Best TWAS P=2.12e-10 · Best GWAS P=1.12e-15 conditioned to 3.41e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | RP11-815J21.2 | 0.20 | 0.09 | lasso | 5 | 0.08 | 1.8e-03 | -5.2 | 5.2 | 2.2e-07 | -0.45 | 0.17 | 0.17 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AKAP13 | 0.08 | 0.03 | enet | 11 | 0.08 | 2.3e-08 | -5.7 | -6.4 | 2.1e-10 | 0.41 | 0.13 | 0.86 | TRUE |