[Hub]/) : Traits : Whole body fat-free mass :

chr17:39,993,748-41,538,783

Best TWAS P=1.25e-08 · Best GWAS P=6.59e-08 conditioned to 0.657

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MLX 0.03 0.03 enet 12 0.02 6.5e-04 -5.4 -5.5 4.3e-08 0.94 0.02 0.97 FALSE
2 GTEx Adipose Subcutaneous HSD17B1P1 0.06 0.09 enet 6 0.09 4.0e-08 -5.1 -5.7 1.2e-08 0.92 0.03 0.97 TRUE
3 GTEx Brain Cerebellum HSD17B1P1 0.17 0.16 lasso 4 0.20 1.7e-06 -5.4 -5.3 1.1e-07 0.95 0.04 0.94 FALSE
4 GTEx Breast Mammary Tissue TUBG2 0.15 0.06 enet 18 0.08 4.5e-05 -5.1 -5.3 1.4e-07 0.94 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue CNTNAP1 0.06 0.03 lasso 2 0.05 9.9e-04 -5.2 5.2 1.6e-07 -0.98 0.02 0.94 FALSE
6 GTEx Colon Sigmoid TUBG2 0.16 0.04 lasso 5 0.05 6.7e-03 -5.4 -5.2 2.4e-07 0.99 0.02 0.91 FALSE
7 GTEx Esophagus Muscularis HSD17B1P1 0.08 0.03 lasso 3 0.01 6.8e-02 -5.1 -5.3 1.3e-07 0.96 0.03 0.88 FALSE
8 GTEx Skin Sun Exposed Lower leg NAGLU 0.08 0.06 enet 9 0.09 5.8e-08 3.8 -5.2 1.5e-07 0.84 0.02 0.97 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma CNTNAP1 0.06 0.05 blup 27 0.03 7.3e-03 -5.3 5.5 3.5e-08 -0.95 0.01 0.95 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NAGLU 0.13 0.02 enet 8 0.04 1.6e-05 3.8 -5.5 4.1e-08 0.78 0.01 0.87 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma CNTNAP1 0.06 0.05 lasso 1 0.04 6.8e-06 -5.2 5.2 2.4e-07 -0.97 0.00 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CNTNAP1 0.06 0.04 blup 27 0.04 8.9e-05 -5.2 5.2 2.0e-07 -0.92 0.00 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma CNTNAP1 0.04 0.03 blup 27 0.05 2.7e-05 -5.1 5.2 2.5e-07 -0.89 0.01 0.97 FALSE