[Hub]/) : Traits : Whole body fat-free mass :

chr19:41,193,580-42,626,207

Best TWAS P=7.67e-11 · Best GWAS P=1.02e-09 conditioned to 0.604

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATP5SL 0.34 0.48 bslmm 365 0.48 1.5e-65 5.9 -5.7 1.4e-08 -0.99 0.01 0.99 FALSE
2 GTEx Artery Aorta ATP5SL 0.14 0.00 lasso 2 0.01 1.6e-01 5.6 -5.6 2.3e-08 -0.98 0.03 0.59 FALSE
3 GTEx Artery Aorta B3GNT8 0.14 0.09 lasso 2 0.08 2.6e-05 6.0 5.3 9.4e-08 0.97 0.01 0.98 FALSE
4 GTEx Artery Aorta CTC-435M10.6 0.16 0.14 lasso 3 0.13 1.3e-07 6.0 5.8 5.9e-09 0.99 0.02 0.98 FALSE
5 GTEx Brain Cerebellar Hemisphere B3GNT8 0.38 0.30 lasso 5 0.23 1.1e-06 6.0 5.8 4.9e-09 0.97 0.01 0.98 FALSE
6 GTEx Brain Cerebellar Hemisphere CTC-435M10.6 0.29 0.20 lasso 4 0.18 2.6e-05 6.0 6.1 9.0e-10 0.99 0.01 0.97 FALSE
7 GTEx Brain Cerebellum B3GNT8 0.28 0.23 lasso 5 0.21 9.2e-07 6.0 5.9 3.8e-09 0.99 0.02 0.98 FALSE
8 GTEx Brain Cerebellum CTC-435M10.6 0.18 0.01 lasso 4 0.03 5.1e-02 5.8 6.1 8.3e-10 0.88 0.02 0.85 FALSE
9 GTEx Brain Frontal Cortex BA9 ATP5SL 0.28 0.15 lasso 3 0.10 1.0e-03 5.6 -5.6 1.9e-08 -0.98 0.02 0.93 FALSE
10 GTEx Cells Transformed fibroblasts B3GNT8 0.10 0.02 lasso 2 0.03 2.0e-03 5.6 5.7 1.6e-08 0.98 0.03 0.96 FALSE
11 GTEx Cells Transformed fibroblasts CTC-435M10.6 0.18 0.16 lasso 2 0.15 4.2e-11 5.6 5.4 6.9e-08 0.96 0.02 0.98 FALSE
12 GTEx Colon Transverse B3GNT8 0.21 0.17 lasso 4 0.18 6.7e-09 5.6 5.6 2.2e-08 0.97 0.03 0.97 FALSE
13 GTEx Colon Transverse CTC-435M10.6 0.26 0.19 enet 19 0.22 5.8e-11 5.5 5.2 2.4e-07 0.91 0.02 0.98 FALSE
14 GTEx Esophagus Muscularis CTC-435M10.6 0.12 0.12 lasso 2 0.10 1.4e-06 5.5 5.4 7.3e-08 0.95 0.03 0.97 FALSE
15 GTEx Lung CTC-435M10.6 0.13 0.11 lasso 3 0.10 3.3e-08 5.6 5.6 1.9e-08 0.98 0.03 0.97 FALSE
16 GTEx Muscle Skeletal EXOSC5 0.07 0.03 enet 6 0.03 4.1e-04 5.8 5.7 1.0e-08 0.98 0.01 0.98 FALSE
17 GTEx Nerve Tibial CTC-435M10.6 0.18 0.15 lasso 6 0.14 5.5e-10 5.5 5.7 1.1e-08 0.98 0.02 0.98 FALSE
18 GTEx Stomach B3GNT8 0.22 0.14 lasso 7 0.12 1.4e-06 5.6 5.6 2.3e-08 0.97 0.02 0.98 FALSE
19 GTEx Testis EXOSC5 0.31 0.33 enet 10 0.33 1.8e-15 5.6 5.7 1.0e-08 0.99 0.02 0.98 FALSE
20 GTEx Thyroid EXOSC5 0.14 0.08 lasso 5 0.05 8.4e-05 5.7 5.3 9.0e-08 0.97 0.04 0.95 FALSE
21 YFS Blood ATP5SL 0.06 0.02 lasso 12 0.03 1.1e-09 6.0 5.6 2.5e-08 0.85 0.01 0.99 FALSE
22 The Cancer Genome Atlas Bladder Urothelial Carcinoma B3GNT8 0.03 0.04 blup 20 0.04 3.2e-04 5.6 5.6 1.8e-08 0.99 0.01 0.96 FALSE
23 The Cancer Genome Atlas Bladder Urothelial Carcinoma BCKDHA 0.02 0.02 lasso 2 0.02 1.5e-02 5.8 -5.8 9.0e-09 -0.99 0.01 0.81 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma B3GNT8 0.04 0.07 blup 20 0.07 1.2e-13 5.6 5.5 4.9e-08 0.98 0.02 0.98 FALSE
25 The Cancer Genome Atlas Colon Adenocarcinoma B3GNT8 0.09 0.13 blup 20 0.11 5.2e-07 5.5 5.2 1.6e-07 0.98 0.02 0.98 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATP5SL 0.04 0.03 enet 12 0.03 1.6e-04 6.1 -5.2 2.3e-07 -0.92 0.00 0.99 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma ATP5SL 0.02 0.03 enet 4 0.02 7.0e-04 5.8 -5.7 1.0e-08 -0.99 0.02 0.89 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma EXOSC5 0.04 0.03 lasso 2 0.02 5.8e-03 6.0 5.8 5.0e-09 0.95 0.01 0.78 FALSE
29 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ATP5SL 0.23 0.05 blup 18 0.05 4.5e-03 6.1 -6.5 7.7e-11 -0.90 0.01 0.85 TRUE
30 The Cancer Genome Atlas Prostate Adenocarcinoma ATP5SL 0.03 0.03 blup 18 0.03 4.1e-04 6.1 -5.8 4.8e-09 -0.99 0.01 0.93 FALSE
31 The Cancer Genome Atlas Rectum Adenocarcinoma B3GNT8 0.39 0.08 blup 20 0.07 1.1e-02 5.8 6.4 1.8e-10 0.85 0.00 0.30 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma ATP5SL 0.02 0.02 blup 18 0.02 3.5e-03 6.1 -5.7 1.1e-08 -0.99 0.01 0.82 FALSE