TWAS
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Traits
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Traits
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Whole body fat-free mass
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chr2:223,221,391-225,959,850
Best TWAS P=9.39e-09 · Best GWAS P=3.23e-17 conditioned to 6.14e-10
223.5M
224M
224.5M
225M
225.5M
226M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Muscle Skeletal
KCNE4
0.06
0.01
lasso
2
0.00
2.4e-01
-5.7
-5.7
9.4e-09
0.41
0.19
0.06
TRUE
2
GTEx
Adrenal Gland
FAM124B
0.31
0.17
lasso
4
0.17
9.2e-07
5.1
-5.3
9.9e-08
0.09
0.02
0.95
TRUE
1
GTEx
Adipose Subcutaneous
FAM124B
0.08
0.00
lasso
4
0.00
4.6e-01
5.7
-5.3
1.2e-07
0.11
0.02
0.80
FALSE