[Hub]/) : Traits : Whole body fat-free mass : ← →

chr1:182,298,784-184,739,300

Best TWAS P=7.65e-15 · Best GWAS P=9.57e-17 conditioned to 0.0121

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TSEN15	0.23	0.18	lasso	9	0.18	4.7e-21	7.9	7.8	7.6e-15	0.90	0.02	0.98	TRUE
2	GTEx	Adipose Subcutaneous	RP11-181K3.4	0.09	0.11	enet	9	0.09	6.7e-08	5.7	5.7	1.1e-08	0.04	0.09	0.91	FALSE
3	GTEx	Adipose Visceral Omentum	RP11-181K3.4	0.13	0.06	lasso	3	0.14	8.3e-08	5.8	6.2	5.3e-10	0.04	0.04	0.95	TRUE
4	GTEx	Artery Aorta	RP11-181K3.4	0.17	0.01	enet	16	0.02	2.3e-02	5.7	5.5	3.9e-08	0.06	0.06	0.92	FALSE
5	GTEx	Artery Tibial	LAMC1	0.10	0.10	lasso	5	0.10	2.2e-08	5.7	-5.9	4.0e-09	-0.03	0.07	0.93	FALSE
6	GTEx	Artery Tibial	RP11-181K3.4	0.07	0.07	lasso	15	0.05	1.1e-04	5.7	5.9	3.4e-09	0.06	0.08	0.91	FALSE
7	GTEx	Brain Cerebellar Hemisphere	LAMC1	0.50	0.16	enet	13	0.13	3.8e-04	6.0	5.9	3.8e-09	0.04	0.05	0.94	FALSE
8	GTEx	Brain Cerebellar Hemisphere	TSEN15	0.38	0.08	lasso	13	0.16	5.3e-05	7.9	7.4	1.3e-13	0.83	0.01	0.96	FALSE
9	GTEx	Brain Cerebellum	LAMC1	0.27	0.36	enet	29	0.29	3.5e-09	6.0	5.8	4.8e-09	0.00	0.04	0.96	FALSE
10	GTEx	Esophagus Muscularis	LAMC1	0.11	0.08	enet	9	0.03	4.4e-03	5.8	-5.8	5.7e-09	-0.02	0.07	0.89	FALSE
11	GTEx	Esophagus Muscularis	RP11-181K3.4	0.05	0.09	lasso	1	0.07	3.9e-05	6.0	6.0	1.8e-09	0.03	0.04	0.95	FALSE
12	GTEx	Lung	LAMC1	0.18	0.20	enet	33	0.19	2.3e-14	6.0	-5.8	7.0e-09	-0.04	0.04	0.96	FALSE
13	GTEx	Nerve Tibial	LAMC1	0.07	0.08	enet	30	0.05	1.1e-04	6.0	5.8	5.6e-09	0.07	0.04	0.96	FALSE
14	GTEx	Nerve Tibial	RP11-181K3.4	0.18	0.24	enet	30	0.24	2.9e-17	6.0	5.9	3.6e-09	0.03	0.03	0.97	FALSE
15	GTEx	Thyroid	RP11-181K3.4	0.12	0.07	lasso	4	0.05	5.7e-05	5.7	5.8	7.8e-09	0.05	0.07	0.92	FALSE
16	GTEx	Whole Blood	LAMC1	0.08	0.05	enet	21	0.04	1.0e-04	5.8	5.3	1.1e-07	0.05	0.06	0.94	FALSE
17	METSIM	Adipose	TSEN15	0.06	0.02	enet	28	0.04	1.3e-06	7.9	7.2	7.7e-13	0.76	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GLT25D2	0.05	0.01	enet	10	0.04	6.3e-05	3.9	-7.3	2.0e-13	-0.69	0.01	0.94	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GLT25D2	0.11	0.02	blup	119	0.05	5.1e-06	-1.8	-5.7	1.4e-08	-0.50	0.14	0.31	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LAMC1	0.04	0.03	blup	108	0.04	1.2e-05	6.0	-5.8	9.1e-09	-0.04	0.04	0.95	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	TSEN15	0.11	0.08	blup	52	0.10	6.7e-12	7.9	6.9	4.1e-12	0.78	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	LAMC1	0.06	0.04	blup	109	0.05	1.3e-05	5.8	-5.6	2.5e-08	-0.07	0.04	0.96	FALSE