[Hub]/) : Traits : Whole body fat-free mass :

chr20:46,838,455-48,603,940

Best TWAS P=1.46e-10 · Best GWAS P=4.35e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 5.9 -6.0 2.7e-09 -0.82 0.03 0.97 FALSE
2 GTEx Cells Transformed fibroblasts STAU1 0.08 0.03 lasso 6 0.02 2.3e-02 5.2 5.7 1.5e-08 0.85 0.07 0.80 FALSE
3 GTEx Colon Sigmoid CSE1L 0.18 0.12 lasso 11 0.09 4.4e-04 5.2 -5.3 1.0e-07 -0.80 0.09 0.87 FALSE
4 GTEx Esophagus Mucosa CSE1L 0.09 0.06 lasso 4 0.06 6.9e-05 5.5 -5.3 1.3e-07 -0.80 0.13 0.84 FALSE
5 GTEx Skin Sun Exposed Lower leg CSE1L 0.08 0.03 lasso 2 0.03 9.5e-04 5.7 -5.4 5.4e-08 -0.81 0.29 0.49 FALSE
6 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 5.2 -5.9 4.2e-09 -0.91 0.08 0.92 FALSE
7 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 6.2 -6.4 1.5e-10 -0.98 0.02 0.98 TRUE
8 NTR Blood NCRNA00275 0.07 0.06 lasso 4 0.08 9.7e-25 -3.9 -5.3 8.6e-08 -0.53 1.00 0.00 FALSE
9 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 6.2 -6.4 1.7e-10 -0.96 0.01 0.99 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CSE1L 0.03 0.05 lasso 1 0.03 9.3e-05 5.2 -5.2 2.5e-07 -0.75 0.06 0.92 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CSE1L 0.05 0.07 blup 50 0.07 3.2e-08 5.2 -5.3 1.1e-07 -0.80 0.05 0.95 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 5.9 -6.2 5.5e-10 -0.94 0.00 1.00 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C20orf199 0.05 0.06 lasso 4 0.06 1.0e-04 6.2 6.2 6.1e-10 0.92 0.00 0.96 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma DDX27 0.08 0.05 lasso 3 0.05 1.9e-05 6.2 5.5 3.2e-08 0.85 0.01 0.98 FALSE