[Hub]/) : Traits : Whole body fat-free mass : ← →

chr2:197,560,575-201,571,143

Best TWAS P=2.99e-12 · Best GWAS P=5.87e-14 conditioned to 0.000182

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	-7.1	7.0	3.0e-12	-0.86	0.09	0.91	TRUE
4	GTEx	Brain Hippocampus	FTCDNL1	0.35	0.24	enet	24	0.26	9.0e-07	-3.9	-5.9	3.2e-09	-0.10	0.27	0.30	TRUE
5	GTEx	Brain Nucleus accumbens basal ganglia	C2orf47	0.25	0.01	lasso	3	0.00	2.8e-01	5.2	-5.7	1.3e-08	0.04	0.05	0.46	TRUE
8	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	-6.9	-6.8	1.0e-11	0.86	0.11	0.89	FALSE
15	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	-6.4	-6.7	1.7e-11	0.92	0.15	0.85	FALSE
10	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	-7.1	-6.7	2.1e-11	0.84	0.08	0.40	FALSE
11	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	-7.0	6.6	3.9e-11	-0.82	0.07	0.36	FALSE
13	GTEx	Thyroid	PLCL1	0.04	0.01	lasso	4	0.00	2.6e-01	-6.9	-6.5	1.0e-10	0.76	0.18	0.54	FALSE
2	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	-6.3	-6.1	1.1e-09	0.86	0.30	0.70	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFTN2	0.05	0.01	blup	61	0.02	3.1e-02	-4.4	-6.0	1.6e-09	0.70	0.04	0.40	FALSE
14	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	-7.0	-6.0	1.8e-09	0.80	0.08	0.76	FALSE
12	GTEx	Thyroid	SF3B1	0.04	0.02	enet	14	0.02	2.0e-02	-4.5	-5.9	2.9e-09	0.72	0.10	0.82	FALSE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf60	0.03	0.03	blup	44	0.03	1.8e-04	-5.3	5.7	1.5e-08	-0.05	0.01	0.98	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	1.6	-5.6	1.9e-08	0.65	0.05	0.38	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	TYW5	0.11	0.12	lasso	5	0.11	5.5e-14	-5.4	5.6	2.2e-08	-0.04	0.01	0.99	FALSE
18	YFS	Blood	PLCL1	0.10	0.10	lasso	9	0.14	1.5e-43	-6.5	-5.6	2.3e-08	0.83	0.73	0.27	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TYW5	0.08	0.14	lasso	8	0.13	2.2e-15	-5.4	5.6	2.5e-08	-0.05	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf60	0.04	0.05	lasso	5	0.03	2.1e-03	-5.4	5.4	5.9e-08	-0.04	0.01	0.91	FALSE
6	GTEx	Breast Mammary Tissue	SF3B1	0.06	0.06	lasso	4	0.03	6.6e-03	-4.4	-5.4	6.3e-08	0.61	0.16	0.68	FALSE
7	GTEx	Breast Mammary Tissue (Female)	SF3B1	0.05	-0.01	lasso	3	-0.01	8.1e-01	-4.3	-5.4	8.1e-08	0.65	0.05	0.10	FALSE
3	GTEx	Brain Caudate basal ganglia	TYW5	0.23	0.11	lasso	3	0.11	5.4e-04	-4.6	5.4	8.4e-08	-0.03	0.04	0.62	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	C2orf69	0.07	0.04	enet	13	0.06	3.6e-08	-5.1	5.4	8.5e-08	-0.05	0.04	0.96	FALSE