWAS P=2.91e-08 · Best GWAS P=2.21e-10 conditioned to 0.0639
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Lung Adenocarcinoma
FAM108C1
0.05
0.04
lasso
3
0.04
5.6e-06
5.6
-5.5
2.9e-08
-0.86
0.06
0.94
TRUE
1
NTR
Blood
FAM108C1
0.02
0.01
bslmm
542
0.01
6.1e-03
-3.2
5.3
1.2e-07
0.54
0.06
0.53
TRUE