[Hub]/) : Traits : Whole body fat-free mass :

chr16:13,697,975-15,886,243

Best TWAS P=8.65e-14 · Best GWAS P=3.62e-11 conditioned to 0.326

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NTAN1 0.05 0.03 lasso 2 0.04 6.7e-04 -6.6 7.0 2.3e-12 -0.93 0.01 0.97 FALSE
2 GTEx Artery Tibial RRN3 0.11 0.06 lasso 2 0.07 2.0e-06 5.6 5.4 7.7e-08 -0.49 0.75 0.23 FALSE
3 GTEx Cells EBV-transformed lymphocytes RRN3 0.36 0.14 lasso 5 0.20 4.5e-07 5.6 5.8 4.9e-09 -0.60 0.19 0.76 FALSE
4 GTEx Cells EBV-transformed lymphocytes RP11-958N24.1 0.22 0.02 lasso 5 0.06 4.8e-03 -2.9 5.3 9.2e-08 -0.60 0.02 0.36 FALSE
5 GTEx Cells Transformed fibroblasts RRN3 0.10 0.12 enet 13 0.13 6.3e-10 5.6 6.3 2.5e-10 -0.59 0.62 0.38 FALSE
6 GTEx Colon Transverse RRN3 0.13 0.00 lasso 5 0.00 1.9e-01 5.4 -5.4 7.7e-08 0.30 0.02 0.32 FALSE
7 GTEx Esophagus Mucosa RRN3 0.13 0.13 lasso 4 0.13 3.2e-09 5.4 5.2 1.9e-07 -0.51 0.76 0.24 FALSE
8 GTEx Heart Atrial Appendage NOMO1 0.19 0.12 lasso 6 0.10 3.7e-05 5.4 5.4 8.5e-08 -0.48 0.22 0.28 FALSE
9 GTEx Heart Atrial Appendage NTAN1 0.10 0.09 lasso 1 0.07 3.7e-04 5.4 5.4 6.9e-08 -0.49 0.04 0.44 FALSE
10 GTEx Heart Left Ventricle RRN3 0.24 0.12 lasso 7 0.17 2.2e-09 5.4 -6.2 4.6e-10 0.39 0.53 0.38 FALSE
11 GTEx Heart Left Ventricle NTAN1 0.09 0.04 lasso 3 0.02 2.0e-02 5.6 5.5 4.1e-08 -0.48 0.02 0.71 FALSE
12 GTEx Muscle Skeletal RRN3 0.18 0.03 enet 17 0.11 5.7e-11 4.3 -5.8 5.1e-09 0.37 0.17 0.70 FALSE
13 GTEx Muscle Skeletal NTAN1 0.12 0.07 lasso 6 0.09 1.4e-09 5.4 6.0 1.8e-09 -0.46 0.79 0.20 FALSE
14 GTEx Nerve Tibial NTAN1 0.07 0.00 enet 14 0.00 1.7e-01 5.6 6.2 5.2e-10 -0.17 0.02 0.18 FALSE
15 GTEx Skin Sun Exposed Lower leg RRN3 0.10 0.12 lasso 1 0.11 4.5e-09 5.6 5.6 2.1e-08 -0.48 0.74 0.26 FALSE
16 GTEx Testis RRN3 0.10 0.10 lasso 2 0.07 3.9e-04 5.6 5.6 2.1e-08 -0.48 0.11 0.15 FALSE
17 GTEx Thyroid RP11-65J21.3 0.35 0.32 lasso 2 0.31 2.6e-24 -5.2 -5.2 1.8e-07 -0.03 0.47 0.53 TRUE
18 NTR Blood NTAN1 0.01 0.00 bslmm 110 0.00 4.2e-02 5.6 6.2 6.3e-10 -0.23 0.02 0.04 FALSE
19 NTR Blood PDXDC1 0.12 0.12 enet 26 0.15 1.3e-46 -6.5 7.5 8.6e-14 -0.84 0.01 0.99 TRUE
20 ROSMAP Brain Pre-frontal Cortex NTAN1 0.12 0.10 lasso 3 0.11 1.4e-13 5.4 5.5 4.8e-08 -0.48 0.84 0.16 FALSE