[Hub]/) : Traits : Whole body fat-free mass : ← →

chr2:231,628,878-234,434,621

Best TWAS P=1.05e-15 · Best GWAS P=2.97e-12 conditioned to 0.531

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	PTMA	0.28	0.12	enet	19	0.06	1.5e-02	-5.4	5.5	3.3e-08	-0.48	0.05	0.52	FALSE
2	GTEx	Brain Frontal Cortex BA9	C2orf82	0.24	0.16	lasso	10	0.12	3.9e-04	-4.8	5.6	1.7e-08	0.02	0.04	0.93	FALSE
3	GTEx	Brain Putamen basal ganglia	C2orf82	0.28	0.22	lasso	3	0.18	5.3e-05	-4.8	5.7	1.0e-08	0.01	0.04	0.78	FALSE
4	GTEx	Heart Atrial Appendage	COPS7B	0.22	0.01	lasso	6	0.01	1.3e-01	-5.4	-6.0	2.4e-09	0.66	0.05	0.23	FALSE
5	GTEx	Liver	PDE6D	0.21	0.10	lasso	4	0.09	1.8e-03	-7.0	-7.4	1.1e-13	0.81	0.01	0.90	TRUE
6	GTEx	Thyroid	GIGYF2	0.08	0.02	lasso	3	0.01	6.7e-02	-6.3	-5.6	1.7e-08	-0.02	0.06	0.49	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	NCL	0.16	0.05	lasso	6	0.08	6.1e-10	3.9	6.4	1.8e-10	0.06	0.01	0.99	TRUE
8	ROSMAP	Brain Pre-frontal Cortex	LINC00471	0.34	0.26	lasso	10	0.36	2.1e-48	-5.9	5.2	1.7e-07	-0.04	0.18	0.82	FALSE
9	YFS	Blood	EIF4E2	0.06	0.04	enet	27	0.04	2.8e-13	4.6	5.2	2.4e-07	-0.04	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C2orf52	0.15	0.14	enet	8	0.13	3.7e-11	-6.1	6.0	1.7e-09	-0.02	0.10	0.90	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	C2orf52	0.19	0.22	blup	42	0.25	4.1e-50	-5.9	5.1	3.0e-07	-0.02	0.07	0.93	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	DIS3L2	0.05	0.02	enet	10	0.02	3.8e-05	-3.4	-5.4	6.4e-08	0.15	0.10	0.02	TRUE
13	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C2orf52	0.28	0.12	lasso	6	0.12	2.0e-06	-6.4	6.5	8.6e-11	-0.04	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	C2orf52	0.21	0.16	blup	42	0.24	7.1e-14	-5.9	6.1	1.4e-09	0.00	0.06	0.94	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	C2orf52	0.28	0.12	enet	12	0.18	5.0e-06	-6.1	6.2	5.6e-10	-0.03	0.03	0.87	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C2orf52	0.23	0.25	enet	12	0.28	2.9e-32	-6.0	5.7	1.5e-08	-0.03	0.16	0.84	FALSE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C2orf52	0.18	0.20	lasso	3	0.19	3.4e-11	-5.9	5.9	4.0e-09	-0.02	0.08	0.92	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EFHD1	0.11	0.01	blup	70	0.03	1.0e-02	5.9	8.0	1.0e-15	-0.03	0.02	0.72	TRUE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	KCNJ13	0.07	0.06	enet	13	0.05	4.7e-04	-6.7	5.8	6.6e-09	0.01	0.02	0.92	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	C2orf82	0.14	0.20	enet	6	0.19	3.1e-21	-4.9	5.2	2.1e-07	0.01	1.00	0.00	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIGYF2	0.02	0.01	lasso	3	0.01	5.3e-02	-6.7	-6.8	1.2e-11	-0.02	0.03	0.88	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	NGEF	0.03	0.01	blup	130	0.01	2.0e-02	-6.7	5.7	1.5e-08	0.01	0.02	0.90	FALSE
23	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C2orf52	0.13	0.06	lasso	4	0.05	2.1e-03	-6.1	6.0	2.2e-09	-0.03	0.03	0.56	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf52	0.18	0.16	enet	12	0.19	3.0e-21	-6.1	5.4	6.7e-08	-0.03	0.08	0.92	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	CHRNG	0.04	0.00	blup	58	0.00	1.3e-01	2.1	-5.2	2.2e-07	0.12	0.00	0.14	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C2orf52	0.28	0.18	lasso	4	0.20	3.7e-22	-6.4	6.1	1.4e-09	-0.05	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf52	0.24	0.20	lasso	3	0.20	1.4e-13	-5.9	5.8	4.8e-09	-0.02	0.11	0.89	FALSE
28	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C2orf52	0.32	0.21	lasso	7	0.21	3.6e-09	-5.8	5.8	8.2e-09	-0.06	0.05	0.95	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	KCNJ13	0.07	0.07	blup	36	0.06	2.4e-03	-6.7	6.3	3.3e-10	0.02	0.01	0.87	FALSE
30	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C2orf52	0.27	0.27	lasso	5	0.28	1.7e-11	-6.1	6.1	8.1e-10	-0.01	0.07	0.93	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	C2orf52	0.32	0.34	blup	42	0.39	9.3e-44	-5.9	5.4	6.1e-08	0.00	0.03	0.97	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	GIGYF2	0.04	0.00	blup	103	0.02	2.1e-03	-4.9	-6.0	1.6e-09	0.01	0.04	0.81	FALSE
33	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C2orf52	0.21	0.20	lasso	1	0.18	1.4e-05	-6.4	6.4	1.7e-10	-0.02	0.02	0.82	FALSE
34	The Cancer Genome Atlas	Stomach Adenocarcinoma	C2orf52	0.12	0.10	enet	11	0.12	5.6e-09	-5.9	5.7	1.5e-08	0.00	0.04	0.96	FALSE
35	The Cancer Genome Atlas	Stomach Adenocarcinoma	KCNJ13	0.09	0.06	blup	36	0.08	3.8e-06	-6.7	5.4	7.2e-08	0.02	0.01	0.98	FALSE
36	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C2orf52	0.29	0.17	enet	10	0.19	3.2e-07	-6.1	5.9	2.9e-09	-0.04	0.04	0.94	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	C2orf52	0.45	0.31	enet	10	0.35	4.9e-35	-5.8	5.1	2.9e-07	-0.01	0.24	0.76	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	KCNJ13	0.03	0.00	blup	35	0.01	4.3e-02	6.0	-7.5	7.9e-14	-0.02	0.01	0.55	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	NGEF	0.04	0.03	enet	7	0.03	5.6e-04	6.0	-7.1	1.0e-12	0.00	0.04	0.93	FALSE