Best TWAS P=7.72e-20 · Best GWAS P=2.79e-22 conditioned to 0.000554
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | EFEMP1 | 0.19 | 0.10 | lasso | 8 | 0.08 | 3.7e-03 | -8.3 | -9.1 | 7.7e-20 | 0.78 | 0.04 | 0.70 | TRUE |
| 2 | GTEx | Stomach | SMEK2 | 0.14 | 0.02 | enet | 19 | 0.04 | 3.9e-03 | -2.5 | -5.5 | 2.9e-08 | 0.08 | 0.10 | 0.04 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | EFEMP1 | 0.29 | 0.14 | enet | 37 | 0.19 | 2.2e-24 | -5.0 | -5.4 | 6.2e-08 | 0.64 | 1.00 | 0.00 | FALSE |