TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
←
→
chr2:55,079,242-56,843,605
Best TWAS P=7.72e-20 · Best GWAS P=2.79e-22 conditioned to 0.000554
55M
55.2M
55.4M
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
EFEMP1
0.19
0.10
lasso
8
0.08
3.7e-03
-8.3
-9.1
7.7e-20
0.78
0.04
0.70
TRUE
2
GTEx
Stomach
SMEK2
0.14
0.02
enet
19
0.04
3.9e-03
-2.5
-5.5
2.9e-08
0.08
0.10
0.04
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
EFEMP1
0.29
0.14
enet
37
0.19
2.2e-24
-5.0
-5.4
6.2e-08
0.64
1.00
0.00
FALSE