Best TWAS P=3.77e-18 · Best GWAS P=2.83e-28 conditioned to 1.25e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FNDC3B | 0.07 | 0.06 | enet | 8 | 0.05 | 3.2e-07 | -9.24 | 8.7 | 3.8e-18 | 0.04 | 0.97 | 0.00 | TRUE |
| 2 | GTEx | Ovary | TNFSF10 | 0.40 | 0.01 | lasso | 10 | 0.05 | 1.8e-02 | 0.95 | 6.3 | 3.4e-10 | 0.41 | 0.03 | 0.49 | TRUE |
| 3 | YFS | Blood | TNFSF10 | 0.09 | 0.04 | bslmm | 462 | 0.08 | 1.6e-24 | 7.28 | 7.1 | 1.2e-12 | 0.38 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FNDC3B | 0.07 | 0.02 | enet | 6 | 0.02 | 3.9e-03 | 7.65 | -7.8 | 4.6e-15 | -0.83 | 0.01 | 0.98 | TRUE |