TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
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→
chr2:207,696,167-209,182,548
Best TWAS P=1.02e-09 · Best GWAS P=3.36e-09 conditioned to 0.000945
207.8M
208M
208.2M
208.4M
208.6M
208.8M
209M
209.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
CREB1
0.15
0.00
enet
7
0.00
2.8e-01
-4.8
-6.1
1.0e-09
-0.50
0.14
0.42
TRUE
1
GTEx
Adipose Subcutaneous
METTL21A
0.10
0.02
lasso
4
0.02
1.6e-02
-4.8
5.7
1.4e-08
0.32
0.20
0.18
FALSE
5
The Cancer Genome Atlas
Breast Invasive Carcinoma
FAM119A
0.04
0.02
blup
51
0.03
1.0e-06
-4.6
5.3
1.1e-07
0.64
0.03
0.96
FALSE
4
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
CREB1
0.03
0.01
blup
64
0.01
2.5e-02
-5.1
-5.3
1.3e-07
-0.49
0.11
0.46
FALSE
3
GTEx
Esophagus Mucosa
METTL21A
0.10
0.10
enet
9
0.12
1.8e-08
-4.8
5.1
2.9e-07
0.57
0.49
0.50
FALSE