[Hub]/) : Traits : Whole body fat-free mass :

chr3:153,142,317-154,733,231

Best TWAS P=4.47e-12 · Best GWAS P=4.14e-11 conditioned to 0.0938

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -5.3 -5.9 3.3e-09 -0.49 0.93 0.07 FALSE
2 GTEx Adipose Subcutaneous ARHGEF26 0.10 0.06 enet 8 0.07 2.2e-06 -5.3 5.4 6.6e-08 0.39 0.91 0.07 FALSE
3 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 6.6 6.9 4.5e-12 0.81 0.03 0.75 TRUE
4 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -5.2 6.2 6.1e-10 0.48 0.92 0.08 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic ARHGEF26 0.13 0.11 lasso 4 0.07 6.8e-05 -5.2 5.8 9.0e-09 0.45 0.84 0.12 FALSE
6 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -5.4 5.7 1.6e-08 0.44 0.80 0.14 FALSE
7 METSIM Adipose ARHGEF26 0.07 0.08 lasso 6 0.07 3.5e-11 -5.3 5.5 3.8e-08 0.45 0.95 0.05 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -5.0 6.0 2.4e-09 0.50 0.41 0.45 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -4.7 -5.3 1.1e-07 -0.51 0.99 0.01 FALSE