[Hub]/) : Traits : Whole body fat-free mass :

chr17:36,211,659-37,674,683

Best TWAS P=7.87e-13 · Best GWAS P=1.96e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PIP4K2B 0.15 0.07 lasso 5 0.07 2.2e-06 -7.0 -6.4 2.1e-10 0.92 0.00 1.00 FALSE
2 GTEx Artery Aorta PSMB3 0.23 0.17 enet 26 0.22 2.1e-12 -7.0 -6.3 2.8e-10 0.83 0.00 1.00 FALSE
3 GTEx Artery Tibial PSMB3 0.10 0.02 enet 12 0.03 1.2e-03 -7.0 -6.6 5.3e-11 0.73 0.00 0.99 FALSE
4 GTEx Artery Tibial PIP4K2B 0.37 0.16 enet 49 0.22 2.1e-17 -7.0 -5.3 8.6e-08 0.73 0.00 1.00 FALSE
5 GTEx Esophagus Mucosa CWC25 0.11 0.07 enet 7 0.05 1.5e-04 -5.1 -5.2 1.5e-07 0.48 0.31 0.58 FALSE
6 GTEx Testis PSMB3 0.30 0.24 lasso 4 0.21 8.9e-10 -7.0 -7.2 7.9e-13 0.97 0.00 1.00 TRUE
7 METSIM Adipose PSMB3 0.04 0.02 lasso 5 0.01 2.3e-03 -4.4 -5.5 5.2e-08 0.50 0.14 0.35 FALSE
8 NTR Blood PIP4K2B 0.02 0.01 lasso 3 0.01 6.4e-04 -7.0 7.0 2.8e-12 -0.94 0.00 0.99 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PIP4K2B 0.04 0.01 blup 56 0.03 6.3e-04 -7.0 -5.3 9.2e-08 0.84 0.00 0.95 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma PIP4K2B 0.05 0.04 blup 56 0.05 5.3e-06 -5.2 -6.0 1.9e-09 0.85 0.00 0.99 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMB3 0.12 0.09 lasso 3 0.06 3.0e-03 -7.0 -7.0 1.8e-12 0.99 0.00 0.94 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PSMB3 0.05 0.06 lasso 1 0.05 2.4e-05 -7.0 -7.0 2.3e-12 0.97 0.00 1.00 FALSE