Best TWAS P=4.47e-12 · Best GWAS P=4.14e-11 conditioned to 0.0938
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DHX36 | 0.05 | 0.06 | blup | 357 | 0.05 | 1.3e-06 | -5.3 | -5.9 | 3.3e-09 | -0.49 | 0.93 | 0.07 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | ARHGEF26 | 0.10 | 0.06 | enet | 8 | 0.07 | 2.2e-06 | -5.3 | 5.4 | 6.6e-08 | 0.39 | 0.91 | 0.07 | FALSE |
| 3 | GTEx | Ovary | ARHGEF26 | 0.14 | 0.03 | enet | 15 | 0.06 | 1.4e-02 | 6.6 | 6.9 | 4.5e-12 | 0.81 | 0.03 | 0.75 | TRUE |
| 4 | GTEx | Pancreas | ARHGEF26 | 0.26 | 0.26 | lasso | 5 | 0.28 | 3.2e-12 | -5.2 | 6.2 | 6.1e-10 | 0.48 | 0.92 | 0.08 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | ARHGEF26 | 0.13 | 0.11 | lasso | 4 | 0.07 | 6.8e-05 | -5.2 | 5.8 | 9.0e-09 | 0.45 | 0.84 | 0.12 | FALSE |
| 6 | GTEx | Thyroid | ARHGEF26 | 0.09 | 0.07 | enet | 17 | 0.08 | 1.9e-06 | -5.4 | 5.7 | 1.6e-08 | 0.44 | 0.80 | 0.14 | FALSE |
| 7 | METSIM | Adipose | ARHGEF26 | 0.07 | 0.08 | lasso | 6 | 0.07 | 3.5e-11 | -5.3 | 5.5 | 3.8e-08 | 0.45 | 0.95 | 0.05 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SGEF | 0.04 | 0.04 | enet | 12 | 0.04 | 1.1e-05 | -5.0 | 6.0 | 2.4e-09 | 0.50 | 0.41 | 0.45 | FALSE |
| 9 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DHX36 | 0.11 | 0.09 | enet | 11 | 0.10 | 6.4e-12 | -4.7 | -5.3 | 1.1e-07 | -0.51 | 0.99 | 0.01 | FALSE |