[Hub]/) : Traits : Whole body fat-free mass :

chr1:200,740,278-202,607,593

Best TWAS P=2.11e-13 · Best GWAS P=3.17e-14 conditioned to 0.644

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PHLDA3 0.16 0.10 lasso 12 0.11 7.2e-13 4.5 5.1 2.8e-07 0.06 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous SHISA4 0.09 0.04 lasso 3 0.03 1.5e-03 -6.0 -6.6 3.4e-11 -0.57 0.19 0.36 TRUE
3 GTEx Esophagus Muscularis LMOD1 0.16 0.09 enet 9 0.08 7.8e-06 7.6 -7.0 2.3e-12 -0.98 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis RP11-307B6.3 0.20 0.12 lasso 3 0.12 5.6e-08 7.6 -6.9 6.0e-12 -0.97 0.01 0.99 FALSE
5 METSIM Adipose LMOD1 0.09 0.07 bslmm 496 0.07 4.8e-10 7.5 -7.1 1.1e-12 -0.96 0.02 0.98 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LMOD1 0.07 0.06 blup 59 0.03 2.1e-02 7.5 -6.7 2.1e-11 -0.90 0.01 0.86 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma LMOD1 0.04 0.07 enet 6 0.05 9.4e-07 -6.6 -7.2 4.5e-13 -0.75 0.23 0.76 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma LMOD1 0.04 0.01 blup 59 0.01 5.7e-02 7.3 -7.3 2.1e-13 -0.83 0.01 0.81 TRUE