Best TWAS P=3.32e-09 · Best GWAS P=1.13e-07 conditioned to 0.651
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -5.3 | 5.7 | 1.1e-08 | -0.98 | 0.01 | 0.99 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | REST | 0.04 | 0.02 | bslmm | 536 | 0.02 | 3.4e-03 | -5.3 | -5.3 | 1.1e-07 | 0.58 | 0.02 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -5.3 | -5.9 | 3.3e-09 | 0.86 | 0.01 | 0.95 | TRUE |